Mônica Lotufo - Academia.edu (original) (raw)
Papers by Mônica Lotufo
Rev. Assoc. Paul. Cir. Dent, 2005
O figado pode ser afetado por agentes quimicos, fisicos ou biologicos. Atualmente, aceita-se a ex... more O figado pode ser afetado por agentes quimicos, fisicos ou biologicos. Atualmente, aceita-se a existencia de 9 virus hepatotropicos capazes de causar hepatites virais. Independentemente do tipo de hepatite viral, as alteracoes hepaticas podem estar presentes no paciente e representar disturbios funcionais importantes. O cirurgiao-dentista deve estar apto a tratar o paciente hepatopata, sendo capaz de avaliar as alteracoes sistemicas relacionadas ao mau funcionamento do orgao. (AU)
Guanabara Koogan eBooks, 2015
2016 24th Mediterranean Conference on Control and Automation (MED), 2016
The paper presents experimental results related to attitude control of a quadrotor rotating about... more The paper presents experimental results related to attitude control of a quadrotor rotating about a single axis. The Embedded Model Control (EMC) methodology is used for control design. Indeed, this methodology can be very effective in applications involving relevant disturbances, modeling errors and unknown nonlinearities, since it allows a cancellation of all these sources of uncertainty. EMC control design is performed from a detailed quadrotor model, where the actuator dynamics is identified from experimental data. The designed EMC controller is compared with a standard proportionalintegral-derivative (PID) controller in several tests, carried out on a laboratory testbench.
Brazilian Oral Research, 2011
We realized immunohistochemical procedures with p16 and Ki-67 in lesions of oral lichen planus to... more We realized immunohistochemical procedures with p16 and Ki-67 in lesions of oral lichen planus to verify the presence and kind of its immunoexpression amog the two groups of patients, asymptomatic and symptomatic, correlating the clinical and histopathological diagnosis with the immunohistochemical data in order to verify if oral lichen planus can be considered a lesion with risk of malignant transformation. MATERIAL AND METHOD: nine asymptomatic patients and 12 symptomatic of oral lichen planus. Five cases of inflammattory fibrous hyperplasia were included as control group. For immunohistochemical studies we used p16 (prediluted-BioSB/USA) and Ki-67 (clone MIB-1-DAKO/USA) by Envision Labelled techniques (DAKO). Results were annalyzed according to parameters based on Klaes et al. (2001) evaluating the immunomarked cell rates, the distribution through the epithelial layer and the immunoexpression intensity. The statistics analysis proceeded the study of relative risk between asymptomatic and symptomatic patients regarding to its cellular immunoexpression (nuclear, cytoplasmic or both), the more prevalent topography of the lesion (buccal mucosa and tongue) and clinical characteristics (atrophic and reticular types). RESULTS: the correlation between asymptomatic and symptomatic patients was statistically significant (p<0.05) when comparison was made of the distribution of p16 throug the epithelial layer by analysis its cellular imumunoexpression. The nuclear immunoexpression of p16 showed an odds ratio of 4.091. The nuclear and cytoplasmatic were 5.179. The odds ratio for cytoplasmatic expression was 8.461. The correlation between immunoexpression and topography resulted in an odds ratio of 5.130 for tongue and 14.234 for buccal mucosa. The other categories availed as percentage and intensity of the p16 immunoexpression, clinical characteristics, besides the Ki-67 results gave non significant results. CONCLUSIONS: The citoplasmatic expression results indicates that this immunoexpression must not be discarded, as suggested by some studies. The high relative risk saw in buccal mucosa rather than tongue was an unexpected result, because the localization pointed as with greater involvement in cases of malignat transformation is the tongue. The distribution was the only one that reached a statistically significant result, so further studies must be made in order to include or exclude the human papillomavirus presence in oral lichen planus lesions, since the p16 protein is currently nowadays used as an indicator of cellular abnormalities in cervical lesions, where its overexpression is related to the presence of high risk human papillomavirus, beyond study of p16 in the cases of liquenoid dysplasia.
Os problemas da cavidade bucal muitas vezes podem repercutir na vida social de um paciente, influ... more Os problemas da cavidade bucal muitas vezes podem repercutir na vida social de um paciente, influenciando sobremaneira negativamente na autoestima e autoconfianca. Esses fatores merecem especial atencao quando passam a ser usados como forma de assedio moral horizontal ou bullying, principalmente quando praticado de modo velado atras dos muros de escolas entre criancas e adolescentes. A clinica de odontopediatria da UnG alem de promover saude, alcanca a inclusao social de potenciais vitimas dos problemas em questao, uma vez que neutraliza e corrige as enfermidades ora utilizadas como armas de terror psicologico. O presente trabalho visa apresentar um caso clinico da disciplina de odontopediatria para reabilitacao funcional, fonetica e estetica que proporcionou ao paciente uma ressocializacao, comprovada por testemunho do proprio beneficiado, de familiares e de conhecidos que o acompanhavam durante os procedimentos clinicos. A presente observacao, tambem, ratifica o imprescindivel papel da odontologia, em associacao a outras especialidades da area da saude, como membro de uma equipe multidisciplinar voltada a resolucao de questoes atuais e que afligem nao apenas o complexo estomatognatico mas tambem o psicossomatico.
Comun. ciênc. …, 2006
... Autor: Toledo, Maria Fernanda; Rode, Sigmar de Mello; Lemos Júnior, Celso Augusto; Basile, An... more ... Autor: Toledo, Maria Fernanda; Rode, Sigmar de Mello; Lemos Júnior, Celso Augusto; Basile, Ana Paula; Lotufo, Mônica Andrade. Título: Manifestações clínicas intrabucais da doença de Crohn û Relato de caso clínico / Oral manifestation in Crohn's Disease − Case report. ...
SciELO Brasil
As you are well aware of, the International Association ... Through its Divisions, the IADR offer... more As you are well aware of, the International Association ... Through its Divisions, the IADR offers a set of opportunities for dental researchers in these countries: building networks with other researchers; developing contacts in a close geographical environment; attending annual ...
SciELO Brasil
The changes in modern society caused by the Internet are immeasurable. Great transformations in t... more The changes in modern society caused by the Internet are immeasurable. Great transformations in the global world have clearly influenced the educational process and knowledge acquisition. Therefore, the search for solutions in order to keep up with the incalculable ...
SciELO Brasil
The roles of any researcher are to make public scientific findings, spread the knowledge and cont... more The roles of any researcher are to make public scientific findings, spread the knowledge and contribute to the construction of a better Dentistry. Many are the difficulties, among them is managing articles to appear in renowned publications because there are only a few qualified ...
SciELO Brasil
According to the Helsinki Declaration, adopted by the 18th World Medical Assembly in Helsinki, Fi... more According to the Helsinki Declaration, adopted by the 18th World Medical Assembly in Helsinki, Finland (1964), the first item of the Basic Principles states that Biomedical research involving human subjects must conform to generally accepted scientific principles and ...
Rev. Assoc. Paul. Cir. Dent, 2005
O figado pode ser afetado por agentes quimicos, fisicos ou biologicos. Atualmente, aceita-se a ex... more O figado pode ser afetado por agentes quimicos, fisicos ou biologicos. Atualmente, aceita-se a existencia de 9 virus hepatotropicos capazes de causar hepatites virais. Independentemente do tipo de hepatite viral, as alteracoes hepaticas podem estar presentes no paciente e representar disturbios funcionais importantes. O cirurgiao-dentista deve estar apto a tratar o paciente hepatopata, sendo capaz de avaliar as alteracoes sistemicas relacionadas ao mau funcionamento do orgao. (AU)
Guanabara Koogan eBooks, 2015
2016 24th Mediterranean Conference on Control and Automation (MED), 2016
The paper presents experimental results related to attitude control of a quadrotor rotating about... more The paper presents experimental results related to attitude control of a quadrotor rotating about a single axis. The Embedded Model Control (EMC) methodology is used for control design. Indeed, this methodology can be very effective in applications involving relevant disturbances, modeling errors and unknown nonlinearities, since it allows a cancellation of all these sources of uncertainty. EMC control design is performed from a detailed quadrotor model, where the actuator dynamics is identified from experimental data. The designed EMC controller is compared with a standard proportionalintegral-derivative (PID) controller in several tests, carried out on a laboratory testbench.
Brazilian Oral Research, 2011
We realized immunohistochemical procedures with p16 and Ki-67 in lesions of oral lichen planus to... more We realized immunohistochemical procedures with p16 and Ki-67 in lesions of oral lichen planus to verify the presence and kind of its immunoexpression amog the two groups of patients, asymptomatic and symptomatic, correlating the clinical and histopathological diagnosis with the immunohistochemical data in order to verify if oral lichen planus can be considered a lesion with risk of malignant transformation. MATERIAL AND METHOD: nine asymptomatic patients and 12 symptomatic of oral lichen planus. Five cases of inflammattory fibrous hyperplasia were included as control group. For immunohistochemical studies we used p16 (prediluted-BioSB/USA) and Ki-67 (clone MIB-1-DAKO/USA) by Envision Labelled techniques (DAKO). Results were annalyzed according to parameters based on Klaes et al. (2001) evaluating the immunomarked cell rates, the distribution through the epithelial layer and the immunoexpression intensity. The statistics analysis proceeded the study of relative risk between asymptomatic and symptomatic patients regarding to its cellular immunoexpression (nuclear, cytoplasmic or both), the more prevalent topography of the lesion (buccal mucosa and tongue) and clinical characteristics (atrophic and reticular types). RESULTS: the correlation between asymptomatic and symptomatic patients was statistically significant (p<0.05) when comparison was made of the distribution of p16 throug the epithelial layer by analysis its cellular imumunoexpression. The nuclear immunoexpression of p16 showed an odds ratio of 4.091. The nuclear and cytoplasmatic were 5.179. The odds ratio for cytoplasmatic expression was 8.461. The correlation between immunoexpression and topography resulted in an odds ratio of 5.130 for tongue and 14.234 for buccal mucosa. The other categories availed as percentage and intensity of the p16 immunoexpression, clinical characteristics, besides the Ki-67 results gave non significant results. CONCLUSIONS: The citoplasmatic expression results indicates that this immunoexpression must not be discarded, as suggested by some studies. The high relative risk saw in buccal mucosa rather than tongue was an unexpected result, because the localization pointed as with greater involvement in cases of malignat transformation is the tongue. The distribution was the only one that reached a statistically significant result, so further studies must be made in order to include or exclude the human papillomavirus presence in oral lichen planus lesions, since the p16 protein is currently nowadays used as an indicator of cellular abnormalities in cervical lesions, where its overexpression is related to the presence of high risk human papillomavirus, beyond study of p16 in the cases of liquenoid dysplasia.
Os problemas da cavidade bucal muitas vezes podem repercutir na vida social de um paciente, influ... more Os problemas da cavidade bucal muitas vezes podem repercutir na vida social de um paciente, influenciando sobremaneira negativamente na autoestima e autoconfianca. Esses fatores merecem especial atencao quando passam a ser usados como forma de assedio moral horizontal ou bullying, principalmente quando praticado de modo velado atras dos muros de escolas entre criancas e adolescentes. A clinica de odontopediatria da UnG alem de promover saude, alcanca a inclusao social de potenciais vitimas dos problemas em questao, uma vez que neutraliza e corrige as enfermidades ora utilizadas como armas de terror psicologico. O presente trabalho visa apresentar um caso clinico da disciplina de odontopediatria para reabilitacao funcional, fonetica e estetica que proporcionou ao paciente uma ressocializacao, comprovada por testemunho do proprio beneficiado, de familiares e de conhecidos que o acompanhavam durante os procedimentos clinicos. A presente observacao, tambem, ratifica o imprescindivel papel da odontologia, em associacao a outras especialidades da area da saude, como membro de uma equipe multidisciplinar voltada a resolucao de questoes atuais e que afligem nao apenas o complexo estomatognatico mas tambem o psicossomatico.
Comun. ciênc. …, 2006
... Autor: Toledo, Maria Fernanda; Rode, Sigmar de Mello; Lemos Júnior, Celso Augusto; Basile, An... more ... Autor: Toledo, Maria Fernanda; Rode, Sigmar de Mello; Lemos Júnior, Celso Augusto; Basile, Ana Paula; Lotufo, Mônica Andrade. Título: Manifestações clínicas intrabucais da doença de Crohn û Relato de caso clínico / Oral manifestation in Crohn's Disease − Case report. ...
SciELO Brasil
As you are well aware of, the International Association ... Through its Divisions, the IADR offer... more As you are well aware of, the International Association ... Through its Divisions, the IADR offers a set of opportunities for dental researchers in these countries: building networks with other researchers; developing contacts in a close geographical environment; attending annual ...
SciELO Brasil
The changes in modern society caused by the Internet are immeasurable. Great transformations in t... more The changes in modern society caused by the Internet are immeasurable. Great transformations in the global world have clearly influenced the educational process and knowledge acquisition. Therefore, the search for solutions in order to keep up with the incalculable ...
SciELO Brasil
The roles of any researcher are to make public scientific findings, spread the knowledge and cont... more The roles of any researcher are to make public scientific findings, spread the knowledge and contribute to the construction of a better Dentistry. Many are the difficulties, among them is managing articles to appear in renowned publications because there are only a few qualified ...
SciELO Brasil
According to the Helsinki Declaration, adopted by the 18th World Medical Assembly in Helsinki, Fi... more According to the Helsinki Declaration, adopted by the 18th World Medical Assembly in Helsinki, Finland (1964), the first item of the Basic Principles states that Biomedical research involving human subjects must conform to generally accepted scientific principles and ...