Lubna Shah - Academia.edu (original) (raw)

Papers by Lubna Shah

Pakistan Journal of Medical and Health Sciences

Objective: Adults with neck-of-femur fractures will be compared between two and three cannulated ... more Objective: Adults with neck-of-femur fractures will be compared between two and three cannulated screws for fixation in this study. Study Design: Comparative/Experimental study Place and Duration: Orthopaedics and Trauma Department of Bacha Khan Medical College, Mardan and the department of Orthopaedics, Gambat Institutes of Medical and Science, Sindh during the period from April 2021 to September 2021 Methods: There were 90 patients of both genders had garden type fractures of neck of femur with ages 15-55years were included. Age, gender, and the reason of the fracture were among the variables collected after patients provided written consent. Patients were equally segregated into two groups. Group I had 45 patients and received cannulated screws fixation and in group II 45 patients received three cannulated screws fixation. Post treatment radiological union was assessed and compared at the 14th week. We used SPSS 23.0 to analyze complete data. Results: There were majority males 75...

Journal of Business & Retail Management Research, 2020

This study investigates the main reasons behind the purchase of Aramco shares. It examines whethe... more This study investigates the main reasons behind the purchase of Aramco shares. It examines whether the following financial variables: financial literacy, financial self-efficacy, financial behavior and financial perceived value influence the attitude towards Saudi Aramco's IPO. Other variables dealing with environmental concerns and patriotism perception were added to this analysis, making it one of the pioneer studies in this field. A primary data collection through a survey questionnaire and structural equation modeling (SPSS-AMOS-26) were followed to study our research hypotheses. Our findings highlight a significant relationship between patriotism level, environmental concerns and attitude towards Saudi Aramco's IPO, which may encourage financial institutions to slot this investors’ psychosocial side in their marketing strategy, making environment sustainability a part of their corporate identity. Our study will also open the way for further investigation on the role pla...

Computational and Mathematical Organization Theory, 2018

The process of diagnosis, intervention, conservation, restoration and maintenance of built cultur... more The process of diagnosis, intervention, conservation, restoration and maintenance of built cultural heritage requires complete and accurate knowledge about tangible as well as intangible aspects of their past and present. Comprehensive and precise knowledge about built cultural heritage structures, their functionality, location, environment and any sudden disturbance needs to be digitized for long lasting preservation of the resource. Discrepancy or scarcity of information can lead to errors and even irrecoverable damages. Both human and natural disasters are destroying cultural heritage objects, buildings and sites which have great value and significance in human history. This paper is aimed to provide a comprehensive discussion of state of the art knowledge representation and knowledge management solutions, specifically designed for improving built cultural heritage information preservation. This paper suggests that semantic digitization of built cultural heritage data is the best way forward. Traditional standards in built heritage metadata schemas lack the description of key aspects of 3-D modeling while, 3-D modeling standards such as geographical information system (GIS) and building information modeling (BIM) do not provide sufficient representation of historical data related to a built heritage (BH) structure. This paper proposes a model for representing architectural as well as historical data relevant to a BH site, using semantic web technologies and building information modeling standards.

Cluster Computing, 2018

This paper presents a comprehensive survey on knowledge retrieval of historical concepts using se... more This paper presents a comprehensive survey on knowledge retrieval of historical concepts using semantic web technologies. The scope of this discussion encompasses research material in the field of computing and humanities including but not limited to Cultural Heritage, Museum and Digital Library research. Semantic web techniques used to describe, store, search, query and retrieve historic concepts such as RDF, RDFs, OWL, and Ontologies are discussed along with other extensively researched methods from domains like Natural Language Processing and Computer Vision. The discussion elaborates on Ontological-enabled information retrieval and the concept of new knowledge discovery. This work presents a comprehensive set of problems identified in the field of information retrieval and their solutions through the semantic web along with an insight in the future directions and the open-ended questions in the domain of retrieval of historic concept. Keywords Information retrieval Á Knowledge retrieval Á Historical concepts Á Semantic web Á Cultural heritage Á Museum Á Manuscripts Á Ontology-based knowledge retrieval Á Digital library

JBI Database of Systematic Reviews and Implementation Reports, 2016

Review question/objective: This systematic review aims to identify the effective de-escalation st... more Review question/objective: This systematic review aims to identify the effective de-escalation strategies that nurses utilize to prevent aggressive behaviors. Specifically, this review has the following objectives: To explore effective strategies used by nurses to de-escalate aggression in patients in the psychiatric setting. To identify the key components of effective strategies in the de-escalation of aggression in patients by nurses in the psychiatric setting.

Faculty of Health Institute of Health and Biomedical Innovation School of Nursing, Apr 1, 2012

Considered a condition of the elderly population, stroke will soon be the leading cause of death ... more Considered a condition of the elderly population, stroke will soon be the leading cause of death globally. In Singapore it is the fourth leading cause of death after cancer and heart disease. Subarachnoid haemorrhage, when compared with an embolic stroke, has a more devastating outcome because of the deleterious complications associated with it. Vasospam, re-bleeding and global cerebral ischemia are three of the most prominent complications. Therefore, nursing care and interventions developed to reduce the incidence of complications and optimise neurological function are critical in the acute phase of this condition. Using a casestudy approach this article will discuss and offer a rationale to a number of key nursing interventions based around a nursing care plan designed to reduce the incidence of complications.

Proquest Dissertations and Theses Thesis University of Delaware 2010 Publication Number Aat 3423374 Isbn 9781124241289 Source Dissertation Abstracts International Volume 71 11 Section B Page 6833 204 P, 2010

Prediction of Binding Mode of Bisphenol-A (A Carcinogen) in Estrogen and Testosterone Receptors b... more Prediction of Binding Mode of Bisphenol-A (A Carcinogen) in Estrogen and Testosterone Receptors by Applying Computational Docking Approach

Background: Bisphenol A (BPA) displays weak estrogenic properties and could be a weak carcinogen.... more Background: Bisphenol A (BPA) displays weak estrogenic properties and could be a weak carcinogen. BPA exposure during the perinatal period has been reported to alter both prostate and mammary gland development in ways that may render these organs more susceptible to the development of neoplasia or preneoplastic conditions with subsequent exposures to strong tumour-initiating or tumour-promoting regimens. Methods: Molecular Operating Environment (MOE-2012) software was used to perform docking calculations. This software returned affinity energy values for several ligand conformations. Subsequently, we used PyMole 1.4 and Ligand Scout 3.1 to check the stereochemistry of chiral carbons, substructure, superstructure, number of rotatable bonds, number of rings, number of donor groups, and hydrogen bond receptors. Results: some compounds involved in cancer, here computationally we predict the distortion behavior of Bis-Phenol A in equilibration in estrogen and testosterone receptors, and ...

Cyclooxygenases, which exists in two forms COX-1 and COX-2, are essential enzymes in the synthesi... more Cyclooxygenases, which exists in two forms COX-1 and COX-2, are essential enzymes in the synthesis of Prostaglandin H, involves in the biosynthesis of Thromboxanes, and Prostacyclins. The inhibition of biological activity of these enzymes has very therapeutic importance in many pathological conditions. Many non-steroidal anti-inflammatory drugs (NSAIDs) have been used against these enzymes but mostly lead to side effects. Recently reported several synthetic compounds (5-substituted 1H-terazoles) which are experimentally shown to inhibit cyclooxygenases activity in the low micromolar range. We performed a computational study to help identify possible binding modes by docking these compounds onto the active site of cyclooxygenase-2 (COX-2) and to characterize the structures of binding complexes via MOE-Dock as docking software. Good correlations were found in docking scores and experimental values of these compounds against COX-2. The top-ranked conformation of each compound was inter...

OA Drug Design and Delivery, 2013

Introduction Drug discovery and development is an intense, lengthy and an interdisciplinary ventu... more Introduction Drug discovery and development is an intense, lengthy and an interdisciplinary venture. Recently, a trend towards the use of in-silico chemistry and molecular modelling for computer-aided drug design has gained significant momentum. Insilico drug design skills are used in nanotechnology, molecular biology, biochemistry etc. The main benefit of the in-silico drug design is cost effective in research and development of drugs. There are wide ranges of software that are used in in-silico drug design, Grid computing, window based general PBPK/PD modelling software, PKUDDS for structure based drug design, APIS, JAVA, Perl and Python, in-silico drug design as well as software including software libraries. There are different techniques used in in-silico drug design visualization, homology, molecular dynamic, energy minimization molecular docking and QSAR etc. In-silico drug design can take part considerably in all stages of drug development from the preclinical discovery stage to late stage clinical development. Its exploitation in drug development helps in the selection of only a potent lead molecule and may thus thwart the late stage clinical failures; thereby a major diminution in cost can be achieved. This article gives an insight into all the aspects of in-silico drug design; its potential, drivers, current development and the future prospects. Conclusion In-silico methods have been of great importance in target identification and in prediction of novel drugs.

Archives of Psychiatric Nursing, 2014

Archives of Psychiatric Nursing, 2015

This study aimed to investigate the effect of a VR-based stress management program on people with... more This study aimed to investigate the effect of a VR-based stress management program on people with mood disorders. A quasi-experimental study was conducted in a tertiary hospital in Singapore, and a convenience sample of 22 was recruited. The program comprised three daily 1-hour sessions incorporating psychoeducation and VR-based relaxation practice. Participants who completed the program had significantly lowered subjective stress (t=6.91, p&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.001), depression (t=5.62, p&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.001), and anxiety (t=5.54, p&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.001); and increased skin temperature (F=17.71, p&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.001), perceived relaxation (F=26.20, p&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.001) and knowledge (F=13.77, p&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.001). Participants&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; feedback on the program was positive. Findings from this study contribute to improving clinical practice and serve as preliminary data to conduct more rigorous research in the future.

International Journal of Modern Physics B, 2006

We present magnetic measurements on iron ( Fe ) nanoparticles in the size range 10–30 nm produced... more We present magnetic measurements on iron ( Fe ) nanoparticles in the size range 10–30 nm produced by the Inert Gas Condensation process (IGC). Structural characterization studies show the presence of a core/shell structure, where the core is bcc Fe while the surface layer is Fe -oxide. Analysis of the magnetic measurements shows that the nanoparticles display very large uniaxial anisotropy, K eff ≈3 - 4 × 106 erg/cc. The observed room temperature coercivities lie in the range ≈600 – 973 Oe , much larger than those expected from the Stoner–Wohlfarth model using the bulk iron anisotropy. It can be inferred from the coercivity variation with the particle size that there is a general trend of the coercivity increasing with size, culminating finally in a decrease for high sizes (30 nm) possibly due to the onset of non-coherent magnetization reversal processes.

Bulletin of the American …, 2010

We have measured the changes of TMR and of barrier 1/$f$ resistance noise in sputtered, MgO-based... more We have measured the changes of TMR and of barrier 1/$f$ resistance noise in sputtered, MgO-based MTJs as a function of annealing time at 250, 380, and 430 circ^{\circ}circC. Although the behavior of TMR and of noise are anticorrelated at 380 and 430 circ^{\circ}circC, the ...

Bulletin of the American …, 2009

We have studied the evolution of tunneling magnetoresistance (TMR) and resistance noise in magnet... more We have studied the evolution of tunneling magnetoresistance (TMR) and resistance noise in magnetic tunnel junctions (MTJs) as a function of annealing time at 425$^{o}$C. Previously, we showed that short annealing times do lead to significant improvement in the MgO ...

Physical Review B, 2010

The competition between the interface crystallization and diffusion processes, their influence on... more The competition between the interface crystallization and diffusion processes, their influence on the onset of symmetry-filtering coherent tunneling of ⌬ 1 band electrons in the MgO-based magnetic tunnel junctions is investigated. Systematic study of the transport and magnetoresistance during thermal annealing of these junctions shows a unique behavior of the tunneling conductance in the parallel state. The optimal annealing time for achieving giant tunneling magnetoresistance at different temperatures is determined. The evolution of magnetoresistance consists of three distinct regions, responsible by different contributions from CoFeB electrodes and the MgO barrier. The whole phenomenon can be understood through an empirical model based on the Landauer tunneling picture.

Physica B: Condensed Matter, 2010

ABSTRACT Diluted magnetic oxide of Ce0.97Co0.03O2-delta powder was synthesized by standard solid-... more ABSTRACT Diluted magnetic oxide of Ce0.97Co0.03O2-delta powder was synthesized by standard solid-state reaction method. Oxidized or reduced samples were obtained via O2 or Ar/H2 annealing, respectively. Magnetic investigations found that the as sintered Ce0.97Co0.03O2-delta is ferromagnetic at room temperature. The saturation magnetic moments (MS) are highly enhanced by Ar/H2 annealing, while sharply diminished by O2 treatments. X-ray photoelectron spectroscopy (XPS) measurements show that Ce4+ ions are partially reduced to Ce3+ with additional oxygen vacancies (VO) being introduced by Ar/H2 annealing. The increase of VO by Ar/H2 annealing is further proved by Raman spectra in which a new Raman scattering peak appearing at the frequency of 465 cm-1. This fact contributes to the enhanced ferromagnetism observed in reduced Ce0.97Co0.03O2-delta. On the other hand, VO density is reduced via O2 annealing and thus leading to a decreased MS. On all accounts MS is found to be in direct ratio-dependent on VO density in Ce0.97Co0.03O2-delta. The experimental results are well consistent with the F-center mediated ferromagnetism mechanism recently found in some transitional metal (TM) doped oxides, and thus is very important in understanding the mechanism of the ferromagnetism (FM) origin in many TMs-doped insulating oxides.