Laurie Goodrich - Academia.edu (original) (raw)

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Papers by Laurie Goodrich

Research paper thumbnail of Biochemical and Biomechanical Properties of Lesion and Adjacent Articular Cartilage After Chondral Defect Repair in an Equine Model

American Journal of Sports Medicine, 2005

Articular cartilage defects, which may occur secondary to trauma or osteochondritis dissecans, co... more Articular cartilage defects, which may occur secondary to trauma or osteochondritis dissecans, continue to be a significant challenge for the orthopaedic surgeon. Symptomatic chondral defects often lead to pain, swelling, and disability in affected patients. These sequelae are thought to be secondary not only to the poor repair response within the cartilage defect itself but also to the deleterious effects of the defect on the surrounding cartilage, which may predispose patients to developing osteoarthritis. Previous studies have shown that injury leads to morphologic changes and matrix degradation not only in the directly injured area but also in the surrounding cartilage Background: Chondral defects may lead to degradative changes in the surrounding cartilage, predisposing patients to developing osteoarthritis.

Research paper thumbnail of Biochemical and Biomechanical Properties of Lesion and Adjacent Articular Cartilage After Chondral Defect Repair in an Equine Model

American Journal of Sports Medicine, 2005

Articular cartilage defects, which may occur secondary to trauma or osteochondritis dissecans, co... more Articular cartilage defects, which may occur secondary to trauma or osteochondritis dissecans, continue to be a significant challenge for the orthopaedic surgeon. Symptomatic chondral defects often lead to pain, swelling, and disability in affected patients. These sequelae are thought to be secondary not only to the poor repair response within the cartilage defect itself but also to the deleterious effects of the defect on the surrounding cartilage, which may predispose patients to developing osteoarthritis. Previous studies have shown that injury leads to morphologic changes and matrix degradation not only in the directly injured area but also in the surrounding cartilage Background: Chondral defects may lead to degradative changes in the surrounding cartilage, predisposing patients to developing osteoarthritis.

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