M. Garry - Academia.edu (original) (raw)

Papers by M. Garry

Human Movement Science, 1997

... deviations from a smooth acceleration profile, van Donkelaar and Franks (l991a) also performe... more ... deviations from a smooth acceleration profile, van Donkelaar and Franks (l991a) also performed a harmonic analysis on the acceleration profiles of the horizontal repetitive arm extensionflexion movements (see Van Galen et al., 1990, and van Donkelaar and Franks, l991a, for ...

Circulation Research, 2008

Stem and progenitor cell populations occupy a specialized niche and are consequently exposed to h... more Stem and progenitor cell populations occupy a specialized niche and are consequently exposed to hypoxic as well as oxidative stresses. We have previously established that the multidrug resistance protein Abcg2 is the molecular determinant of the side population (SP) progenitor cell population. We observed that the cardiac SP cells increase in number more than 3-fold within 3 days of injury. Transcriptome analysis of the SP cells isolated from the injured adult murine heart reveals increased expression of cytoprotective transcripts. Overexpression of Abcg2 results in an increased ability to consume hydrogen peroxide and is associated with increased levels of ␣-glutathione reductase protein expression. Importantly, overexpression of Abcg2 also conferred a cell survival benefit following exposure to hydrogen peroxide. To further examine the molecular regulation of the Abcg2 gene, we demonstrated that hypoxia-inducible factor (HIF)-2␣ binds an evolutionary conserved HIF-2␣ response element in the murine Abcg2 promoter. Transcriptional assays reveal a dose-dependent activation of Abcg2 expression by HIF-2␣. These results support the hypothesis that Abcg2 is a direct downstream target of HIF-2␣ which functions with other factors to initiate a cytoprotective program for this progenitor SP cell population that resides in the adult heart. (Circ Res. 2008;102:1075-1081.)

Applied Cognitive Psychology, 2011

Acta Psychologica, 2012

Are claims more credible when made by multiple sources, or is it the repetition of claims that ma... more Are claims more credible when made by multiple sources, or is it the repetition of claims that matters? Some research suggests that claims have more credibility when independent sources make them. Yet, other research suggests that simply repeating information makes it more accessible and encourages reliance on automatic processes-factors known to change people's judgments. In Experiment 1, people took part in a "misinformation" study: people first watched a video of a crime and later read eyewitness reports attributed to one or three different eyewitnesses who made misleading claims in either one report or repeated the same misleading claims across all three reports. In Experiment 2, people who had not seen any videos read those same reports and indicated how confident they were that each claim happened in the original event. People were more misled by-and more confident about-claims that were repeated, regardless of how many eyewitnesses made them. We hypothesize that people interpreted the familiarity of repeated claims as markers of accuracy. These findings fit with research showing that repeating information makes it seem more true, and highlight the power of a single repeated voice.

International Journal of Obstetric Anesthesia, 2009

We report a case of a patient with congenital aortic stenosis previously repaired using the Ross ... more We report a case of a patient with congenital aortic stenosis previously repaired using the Ross procedure, who presented to our unit for urgent caesarean delivery. Management was complicated by moderate residual cardiac disease and the presence of a suprapubic femoro-femoral crossover graft. Following application of five-lead electrocardiogram and invasive blood pressure monitoring, anaesthesia was induced via combined spinal-epidural with epidural volume extension. A high transverse surgical approach avoided the course of the vascular graft, while further precautions included the immediate availability of vascular surgeons and cell salvage. Our anaesthetic technique was tailored to minimise disruption to cardiovascular function, and in particular to limit regurgitant flow across the pulmonary valve. This case highlights the value of early identification of high-risk parturients and multidisciplinary involvement at delivery. Risk stratification in the patient with grown-up congenital heart disease is based upon timely evaluation of the underlying congenital pathology, surgical history and subsequent functional status.

International journal of obstetric anesthesia, 2009

Journal of endodontics, 1992

Neuropeptides such as calcitonin gene-related peptide (CGRP) and substance P are present in denta... more Neuropeptides such as calcitonin gene-related peptide (CGRP) and substance P are present in dental pulp in relatively high concentrations. Previous studies have demonstrated that the staining density of immunoreactive CGRP (iCGRP) changes in dental pulp after tissue injury. This study evaluated injury-related changes in levels of both immunoreactive CGRP (iCGRP) and immunoreactive substance P (iSP) in dental pulp using radioimmunoassays. After pulpal exposure, iSP levels decreased to about 10% of baseline values, while iCGRP levels decreased to about 45% of baseline measures. After dentin exposure with acid etch, iSP levels decreased to about 10 to 20% of baseline measures, while iCGRP levels decreased to 60% of baseline values. For both forms of injury, iSP decreased to a greater extent than did iCGRP levels. Collectively, these findings indicate that pulpal neuropeptides undergo dynamic, injury-specific, and peptide-specific responses following trauma to dental pulp.

Psychological Science, 2004

Some trauma-memory-oriented psychotherapists advise clients to review old family photo albums to ... more Some trauma-memory-oriented psychotherapists advise clients to review old family photo albums to cue suspected "repressed" memories of childhood sexual abuse. Old photos might cue long-forgotten memories, but when combined with other suggestive influences they might also contribute to false memories. We asked 45 undergraduates to work at remembering three schoolrelated childhood events (two true events provided by parents and one pseudoevent). By random assignment, 23 subjects were also given their school class group photos from the years of the to-be-recalled events as memory cues. As predicted, the rate of false-memory reports was dramatically higher in the photo condition than in the no-photo condition. Indeed, the rate of falsememory reports in the photo condition was substantially higher than that of any previously published study.

Psychology of Consciousness: Theory, Research, and Practice, 2014

Do you have many regrets from last year? To answer that question, you might start searching your ... more Do you have many regrets from last year? To answer that question, you might start searching your memory and accumulating evidence. But your answer might not depend on how many regrets you remember. Instead, it might depend on how easy it feels to remember them. People often think that they have a larger pool of experiences to sample from when remembering feels easy than when remembering feels difficult. Thus, the relative ease of remembering can give us a quick indication of how many experiences we have had. Do people also rely on this feeling when thinking about their regrets? Across 3 experiments, we asked people to remember easy or difficult numbers of regrets from the past year, and then to rate how much regret they had for that year. Contrary to our predictions and the literature, we found that people relied on both number and ease: after remembering a small but easy number of regretted experiences, they rated the past year as less full of regret than others who remembered a large but difficult number. This pattern of results remained even when we drew people's attention to the ease or difficulty of remembering. These results add nuance to the published literature, and suggest that when we think about how many regrets we have, what matters most is quantity and missed opportunity.