L. Hernandez - Academia.edu (original) (raw)
Papers by L. Hernandez
Lecture Notes in Computer Science, 1993
The multi-agent system paradigm emerges as an interesting approach in the Knowledge-Based System ... more The multi-agent system paradigm emerges as an interesting approach in the Knowledge-Based System (KBS) field, when distributed problem-solving techniques are required for solving problems that can be represented as a collection of groups of cooperating ...
2006 IEEE International Symposium on Circuits and Systems, 2006
A 1.5-V Square-Root Domain (SRD) first-order filter possessing multiple operating points is prese... more A 1.5-V Square-Root Domain (SRD) first-order filter possessing multiple operating points is presented. The basic building blocks of the filter are based on MOS translinear loops and dynamic level shifter techniques, allowing low voltage operation and an extended dynamic range. However the dynamic level shifters introduce positive feedback inducing three operating points to the filter through a negative differential resistance. A detailed analysis of such performance employing a bi-port analysis is offered. Simulation and measurement results are provided in order to demonstrate the analysis and circuits proposed. ISCAS 2006 0-7803-9390-2
Physiology & Behavior, 1991
Two experiments were conducted in order to see if dopamine satiety receptors in the lateral hypot... more Two experiments were conducted in order to see if dopamine satiety receptors in the lateral hypothalamus or satiety mechanisms in the ventromedial hypothalamus were involved in the hyperphagia and body weight increase induced by systemic sulpiride. In the first experiment, it was shown that systemic sulpiride (20 mg/kg) does not block the anorexia caused by intraperifornical injections of amphetamine. In the second experiment, sulpiride (20 mg/kg during 18 days) did not produce an additional increase in body weight in previously VMH-lesioned female rats. This last fact cannot be explained by a ceiling effect since insulin (5 U/day during 7 days) increased body weight in the same VMH rats in which sulpiride was not effective. These results do not support the hypothesis that systemic sulpiride reaches the perifornical dopamine D2 receptors to disinhibit feeding, but suggest instead an involvement of the ventromedial hypothalamus. This last suggestion is more in agreement with the hypothesis that sulpiride alters feeding and body weight gain through the induction of a functional gonadectomy.
Medical Care, 1998
There is a need in the United States for culture-equivalent assessment of health-related quality ... more There is a need in the United States for culture-equivalent assessment of health-related quality of life, particularly among people who speak different languages and among those with low literacy skills. This report summarizes the adaptation of the Functional Assessment of Cancer Therapy (FACT) Scales for use with Spanish-speaking cancer patients, including those with low literacy. The Spanish language version of the general Functional Assessment of Cancer Therapy scale plus five disease-specific subscales (breast, lung, colorectal, head and neck, HIV infection) were translated, reviewed, and revised, then evaluated in interviews with Spanish-speaking patients from the mainland United States and Puerto Rico. An iterative forward-backward-forward sequence of item translation, expert bilingual/bicultural advisor review, pretesting interviews with 92 patients, and further expert advisory input were used to establish semantic, content, and partial technical equivalence. The Functional Assessment of Cancer Therapy-General and five disease-specific subscales were translated successfully into wording that was easily understood and answered, leading to psychometric and scoring data similar to that of the English version. All but one of the 28 Functional Assessment of Cancer Therapy-General items and all of the disease-specific items were seen as culturally relevant. The result is a document that underwent iterative forward-backward translation and evaluation and was pretested successfully with native Spanish-speaking oncology patients living in the Central United States and Puerto Rico. The Functional Assessment of Cancer Therapy-General and five disease-specific subscales have been translated successfully into Spanish using a thorough translation and initial validation methodology. The methods and data provide a model for preparing a health status questionnaire for cross-cultural validation. The questionnaire is available for use in clinical trials and clinical practice.
Leadership Quarterly, 1996
We present a new way to approach obtaining the range map in triangulation range finders. Among th... more We present a new way to approach obtaining the range map in triangulation range finders. Among the advantages that it presents is that it avoids A/D conversion of the signal provided by the image sensor and posterior complex digital signal processing. The main idea is to use analog circuits to directly detect the pixel with maximum light intensity. Synchronization signals
Human Immunology, 2010
Celiac disease (CD) is an autoimmune disorder that is triggered by an immune response to gluten i... more Celiac disease (CD) is an autoimmune disorder that is triggered by an immune response to gluten in genetically predisposed individuals. Although considered a primary gastrointestinal disease, CD is now known to have widespread systemic manifestations. We attempted to define the nature and role of systemic cytokine levels in the pathophysiology of CD. Multiplex cytokine assays were performed on four different groups of adult patients; patients with active CD (ACD), patients on a gluten-free diet (GFD) with positive TTG IgA antibodies, patients on a GFD with negative antibodies, and those with refractory CD (RCD). The results were compared with values in healthy adult controls. Patients with active CD and those on GFD with positive antibodies had significantly higher levels of proinflammatory cytokines, such as interferon-␥, interleukin (IL)-1, tumor necrosis factor-␣, IL-6 and IL-8, and also T h -2 cytokines such as IL-4 and IL-10, compared with normal controls and patients on GFD without antibodies. Interestingly patients on GFD for less than 1 year had significantly higher levels of both proinflammatory cytokines and T h 2 cytokines compared with the patients on GFD for more than 1 year. In addition, a statistically significant correlation between levels of TTG IgA titers and serum levels of T h -2 cytokines IL-4 (p Ͻ 0.001), IL-10 (p Ͻ 0.001) and inflammatory cytokines such as IL-1␣ (p Ͻ 0.001), IL-1 (p Ͻ 0.005), and IL-8 (p Ͻ 0.05) was observed. ᭧
Gynecological Endocrinology, 2011
Data on social and personal aspects of Central America are lacking in relation to hormone therapy... more Data on social and personal aspects of Central America are lacking in relation to hormone therapy (HT) and other treatments for the menopause. To gain information regarding the treatment of the menopause (HT/alternative): use, knowledge, perceptions and attitudes among middle-aged Central American women. A total of 720 urban living women (35-65 years) from six Central American countries (Guatemala, El Salvador, Honduras, Nicaragua, Costa Rica and Panama) were surveyed with a structured questionnaire that included socio-demographic data and information regarding the menopause and its treatment. Participating countries displayed significant socio-demographic differences. Forty-one percent of all women were postmenopausal and 5.8% had no education at all. Knowledge regarding menopausal treatment options varied; while 27.2% (196/720) indicated HT as an option a higher rate (36.3%) either did not respond or answered not knowing anything. HT use for the whole sample was rather low 2.7% with differences seen among countries. 13.8% (27/196) indicated to have been on HT but abandoned treatment because of medical indication (51.9%), undesired side effects (29.6%) and costs (11.1%). While more than 50% considered HT served to replace hormones a smaller percentage (<14%) referred HT as bad for health, reduces cancer risk or has many side effects. 9.3% (67/720) acknowledged the existence of phytoestrogens as a menopausal treatment option, considering them as natural estrogens and good for health in 38.8% and 25.4%, respectively. HT use in this mid-aged series was rather low in which the demography of Central America may be related factors. Education to women and physicians should be encouraged.
Drug Development and Industrial Pharmacy, 1991
Crystal Research and Technology, 1982
Temperature and Intensity Behaviour of the pAlo.,Gao.sAs-pGnAs-nGaAs Concentrator Solar Cell A se... more Temperature and Intensity Behaviour of the pAlo.,Gao.sAs-pGnAs-nGaAs Concentrator Solar Cell A selniccnpirical approdl for calculation of pAlo.7Gao sAs-pGaAs-iiGtlAs concentrator solar cell behaviour in a very wide range of operating temperatures (77 K-490 H) is developed. Experimental values of cell collection efficiency, short circuit current and open circuit voltage are given, while cell fill factor and overall conversion efficiency are calculated. Optimum cell operating conditions are found both for AM 1 and AM 0 radiation. ]BbI~MCJIeHHe IIapaMeTpOB 3KnJlyaTaUHM COJIHeI-HOTO (POT03JIeMeHTa TMIIB pA10,7Ga0,3As--pGaAs-nGaAs npll pa3JIH' lHbIX J' pOBHRX OCBeUeHllR JJpOBOAHTCR B lUVlpoKoM nMana3oHe TeMnepaTyp (77 K--490 K). BHYTpeHHhIfi KBaHTOBhIfi BbIXOA, TOK KOpOTIEOrO 3aMbIIEaHMR I1 HanpRHceHVle XOJIOCTOI'O XOAa (PoTO3JIeMeHTa oIIpe~eJIfl€OTCR 3KCnepMMeHTaJILH0, a K03@@MqHeHT 3anOJIbHeHVlR BOJIhT aMllepHofi XapaKTepHCTHKll M H n f i BhlYHCJIRIOTCSI. -Coo61qam~c~ OnTVlMaJILbIIIbIe YCJIOBHR s~c n n y a~a u m npll6opa npM AM 0 H AM 1 ocBeIqeHHRx.
CHEST Journal, 1998
and services can be found online on the World Wide Web at:
lpi.usra.edu
... 1 , Suzi Romero ... Lucey, PG, Gillis-Davis, JT, Hawke, BR,Taylor, LA, Duke, MB, Brady, T., M... more ... 1 , Suzi Romero ... Lucey, PG, Gillis-Davis, JT, Hawke, BR,Taylor, LA, Duke, MB, Brady, T., Mosher, T., LEAG Review of Constellation Program Regions of Interest for Human Exploration of the Moon, Lunar Reconnaissance Orbiter Science Targeting Meeting (2009). ...
Praxis Investigativa REDIE, 2014
Lecture Notes in Computer Science, 1993
The multi-agent system paradigm emerges as an interesting approach in the Knowledge-Based System ... more The multi-agent system paradigm emerges as an interesting approach in the Knowledge-Based System (KBS) field, when distributed problem-solving techniques are required for solving problems that can be represented as a collection of groups of cooperating ...
2006 IEEE International Symposium on Circuits and Systems, 2006
A 1.5-V Square-Root Domain (SRD) first-order filter possessing multiple operating points is prese... more A 1.5-V Square-Root Domain (SRD) first-order filter possessing multiple operating points is presented. The basic building blocks of the filter are based on MOS translinear loops and dynamic level shifter techniques, allowing low voltage operation and an extended dynamic range. However the dynamic level shifters introduce positive feedback inducing three operating points to the filter through a negative differential resistance. A detailed analysis of such performance employing a bi-port analysis is offered. Simulation and measurement results are provided in order to demonstrate the analysis and circuits proposed. ISCAS 2006 0-7803-9390-2
Physiology & Behavior, 1991
Two experiments were conducted in order to see if dopamine satiety receptors in the lateral hypot... more Two experiments were conducted in order to see if dopamine satiety receptors in the lateral hypothalamus or satiety mechanisms in the ventromedial hypothalamus were involved in the hyperphagia and body weight increase induced by systemic sulpiride. In the first experiment, it was shown that systemic sulpiride (20 mg/kg) does not block the anorexia caused by intraperifornical injections of amphetamine. In the second experiment, sulpiride (20 mg/kg during 18 days) did not produce an additional increase in body weight in previously VMH-lesioned female rats. This last fact cannot be explained by a ceiling effect since insulin (5 U/day during 7 days) increased body weight in the same VMH rats in which sulpiride was not effective. These results do not support the hypothesis that systemic sulpiride reaches the perifornical dopamine D2 receptors to disinhibit feeding, but suggest instead an involvement of the ventromedial hypothalamus. This last suggestion is more in agreement with the hypothesis that sulpiride alters feeding and body weight gain through the induction of a functional gonadectomy.
Medical Care, 1998
There is a need in the United States for culture-equivalent assessment of health-related quality ... more There is a need in the United States for culture-equivalent assessment of health-related quality of life, particularly among people who speak different languages and among those with low literacy skills. This report summarizes the adaptation of the Functional Assessment of Cancer Therapy (FACT) Scales for use with Spanish-speaking cancer patients, including those with low literacy. The Spanish language version of the general Functional Assessment of Cancer Therapy scale plus five disease-specific subscales (breast, lung, colorectal, head and neck, HIV infection) were translated, reviewed, and revised, then evaluated in interviews with Spanish-speaking patients from the mainland United States and Puerto Rico. An iterative forward-backward-forward sequence of item translation, expert bilingual/bicultural advisor review, pretesting interviews with 92 patients, and further expert advisory input were used to establish semantic, content, and partial technical equivalence. The Functional Assessment of Cancer Therapy-General and five disease-specific subscales were translated successfully into wording that was easily understood and answered, leading to psychometric and scoring data similar to that of the English version. All but one of the 28 Functional Assessment of Cancer Therapy-General items and all of the disease-specific items were seen as culturally relevant. The result is a document that underwent iterative forward-backward translation and evaluation and was pretested successfully with native Spanish-speaking oncology patients living in the Central United States and Puerto Rico. The Functional Assessment of Cancer Therapy-General and five disease-specific subscales have been translated successfully into Spanish using a thorough translation and initial validation methodology. The methods and data provide a model for preparing a health status questionnaire for cross-cultural validation. The questionnaire is available for use in clinical trials and clinical practice.
Leadership Quarterly, 1996
We present a new way to approach obtaining the range map in triangulation range finders. Among th... more We present a new way to approach obtaining the range map in triangulation range finders. Among the advantages that it presents is that it avoids A/D conversion of the signal provided by the image sensor and posterior complex digital signal processing. The main idea is to use analog circuits to directly detect the pixel with maximum light intensity. Synchronization signals
Human Immunology, 2010
Celiac disease (CD) is an autoimmune disorder that is triggered by an immune response to gluten i... more Celiac disease (CD) is an autoimmune disorder that is triggered by an immune response to gluten in genetically predisposed individuals. Although considered a primary gastrointestinal disease, CD is now known to have widespread systemic manifestations. We attempted to define the nature and role of systemic cytokine levels in the pathophysiology of CD. Multiplex cytokine assays were performed on four different groups of adult patients; patients with active CD (ACD), patients on a gluten-free diet (GFD) with positive TTG IgA antibodies, patients on a GFD with negative antibodies, and those with refractory CD (RCD). The results were compared with values in healthy adult controls. Patients with active CD and those on GFD with positive antibodies had significantly higher levels of proinflammatory cytokines, such as interferon-␥, interleukin (IL)-1, tumor necrosis factor-␣, IL-6 and IL-8, and also T h -2 cytokines such as IL-4 and IL-10, compared with normal controls and patients on GFD without antibodies. Interestingly patients on GFD for less than 1 year had significantly higher levels of both proinflammatory cytokines and T h 2 cytokines compared with the patients on GFD for more than 1 year. In addition, a statistically significant correlation between levels of TTG IgA titers and serum levels of T h -2 cytokines IL-4 (p Ͻ 0.001), IL-10 (p Ͻ 0.001) and inflammatory cytokines such as IL-1␣ (p Ͻ 0.001), IL-1 (p Ͻ 0.005), and IL-8 (p Ͻ 0.05) was observed. ᭧
Gynecological Endocrinology, 2011
Data on social and personal aspects of Central America are lacking in relation to hormone therapy... more Data on social and personal aspects of Central America are lacking in relation to hormone therapy (HT) and other treatments for the menopause. To gain information regarding the treatment of the menopause (HT/alternative): use, knowledge, perceptions and attitudes among middle-aged Central American women. A total of 720 urban living women (35-65 years) from six Central American countries (Guatemala, El Salvador, Honduras, Nicaragua, Costa Rica and Panama) were surveyed with a structured questionnaire that included socio-demographic data and information regarding the menopause and its treatment. Participating countries displayed significant socio-demographic differences. Forty-one percent of all women were postmenopausal and 5.8% had no education at all. Knowledge regarding menopausal treatment options varied; while 27.2% (196/720) indicated HT as an option a higher rate (36.3%) either did not respond or answered not knowing anything. HT use for the whole sample was rather low 2.7% with differences seen among countries. 13.8% (27/196) indicated to have been on HT but abandoned treatment because of medical indication (51.9%), undesired side effects (29.6%) and costs (11.1%). While more than 50% considered HT served to replace hormones a smaller percentage (<14%) referred HT as bad for health, reduces cancer risk or has many side effects. 9.3% (67/720) acknowledged the existence of phytoestrogens as a menopausal treatment option, considering them as natural estrogens and good for health in 38.8% and 25.4%, respectively. HT use in this mid-aged series was rather low in which the demography of Central America may be related factors. Education to women and physicians should be encouraged.
Drug Development and Industrial Pharmacy, 1991
Crystal Research and Technology, 1982
Temperature and Intensity Behaviour of the pAlo.,Gao.sAs-pGnAs-nGaAs Concentrator Solar Cell A se... more Temperature and Intensity Behaviour of the pAlo.,Gao.sAs-pGnAs-nGaAs Concentrator Solar Cell A selniccnpirical approdl for calculation of pAlo.7Gao sAs-pGaAs-iiGtlAs concentrator solar cell behaviour in a very wide range of operating temperatures (77 K-490 H) is developed. Experimental values of cell collection efficiency, short circuit current and open circuit voltage are given, while cell fill factor and overall conversion efficiency are calculated. Optimum cell operating conditions are found both for AM 1 and AM 0 radiation. ]BbI~MCJIeHHe IIapaMeTpOB 3KnJlyaTaUHM COJIHeI-HOTO (POT03JIeMeHTa TMIIB pA10,7Ga0,3As--pGaAs-nGaAs npll pa3JIH' lHbIX J' pOBHRX OCBeUeHllR JJpOBOAHTCR B lUVlpoKoM nMana3oHe TeMnepaTyp (77 K--490 K). BHYTpeHHhIfi KBaHTOBhIfi BbIXOA, TOK KOpOTIEOrO 3aMbIIEaHMR I1 HanpRHceHVle XOJIOCTOI'O XOAa (PoTO3JIeMeHTa oIIpe~eJIfl€OTCR 3KCnepMMeHTaJILH0, a K03@@MqHeHT 3anOJIbHeHVlR BOJIhT aMllepHofi XapaKTepHCTHKll M H n f i BhlYHCJIRIOTCSI. -Coo61qam~c~ OnTVlMaJILbIIIbIe YCJIOBHR s~c n n y a~a u m npll6opa npM AM 0 H AM 1 ocBeIqeHHRx.
CHEST Journal, 1998
and services can be found online on the World Wide Web at:
lpi.usra.edu
... 1 , Suzi Romero ... Lucey, PG, Gillis-Davis, JT, Hawke, BR,Taylor, LA, Duke, MB, Brady, T., M... more ... 1 , Suzi Romero ... Lucey, PG, Gillis-Davis, JT, Hawke, BR,Taylor, LA, Duke, MB, Brady, T., Mosher, T., LEAG Review of Constellation Program Regions of Interest for Human Exploration of the Moon, Lunar Reconnaissance Orbiter Science Targeting Meeting (2009). ...
Praxis Investigativa REDIE, 2014