Lopez Martinez - Academia.edu (original) (raw)
Papers by Lopez Martinez
Acta Otorrinolaringologica Espanola, Feb 1, 2005
Introducción: La videofibrosomnoscopia es una técnica que permite la visualización de la faringe ... more Introducción: La videofibrosomnoscopia es una técnica que permite la visualización de la faringe de un paciente al que se le ha inducido el sueño farmacológicamente. De este modo se puede diagnosticar la o las zonas causantes de la vibración y colapso de los pacientes con roncopatía crónica. Material y métodos: La prueba se realizó a un total de 51 pacientes. A todos se les realizó una anamnesis estándar y una exploración otorrinolaringológica como parte del diagnóstico habitual. Resultados: La zona de obstrucción más frecuentemente encontrada fue el velo del paladar en el 90,4%, seguido de la base de la lengua en el 38,5%. El colapso multinivel se dio en el 60,7%. No se han hallado correlaciones entre la obstrucción hallada en la consulta y la vista durante la VFS. Conclusiones: La VFS es una técnica útil en el diagnóstico del paciente con roncopatía y es aconsejable su utilización para saber con certeza el tipo de obstrucción del paciente.
Revista Clinica Espanola, Mar 1, 1976
Acta Otorrinolaringologica Espanola, 2006
Objetivos: Determinar la aplicabilidad de la técnica del ganglio centinela (GC) en tumores N0 de ... more Objetivos: Determinar la aplicabilidad de la técnica del ganglio centinela (GC) en tumores N0 de laringe. Material y métodos: Realizamos un estudio prospectivo en 19 pacientes con tumores N0 de laringe. Infiltramos peritumoralmente 1mCi de nanocoloides de albúmina marcados con 99m Tc con endoscopio rígido bajo anestesia general. Detectamos el GC intraoperatoriamente con una sondagamma durante el vaciamiento cervical. Los resultados histológicos del GC se comparan con los del vaciamiento cervical. Resultados: Identificamos el GC en 17 pacientes (89,47%). Once pacientes presentaron GC libres de tumor, reflejando correctamente el estatus del cuello (pN0). Tres pacientes presentaron metástasis en el GC l. Encontramos 3 falsos negativos. La sensibilidad de la técnica fue 50,0% (3/6) y el VPN de un 78,6%. Conclusiones: Pensamos que para que la técnica del GC sea aplicable en tumores de laringe se precisan de un mayor número de estudios, siendo fundamental la realización de un correcta selección de los pacientes.
Ans Alimentacion Nutricion Y Salud, 1997
Nutricion Hospitalaria Organo Oficial De La Sociedad Espanola De Nutricion Parenteral Y Enteral, 1997
The application of artificial nutritional treatment in critical patients, nowadays is a completel... more The application of artificial nutritional treatment in critical patients, nowadays is a completely accepted fact. To a large degree this is due to the advances made in the understanding of the metabolic response shown by patients against a severe and persistent aggression. One of the entities which presents the highest mortality in critical patients, is the Acute Respiratory Distress Syndrome (ARDS), which one understands as the pulmonary response to different types of aggression. To understand the metabolic implications in the face of the development of this syndrome, would permit a better understanding of the need to treat these patients and to establish the nutritional standards which are most adequate to each different metabolic alteration. It would not only be important to understand the most effective method for calculating the caloric needs of these patients, but we shall also have to deepen our understanding of possible harmful effects of the different substrates, which undoubtedly could condition morbidity. This is why in this review we focus on the intimate pulmonary mechanism, both in healthy conditions as in those of disease, in order to extrapolate conclusions which are potentially applicable to patients suffering from an acute pulmonary lesion, as those suffering from ARDS: A main role shall be played the assessment of the administration of macronutrients in the form carbohydrates, lipids, and amino acid particles, due to the implications which each of these may have on the lesioned lung and its ventilatory capacity.
Acta Otorrinolaringologica Espanola, Feb 1, 2002
The main goal for performing surgery for chronic otitis media is to eliminate the disease and imp... more The main goal for performing surgery for chronic otitis media is to eliminate the disease and improve hearing whenever possible. Persistent drainage of a mastoid cavity means failure of surgery and of achieving the goal. In this study, we present our department's attitude for suppurative mastoid cavities as well as the reasons that do not allow adequate control of them.
Anales Otorrinolaringologicos Ibero Americanos, 2003
Anales Otorrinolaringologicos Ibero Americanos, Feb 1, 1993
Anales Otorrinolaringologicos Ibero Americanos, Feb 1, 2003
In our milieu, Dr. Peset Hospital, Valencia, we have collected between 1979 and 1998, a total amo... more In our milieu, Dr. Peset Hospital, Valencia, we have collected between 1979 and 1998, a total amount of 683 thyroidectomies. Between them 101 carcinomata and 582 bening thyroid pathology. In this work are studied the bening pathology treated surgically. 86.4 percent were women and 13.6% men. Middle age 45 years. By complementary explorations, echography the solid single node by 41.9 percent of cases and solid numerous nodes by 34.7% were the more important findings found. By gammagraphy with greater frequency discovered a cold single node by 44.2% of cases. Anatomopathological types more frequently found were single hyperplastic node (13.3%), multiple hyperplastic nodes (27.6%), spreading hyperplasy (9.1%) and follicular adenoma (37.4%). The aim of this work is the comparative study of findings of complementary explorations with the anatomopathological results gained through the surgical pieces.
Http Dx Doi Org 10 1080 03602550701580870, Dec 26, 2007
Acta Otorrinolaringologica Espanola, Aug 1, 2006
Objetivos: Determinar la aplicabilidad de la técnica del ganglio centinela (GC) en tumores N0 de ... more Objetivos: Determinar la aplicabilidad de la técnica del ganglio centinela (GC) en tumores N0 de laringe. Material y métodos: Realizamos un estudio prospectivo en 19 pacientes con tumores N0 de laringe. Infiltramos peritumoralmente 1mCi de nanocoloides de albúmina marcados con 99m Tc con endoscopio rígido bajo anestesia general. Detectamos el GC intraoperatoriamente con una sondagamma durante el vaciamiento cervical. Los resultados histológicos del GC se comparan con los del vaciamiento cervical. Resultados: Identificamos el GC en 17 pacientes (89,47%). Once pacientes presentaron GC libres de tumor, reflejando correctamente el estatus del cuello (pN0). Tres pacientes presentaron metástasis en el GC l. Encontramos 3 falsos negativos. La sensibilidad de la técnica fue 50,0% (3/6) y el VPN de un 78,6%. Conclusiones: Pensamos que para que la técnica del GC sea aplicable en tumores de laringe se precisan de un mayor número de estudios, siendo fundamental la realización de un correcta selección de los pacientes.
Acta Otorrinolaringologica Espanola, 2002
Two cases of idiopathic brain herniation into the middle ear without previous surgery are reporte... more Two cases of idiopathic brain herniation into the middle ear without previous surgery are reported. Brain herniation is an unusual pathology, usually related to middle ear surgery. The idiopathic appearance of this disease is the secondly most frequent cause. Its origin is believed to be related to a congenital defect of tegmen timpani. Two elements, both rare, are emphazised: the spontaneous bilateral presentation in one of the cases, and the CSF leak as an initial symptom. We present a review of the literature, describing epidemiology results and the main accepted etiology theories. We discuss the diagnosis and treatment methods: magnetic resonance imaging and surgery.
Anales Otorrinolaringologicos Ibero Americanos, Feb 1, 1999
The aim of this work is to highlight the significance on features more frequent of the troubles o... more The aim of this work is to highlight the significance on features more frequent of the troubles of the balance and vestibular system in our environment. Also we present a statistic about the symptomatology, on the results of vestibular examination and the diagnoses of a series of patients, of all ages, suffering vertigo, and studied in our department.
Anales Otorrinolaringologicos Ibero Americanos, 2001
We performed a prospective study over 19 patients to evaluate the efficacy of the Epley's particl... more We performed a prospective study over 19 patients to evaluate the efficacy of the Epley's particle repositioning maneuver for treatment of the benign paroxysmal positional vertigo (BPPV), 78.9% were cured through this procedure, so we find this method as very useful for improving the BPPV.
Acta Otorrinolaringologica Espanola, Oct 1, 2002
Documento descargado de http://www.elsevier.es el 01/09/2016. Copia para uso personal, se prohíbe... more Documento descargado de http://www.elsevier.es el 01/09/2016. Copia para uso personal, se prohíbe la transmisión de este documento por cualquier medio o formato.
Acta Otorrinolaringologica Espanola, Apr 1, 2004
KEY WORDS: Pectoral major flap. Tracheoesophageal fistula. PALABRAS CLAVE: Colgajo pectoral mayor... more KEY WORDS: Pectoral major flap. Tracheoesophageal fistula. PALABRAS CLAVE: Colgajo pectoral mayor. Fístula traqueoesofágica. Documento descargado de http://www.elsevier.es el 01/09/2016. Copia para uso personal, se prohíbe la transmisión de este documento por cualquier medio o formato.
Mycoses, 2006
Several allergens from Alternaria alternata have been isolated allowing some of them to be identi... more Several allergens from Alternaria alternata have been isolated allowing some of them to be identified and characterised. Despite the fact that the major allergen of A. alternata (Alt a 1) has been extensively produced by recombinant technology, its biological activity still remains unknown. In the present study, extracts from culture filtrates were used to evaluate the intra-specific variability of the enzymes and also as a source for isolating and purifying native Alt a 1. This was purified by affinity chromatography using antibody anti-recombinant Alt a 1 (produced in Escherichia coli). Enzyme activities were analysed by the API-ZYM System screening method. Results demonstrated the high variability of enzyme activities among the different strains.
Anales Otorrinolaringologicos Ibero Americanos, Feb 1, 1997
25 patients with epidermoid carcinoma of the larynx underwent staging of cervical adenopathies by... more 25 patients with epidermoid carcinoma of the larynx underwent staging of cervical adenopathies by magnetic resonance imaging (MRI). All patients subsequently underwent neck dissection. The MRI results were compared with the histopathological findings ans those gained through previous palpation. MRI correctly staged 54.1% of patients with a sensitivity of 66% and a specificity of 74%.
Acta Otorrinolaringologica Espanola, Nov 1, 2002
Documento descargado de http://zl.elsevier.es el 04/01/2014. Copia para uso personal, se prohíbe ... more Documento descargado de http://zl.elsevier.es el 04/01/2014. Copia para uso personal, se prohíbe la transmisión de este documento por cualquier medio o formato.
Acta Otorrinolaringologica Espanola, Feb 1, 2005
Introducción: La videofibrosomnoscopia es una técnica que permite la visualización de la faringe ... more Introducción: La videofibrosomnoscopia es una técnica que permite la visualización de la faringe de un paciente al que se le ha inducido el sueño farmacológicamente. De este modo se puede diagnosticar la o las zonas causantes de la vibración y colapso de los pacientes con roncopatía crónica. Material y métodos: La prueba se realizó a un total de 51 pacientes. A todos se les realizó una anamnesis estándar y una exploración otorrinolaringológica como parte del diagnóstico habitual. Resultados: La zona de obstrucción más frecuentemente encontrada fue el velo del paladar en el 90,4%, seguido de la base de la lengua en el 38,5%. El colapso multinivel se dio en el 60,7%. No se han hallado correlaciones entre la obstrucción hallada en la consulta y la vista durante la VFS. Conclusiones: La VFS es una técnica útil en el diagnóstico del paciente con roncopatía y es aconsejable su utilización para saber con certeza el tipo de obstrucción del paciente.
Revista Clinica Espanola, Mar 1, 1976
Acta Otorrinolaringologica Espanola, 2006
Objetivos: Determinar la aplicabilidad de la técnica del ganglio centinela (GC) en tumores N0 de ... more Objetivos: Determinar la aplicabilidad de la técnica del ganglio centinela (GC) en tumores N0 de laringe. Material y métodos: Realizamos un estudio prospectivo en 19 pacientes con tumores N0 de laringe. Infiltramos peritumoralmente 1mCi de nanocoloides de albúmina marcados con 99m Tc con endoscopio rígido bajo anestesia general. Detectamos el GC intraoperatoriamente con una sondagamma durante el vaciamiento cervical. Los resultados histológicos del GC se comparan con los del vaciamiento cervical. Resultados: Identificamos el GC en 17 pacientes (89,47%). Once pacientes presentaron GC libres de tumor, reflejando correctamente el estatus del cuello (pN0). Tres pacientes presentaron metástasis en el GC l. Encontramos 3 falsos negativos. La sensibilidad de la técnica fue 50,0% (3/6) y el VPN de un 78,6%. Conclusiones: Pensamos que para que la técnica del GC sea aplicable en tumores de laringe se precisan de un mayor número de estudios, siendo fundamental la realización de un correcta selección de los pacientes.
Ans Alimentacion Nutricion Y Salud, 1997
Nutricion Hospitalaria Organo Oficial De La Sociedad Espanola De Nutricion Parenteral Y Enteral, 1997
The application of artificial nutritional treatment in critical patients, nowadays is a completel... more The application of artificial nutritional treatment in critical patients, nowadays is a completely accepted fact. To a large degree this is due to the advances made in the understanding of the metabolic response shown by patients against a severe and persistent aggression. One of the entities which presents the highest mortality in critical patients, is the Acute Respiratory Distress Syndrome (ARDS), which one understands as the pulmonary response to different types of aggression. To understand the metabolic implications in the face of the development of this syndrome, would permit a better understanding of the need to treat these patients and to establish the nutritional standards which are most adequate to each different metabolic alteration. It would not only be important to understand the most effective method for calculating the caloric needs of these patients, but we shall also have to deepen our understanding of possible harmful effects of the different substrates, which undoubtedly could condition morbidity. This is why in this review we focus on the intimate pulmonary mechanism, both in healthy conditions as in those of disease, in order to extrapolate conclusions which are potentially applicable to patients suffering from an acute pulmonary lesion, as those suffering from ARDS: A main role shall be played the assessment of the administration of macronutrients in the form carbohydrates, lipids, and amino acid particles, due to the implications which each of these may have on the lesioned lung and its ventilatory capacity.
Acta Otorrinolaringologica Espanola, Feb 1, 2002
The main goal for performing surgery for chronic otitis media is to eliminate the disease and imp... more The main goal for performing surgery for chronic otitis media is to eliminate the disease and improve hearing whenever possible. Persistent drainage of a mastoid cavity means failure of surgery and of achieving the goal. In this study, we present our department's attitude for suppurative mastoid cavities as well as the reasons that do not allow adequate control of them.
Anales Otorrinolaringologicos Ibero Americanos, 2003
Anales Otorrinolaringologicos Ibero Americanos, Feb 1, 1993
Anales Otorrinolaringologicos Ibero Americanos, Feb 1, 2003
In our milieu, Dr. Peset Hospital, Valencia, we have collected between 1979 and 1998, a total amo... more In our milieu, Dr. Peset Hospital, Valencia, we have collected between 1979 and 1998, a total amount of 683 thyroidectomies. Between them 101 carcinomata and 582 bening thyroid pathology. In this work are studied the bening pathology treated surgically. 86.4 percent were women and 13.6% men. Middle age 45 years. By complementary explorations, echography the solid single node by 41.9 percent of cases and solid numerous nodes by 34.7% were the more important findings found. By gammagraphy with greater frequency discovered a cold single node by 44.2% of cases. Anatomopathological types more frequently found were single hyperplastic node (13.3%), multiple hyperplastic nodes (27.6%), spreading hyperplasy (9.1%) and follicular adenoma (37.4%). The aim of this work is the comparative study of findings of complementary explorations with the anatomopathological results gained through the surgical pieces.
Http Dx Doi Org 10 1080 03602550701580870, Dec 26, 2007
Acta Otorrinolaringologica Espanola, Aug 1, 2006
Objetivos: Determinar la aplicabilidad de la técnica del ganglio centinela (GC) en tumores N0 de ... more Objetivos: Determinar la aplicabilidad de la técnica del ganglio centinela (GC) en tumores N0 de laringe. Material y métodos: Realizamos un estudio prospectivo en 19 pacientes con tumores N0 de laringe. Infiltramos peritumoralmente 1mCi de nanocoloides de albúmina marcados con 99m Tc con endoscopio rígido bajo anestesia general. Detectamos el GC intraoperatoriamente con una sondagamma durante el vaciamiento cervical. Los resultados histológicos del GC se comparan con los del vaciamiento cervical. Resultados: Identificamos el GC en 17 pacientes (89,47%). Once pacientes presentaron GC libres de tumor, reflejando correctamente el estatus del cuello (pN0). Tres pacientes presentaron metástasis en el GC l. Encontramos 3 falsos negativos. La sensibilidad de la técnica fue 50,0% (3/6) y el VPN de un 78,6%. Conclusiones: Pensamos que para que la técnica del GC sea aplicable en tumores de laringe se precisan de un mayor número de estudios, siendo fundamental la realización de un correcta selección de los pacientes.
Acta Otorrinolaringologica Espanola, 2002
Two cases of idiopathic brain herniation into the middle ear without previous surgery are reporte... more Two cases of idiopathic brain herniation into the middle ear without previous surgery are reported. Brain herniation is an unusual pathology, usually related to middle ear surgery. The idiopathic appearance of this disease is the secondly most frequent cause. Its origin is believed to be related to a congenital defect of tegmen timpani. Two elements, both rare, are emphazised: the spontaneous bilateral presentation in one of the cases, and the CSF leak as an initial symptom. We present a review of the literature, describing epidemiology results and the main accepted etiology theories. We discuss the diagnosis and treatment methods: magnetic resonance imaging and surgery.
Anales Otorrinolaringologicos Ibero Americanos, Feb 1, 1999
The aim of this work is to highlight the significance on features more frequent of the troubles o... more The aim of this work is to highlight the significance on features more frequent of the troubles of the balance and vestibular system in our environment. Also we present a statistic about the symptomatology, on the results of vestibular examination and the diagnoses of a series of patients, of all ages, suffering vertigo, and studied in our department.
Anales Otorrinolaringologicos Ibero Americanos, 2001
We performed a prospective study over 19 patients to evaluate the efficacy of the Epley's particl... more We performed a prospective study over 19 patients to evaluate the efficacy of the Epley's particle repositioning maneuver for treatment of the benign paroxysmal positional vertigo (BPPV), 78.9% were cured through this procedure, so we find this method as very useful for improving the BPPV.
Acta Otorrinolaringologica Espanola, Oct 1, 2002
Documento descargado de http://www.elsevier.es el 01/09/2016. Copia para uso personal, se prohíbe... more Documento descargado de http://www.elsevier.es el 01/09/2016. Copia para uso personal, se prohíbe la transmisión de este documento por cualquier medio o formato.
Acta Otorrinolaringologica Espanola, Apr 1, 2004
KEY WORDS: Pectoral major flap. Tracheoesophageal fistula. PALABRAS CLAVE: Colgajo pectoral mayor... more KEY WORDS: Pectoral major flap. Tracheoesophageal fistula. PALABRAS CLAVE: Colgajo pectoral mayor. Fístula traqueoesofágica. Documento descargado de http://www.elsevier.es el 01/09/2016. Copia para uso personal, se prohíbe la transmisión de este documento por cualquier medio o formato.
Mycoses, 2006
Several allergens from Alternaria alternata have been isolated allowing some of them to be identi... more Several allergens from Alternaria alternata have been isolated allowing some of them to be identified and characterised. Despite the fact that the major allergen of A. alternata (Alt a 1) has been extensively produced by recombinant technology, its biological activity still remains unknown. In the present study, extracts from culture filtrates were used to evaluate the intra-specific variability of the enzymes and also as a source for isolating and purifying native Alt a 1. This was purified by affinity chromatography using antibody anti-recombinant Alt a 1 (produced in Escherichia coli). Enzyme activities were analysed by the API-ZYM System screening method. Results demonstrated the high variability of enzyme activities among the different strains.
Anales Otorrinolaringologicos Ibero Americanos, Feb 1, 1997
25 patients with epidermoid carcinoma of the larynx underwent staging of cervical adenopathies by... more 25 patients with epidermoid carcinoma of the larynx underwent staging of cervical adenopathies by magnetic resonance imaging (MRI). All patients subsequently underwent neck dissection. The MRI results were compared with the histopathological findings ans those gained through previous palpation. MRI correctly staged 54.1% of patients with a sensitivity of 66% and a specificity of 74%.
Acta Otorrinolaringologica Espanola, Nov 1, 2002
Documento descargado de http://zl.elsevier.es el 04/01/2014. Copia para uso personal, se prohíbe ... more Documento descargado de http://zl.elsevier.es el 04/01/2014. Copia para uso personal, se prohíbe la transmisión de este documento por cualquier medio o formato.