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Papers by Lactatia Motsuku

Research Square (Research Square), Oct 7, 2020

BMC Cancer, Feb 6, 2021

Background: South Africa (SA) has experienced a rapid transition in the Human Development Index (... more Background: South Africa (SA) has experienced a rapid transition in the Human Development Index (HDI) over the past decade, which had an effect on the incidence and mortality rates of colorectal cancer (CRC). This study aims to provide CRC incidence and mortality trends by population group and sex in SA from 2002 to 2014. Methods: Incidence data were extracted from the South African National Cancer Registry and mortality data obtained from Statistics South Africa (STATS SA), for the period 2002 to 2014. Age-standardised incidence rates (ASIR) and age-standardised mortality rates (ASMR) were calculated using the STATS SA midyear population as the denominator and the Segi world standard population data for standardisation. A Joinpoint regression analysis was computed for the CRC ASIR and ASMR by population group and sex. Results: A total of 33,232 incident CRC cases and 26,836 CRC deaths were reported during the study period. Of the CRC cases reported, 54% were males and 46% were females, and among deaths reported, 47% were males and 53% were females. Overall, there was a 2.5% annual average percentage change (AAPC) increase in ASIR from 2002 to 2014 (95% CI: 0.6-4.5, p-value < 0.001). For ASMR overall, there was 1.3% increase from 2002 to 2014 (95% CI: 0.1-2.6, p-value < 0.001). The ASIR and ASMR among population groups were stable, with the exception of the Black population group. The ASIR increased consistently at 4.3% for black males (95% CI: 1.9-6.7, p-value < 0.001) and 3.4% for black females (95% CI: 1.5-5.3, p-value < 0.001) from 2002 to 2014, respectively. Similarly, ASMR for black males and females increased by 4.2% (95% CI: 2.0-6.5, p-value < 0.001) and 3.4% (, 95%CI: 2.0-4.8, p-value < 0.01) from 2002 to 2014, respectively. Conclusions: The disparities in the CRC incidence and mortality trends may reflect socioeconomic inequalities across different population groups in SA. The rapid increase in CRC trends among the Black population group is concerning and requires further investigation and increased efforts for cancer prevention, early screening and diagnosis, as well as better access to cancer treatment.

Journal of Global Oncology, 2018

Background: South Africa (SA) recently established an urban population-based cancer registry in E... more Background: South Africa (SA) recently established an urban population-based cancer registry in Ekurhuleni metropolitan district in Gauteng Province. The Ekurhuleni Population-Based Cancer Registry (EPBCR) aims to inform cancer policy and comprehensive cancer control programs. The registry covers 3.5 million residents including public/private, rural/urban patients and a mix of the multiethnic SA population. The first complete…

of poster submission for Carpentry Conference 2018 by the African Task Force members.

Slides from my presentation at International Data Week SciDataCon, Gaborone, 2018.<br>The p... more Slides from my presentation at International Data Week SciDataCon, Gaborone, 2018.<br>The presentation took place in session 244: Sharing lessons on data science teaching techniques, methods and materials and with two specific requests and invitations, and covered the following themes:<br>1. Background to the Carpentries2. The history of the Carpentries in Africa3. The African Carpentry Task Force's work in Africa4. My personal use of the Carpentries methods in my professional work at UCT Libraries and Figshare

The Carpentries is an organisation whose primary goal is to teach researchers introductory concep... more The Carpentries is an organisation whose primary goal is to teach researchers introductory concepts for best practices in handling data and basics in coding [1,2]. Volunteer instructors who teach these courses are required to complete a two day curriculum of instructor training and to complete three tasks as part of the checkout process [3]. By February 2018 more than 100 people in Africa had participated in African instructor training workshops but more than half of these participants were not teaching in workshops, either because they did not complete the checkout process or they lacked the opportunity or confidence to teach at workshops. An African Carpentries Task Force [4], established in 2017, focuses on mentoring initiatives to increase the turnover of instructor trainee to active instructor. Mentoring can enhance professional development and teaching in particular [5]. In the first half of 2018, the African Task Force implemented an online lesson supplement which offered six...

Slides from my presentation at International Data Week SciDataCon, Gaborone, 2018.<br>The p... more Slides from my presentation at International Data Week SciDataCon, Gaborone, 2018.<br>The presentation took place in session 244: Sharing lessons on data science teaching techniques, methods and materials and with two specific requests and invitations, and covered the following themes:<br>1. Background to the Carpentries2. The history of the Carpentries in Africa3. The African Carpentry Task Force's work in Africa4. My personal use of the Carpentries methods in my professional work at UCT Libraries and Figshare

Data Carpentry lesson from Ecology curriculum to learn how to use spreadsheet to organize data.

BMC Cancer

Background South Africa (SA) has experienced a rapid transition in the Human Development Index (H... more Background South Africa (SA) has experienced a rapid transition in the Human Development Index (HDI) over the past decade, which had an effect on the incidence and mortality rates of colorectal cancer (CRC). This study aims to provide CRC incidence and mortality trends by population group and sex in SA from 2002 to 2014. Methods Incidence data were extracted from the South African National Cancer Registry and mortality data obtained from Statistics South Africa (STATS SA), for the period 2002 to 2014. Age-standardised incidence rates (ASIR) and age-standardised mortality rates (ASMR) were calculated using the STATS SA mid-year population as the denominator and the Segi world standard population data for standardisation. A Joinpoint regression analysis was computed for the CRC ASIR and ASMR by population group and sex. Results A total of 33,232 incident CRC cases and 26,836 CRC deaths were reported during the study period. Of the CRC cases reported, 54% were males and 46% were female...

Research Square (Research Square), Oct 7, 2020

BMC Cancer, Feb 6, 2021

Background: South Africa (SA) has experienced a rapid transition in the Human Development Index (... more Background: South Africa (SA) has experienced a rapid transition in the Human Development Index (HDI) over the past decade, which had an effect on the incidence and mortality rates of colorectal cancer (CRC). This study aims to provide CRC incidence and mortality trends by population group and sex in SA from 2002 to 2014. Methods: Incidence data were extracted from the South African National Cancer Registry and mortality data obtained from Statistics South Africa (STATS SA), for the period 2002 to 2014. Age-standardised incidence rates (ASIR) and age-standardised mortality rates (ASMR) were calculated using the STATS SA midyear population as the denominator and the Segi world standard population data for standardisation. A Joinpoint regression analysis was computed for the CRC ASIR and ASMR by population group and sex. Results: A total of 33,232 incident CRC cases and 26,836 CRC deaths were reported during the study period. Of the CRC cases reported, 54% were males and 46% were females, and among deaths reported, 47% were males and 53% were females. Overall, there was a 2.5% annual average percentage change (AAPC) increase in ASIR from 2002 to 2014 (95% CI: 0.6-4.5, p-value < 0.001). For ASMR overall, there was 1.3% increase from 2002 to 2014 (95% CI: 0.1-2.6, p-value < 0.001). The ASIR and ASMR among population groups were stable, with the exception of the Black population group. The ASIR increased consistently at 4.3% for black males (95% CI: 1.9-6.7, p-value < 0.001) and 3.4% for black females (95% CI: 1.5-5.3, p-value < 0.001) from 2002 to 2014, respectively. Similarly, ASMR for black males and females increased by 4.2% (95% CI: 2.0-6.5, p-value < 0.001) and 3.4% (, 95%CI: 2.0-4.8, p-value < 0.01) from 2002 to 2014, respectively. Conclusions: The disparities in the CRC incidence and mortality trends may reflect socioeconomic inequalities across different population groups in SA. The rapid increase in CRC trends among the Black population group is concerning and requires further investigation and increased efforts for cancer prevention, early screening and diagnosis, as well as better access to cancer treatment.

Journal of Global Oncology, 2018

Background: South Africa (SA) recently established an urban population-based cancer registry in E... more Background: South Africa (SA) recently established an urban population-based cancer registry in Ekurhuleni metropolitan district in Gauteng Province. The Ekurhuleni Population-Based Cancer Registry (EPBCR) aims to inform cancer policy and comprehensive cancer control programs. The registry covers 3.5 million residents including public/private, rural/urban patients and a mix of the multiethnic SA population. The first complete…

of poster submission for Carpentry Conference 2018 by the African Task Force members.

Slides from my presentation at International Data Week SciDataCon, Gaborone, 2018.<br>The p... more Slides from my presentation at International Data Week SciDataCon, Gaborone, 2018.<br>The presentation took place in session 244: Sharing lessons on data science teaching techniques, methods and materials and with two specific requests and invitations, and covered the following themes:<br>1. Background to the Carpentries2. The history of the Carpentries in Africa3. The African Carpentry Task Force's work in Africa4. My personal use of the Carpentries methods in my professional work at UCT Libraries and Figshare

The Carpentries is an organisation whose primary goal is to teach researchers introductory concep... more The Carpentries is an organisation whose primary goal is to teach researchers introductory concepts for best practices in handling data and basics in coding [1,2]. Volunteer instructors who teach these courses are required to complete a two day curriculum of instructor training and to complete three tasks as part of the checkout process [3]. By February 2018 more than 100 people in Africa had participated in African instructor training workshops but more than half of these participants were not teaching in workshops, either because they did not complete the checkout process or they lacked the opportunity or confidence to teach at workshops. An African Carpentries Task Force [4], established in 2017, focuses on mentoring initiatives to increase the turnover of instructor trainee to active instructor. Mentoring can enhance professional development and teaching in particular [5]. In the first half of 2018, the African Task Force implemented an online lesson supplement which offered six...

Slides from my presentation at International Data Week SciDataCon, Gaborone, 2018.<br>The p... more Slides from my presentation at International Data Week SciDataCon, Gaborone, 2018.<br>The presentation took place in session 244: Sharing lessons on data science teaching techniques, methods and materials and with two specific requests and invitations, and covered the following themes:<br>1. Background to the Carpentries2. The history of the Carpentries in Africa3. The African Carpentry Task Force's work in Africa4. My personal use of the Carpentries methods in my professional work at UCT Libraries and Figshare

Data Carpentry lesson from Ecology curriculum to learn how to use spreadsheet to organize data.

BMC Cancer

Background South Africa (SA) has experienced a rapid transition in the Human Development Index (H... more Background South Africa (SA) has experienced a rapid transition in the Human Development Index (HDI) over the past decade, which had an effect on the incidence and mortality rates of colorectal cancer (CRC). This study aims to provide CRC incidence and mortality trends by population group and sex in SA from 2002 to 2014. Methods Incidence data were extracted from the South African National Cancer Registry and mortality data obtained from Statistics South Africa (STATS SA), for the period 2002 to 2014. Age-standardised incidence rates (ASIR) and age-standardised mortality rates (ASMR) were calculated using the STATS SA mid-year population as the denominator and the Segi world standard population data for standardisation. A Joinpoint regression analysis was computed for the CRC ASIR and ASMR by population group and sex. Results A total of 33,232 incident CRC cases and 26,836 CRC deaths were reported during the study period. Of the CRC cases reported, 54% were males and 46% were female...