Lale Cerrahoğlu - Academia.edu (original) (raw)

Papers by Lale Cerrahoğlu

Meandros medical and dental journal, Jul 1, 2024

Kastamonu Medical Journal, Sep 21, 2023

Aims: Patients with plantar fasciitis modify their gait patterns due to the heel pain. We aimed t... more Aims: Patients with plantar fasciitis modify their gait patterns due to the heel pain. We aimed to investigate whether there was a significant difference in the plantar pressure distribution after pain relief due to successful treatment response in plantar fasciitis. Methods: 49 patients diagnosed with chronic unilateral plantar fasciitis received a 3-week physical therapy intervention and home exercises. Visual analog scale, plantar pressure measurement by pedobarographic assessment and magnetic resonance imaging were performed before and 1 month after the intervention. At the 1-month follow up, participants were divided into 2 groups according to successful or poor response to treatment. The treatment's success criteria was defined as a percentage decrease in heel pain exceeding 60% compared to the baseline, assessed one month after the initiation of treatment. Results: A total of 44 subjects successfully completed the study. In group 1, characterized by successful responders, there were 24 subjects, while group 2, comprising poor responders, included 20 subjects. After treatment in group 1, the dynamic plantar pressure on the medial forefoot showed a significant increase (p = 0.015). However, there was no significant change in plantar pressure in the poor responders. Plantar fascia thickness correlated positively with thumb dynamic pressures (coronal p = 0.03 r = 0.434, sagittal r = 0.451 p = 0.02). Conclusion: The results suggest that fascial thickness and dynamic forefoot plantar pressures may be related. Medial forefoot plantar pressures increased as a result of gait restoration with significant pain reduction in adults.

The main purpose of this study was to compare the values determined in the clinical examination o... more The main purpose of this study was to compare the values determined in the clinical examination of the foot and ankle and the plantar pressure measurements of the foot in athletes who developed an overuse-type disability and in athletes who did not develop overuse-type disability, and was to find factors that might predispose to disability, during the one-year follow-up. 100 licensed football players were included in the study. Presence of joint hypermobility, foot posture assessment, ankle and first metatarsophalangeal (MTP) joint range of motion (ROM) measurements, pedobarographic plantar pressure assessment of foot was carried out. Then, the footballers were followed for 12 months for the development of new foot and ankle overuse injuries and the clinical and pedobarographic data of the footballers with at least one injury were compared with the group without injury. We found asymmetric pressure distribution between the preferred and non-preferred foot in the group who had an injury in the pedobarographic static foot plantar pressure measurements (p = .040). When we compared the ROM values of footballers who had an injury and footballers who did not have an injury, we found a significant limitation in the group that suffered an injury, in the ankle eversion, first MTP joint dorsiflexion and ankle plantarflexion degrees (p = .029, p = .023, p=.044, respectively). These findings suggest that impairments in foot plantar pressure distribution and limitations in ankle All rights reserved. No reuse allowed without permission.

Journal of Clinical and Diagnostic Research, 2017

International Journal of Rheumatology, Aug 27, 2020

Objective. Low-level laser therapy (LLLT) and extracorporeal shock wave therapy (ESWT) is applied... more Objective. Low-level laser therapy (LLLT) and extracorporeal shock wave therapy (ESWT) is applied in the conservative treatment of inflammatory plantar fasciitis, which is also a characteristic feature of spondyloarthritis (SpA) (Gill, 1997 and Roxas, 2005). We determined and compared the effectiveness of LLLT and ESWT using magnetic resonance imaging (MRI). Methods. This study is a prospective, randomized, comparative, single-blind clinical study. Voluntarily followed 40 patients with the diagnosis of SpA and having pain at the heels at least for 6 months. Patients were divided randomly into two treatment groups. One group undertook 14 sessions of infrared Ga-Al-As LLLT, and the other group undertook 3 sessions ESWT. Feet functions of the patients were evaluated by American Orthopaedic Foot and Ankle Society (AOFAS) and Roles and Maudsley Scoring; VAS was evaluated for foot pain and function. In clinical assessment, disease activity was carried out by applying the BASDAI, the functional assessment was evaluated through the BASFI, and the patient quality of life was evaluated through the ASQoL; enthesitis was scored according to MASES assessment, performed before and at 1 month after treatment. The thickness of the plantar fascia was measured with MRI before and 1 month after treatment. Results. Compared with the pretherapy, progress in the feet function by AOFAS and Roles-Maudsley scoring and decrease in VAS levels were statistically significant in both groups (p < 0:001). Only the VAS exercise score was superior to LLLT (p < 0:05). The thickness of the plantar fascia had decreased significantly on MRI in all two groups. Conclusion. The treatment of plantar fasciitis with LLLT and ESWT was more successful in pain improvement and functional outcomes with the dose, frequency, and duration used in our study.

Scandinavian Journal of Rheumatology, 1998

Rheumatoid arthritis (RA) is a heterogeneous disorder with a spectrum of clinical severity rangin... more Rheumatoid arthritis (RA) is a heterogeneous disorder with a spectrum of clinical severity ranging from mild arthritis to a crippling joint disease with involvement of internal organs. Carnitine is essential for muscle energy production and is required for the transport of long chain fatty acids and the acyl coenzyme A derivatives across the inner mitochondrial membrane. The levels of malondialdehyde (MDA), an index of lipid peroxidation, and the antioxidants copper-zinc superoxide dismutase (CuZnSOD), glutathione (GSH), ceruloplasmin (CP), catalase (CAT), and carnitine were assessed in 42 patients with RA and 24 control subjects. While plasma carnitine and erythrocyte CuZnSOD levels were significantly lower in the patients with RA compared with the control group (p<0.01 and p<0.001, respectively), the CAT level was not different from controls (p>0.05). Plasma MDA, CP, and erythrocyte GSH levels were significantly higher than in the control group (p<0.001, p<0.001 and p<0.01, respectively). MDA levels showed a positive correlation with CP and GSH levels (r=0.716, p<0.001 and r=0.492, p<0.01, respectively). However, MDA, GSH, and CP demonstrated a negative correlation with carnitine (r=-0.719, p<0.001; r=-0.559, p<0.01, and r=-0.635, p<0.001, respectively) in the patient group but not in controls. There was also a significant positive correlation between CP and GSH levels (r=0.561, p<0.01). However, neither CuZnSOD nor CAT levels demonstrated correlation withcarnitine, MDA, GSH, or CP levels. It was interesting that CAT activity was not altered and CuZnSOD activity decreased when compared with the control group. These results suggest that while CP, MDA and GSH levels increased, carnitine and CuZnSOD levels decreased, but CAT activity was unchanged.

Turkiye Klinikleri Physical Medicine Rehabilitation - Special Topics, 2009

Journal of the American Podiatric Medical Association, May 1, 2016

Background: We aimed to investigate whether a home exercise for self-care program that consists o... more Background: We aimed to investigate whether a home exercise for self-care program that consists of range of motion (ROM), stretching, and strengthening exercises could improve ROM for foot joints and plantar pressure distribution during walking in diabetic patients to prevent diabetic foot complications. Methods: Seventy-six diabetic patients were recruited (38 with neuropathy and 38 without neuropathy). Neuropathy and nonneuropathy groups were randomly divided into a home exercise group (n ¼ 19) and a control group (n ¼ 19). Exercise groups performed their own respective training programs for 4 weeks, whereas no training was done in the control group. Total contact area and plantar pressure under six foot areas before and after the exercise program were measured. Ankle and first metatarsophalangeal joint ROM were measured before and after the exercise program. Results: In the exercise group, there were significant improvements in ROM for the ankle and first metatarsophalangeal joints (P , .001); static pedobarographic values showed significant reduction in right forefoot-medial pressure (P ¼ .010); and significant decreases were seen in dynamic pedobarographic values of peak plantar pressure at the left forefoot medial (P ¼ .007), right forefoot lateral (P ¼ .018), left midfoot (P , .001), and right hindfoot (P ¼ .021) after exercise. No significant positive or negative correlation was found between the neuropathy and nonneuropathy groups (P. .05). Conclusions: A home exercise program could be an effective preventive method for improving ROM for foot joints and plantar pressure distribution in diabetic patients independent of the presence of neuropathy.

Türk Osteoporoz Dergisi, 2002

The present study was performed to assess the relation between dietary calcium intake and bone mi... more The present study was performed to assess the relation between dietary calcium intake and bone mineral density in postmenopausal women. For this purpose 87 postmenopausal who had not got any treatment that interacts with bone metabolism previously were enrolled in the study. The standard questionnaire was filled out by a physician to determine the daily calcium intake for each patient. Bone mineral density T and Z scores of L1-L4 region, L3 lateral, femur neck, trochanter and Ward's triangle were assessed. Spearman's nonparametric rank correlation coefficient was used to evaluate the relation between two quantitative variables. In conclusion; only a close relationship was observed between the dietary calcium intake and the bone mass index and Z-score in L1-L4 region (r= 0.521, p=0.015; r=0.482, p=0.027, respectively). No relationship was found between the bone mass index Z and T-score and the dietary calcium intake in remaining four regions.

Spor ve Performans Araştırmaları Dergisi, 2014

Bu araştırmanın amacı; beden eğitimi ve spor yüksekokulu (BESYO) öğrencilerinin bilişötesi öğrenm... more Bu araştırmanın amacı; beden eğitimi ve spor yüksekokulu (BESYO) öğrencilerinin bilişötesi öğrenme stratejileri ve akademik öz-yeterlik algılarını bazı değişkenlere göre incelemek ve aralarındaki ilişkiyi belirlemektir. Betimsel araştırma modelindeki araştırmanın çalışma grubunu, Karadeniz Teknik Üniversitesi ve Erzincan Üniversitesinin beden eğitimi ve spor yüksekokulunda öğrenim gören 143'ü kadın ve 205'i erkek 348 öğrenci oluşturmaktadır. Araştırma kapsamındaki öğrencilerin yaş ortalamaları 21,84 ± 2,49'dur. Araştırmada veri toplama aracı olarak Bilişötesi Öğrenme Stratejileri Ölçeği ve Akademik Öz-Yeterlik Ölçeği kullanılmıştır. Veriler, betimsel istatistik yöntemler, t-testi, ANOVA ve korelasyon testi kullanılarak analiz edilmiştir. Araştırmadan elde edilen bulgular doğrultusunda, çalışma grubunda yer alan öğrencilerin bilişötesi öğrenme strateji düzeylerinin orta seviyede, akademik öz-yeterlik algılarının da orta seviyenin üzerinde olduğu görülmektedir. Araştırma sonucunda, bilişötesi öğrenme stratejilerinin cinsiyet değişkenine göre erkek öğrencilerin lehine farklılaştığı görülürken bölüm ve sınıf değişkenine göre anlamlı bir farklılık tespit edilmemiştir. Öğrencilerin akademik öz-yeterlik algıları ise cinsiyet, bölüm ve sınıf değişkenine göre anlamlı bir şekilde farklılaşmamaktadır. Diğer taraftan araştırma sonuçları, BESYO öğrencilerinin bilişötesi öğrenme stratejileri, akademik öz-yeterlikleri ve akademik başarıları arasında pozitif yönde korelasyonlar olduğunu göstermektedir.

DergiPark (Istanbul University), Feb 19, 2010

Dejeneratif artritlerde intraartiküler olarak uygulanan hyaluronik asit (HA) ve metil prednisolon... more Dejeneratif artritlerde intraartiküler olarak uygulanan hyaluronik asit (HA) ve metil prednisolon asetat (MPA) tedavilerinin etkilerini araştınnak için deneysel bir çalışma yapıldı. 40 adet erkek ratın sag arka diz eklemleri içine 0.2 ml %1 'lik fonnalin verilerek deneysel artrit oluşturuldu. İlaç verilmesinden bir hafta sonra LO rat öldürölerek artritin oluştuğu histopatolojik olarak belirlendi. Kalan 30 rat 3 gruba aynldı. Birinci gruba 0,05 ml intraartiküler HA (HA grubu), ikinci gruba 0.05 ml intra.artiktiler MPA (MPA grubu) verildi. Üçüncü gruba ise intraartiküler 0.05 ml serum fizyolojik verilerek kontrol grubu oluşturuldu. Tedaviler artrit oluşturulduktan sonra 7. Gün, 14, Gün ve 21. gün uygulandı. Uygulanan bu tedavilerin bitiminden 15 gün sonra ratlar öldürüldü ve alınan örnekler, histopatolojik olarak: incelendi. Yapılan incelemede; MPA grubunda kıkırdak iyileşmesi açısından kontrol grubuna göre anlamlı fark bulunamadı (p>O.05). HA gruburida ise kıkırdak iyileşmesi MPA ve kontrol grubuna göre anlamlı olarak yüksek bulundu (p<o.05). İntraartiküler artrit tedavisinde kılcırdak: dokusu üzerine olumlu etkilerirıden dolayı HA'in MPA'a göre daha yararlı oldugu sonucuna varıldı. Anahtar kelimeler: Deneysel artrit, lcıkırdak:, hyaluronik asit, metil prednisolon asetat. SUMMARY EFFECTS OF INTRAARTICULAR HYALURONlC ACID AND METHYL PREDNlSOLONE ACETATE ON CARTaAGE IN A MODEL OF EXPERIMENTAL ARTURlTIS IN RATS This experimental study was perfonned to detennine the effects of intraarticular hyaluronic acid (HA) and methyl prednisolone acetate (MPA) in degenerative osıeoarthritis, 0.2 ml 1% fonnaline were injected to the posterior right knee joints of 40 male rats. One week after the injeetions, LO rats were kiIled and arthritis was detennined histopathologically. The remained 30 rats were divided to three groups. First group received intraarticularly 0.05 ml HA (HA group), second group 0.05 ml MPA (MPA group) and third group 0.05 ml saline as contrals. The injections were perfonned at 7., 14. and 21. days after the arthritis. 15 days after the end of these treatments, rats were killed and sections were examined histopathologically.

Journal of Foot & Ankle Surgery, Jul 1, 2017

Meandros Medical and Dental Journal, Dec 9, 2020

Femoroacetabular impingement (FAI) is an abnormal contact of the acetabulum with the femur, parti... more Femoroacetabular impingement (FAI) is an abnormal contact of the acetabulum with the femur, particularly during flexion and hip rotation, caused by anatomical abnormalities in the femur head and acetabulum, and may result in labral and cartilage damage in the hips. According to the graphical features of the pelvis AP, three types of FAI were defined: cam, pincer and, mix type. Moreover, the mix is the most common type, where typically patients complain of pain in the hip and groin. With symptomatic treatment in the initial phase, the patient's complaints are relieved. However, if the severity of the impingement progresses, the patient may be referred for surgery. Arthroscopic or open surgery corrects the deformity of the femur head and acetabulum.

Journal of Physical Therapy Science, 2001

Objective: Efficacy of collar treatment on clinical symptoms and vertebral blood flow was examine... more Objective: Efficacy of collar treatment on clinical symptoms and vertebral blood flow was examined in 23 patients with cervical spondylartrosis complaining of vertigo. Methods: In pretreatment and posttreatment periods, the following parameters were studied: 1) frequency of cervicocephalic symptoms, 2) influence of severity of the vertigo on daily life activity, 3) range of active cervical joint movement, 4) pain in cervical palpation, 5) vertebral blood flow by Doppler ultrasonography, and audiologic and brainstem auditory evoked potential (BAEP) examinations for hearing. Results: Following 1 month of collar treatment, vertigo and amnesia were the only symptoms which were significantly relieved (p=0.01, p=0.03). In addition, the severity of the symptoms were noticeably decreased. Range of cervical joint movements on extention, lateral flexion and rotation were increased. Cervical palpation was reduced and the pain was less. However, no change was observed in vertebral blood flow, audiometric and BAEP examinations. Conclusion: It was concluded that vertigo in cervical spondylartrosis was not a consequence of vertebrobasillar insufficiency. Hypertonicity in cervical muscles was the primary reason for vertigo in these patients.

Meandros Medical and Dental Journal, May 6, 2020

Familial Mediterranean Fever (FMF) is the most common Periodic Fever syndrome characterized by at... more Familial Mediterranean Fever (FMF) is the most common Periodic Fever syndrome characterized by attacks like serositis and fever. FMF is an autosomal recessive disease caused by MEFV gene mutations which located on 16p13.3. Spondyloarthropathy (SpA) is a chronic rheumatic disease characterized by inflammation in axial and peripheral joints with enthesitis and extraartricular involvements. One of the major criteria of SpA is sacroiliitis that can be described rarely in FMF patients. M694V mutation has been frequently seen mutation in FMF patients; also it has been associated with SpA. In this article, we present a case of a patient with heterozygous M694V mutation FMF and SpA combination.

Turkiye Klinikleri Physical Medicine Rehabilitation - Special Topics, 2016

The Journal of Sports Medicine and Physical Fitness

BACKGROUND Foot and ankle are some of the most frequently injured places in football players'... more BACKGROUND Foot and ankle are some of the most frequently injured places in football players' bodies. Overuse injuries have an insidious onset and can restrain athletes from sports temporary or even permanently. This study aimed to investigate the relationship between the clinical evaluation of the foot and ankle and findings obtained from foot plantar pressure measurements with the development of overuse injury, during the one-year follow-up. METHODS 100 licensed football players were included in the study. Presence of joint hypermobility, foot posture assessment, ankle and first metatarsophalangeal joint range of motion measurements, pedobarographic plantar pressure assessment of foot was carried out. Then, the footballers were followed for 12 months for the development of new foot and ankle overuse injuries, and the clinical and pedobarographic data of the footballers with at least one injury were compared with the group without injury. RESULTS We found asymmetric pressure distribution between the preferred and non-preferred foot in the group who had an injury in the pedobarographic static foot plantar pressure measurements (p = .040). A statistically significant limitation was found in the ankle eversion, first metatarsophalangeal joint dorsiflexion and ankle plantar flexion degrees in the injured group compared to the uninjured group (p = .029, p = .023, p=.044, respectively). CONCLUSIONS These findings suggest that impairments in foot plantar pressure distribution and limitations in ankle and foot joint range of motion may be risk factors for the development of foot and ankle overuse injury.

Archives of Rheumatology

Objectives: The purpose of the study was to contribute further to this debated topic by investiga... more Objectives: The purpose of the study was to contribute further to this debated topic by investigating the correlation of magnetic resonance imaging (MRI) findings with the clinical picture in lumbar spondylosis patients. Patients and methods: This multicenter retrospective study (as part of the epidemiological project of the TLAR-OASG [Turkish League Against Rheumatism-Osteoarthritis Study Group]) included 514 patients (101 males, 413 females; mean age: 63.6±10.8 years; range, 40 to 85 years) who were diagnosed as lumbar spondylosis by clinical examination and direct X-ray between December 2016 and June 2018. Demographic characteristics of patients, Visual Analog Scale for pain, presence of radiating pain, Roland-Morris disability questionnaire, straight leg raise test, deep tendon reflexes, neurogenic intermittent claudication symptoms, any decrease of muscle strength, and abnormality of sensation were recorded. Lumbar MRI findings of the patients were recorded as positive or negat...

Aim: BONCURE (Bonviva for Current Bisphosphonate Users Regional European Trial), aimed to evaluat... more Aim: BONCURE (Bonviva for Current Bisphosphonate Users Regional European Trial), aimed to evaluate patient preference with monthly ibandronate in women with postmenopausal osteoporosis who previously received daily or weekly alendronate or risendronate. Materials and Methods: This prospective, open-label study consisted of two sequential stages, Part A (screening) and Part B (treatment). Patients enrolled into Part A completed the Candidate Identification Questionnaire (CIQ). In Part B, after completing the Osteoporosis Patient Satisfaction Questionnaire (OPSAT-Q), patients received monthly oral ibandronate 150 mg for 6 months. Following treatment, patients completed the OPSAT-Q and Preference Questionnaire. Results: A total of 223 patients (mean age, 63.7±9.51 years) were enrolled in Part A from Turkey. Among them, 103 (46.2%) answered "YES" to at leastone CIQ question. The mean composite OPSAT-Q domain scores increased for convenience (mean change, 15.3±17.7 points), qua...