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Papers by Lekshmi Gangadhar

This comprehensive study on triple-negative breast cancer (TNBC) demonstrates a pioneering approa... more This comprehensive study on triple-negative breast cancer (TNBC) demonstrates a pioneering approach by exploring metabolic pathways, specifically focusing on the alkaline glucose isomer, glucosodiene, as a potential therapy. The case report provides a detailed account of a 42-year-old TNBC patient with lymph node metastasis, showcasing the efficacy of glucosodiene treatment in restoring normal vital functions and suppressing cellular activity. Overall, the study contributes valuable insights for developing individualized treatment plans and establishing robust follow-up protocols for TNBC patients.

CRC Press eBooks, Apr 5, 2023

Advances in Materials Science and Engineering

Water pollution is a global issue because of potentially lethal toxins. Polymeric nanomaterials a... more Water pollution is a global issue because of potentially lethal toxins. Polymeric nanomaterials are making their way into water treatment processes and are being utilized to efficiently remove a variety of pollutants. Polymeric nanomaterials are a popular option for a solution because they have a high adsorption capacity and a high surface charge. Nanocomposites have recently come to the attention of those working in the field of water treatment in order to more effectively remove contaminants. Polymeric composites are based on biopolymers and are being developed. These all quickly reached the industrial standards because of their low impact on the natural world. Chitosan is one of the biopolymers that are used extensively. Moreover, it is one of the most highly preferred biopolymers. It is simple to scale up and is readily available. The incorporation of nanomaterials into the biopolymer enables better control over the shape, size, and morphology of the particle, as well as an incr...

Biogenic Sustainable Nanotechnology

International Journal of Molecular Sciences, 2020

Scaffolds are important to tissue regeneration and engineering because they can sustain the conti... more Scaffolds are important to tissue regeneration and engineering because they can sustain the continuous release of various cell types and provide a location where new bone-forming cells can attach and propagate. Scaffolds produced from diverse processes have been studied and analyzed in recent decades. They are structurally efficient for improving cell affinity and synthetic and mechanical strength. Carbon nanotubes are spongy nanoparticles with high strength and thermal inertness, and they have been used as filler particles in the manufacturing industry to increase the performance of scaffold particles. The regeneration of tissue and organs requires a significant level of spatial and temporal control over physiological processes, as well as experiments in actual environments. This has led to an upsurge in the use of nanoparticle-based tissue scaffolds with numerous cell types for contrast imaging and managing scaffold characteristics. In this review, we emphasize the usage of carbon...

One of the potential applications of nanotechnology is that they provide promising improvements i... more One of the potential applications of nanotechnology is that they provide promising improvements in the field of sensor technology. In search for better electrochemical performance the use of nanomaterials in place of conventional one (micro crystalline transition metal oxides) has emerged as excellent alternative. In this work, ZnO nanowires were synthesized by wet chemical method. The precursors used for this experiment involves zinc sulphate, ammonium hydroxide, sodium hydroxide. The precursor's acts as both ...

Biogenic Sustainable Nanotechnology

This goal of study is to enquire how tourism correlates with a country’s image as indicated in re... more This goal of study is to enquire how tourism correlates with a country’s image as indicated in recent marketing literature, a majority of tourists will rely one’s image of a country rather than the travel itself or one’s economic benefit from the travel. The purpose of this study is to verify the effect that a country’s image has upon tourist attitudes and behavioral intentions. In this aim, the targets of the survey were Chinese tourists which comprise a large majority of Jeju foreign tourists as per the results released by the Korea Tourism Organization and Jeju Tourism Association in 2009. The results of the study indicate that, as long as there is an interdependent and complementary relationship among the country image, the tourist destination attitude and tourist behavioral intentions, cooperation and diversified efforts are required to induce positive attitudes and behavioral intentions of tourists. As tourist destination attitudes are very important factors for tourist behavi...

In recent years, nanotechnology has developed to a stage that makes it possible to produce, chara... more In recent years, nanotechnology has developed to a stage that makes it possible to produce, characterize and specifically tailor the structural and functional properties of nanoparticles for clinical applications. Cartilage damage is typically associated with work and athletic injuries, and commonly occurs in conjunction with ACL tears and other ligament problems. Cartilage does not grow back, so treatments to regenerate the tissue are critical. The new biomedical therapy involving nanotechnology promotes the growth of new, stronger cartilage to aid in the treatment of joint injuries. This review article analyses the various technologies available for the diagnostic and therapeutic potentials of nanotechnology towards chronic arthritis.

Nanotechnology and nanoscience are considered to be the “hot” research areas of the decade and ha... more Nanotechnology and nanoscience are considered to be the “hot” research areas of the decade and have attracted the attention of many researchers. The discovery of sophisticated nanomaterial characterization techniques has accelerated their research. The application of numerous morphological and physicochemical characterization tools for effectively resolving their shape, charge, size, surface coatings, and functional groups has improved the human understanding of the nanoworld. Furthermore, these techniques are vital to resolve the tolerable variation in surface chemistry without altering the material characteristics. This chapter sheds light on the most commonly used physicochemical characterization tools, to study nanoscale materials for biofuel production. The most commonly used techniques are reported in this chapter.

11 Published By: Blue Eyes Intelligence Engineering & Sciences Publication Retrieval Number:F1003... more 11 Published By: Blue Eyes Intelligence Engineering & Sciences Publication Retrieval Number:F10030476S519/19 ©BEIESP Abstract: The solar energy is the potential renewable green energy supply while considering the provision of sunlight in abundance and requirement for clean and renewable source of energy. The quantum dots sensitized solar cells (QDSC) provide an alternative perception to current photovoltaic devices. Quantum dots are colloidal nanocrystalline semiconductors possessing distinctive properties owing to quantum confinement effects. Quantum dots synthesis is based on an aqueous medium involving cadmium sulphate, zinc acetate, thiourea and ammonium hydroxide and assemble these quantum dots with nanoporous TiO2 films for quantum dots-sensitized solar cell applications. Titanium dioxide nanowires (TNW) were fabricated by a wet chemical method. Physical and chemical properties of the formed nanoparticles were differentiated using field emission scanning electron microscope (F...

In our work, electrical and optoelectronic properties of P-type porous silicon (PSi) prepared usi... more In our work, electrical and optoelectronic properties of P-type porous silicon (PSi) prepared using chemical etching method are studied, specifically capacitancevoltage (C-V), current-voltage (I-V), responsivity and detectivity severally are analyzed. It had been found that electrical characteristics of porous Si samples measured in dark (Id) and below illumination (IPh) will be fitted well by the equations of thermal emission. From this point of view, Schottky barrier height (ɸB) and ideality factor (n) of made-up photodetectors were calculated. The I-V characteristics of dark and illuminations that passes current through the PSi layer reduced by increasing the etching current, as a result of increasing the electrical resistance of PSi layer and therefore the optimum value of ideality factor is (2.7), whereas from C-V characteristic determined that in-built potential accumulated with increasing etching current. The results show that there are clear results for better performance of...

Due to the capacity to moderate metals to their nanometer size, nanobiotechnology is gaining enor... more Due to the capacity to moderate metals to their nanometer size, nanobiotechnology is gaining enormous popularity in this period, which effectively changes its chemical, physical and optical properties. Recent progress in nanoscience and technology has also managed to the growth of new nanomaterials (NMs), eventually increasing toxic and potential health effects. There has been growing attention in evolving eco-friendly methods for metal nanoparticles (NPs) synthesis. The main purpose of the study is to reduce the harmful influences of synthetic processes, associated substances alongside other derivatives. The use of diverse biomaterials (BMs) for NP synthesis is examined as a promising method in green nanotechnology. However, most of the techniques currently available are costly; utilizing the natural properties includes plants, bacteria, fungi and algae to manufacture low-cost, non-toxic and energy-efficient metallic NPs that are environmentally friendly. Besides, biologically synt...

SN Applied Sciences

In this present work, we described a bio-reduction method for the generation of silver nanopartic... more In this present work, we described a bio-reduction method for the generation of silver nanoparticles (AgNPs) using aqueous leaf extract of Micrargeria wightii (M. wightii), which is a gifted alternative to other physicochemical routes. The prepared AgNPs were characterized by UV–visible spectroscopy (UV–vis), Fourier Transform Infrared Spectroscopy (FT-IR), X-ray diffraction (X-RD), Transmission Electron Microscopy (TEM) with EDX and Dynamic light scattering (DLS). UV–visible spectrum showed a characteristic absorption peak at 440 nm of synthesized AgNPs. FT-IR analysis confirmed the existence of plant metabolites, which are responsible for the reduction of Ag (I) ions into Ag (0) NPs. X-RD pattern studies confirm the presence of the pure face-centered cubiccrystalline nature of Ag. Energy-dispersive X-ray (E-DX) spectrum showed the elemental composition of synthesized nanoparticles. Furthermore, TEM images confirm the formation of spherical shaped nano-silver particles with sizes r...

Environmental Science and Pollution Research

Annals of Tropical Medicine and Public Health

Exo-polysaccharides are polymers of carbohydrates secreted outside their cell walls by certain fu... more Exo-polysaccharides are polymers of carbohydrates secreted outside their cell walls by certain fungi and bacteria. Marine microorganisms have considerable osmotic resistance and cause exo polysaccharides to be produced also in salt concentrations. The bacterial exo polysaccharide was isolated from the marine ecosystem. Samples of marine soil and sea water are gathered from Parangipettai, Pichavaram, Cuddalore, Poombuhar, Nagapattinam coastal areas in Tamilnadu, South India. In the present study, marine bacteria were isolated and screened for the production of exopolysaccharides using different screening methods viz., Congo red agar plate, String test, Congo red-Trypan Blue Assay method. Thus this study demonstrated that the eight marine bacterial isolates may prove to be potential strain for commercial production of exopolysaccharides.

This comprehensive study on triple-negative breast cancer (TNBC) demonstrates a pioneering approa... more This comprehensive study on triple-negative breast cancer (TNBC) demonstrates a pioneering approach by exploring metabolic pathways, specifically focusing on the alkaline glucose isomer, glucosodiene, as a potential therapy. The case report provides a detailed account of a 42-year-old TNBC patient with lymph node metastasis, showcasing the efficacy of glucosodiene treatment in restoring normal vital functions and suppressing cellular activity. Overall, the study contributes valuable insights for developing individualized treatment plans and establishing robust follow-up protocols for TNBC patients.

CRC Press eBooks, Apr 5, 2023

Advances in Materials Science and Engineering

Water pollution is a global issue because of potentially lethal toxins. Polymeric nanomaterials a... more Water pollution is a global issue because of potentially lethal toxins. Polymeric nanomaterials are making their way into water treatment processes and are being utilized to efficiently remove a variety of pollutants. Polymeric nanomaterials are a popular option for a solution because they have a high adsorption capacity and a high surface charge. Nanocomposites have recently come to the attention of those working in the field of water treatment in order to more effectively remove contaminants. Polymeric composites are based on biopolymers and are being developed. These all quickly reached the industrial standards because of their low impact on the natural world. Chitosan is one of the biopolymers that are used extensively. Moreover, it is one of the most highly preferred biopolymers. It is simple to scale up and is readily available. The incorporation of nanomaterials into the biopolymer enables better control over the shape, size, and morphology of the particle, as well as an incr...

Biogenic Sustainable Nanotechnology

International Journal of Molecular Sciences, 2020

Scaffolds are important to tissue regeneration and engineering because they can sustain the conti... more Scaffolds are important to tissue regeneration and engineering because they can sustain the continuous release of various cell types and provide a location where new bone-forming cells can attach and propagate. Scaffolds produced from diverse processes have been studied and analyzed in recent decades. They are structurally efficient for improving cell affinity and synthetic and mechanical strength. Carbon nanotubes are spongy nanoparticles with high strength and thermal inertness, and they have been used as filler particles in the manufacturing industry to increase the performance of scaffold particles. The regeneration of tissue and organs requires a significant level of spatial and temporal control over physiological processes, as well as experiments in actual environments. This has led to an upsurge in the use of nanoparticle-based tissue scaffolds with numerous cell types for contrast imaging and managing scaffold characteristics. In this review, we emphasize the usage of carbon...

One of the potential applications of nanotechnology is that they provide promising improvements i... more One of the potential applications of nanotechnology is that they provide promising improvements in the field of sensor technology. In search for better electrochemical performance the use of nanomaterials in place of conventional one (micro crystalline transition metal oxides) has emerged as excellent alternative. In this work, ZnO nanowires were synthesized by wet chemical method. The precursors used for this experiment involves zinc sulphate, ammonium hydroxide, sodium hydroxide. The precursor's acts as both ...

Biogenic Sustainable Nanotechnology

This goal of study is to enquire how tourism correlates with a country’s image as indicated in re... more This goal of study is to enquire how tourism correlates with a country’s image as indicated in recent marketing literature, a majority of tourists will rely one’s image of a country rather than the travel itself or one’s economic benefit from the travel. The purpose of this study is to verify the effect that a country’s image has upon tourist attitudes and behavioral intentions. In this aim, the targets of the survey were Chinese tourists which comprise a large majority of Jeju foreign tourists as per the results released by the Korea Tourism Organization and Jeju Tourism Association in 2009. The results of the study indicate that, as long as there is an interdependent and complementary relationship among the country image, the tourist destination attitude and tourist behavioral intentions, cooperation and diversified efforts are required to induce positive attitudes and behavioral intentions of tourists. As tourist destination attitudes are very important factors for tourist behavi...

In recent years, nanotechnology has developed to a stage that makes it possible to produce, chara... more In recent years, nanotechnology has developed to a stage that makes it possible to produce, characterize and specifically tailor the structural and functional properties of nanoparticles for clinical applications. Cartilage damage is typically associated with work and athletic injuries, and commonly occurs in conjunction with ACL tears and other ligament problems. Cartilage does not grow back, so treatments to regenerate the tissue are critical. The new biomedical therapy involving nanotechnology promotes the growth of new, stronger cartilage to aid in the treatment of joint injuries. This review article analyses the various technologies available for the diagnostic and therapeutic potentials of nanotechnology towards chronic arthritis.

Nanotechnology and nanoscience are considered to be the “hot” research areas of the decade and ha... more Nanotechnology and nanoscience are considered to be the “hot” research areas of the decade and have attracted the attention of many researchers. The discovery of sophisticated nanomaterial characterization techniques has accelerated their research. The application of numerous morphological and physicochemical characterization tools for effectively resolving their shape, charge, size, surface coatings, and functional groups has improved the human understanding of the nanoworld. Furthermore, these techniques are vital to resolve the tolerable variation in surface chemistry without altering the material characteristics. This chapter sheds light on the most commonly used physicochemical characterization tools, to study nanoscale materials for biofuel production. The most commonly used techniques are reported in this chapter.

11 Published By: Blue Eyes Intelligence Engineering & Sciences Publication Retrieval Number:F1003... more 11 Published By: Blue Eyes Intelligence Engineering & Sciences Publication Retrieval Number:F10030476S519/19 ©BEIESP Abstract: The solar energy is the potential renewable green energy supply while considering the provision of sunlight in abundance and requirement for clean and renewable source of energy. The quantum dots sensitized solar cells (QDSC) provide an alternative perception to current photovoltaic devices. Quantum dots are colloidal nanocrystalline semiconductors possessing distinctive properties owing to quantum confinement effects. Quantum dots synthesis is based on an aqueous medium involving cadmium sulphate, zinc acetate, thiourea and ammonium hydroxide and assemble these quantum dots with nanoporous TiO2 films for quantum dots-sensitized solar cell applications. Titanium dioxide nanowires (TNW) were fabricated by a wet chemical method. Physical and chemical properties of the formed nanoparticles were differentiated using field emission scanning electron microscope (F...

In our work, electrical and optoelectronic properties of P-type porous silicon (PSi) prepared usi... more In our work, electrical and optoelectronic properties of P-type porous silicon (PSi) prepared using chemical etching method are studied, specifically capacitancevoltage (C-V), current-voltage (I-V), responsivity and detectivity severally are analyzed. It had been found that electrical characteristics of porous Si samples measured in dark (Id) and below illumination (IPh) will be fitted well by the equations of thermal emission. From this point of view, Schottky barrier height (ɸB) and ideality factor (n) of made-up photodetectors were calculated. The I-V characteristics of dark and illuminations that passes current through the PSi layer reduced by increasing the etching current, as a result of increasing the electrical resistance of PSi layer and therefore the optimum value of ideality factor is (2.7), whereas from C-V characteristic determined that in-built potential accumulated with increasing etching current. The results show that there are clear results for better performance of...

Due to the capacity to moderate metals to their nanometer size, nanobiotechnology is gaining enor... more Due to the capacity to moderate metals to their nanometer size, nanobiotechnology is gaining enormous popularity in this period, which effectively changes its chemical, physical and optical properties. Recent progress in nanoscience and technology has also managed to the growth of new nanomaterials (NMs), eventually increasing toxic and potential health effects. There has been growing attention in evolving eco-friendly methods for metal nanoparticles (NPs) synthesis. The main purpose of the study is to reduce the harmful influences of synthetic processes, associated substances alongside other derivatives. The use of diverse biomaterials (BMs) for NP synthesis is examined as a promising method in green nanotechnology. However, most of the techniques currently available are costly; utilizing the natural properties includes plants, bacteria, fungi and algae to manufacture low-cost, non-toxic and energy-efficient metallic NPs that are environmentally friendly. Besides, biologically synt...

SN Applied Sciences

In this present work, we described a bio-reduction method for the generation of silver nanopartic... more In this present work, we described a bio-reduction method for the generation of silver nanoparticles (AgNPs) using aqueous leaf extract of Micrargeria wightii (M. wightii), which is a gifted alternative to other physicochemical routes. The prepared AgNPs were characterized by UV–visible spectroscopy (UV–vis), Fourier Transform Infrared Spectroscopy (FT-IR), X-ray diffraction (X-RD), Transmission Electron Microscopy (TEM) with EDX and Dynamic light scattering (DLS). UV–visible spectrum showed a characteristic absorption peak at 440 nm of synthesized AgNPs. FT-IR analysis confirmed the existence of plant metabolites, which are responsible for the reduction of Ag (I) ions into Ag (0) NPs. X-RD pattern studies confirm the presence of the pure face-centered cubiccrystalline nature of Ag. Energy-dispersive X-ray (E-DX) spectrum showed the elemental composition of synthesized nanoparticles. Furthermore, TEM images confirm the formation of spherical shaped nano-silver particles with sizes r...

Environmental Science and Pollution Research

Annals of Tropical Medicine and Public Health

Exo-polysaccharides are polymers of carbohydrates secreted outside their cell walls by certain fu... more Exo-polysaccharides are polymers of carbohydrates secreted outside their cell walls by certain fungi and bacteria. Marine microorganisms have considerable osmotic resistance and cause exo polysaccharides to be produced also in salt concentrations. The bacterial exo polysaccharide was isolated from the marine ecosystem. Samples of marine soil and sea water are gathered from Parangipettai, Pichavaram, Cuddalore, Poombuhar, Nagapattinam coastal areas in Tamilnadu, South India. In the present study, marine bacteria were isolated and screened for the production of exopolysaccharides using different screening methods viz., Congo red agar plate, String test, Congo red-Trypan Blue Assay method. Thus this study demonstrated that the eight marine bacterial isolates may prove to be potential strain for commercial production of exopolysaccharides.