Wojciech Lasek - Academia.edu (original) (raw)
Papers by Wojciech Lasek
Nowadays, several screening strategies are available to prevent cervical cancer, but inadequate r... more Nowadays, several screening strategies are available to prevent cervical cancer, but inadequate resources, sociocultural barriers, and sampling issues impede their success in low-income countries. To overcome these issues, this study aimed to evaluate the performance of human papillomavirus (HPV) testing from dried urine spots (DUS). Eighty-eight urine samples (including 56 HPV DNA positive specimens) were spotted on filter paper, dried, and stored in paper-bags. HPV DNA was detected from the DUS after 1 week and 4 weeks of storage using a polymerase chain reaction (PCR) assay. The sensitivity, specificity, and concordance of the DUS-based HPV test were evaluated by comparing the results with those of HPV testing on fresh urine samples as the gold standard. The sensitivity of the test was 98.21% (95% CI: 90.56-99.68) for DUS stored for 1 week and 96.42% (95% CI: 87.88-99.01) for DUS stored for 4 weeks. The specificity was 100% (95% CI: 89.28-100) at both time points. The concordance between DUS and fresh urine HPV testing was "almost perfect" using the statistic. These preliminary data suggest that a DUS-based assay could bypass sociocultural barriers and sampling issues and therefore could be a suitable, effective tool for epidemiological surveillance and screening programs, especially in low-income countries.
The dry friction and wear characteristics of rare earth/MoSi2 composite against 45 steel under di... more The dry friction and wear characteristics of rare earth/MoSi2 composite against 45 steel under different loads were investigated by using an M-200 type friction and wear tester. SEM and XRD were used to analyze the morphology of the friction surface and the phase of worn piece in order to reveal the wear mechanism of rare-earth/MoSi2 composite. Results show that the relationships of friction coefficient, μ, or wear rate, W, of MoSi2 and RE/MoSi2 composite to loads,p, can be fitted well with the following function: μ (or W) = a + bp + cp2 + dp3 + ep4, where a, b, c, d and e are fitting constants depending on materials and confidence. MoSi2 and rare-earth/MoSi2 composite have excellent wear resis-tance. When load is in the range of 80 - 120 N, the wear rate of RE/MoSi2 composite is lower than that of MoSi2 materialby about 65 %. The main wear mechanism of rare-earth/MoSi2 composite is adhesive wear.
Icho Pan Sygn B Org 327 11, 2011
Journal of Physical Organic Chemistry, 1993
A new rationalization of some phenomena in the phase-transfer catalysed processes promoted by con... more A new rationalization of some phenomena in the phase-transfer catalysed processes promoted by concentrated aqueous alkali solutions, such as alkylations and &eliminations, is proposed. It is predicted on the basis of adsorption theory and subsequently evidenced experimentally that the size of the interfacial area, controlled by the rate of stirring, affects the position of the extraction equilibrium of various anions with quaternary ammonium cations supplied by the phase-transfer catalysts.
Central European Journal of Chemistry, 2013
The present work focused on the qualitative and quantitative analysis of Cr detoxification strate... more The present work focused on the qualitative and quantitative analysis of Cr detoxification strategy of aquatic cosmopolitan plant Callitriche cophocarpa. This plant species has just been described in the context of its unusual accumulation potential of Cr. The emphasis of the work was placed on the redox reaction Cr(VI)→Cr(III) which is considered to be remediation mechanism of highly reactive and mobile Cr(VI) ions. Plants were immersed for 5 days in 1 mM of Cr(VI) (potassium dichromate) or 1 mM of Cr(III) (chromium sulphate) solutions in semi-natural conditions. Cr was effectively removed from the solution up to the extent of ca.58% or 35% of the starting amount, in the case of Cr(III) and Cr(VI), respectively. No plant-induced Cr(VI) reduction accompanying Cr accumulation was observed in Cr(VI) solutions except from the apparent one, noticed at the fourth day of incubation. On the contrary to these results, according to the method of electron paramagnetic resonance spectroscopy (...
Synthesis, 1993
Phenylacetonitrile and 2-phenylalkanenitriles react under phase transfer catalysis conditions wit... more Phenylacetonitrile and 2-phenylalkanenitriles react under phase transfer catalysis conditions with 2-propenylanisoles containing electron-withdrawing substituents (or their corresponding precursors, 2-allylanisoles) via the Michael addition pathway to give substituted 4-aryl-2-phenylbutyronitriles
Journal of Environmental Management
The present study focused on the use of the dry mass of the macrophyte Callitriche cophocarpa as ... more The present study focused on the use of the dry mass of the macrophyte Callitriche cophocarpa as an effective biosorbent for chromium removal from concentrated solutions, typical for industrial effluents. In order to evaluate the usability of C. cophocarpa as the Cr(III) sorbent, its detailed physicochemical characterization has been performed as well as the preliminary adsorption studies. The biosorbent was characterized by specific surface area (SSA), porosity, total organic carbon (TOC), inorganic content as well as the cation exchange capacity (CEC), dominant exchangeable cations and anion exchange capacity (AEC), point of zero charge (pHpzc) and buffering capacity. The effect of the initial chromium concentration, solution pH and co-existing anions on the sorption effectiveness have been investigated. Based on theoretical isotherm models, the maximum adsorption capacity of the dry C. cophocarpa has been determined as 77.1 mg Cr(III)/g. Finally, the strength of Cr-binding onto the plant biomass has been evaluated using the BCR extraction method, stating that chromium was strongly and - under environmental conditions - irreversibly bound to the plant biomass.
Nowadays, several screening strategies are available to prevent cervical cancer, but inadequate r... more Nowadays, several screening strategies are available to prevent cervical cancer, but inadequate resources, sociocultural barriers, and sampling issues impede their success in low-income countries. To overcome these issues, this study aimed to evaluate the performance of human papillomavirus (HPV) testing from dried urine spots (DUS). Eighty-eight urine samples (including 56 HPV DNA positive specimens) were spotted on filter paper, dried, and stored in paper-bags. HPV DNA was detected from the DUS after 1 week and 4 weeks of storage using a polymerase chain reaction (PCR) assay. The sensitivity, specificity, and concordance of the DUS-based HPV test were evaluated by comparing the results with those of HPV testing on fresh urine samples as the gold standard. The sensitivity of the test was 98.21% (95% CI: 90.56-99.68) for DUS stored for 1 week and 96.42% (95% CI: 87.88-99.01) for DUS stored for 4 weeks. The specificity was 100% (95% CI: 89.28-100) at both time points. The concordance between DUS and fresh urine HPV testing was "almost perfect" using the statistic. These preliminary data suggest that a DUS-based assay could bypass sociocultural barriers and sampling issues and therefore could be a suitable, effective tool for epidemiological surveillance and screening programs, especially in low-income countries.
The dry friction and wear characteristics of rare earth/MoSi2 composite against 45 steel under di... more The dry friction and wear characteristics of rare earth/MoSi2 composite against 45 steel under different loads were investigated by using an M-200 type friction and wear tester. SEM and XRD were used to analyze the morphology of the friction surface and the phase of worn piece in order to reveal the wear mechanism of rare-earth/MoSi2 composite. Results show that the relationships of friction coefficient, μ, or wear rate, W, of MoSi2 and RE/MoSi2 composite to loads,p, can be fitted well with the following function: μ (or W) = a + bp + cp2 + dp3 + ep4, where a, b, c, d and e are fitting constants depending on materials and confidence. MoSi2 and rare-earth/MoSi2 composite have excellent wear resis-tance. When load is in the range of 80 - 120 N, the wear rate of RE/MoSi2 composite is lower than that of MoSi2 materialby about 65 %. The main wear mechanism of rare-earth/MoSi2 composite is adhesive wear.
Icho Pan Sygn B Org 327 11, 2011
Journal of Physical Organic Chemistry, 1993
A new rationalization of some phenomena in the phase-transfer catalysed processes promoted by con... more A new rationalization of some phenomena in the phase-transfer catalysed processes promoted by concentrated aqueous alkali solutions, such as alkylations and &eliminations, is proposed. It is predicted on the basis of adsorption theory and subsequently evidenced experimentally that the size of the interfacial area, controlled by the rate of stirring, affects the position of the extraction equilibrium of various anions with quaternary ammonium cations supplied by the phase-transfer catalysts.
Central European Journal of Chemistry, 2013
The present work focused on the qualitative and quantitative analysis of Cr detoxification strate... more The present work focused on the qualitative and quantitative analysis of Cr detoxification strategy of aquatic cosmopolitan plant Callitriche cophocarpa. This plant species has just been described in the context of its unusual accumulation potential of Cr. The emphasis of the work was placed on the redox reaction Cr(VI)→Cr(III) which is considered to be remediation mechanism of highly reactive and mobile Cr(VI) ions. Plants were immersed for 5 days in 1 mM of Cr(VI) (potassium dichromate) or 1 mM of Cr(III) (chromium sulphate) solutions in semi-natural conditions. Cr was effectively removed from the solution up to the extent of ca.58% or 35% of the starting amount, in the case of Cr(III) and Cr(VI), respectively. No plant-induced Cr(VI) reduction accompanying Cr accumulation was observed in Cr(VI) solutions except from the apparent one, noticed at the fourth day of incubation. On the contrary to these results, according to the method of electron paramagnetic resonance spectroscopy (...
Synthesis, 1993
Phenylacetonitrile and 2-phenylalkanenitriles react under phase transfer catalysis conditions wit... more Phenylacetonitrile and 2-phenylalkanenitriles react under phase transfer catalysis conditions with 2-propenylanisoles containing electron-withdrawing substituents (or their corresponding precursors, 2-allylanisoles) via the Michael addition pathway to give substituted 4-aryl-2-phenylbutyronitriles
Journal of Environmental Management
The present study focused on the use of the dry mass of the macrophyte Callitriche cophocarpa as ... more The present study focused on the use of the dry mass of the macrophyte Callitriche cophocarpa as an effective biosorbent for chromium removal from concentrated solutions, typical for industrial effluents. In order to evaluate the usability of C. cophocarpa as the Cr(III) sorbent, its detailed physicochemical characterization has been performed as well as the preliminary adsorption studies. The biosorbent was characterized by specific surface area (SSA), porosity, total organic carbon (TOC), inorganic content as well as the cation exchange capacity (CEC), dominant exchangeable cations and anion exchange capacity (AEC), point of zero charge (pHpzc) and buffering capacity. The effect of the initial chromium concentration, solution pH and co-existing anions on the sorption effectiveness have been investigated. Based on theoretical isotherm models, the maximum adsorption capacity of the dry C. cophocarpa has been determined as 77.1 mg Cr(III)/g. Finally, the strength of Cr-binding onto the plant biomass has been evaluated using the BCR extraction method, stating that chromium was strongly and - under environmental conditions - irreversibly bound to the plant biomass.