MUSTAPHA FAROUK - Academia.edu (original) (raw)

Papers by MUSTAPHA FAROUK

Research paper thumbnail of The PRIMARA study: a prospective, descriptive, observational study to review cinacalcet use in patients with primary hyperparathyroidism in clinical practice

European Journal of Endocrinology, 2014

ObjectiveMedical management of primary hyperparathyroidism (PHPT) is important in patients for wh... more ObjectiveMedical management of primary hyperparathyroidism (PHPT) is important in patients for whom surgery is inappropriate. We aimed to describe clinical profiles of adults with PHPT receiving cinacalcet.DesignA descriptive, prospective, observational study in hospital and specialist care centres.MethodsFor patients with PHPT, aged 23–92 years, starting cinacalcet treatment for the first time, information was collected on dosing pattern, biochemistry and adverse drug reactions (ADRs). Initial cinacalcet dosage and subsequent dose changes were at the investigator's discretion.ResultsOf 303 evaluable patients with PHPT, 134 (44%) had symptoms at diagnosis (mostly bone pain (58) or renal stones (50)). Mean albumin-corrected serum calcium (ACSC) at baseline was 11.4 mg/dl (2.9 mmol/l). The reasons for prescribing cinacalcet included: surgery deemed inappropriate (35%), patient declined surgery (28%) and surgery failed or contraindicated (22%). Mean cinacalcet dose was 43.9 mg/day ...

Research paper thumbnail of An observational cohort study of extended dosing (once every 2 weeks or once monthly) regimens with darbepoetin alfa in patients with chronic kidney disease not on …

Nephrology Dialysis …, 2011

Background. Darbepoetin alfa (DA) has been shown to be an effective treatment of anaemia in patie... more Background. Darbepoetin alfa (DA) has been shown to be an effective treatment of anaemia in patients with chronic kidney disease (CKD) not on dialysis (NoD). EXTEND is an observational study assessing the effectiveness of DA administered once biweekly (Q2W) ...

Research paper thumbnail of Cholecystectomy versus no cholecystectomy for gallbladder polyp

The Cochrane Library

... trials, which compare cholecystectomy (open or laparoscopic) versus no cholecystec-tomy (irre... more ... trials, which compare cholecystectomy (open or laparoscopic) versus no cholecystec-tomy (irrespective of language, blinding, publication status, sam-ple size ... Gurusamy 2006 Gurusamy KS, Samraj K. Early versus delayed laparoscopic chole-cystectomy for acute cholecystitis. ...

Research paper thumbnail of Semantic structure content for dynamic web pages

Semantic Technology and Information …, 2011

Representing web data into a machine understandable format is a curtail task for the next generat... more Representing web data into a machine understandable format is a curtail task for the next generation of the web. Most of solutions are relying on ontologies. However, there are many problems of using ontologies. This paper proposes an approach to represent dynamic web page contents retrieved from underlying database, into Concept Description Language (CDL) semantic format. This format does not depend on ontologies. However, CDL describes semantic structure of web content based on a set of predefined concepts and semantic relations. A prototype of the proposed approach is implemented to show visibility of the proposed approach.

Research paper thumbnail of Facile synthesis of 3-substituted quinazoline-2,4-dione and 2,3-di-substituted quinazolinone derivatives

Chemical Papers, 2013

3-Substituted quinazoline-2,4(1H,3H)-dione and 2,3-di-substituted quinazolineone derivatives attr... more 3-Substituted quinazoline-2,4(1H,3H)-dione and 2,3-di-substituted quinazolineone derivatives attract considerable interest due to their pharmacological properties. In this paper, we report the synthesis of N-substituted-3-nitrophthalimide derivatives II–III, the reactions of phthalimide III with amines, hydrazines, and amino acid derivatives to synthesise a small library of 3-substituted-5-nitroquinazoline-2,4(1H,3H)-diones IV–XIV and 2,3-di-substituted-6-nitro-quinazolineones XVIII–XIX.

Research paper thumbnail of The assessment of the proximate composition, mineral composition and nutritive value of two edible mushroom genera

aun.edu.eg

2-EFFSCT Of TWO MUSHROQM VARIETIES INTAKE ON SCRUM TWGLYCSRWES, CHOlEWEKOi FRACTIONS AND SERUM GL... more 2-EFFSCT Of TWO MUSHROQM VARIETIES INTAKE ON SCRUM TWGLYCSRWES, CHOlEWEKOi FRACTIONS AND SERUM GLUCOSE LEVELS IN A. LBINO RATS, M. Kamal E. Youssef, Farouk, M. El-Tellcnvy"* Amany Osama and Hlend, MA Mol mined, مجلة ...

Research paper thumbnail of Prospective study of hepatobiliary scintigraphy and endoscopic cholangiography for the detection of early biliary complications after orthotopic liver transplantation

British Journal of Surgery, 1997

Background Biliary complications are a significant cause of morbidity and death after orthotopic ... more Background Biliary complications are a significant cause of morbidity and death after orthotopic liver transplantation (OLT). This study was a prospective evaluation of endoscopic retrograde cholangiography (ERC) and hepatobiliary scintigraphy (HBS), using ""Tc Mebrofenin, to detect early biliary complications following OLT.

Research paper thumbnail of Intra-arterial injection of oral medication in HIV positive drug addicts

British Journal of Surgery, 1990

Infected false femoral aneurysms: G. H. Welch et al. publish the clinical details. We are especia... more Infected false femoral aneurysms: G. H. Welch et al. publish the clinical details. We are especially grateful to Mr D. P. Lieberman for his critical advice. We would also like to thank Mrs Jean Dickson for typing the manuscript.

Research paper thumbnail of Prospective randomized trial of end-to-end versus side-to-side biliary reconstruction after orthotopic liver transplantation

British Journal of Surgery, 1999

Background Biliary reconstruction is the Achilles heel of liver transplantation. Side-to-side ana... more Background Biliary reconstruction is the Achilles heel of liver transplantation. Side-to-side anastomosis of donor and recipient bile duct has been claimed to be superior to end-to-end anastomosis in uncontrolled studies. Methods A total of 100 consecutive patients undergoing orthotopic liver transplantation were randomized after commencement of the transplant procedure to end-to-end or side-to-side anastomosis. No T tube drainage was employed. Endoscopic retrograde cholangiography was performed 2 weeks after transplantation and findings were reported by an experienced endoscopist as normal, leak or stricture. Median follow-up was 53 (range 35–63) months. Results Patient age, sex, the graft preservation time and indication for transplantation were similar in both groups. Sixty patients received end-to-end and 40 side-to-side anastomosis. Ten patients randomized to side-to-side anastomosis had an end-to-end procedure. The total number of biliary complications was similar in both grou...

Research paper thumbnail of Functional stability of frozen normal and high pH beef

Meat Science, 2005

The functional properties of whole, diced or minced high and normal pH beef were determined after... more The functional properties of whole, diced or minced high and normal pH beef were determined after 0, 1, 2, 3 and 7 month’s storage. There was no interaction between pH, degree of comminution and storage time for most of the attributes measured. Regardless of storage time or comminution method, high pH meat had significantly (P<0.001) higher sarcoplasmic protein solubility, water

Research paper thumbnail of Unusual computed tomography findings in a patient presenting with acute abdominal pain

Research paper thumbnail of bin MI (2002). Implementing PS21 in the Singapore Police Force (1995–2001): An evaluation. B. Soc. Sc

Research paper thumbnail of Spectroscopic studies of Sm3+ and Eu3+ co-doped lithium borate glass

Journal of Alloys and …, 2010

... b. a Faculty of Science, Physics Department, Beni-Suif University, Egypt. b Faculty of Scienc... more ... b. a Faculty of Science, Physics Department, Beni-Suif University, Egypt. b Faculty of Science (Boys), Physics Department, Alazhar University, Egypt. c Institute of Physics, University of Tartu, Riia 142, Tartu 51014, Estonia. Received ...

Research paper thumbnail of Transplantation: clinical studies (2)

Research paper thumbnail of Indications for and the Technique of Local Resection of Tumors of the Papilla of Vater

Archives of Surgery, 1991

Page 1. Indications for and the Technique of Local Resection of Tumors of the Papilla of Vater Ma... more Page 1. Indications for and the Technique of Local Resection of Tumors of the Papilla of Vater Marwan Farouk, FRCS; Manolis Niotis, MD; Gene D. Branum, MD; Peter B. Cotton, MD; William C. Meyers, MD \s=b\Local resection ...

Research paper thumbnail of Biliary Response to Glucagon in Humans

Research paper thumbnail of Structural properties of Li-borate glasses doped with Sm3+ and Eu3+ ions

Journal of Alloys and Compounds, 2009

... and [16]. Influence of glass-modifier additions such as Al 2 O 3 , halide or sulphate ions, a... more ... and [16]. Influence of glass-modifier additions such as Al 2 O 3 , halide or sulphate ions, as well as irradiation effects on structural changes related to N 4 = BO 4 /BO 3 ratios have been extensively studied [17] and [18]. It has ...

Research paper thumbnail of WORK SHOP (E)(des) Vercors (aux pieds) 2006 La prise en compte des facteurs affectifs dans les ITS Vers des ITS sensibles…

Les systèmes de tutorat intelligent prennent classiquement en compte les aspects cognitifs de l&#... more Les systèmes de tutorat intelligent prennent classiquement en compte les aspects cognitifs de l'apprenant. Ils peuvent alors suggérer les actions à effectuer, corriger les erreurs, fournir des explications. Les travaux actuels reflètent un interêt croissant pour la prise en compte ...

Research paper thumbnail of Exogenous neuropeptide Y blocks myoelectric activity in the upper gastrointestinal tract of starved dogs: brain neuropeptide Y converts a fasting pattern of myoelectric …

Scandinavian …, 1993

The effect of intracerebroventricular (ICV) neuropeptide Y (NPY) on the migrating motor complex (... more The effect of intracerebroventricular (ICV) neuropeptide Y (NPY) on the migrating motor complex (MMC) was examined in five starved dogs. Myoelectric activity was recorded using gastric, duodenal, and jejunal electrodes. Intragastric pressure was monitored via a gastric fistula, and ICV injections were given through a cerebroventricular guide. Recordings were made with no ICV injection and before and after 250-microliters bolus injections of vehicle as control (0.1% dog serum albumin in saline) or 500 pmol/kg NPY. The mean interval between MMCs was 98 +/- 10 min without ICV injection and 96 +/- 7 min after control solution. After ICV injection of NPY no further MMCs were recorded in any dog, even though the study was continued for a minimum of 3.5 h. Instead, the myoelectric pattern became indistinguishable from that in fed dogs. We conclude that central NPY plays a role in modulation of upper gastrointestinal myoelectric activity. This may reflect a central regulatory role for NPY in the coordination of feeding.

Research paper thumbnail of A multistage hierarchical algorithm for hand shape recognition

This paper represents a multistage hierarchical algorithm for hand shape recognition using princi... more This paper represents a multistage hierarchical algorithm for hand shape recognition using principal component analysis (PCA) as a dimensionality reduction and a feature extraction method. The paper discusses the effect of image blurring to build data manifolds using PCA and the different ways to construct these manifolds. In_order to classify the hand shape of an incoming sign object and to be invariant to linear transformations like translation and rotation, a multistage hierarchical classifier structure is used. Computer generated images for different Irish Sign Language shapes are used in testing. Experimental results are given to show the accuracy and performance of the proposed algorithm. I.

Research paper thumbnail of The PRIMARA study: a prospective, descriptive, observational study to review cinacalcet use in patients with primary hyperparathyroidism in clinical practice

European Journal of Endocrinology, 2014

ObjectiveMedical management of primary hyperparathyroidism (PHPT) is important in patients for wh... more ObjectiveMedical management of primary hyperparathyroidism (PHPT) is important in patients for whom surgery is inappropriate. We aimed to describe clinical profiles of adults with PHPT receiving cinacalcet.DesignA descriptive, prospective, observational study in hospital and specialist care centres.MethodsFor patients with PHPT, aged 23–92 years, starting cinacalcet treatment for the first time, information was collected on dosing pattern, biochemistry and adverse drug reactions (ADRs). Initial cinacalcet dosage and subsequent dose changes were at the investigator's discretion.ResultsOf 303 evaluable patients with PHPT, 134 (44%) had symptoms at diagnosis (mostly bone pain (58) or renal stones (50)). Mean albumin-corrected serum calcium (ACSC) at baseline was 11.4 mg/dl (2.9 mmol/l). The reasons for prescribing cinacalcet included: surgery deemed inappropriate (35%), patient declined surgery (28%) and surgery failed or contraindicated (22%). Mean cinacalcet dose was 43.9 mg/day ...

Research paper thumbnail of An observational cohort study of extended dosing (once every 2 weeks or once monthly) regimens with darbepoetin alfa in patients with chronic kidney disease not on …

Nephrology Dialysis …, 2011

Background. Darbepoetin alfa (DA) has been shown to be an effective treatment of anaemia in patie... more Background. Darbepoetin alfa (DA) has been shown to be an effective treatment of anaemia in patients with chronic kidney disease (CKD) not on dialysis (NoD). EXTEND is an observational study assessing the effectiveness of DA administered once biweekly (Q2W) ...

Research paper thumbnail of Cholecystectomy versus no cholecystectomy for gallbladder polyp

The Cochrane Library

... trials, which compare cholecystectomy (open or laparoscopic) versus no cholecystec-tomy (irre... more ... trials, which compare cholecystectomy (open or laparoscopic) versus no cholecystec-tomy (irrespective of language, blinding, publication status, sam-ple size ... Gurusamy 2006 Gurusamy KS, Samraj K. Early versus delayed laparoscopic chole-cystectomy for acute cholecystitis. ...

Research paper thumbnail of Semantic structure content for dynamic web pages

Semantic Technology and Information …, 2011

Representing web data into a machine understandable format is a curtail task for the next generat... more Representing web data into a machine understandable format is a curtail task for the next generation of the web. Most of solutions are relying on ontologies. However, there are many problems of using ontologies. This paper proposes an approach to represent dynamic web page contents retrieved from underlying database, into Concept Description Language (CDL) semantic format. This format does not depend on ontologies. However, CDL describes semantic structure of web content based on a set of predefined concepts and semantic relations. A prototype of the proposed approach is implemented to show visibility of the proposed approach.

Research paper thumbnail of Facile synthesis of 3-substituted quinazoline-2,4-dione and 2,3-di-substituted quinazolinone derivatives

Chemical Papers, 2013

3-Substituted quinazoline-2,4(1H,3H)-dione and 2,3-di-substituted quinazolineone derivatives attr... more 3-Substituted quinazoline-2,4(1H,3H)-dione and 2,3-di-substituted quinazolineone derivatives attract considerable interest due to their pharmacological properties. In this paper, we report the synthesis of N-substituted-3-nitrophthalimide derivatives II–III, the reactions of phthalimide III with amines, hydrazines, and amino acid derivatives to synthesise a small library of 3-substituted-5-nitroquinazoline-2,4(1H,3H)-diones IV–XIV and 2,3-di-substituted-6-nitro-quinazolineones XVIII–XIX.

Research paper thumbnail of The assessment of the proximate composition, mineral composition and nutritive value of two edible mushroom genera

aun.edu.eg

2-EFFSCT Of TWO MUSHROQM VARIETIES INTAKE ON SCRUM TWGLYCSRWES, CHOlEWEKOi FRACTIONS AND SERUM GL... more 2-EFFSCT Of TWO MUSHROQM VARIETIES INTAKE ON SCRUM TWGLYCSRWES, CHOlEWEKOi FRACTIONS AND SERUM GLUCOSE LEVELS IN A. LBINO RATS, M. Kamal E. Youssef, Farouk, M. El-Tellcnvy"* Amany Osama and Hlend, MA Mol mined, مجلة ...

Research paper thumbnail of Prospective study of hepatobiliary scintigraphy and endoscopic cholangiography for the detection of early biliary complications after orthotopic liver transplantation

British Journal of Surgery, 1997

Background Biliary complications are a significant cause of morbidity and death after orthotopic ... more Background Biliary complications are a significant cause of morbidity and death after orthotopic liver transplantation (OLT). This study was a prospective evaluation of endoscopic retrograde cholangiography (ERC) and hepatobiliary scintigraphy (HBS), using ""Tc Mebrofenin, to detect early biliary complications following OLT.

Research paper thumbnail of Intra-arterial injection of oral medication in HIV positive drug addicts

British Journal of Surgery, 1990

Infected false femoral aneurysms: G. H. Welch et al. publish the clinical details. We are especia... more Infected false femoral aneurysms: G. H. Welch et al. publish the clinical details. We are especially grateful to Mr D. P. Lieberman for his critical advice. We would also like to thank Mrs Jean Dickson for typing the manuscript.

Research paper thumbnail of Prospective randomized trial of end-to-end versus side-to-side biliary reconstruction after orthotopic liver transplantation

British Journal of Surgery, 1999

Background Biliary reconstruction is the Achilles heel of liver transplantation. Side-to-side ana... more Background Biliary reconstruction is the Achilles heel of liver transplantation. Side-to-side anastomosis of donor and recipient bile duct has been claimed to be superior to end-to-end anastomosis in uncontrolled studies. Methods A total of 100 consecutive patients undergoing orthotopic liver transplantation were randomized after commencement of the transplant procedure to end-to-end or side-to-side anastomosis. No T tube drainage was employed. Endoscopic retrograde cholangiography was performed 2 weeks after transplantation and findings were reported by an experienced endoscopist as normal, leak or stricture. Median follow-up was 53 (range 35–63) months. Results Patient age, sex, the graft preservation time and indication for transplantation were similar in both groups. Sixty patients received end-to-end and 40 side-to-side anastomosis. Ten patients randomized to side-to-side anastomosis had an end-to-end procedure. The total number of biliary complications was similar in both grou...

Research paper thumbnail of Functional stability of frozen normal and high pH beef

Meat Science, 2005

The functional properties of whole, diced or minced high and normal pH beef were determined after... more The functional properties of whole, diced or minced high and normal pH beef were determined after 0, 1, 2, 3 and 7 month’s storage. There was no interaction between pH, degree of comminution and storage time for most of the attributes measured. Regardless of storage time or comminution method, high pH meat had significantly (P<0.001) higher sarcoplasmic protein solubility, water

Research paper thumbnail of Unusual computed tomography findings in a patient presenting with acute abdominal pain

Research paper thumbnail of bin MI (2002). Implementing PS21 in the Singapore Police Force (1995–2001): An evaluation. B. Soc. Sc

Research paper thumbnail of Spectroscopic studies of Sm3+ and Eu3+ co-doped lithium borate glass

Journal of Alloys and …, 2010

... b. a Faculty of Science, Physics Department, Beni-Suif University, Egypt. b Faculty of Scienc... more ... b. a Faculty of Science, Physics Department, Beni-Suif University, Egypt. b Faculty of Science (Boys), Physics Department, Alazhar University, Egypt. c Institute of Physics, University of Tartu, Riia 142, Tartu 51014, Estonia. Received ...

Research paper thumbnail of Transplantation: clinical studies (2)

Research paper thumbnail of Indications for and the Technique of Local Resection of Tumors of the Papilla of Vater

Archives of Surgery, 1991

Page 1. Indications for and the Technique of Local Resection of Tumors of the Papilla of Vater Ma... more Page 1. Indications for and the Technique of Local Resection of Tumors of the Papilla of Vater Marwan Farouk, FRCS; Manolis Niotis, MD; Gene D. Branum, MD; Peter B. Cotton, MD; William C. Meyers, MD \s=b\Local resection ...

Research paper thumbnail of Biliary Response to Glucagon in Humans

Research paper thumbnail of Structural properties of Li-borate glasses doped with Sm3+ and Eu3+ ions

Journal of Alloys and Compounds, 2009

... and [16]. Influence of glass-modifier additions such as Al 2 O 3 , halide or sulphate ions, a... more ... and [16]. Influence of glass-modifier additions such as Al 2 O 3 , halide or sulphate ions, as well as irradiation effects on structural changes related to N 4 = BO 4 /BO 3 ratios have been extensively studied [17] and [18]. It has ...

Research paper thumbnail of WORK SHOP (E)(des) Vercors (aux pieds) 2006 La prise en compte des facteurs affectifs dans les ITS Vers des ITS sensibles…

Les systèmes de tutorat intelligent prennent classiquement en compte les aspects cognitifs de l&#... more Les systèmes de tutorat intelligent prennent classiquement en compte les aspects cognitifs de l'apprenant. Ils peuvent alors suggérer les actions à effectuer, corriger les erreurs, fournir des explications. Les travaux actuels reflètent un interêt croissant pour la prise en compte ...

Research paper thumbnail of Exogenous neuropeptide Y blocks myoelectric activity in the upper gastrointestinal tract of starved dogs: brain neuropeptide Y converts a fasting pattern of myoelectric …

Scandinavian …, 1993

The effect of intracerebroventricular (ICV) neuropeptide Y (NPY) on the migrating motor complex (... more The effect of intracerebroventricular (ICV) neuropeptide Y (NPY) on the migrating motor complex (MMC) was examined in five starved dogs. Myoelectric activity was recorded using gastric, duodenal, and jejunal electrodes. Intragastric pressure was monitored via a gastric fistula, and ICV injections were given through a cerebroventricular guide. Recordings were made with no ICV injection and before and after 250-microliters bolus injections of vehicle as control (0.1% dog serum albumin in saline) or 500 pmol/kg NPY. The mean interval between MMCs was 98 +/- 10 min without ICV injection and 96 +/- 7 min after control solution. After ICV injection of NPY no further MMCs were recorded in any dog, even though the study was continued for a minimum of 3.5 h. Instead, the myoelectric pattern became indistinguishable from that in fed dogs. We conclude that central NPY plays a role in modulation of upper gastrointestinal myoelectric activity. This may reflect a central regulatory role for NPY in the coordination of feeding.

Research paper thumbnail of A multistage hierarchical algorithm for hand shape recognition

This paper represents a multistage hierarchical algorithm for hand shape recognition using princi... more This paper represents a multistage hierarchical algorithm for hand shape recognition using principal component analysis (PCA) as a dimensionality reduction and a feature extraction method. The paper discusses the effect of image blurring to build data manifolds using PCA and the different ways to construct these manifolds. In_order to classify the hand shape of an incoming sign object and to be invariant to linear transformations like translation and rotation, a multistage hierarchical classifier structure is used. Computer generated images for different Irish Sign Language shapes are used in testing. Experimental results are given to show the accuracy and performance of the proposed algorithm. I.