MOHAMED ALFERJANI - Academia.edu (original) (raw)

Papers by MOHAMED ALFERJANI

Scholars journal of applied medical sciences, Jan 24, 2022

Original Research Article This research aims to study the causes of neonatal admissions and death... more Original Research Article This research aims to study the causes of neonatal admissions and deaths among newborns at neonate department in Benghazi Children Hospital. A cross sectional retrospective study was conducted during 2019. Data included; causes of admission, causes of deaths, gender, age, residency, area of referral, duration of hospital stay. Out of 1720 neonatal admissions reviewed, the total number of deaths was 229, the overall mortality rate was (13.3%) but much higher (25.2%) among the referred babies. The male gender was predominant admissions and deaths (61.3% and 63% respectively). Most of neonatal admissions and deaths were occurred in the first week of life. The most frequent cause of admission was neonatal jaundice 492 (28.6%) followed by RD 380 (22.1%). The common cause of death was prematurity and its related problems 66 (28.3%), then neonatal sepsis 51 (22.3%) and congenital heart disease 36(15.7%).

SAS journal of medicine, Feb 11, 2023

Original Research Article Background: Respiratory distress (RD) is a common problem in newborns i... more Original Research Article Background: Respiratory distress (RD) is a common problem in newborns immediately following birth. It is often seen during the transition from fetal to neonatal life. Aims: This study was conducted to demonstrate the surgical causes of respiratory distress in infants admitted to paediatric surgical department of Benghazi Children Hospital and to describe the short term outcome of the sample. Methodology: A retrospective observational descriptive cross section study was done to achieve the aims of this study. Results: A sample of (50) children admitted with respiratory distress due to congenital anomalies, the age range of the sample was from one day to one year, male were (70%) and females and (30%). Residency (20%) from Benghazi and (80%) from outside Benghazi. Normal delivery was reported in52% of the cases and (48%) C/S, (86%) were born at term and (14%) preterm. The mean weight of the cases was (3.38) (±1.91) kg with minimum of (2) kg and maximum (10) kg. TOF in (52%), diaphragmatic hernia in (40%) and lung emphysema in (8%). Clinical presentation of the cases was mainly with respiratory distress in (84%), while (16%) presented with frothy secretion, ultrasound scan was done to (88%) and was normal. Echocardiogram was normal, atrial septal defect in (16%), ventricular septal defect in (14%), patent ductus arteriosus in (8%). (80%) were operated. Death was recorded in half of the cases. Cases with TOF were in total (26) cases of them (17) died and (9) survived, diaphragmatic hernia cases were (20), of them (12) discharged and (8) died, all cases of congenital lobar emphysema discharged. This association was highly significant Fisher`s (exact=6.9 P=0.005). all preterm neonate died (seven cases) and those who were term were in total (43) of them (25) survived and (18) died, Fisher`s (exact=10.85 P=0.005). Cases who were presented with respiratory distress were in total (42) of them (18) died and (25) discharged, while cases who presented with frothy secretions were in total (8) of them (7) died. Fisher`s (exact=5.4 P=0.022). cases with normal echo were (25) cases of them (19) discharged and only (6) died, cases with ASD were (8) of them 6 died, (7) cases with VSD all of them died, PDA associated with good outcome as they were four cases all of them discharged, and echo was not done to (6) cases and all of them had died Fisher`s (exact=25.6 P=0.001). Operation for congenital anomalies was done to (40) cases of them (16) died and (24) discharged, and not done to (10) cases of them (9) died and one case discharged. This association was with highly statistical significance. Fisher`s (exact=8, P=0.005). Conclusion: RD in neonate was more common in male than female; cases from outside Benghazi were more frequent. Predicting cases outcome was not based on variables such as gender, mode of delivery, city of residence which showed no significant association with cases outcome. Poor outcome predictors of the current study were diagnosis, birth maturity, clinical presentation, ECHO results.

Scholars journal of applied medical sciences, Sep 9, 2020

Original Research Article Vitamin D is known to play an important role in bone metabolism and imm... more Original Research Article Vitamin D is known to play an important role in bone metabolism and immune system regulation. Objective: to evaluate the impact of maternal vitamin D level on Baby hematological & anthropometric measurements. Patients and methods: prospective cross sectional study was conducted on 22 women with their babies who delivered vaginally at AL-Jamhoria hospital labour room with gestational age ˃ 37 week. The verbal consent was taken with Full out the questions Form. Maternal venous blood for biochemical (vitamin D, PTH, s. Ca+, s. Po4, s. Alk. Ph) & baby venous blood for biochemical (vit. D, s.Ca+, s. PO4, s. Alk. Ph) and anthropometric measurements (B. weight, Length, Head circumference) were taken immediately after birth by same person. Results and Conclusion: 22 women with their babies, aged between 19-42 year with mean (31.5± 5.83) where 5 (22.7 %) 0f them received vitamin D injection during pregnancy. Mean maternal vitamin D & parathyroid hormone levels were (3.29± 1.36 & 53.2± 2.2) respectively, the mean maternal calcium, phosphate & Alkaline phosphatase were {(8.5± 0.42), (3.66± 0.46), (77.5± 2.2)} respectively. The mean baby vitamin D level is 3.75± 2.04 where10 (45.5%) of babies had features of vitamin D. The mean baby calcium, phosphate, Alkaline phosphatase were {(9.20± 0.56), (5.20± 0.7), (93.5± 3.20)} respectively. The mean baby birth weight, Length, Head circumference were {(3.35± 0.45), (49.95± 1.17), (34.79± 1.08)} respectively. The significant correlation were exists between Maternal vitamin D & baby vitamin D & between Maternal parathyroid hormone & Baby Alkaline phosphatase.

Asian Journal of Pediatric Research

Patients undergoing chemotherapy are vulnerable to infection because of immunosuppression and pro... more Patients undergoing chemotherapy are vulnerable to infection because of immunosuppression and prolonged hospitalizations. Chemotherapy drugs affect neutrophil production through myelosuppression (1) and low inflammatory response so that fever maybe the manifestation of infection (2). The purpose of this study was to analyze febrile neutropenic episodes associated with infections in the 1st three phases of acute lymphoblastic leukemia (ALL) treatment, document the risk factors affecting morbidity, mortality, treatment and the outcome of treatment. The study was a cross-sectional hospital-based descriptive survey in the Hematology-Oncology Unit at Children’s Hospital. It included all cases of (ALL) who were diagnosed within two years and treated with the Berlin Frankfurt Munich (BFM) protocol who developed fever during a neutropenic period. Data was recorded as gender, age, residence, nationality, number of episodes per patient, treatment phase, admission duration, length of stay (LOS...

SAS Journal of Medicine

Background: Respiratory distress (RD) is a common problem in newborns immediately following birth... more Background: Respiratory distress (RD) is a common problem in newborns immediately following birth. It is often seen during the transition from fetal to neonatal life. Aims: This study was conducted to demonstrate the surgical causes of respiratory distress in infants admitted to paediatric surgical department of Benghazi Children Hospital and to describe the short term outcome of the sample. Methodology: A retrospective observational descriptive cross section study was done to achieve the aims of this study. Results: A sample of (50) children admitted with respiratory distress due to congenital anomalies, the age range of the sample was from one day to one year, male were (70%) and females and (30%). Residency (20%) from Benghazi and (80%) from outside Benghazi. Normal delivery was reported in52% of the cases and (48%) C/S, (86%) were born at term and (14%) preterm. The mean weight of the cases was (3.38) (±1.91) kg with minimum of (2) kg and maximum (10) kg. TOF in (52%), diaphragm...

Scholars Journal of Applied Medical Sciences

Rickets occurs when growing bones fail to mineralize. In most cases, the diagnosis is done basing... more Rickets occurs when growing bones fail to mineralize. In most cases, the diagnosis is done basing on clinical examination, laboratory testing and radiological imaging. Aims: this study aimed to investigate demographic and clinical profile of children diagnosed with Rickets and to assess the treatment outcome. Subjects and method: a comparative follow-up observational survey was conducted by collecting the data from a sample at two points of time, prior to treatment and 6 months after treatment, the sample was purposive, contact details of mothers of the children were kept to assure the 2nd meeting of data collection. Results: a sample of 153 child was studied, more than 97% of them aged between 1-2 years with mean age of 13.6 months (± 5.99), 53% of them males, 94.8 from Benghazi.62% were early weaned and 58.8 % eat family diet. At presentation the children were found to have delayed walking (17%), failure to thrive (15.7%), lethargy (13.7%), delayed teething (10.5%), rachitic rosar...

Scholars Journal of Applied Medical Sciences, 2022

This research aims to study the causes of neonatal admissions and deaths among newborns at neonat... more This research aims to study the causes of neonatal admissions and deaths among newborns at neonate department in Benghazi Children Hospital. A cross sectional retrospective study was conducted during 2019. Data included; causes of admission, causes of deaths, gender, age, residency, area of referral, duration of hospital stay. Out of 1720 neonatal admissions reviewed, the total number of deaths was 229, the overall mortality rate was (13.3%) but much higher (25.2%) among the referred babies. The male gender was predominant admissions and deaths (61.3% and 63% respectively). Most of neonatal admissions and deaths were occurred in the first week of life. The most frequent cause of admission was neonatal jaundice 492 (28.6%) followed by RD 380 (22.1%). The common cause of death was prematurity and its related problems 66 (28.3%), then neonatal sepsis 51 (22.3%) and congenital heart disease 36(15.7%).

BMC Pediatrics, 2020

Background Neonatal mortality remains a serious global public health problem, but Sub-Saharan Afr... more Background Neonatal mortality remains a serious global public health problem, but Sub-Saharan Africa (SSA), in particular, is largely affected. Current evidence on neonatal mortality is essential to inform programs and policies, yet there is a scarcity of information concerning neonatal mortality in our study area. Therefore, we conducted this prospective cohort study to determine the incidence and predictors of neonatal mortality at Debre Markos Referral Hospital, Northwest Ethiopia. Methods This institutionally-based prospective cohort study was undertaken among 513 neonates admitted to the neonatal intensive care unit of Debre Markos Referral Hospital between December 1st, 2017 and May 30th, 2018. All newborns consecutively admitted to the neonatal intensive care unit during the study period were included. An interviewer administered a questionnaire with the respective mothers. Data were entered using Epi-data™ Version 3.1 and analyzed using STATA™ Version 14. The neonatal surviv...

JAMA: The Journal of the American Medical Association, 1977

THROMBOCYTOPENIC purpura has been reported secondary to a multiplicity of causes. 1 However, idio... more THROMBOCYTOPENIC purpura has been reported secondary to a multiplicity of causes. 1 However, idiopathic thrombocytopenic purpura (ITP), in relation to infectious diseases other than viral illnesses, is unusual. We report two cases where ITP developed with the onset of histoplasmosis. Report of Cases Case 1.— A 41-year-old woman was referred to the University of Iowa Hospitals on July 3, 1970, with a two-week history of fevers, chills, headache, nonproductive cough, and a 7-kg weight loss. She had failed to respond to oral antibiotic therapy. She had been in good health prior to the onset of the aforementioned symptoms, and there was no antecedent history of easy bleeding, bruising, or hematologic abnormality. The patient appeared severely ill and was febrile. Neither lymphadenopathy nor hepatosplenomegaly was found. Pulmonary and cardiovascular examination results were unremarkable. Petechiae and ecchymoses were not observed. Initial laboratory studies included a WBC count of 7,400/cu mm, with 81%

Scholars Journal of Applied Medical Sciences, 2020