Madhabi Baidya - Academia.edu (original) (raw)
Papers by Madhabi Baidya
Dhaka Shishu (Children) Hospital Journal
Background: Pediatric colonoscopy is a safe, sensitive and crucial tool for diagnosing as well as... more Background: Pediatric colonoscopy is a safe, sensitive and crucial tool for diagnosing as well as treating children with lower gastrointestinal diseases. In resource-limited countries like Bangladesh, the practice of pediatric colonoscopy remains rudimentary, lacking in trained professionals and appropriate instrumentation. Objectives: The aim of the study was to find out the indications, common colonoscopic findings along with histopathologic evaluation and immediate post procedure complications of colonoscopy in children. Methods: This was a retrospective study; the records of all the patients whose age was less than 18 years and who underwent colonoscopy from January 2017 to December 2021 were studied. Results: Among the total of 196 children (8.23±4.12), the most common indications were lower gastrointestinal bleeding (LGIB) in 107 (54.6%) patients followed by chronic diarrhea in 33 (16.8%), recurrent abdominal pain (RAP) in 16 (8.2%), follow up Inflammatory bowel diseases (IBD)...
Dhaka Shishu (Children) Hospital Journal
Northern International Medical College Journal
Background: Persistent diarrhea is a known cause of mortality, morbidity, and malnutrition in dev... more Background: Persistent diarrhea is a known cause of mortality, morbidity, and malnutrition in developing countries. With recent improvement of rehydration therapy death due to acute diarrhea has been reduced. Though persistent diarrhea accounts for 2-20% of total diarrhea cases, it accounts for 23-62% of all diarrhea related deaths. Objective: The study was done to identify the risk factors associated with persistent diarrhea in children below 5 years of age. Methods: This prospective observational study was conducted in the department of Pediatric Gastroenterology, Hepatology and Nutrition of Dhaka Shishu hospital from July 2019 to June 2020. It included 50 children with persistent diarrhea age between 1 month to <5 years. Detailed history, examination and appropriate investigations were done for all children. Crude odd ratio was calculated for each risk factor by univariate analysis and adjusted odds ratio was calculated by multivariate logistic regression. Results: Most of the...
Dhaka Shishu, Children, Hospital journal, Dec 11, 2022
Background: Upper gastrointestinal endoscopy is an essential, safe and sensitive investigation fo... more Background: Upper gastrointestinal endoscopy is an essential, safe and sensitive investigation for diagnosing pediatric gastrointestinal diseases. In resource-limited countries like Bangladesh, the practice of pediatric endoscopy remains rudimentary, lacking in trained pediatric endoscopists and appropriate-sized endoscopes. There is limited study on paediatric upper GI endoscopy in our country. Objectives: The aim of the study was to find out the indications, common endoscopic findings and immediate post procedure complication of UGI endoscopy in children. Methods: This is a retrospective study; the records of all the patients whose age is less than 18 years and who underwent endoscopy in the last 6 years were studied. Results: Among the total of 384 children (age <18 years), the most common indications were recurrent abdominal pain in 133 (34.7%) patients followed by hematemesis±melena in 99 (25.8%), esophageal varices (follow up with eradication) in 67 (17.5%), recurrent vomiting in 31 (8.1%), foreign body, CLD screening, suspected celiac disease, isolated splenomegaly, corrosive injury, and weight loss. The most common abnormal findings were gastritis in 103 (26.9%) children followed by esophageal varices in 73 (19.2%), duodenitis in 26 (6.8%), foreign body, esophagitis, hiatus hernia, esophageal stricture, esophageal ulcer, gastric ulcer, duodenal ulcer etc. Minor adverse events occurred in 7.0% of children. Conclusion: The commonest indication for Pediatric UGI endoscopy was recurrent abdominal pain and the commonest endoscopic feature was gastritis. No significant post procedure complication was noted in the study.
Egyptian Liver Journal, Nov 18, 2022
Background: Wilson disease (WD) is an inherited disorder of copper metabolism commonly involving ... more Background: Wilson disease (WD) is an inherited disorder of copper metabolism commonly involving the liver, cornea, and brain. Its incidence is increasing day by day worldwide. Early diagnosis and prompt treatment are the key for best outcome. Material and methods: A cross-sectional descriptive study was done from January 2014 to December 2019. Sixty children of both genders between 3 and 18 years were diagnosed by clinical and laboratory profile meeting selected criteria. Results: Mean age was 8.42 ± 2.6 years and male female ratio was 1.5:1. Consanguinity of marriage was found in 38.3% cases. Seventy percent of cases were hepatic, 16.7% were neuropsychiatric, 5.0% were hepatic with neuropsychiatric, and 8.3% cases were manifested asymptomatically. Asymptomatic and hepatic WD were reported between 3 and 10 years and most of the neuropsychiatric and hepatic with neuropsychiatric manifested after 10 years of age. More than 50% cases improved, a little more than 20% children died, 18.4% were unchanged and 6.6% were hepatic added neuropsychiatric manifestations. Most of the asymptomatic (100%) and hepatic (61.9%) cases improved. High mortality was found with 76.9% cases of acute liver failure (ALF), 7.7% case of chronic liver disease (CLD) and 25% cases of CLD with portal hypertension (CLD and PH). Most of the neuropsychiatric cases (90.0%), and approximately two-third (66.6%) of hepatic with neuropsychiatric cases remained unchanged. Neuropsychiatric manifestations were added in 15.4% cases of CLD and 25% cases of CLD with PH patient. The treatment was well tolerated in 66% children without any side effects. Low WBC (6.3%) and platelet count (4.3%), vomiting (6.3%), anorexia (4.3%), loss of taste (4.3%), rash (4.3%), and proteinuria (2.1%) were found in few cases. Conclusion: Majority of the children were presented with hepatic manifestations. More than half of patients with WD treated by D-penicillamine (DP) were improved. Significant mortality was found in acute liver failure whereas neuropsychiatric presentations had persistent abnormalities. No major side effects of DP was observed in most of the cases. Early diagnosis and prompt treatment were crucial for better outcome.
Dhaka Shishu (Children) Hospital Journal
Bangladesh Journal of Child Health, 2021
Background: Dengue fever is a major public health problem in Bangladesh. Suspicion, attention, an... more Background: Dengue fever is a major public health problem in Bangladesh. Suspicion, attention, and early tests are necessary to identify concurrent illnesses with dengue. This study was assessed to find out the other infections associated with Dengue fever to minimize morbidity and mortality. Materials & Methods: Hospitalized patients with fever were initially selected. After clinical and laboratory evaluation, fever with dengue NS1 or IgM positive cases were included. Among the 175 dengue patients; during follow-up, some patients had a persistent high fever, cough, dysuria, appearance/deepening of jaundice,and other toxic features that could not correlate with dengue. Relevant investigations were done to find out the co-infections among them. Results: Co-infection was found in 13.1% cases, among 5to 13 years of age group with female predominance. Dengue NS1 was found positive in 39.1% and IgM positive in 60.9% of cases. Typhoid fever 39.1%, paratyphoid fever 4.3%, rickettsial fever...
Acute illness iscaused by bacteria, viruses, and parasites.Co-infection is the simultaneous infec... more Acute illness iscaused by bacteria, viruses, and parasites.Co-infection is the simultaneous infectionof a host by multiple pathogens resulting in a delay in diagnosis and bad prognosis.Currentlycorona virus infection is a pandemic and global health concern. Coronavirus infection in children withconcomitant other infections is rarely reported in our country. This study was performed to find out the corona virus infectionassociated with recent illnesses to minimize morbidity and mortality. Study was done at Dr. M R Khan Shishu Hospital & ICH from April 2020 to June 2020. Patient with fever, rash, vomiting, diarrhea, cough, respiratory distress, dysuria, convulsion, jaundice and other symptoms; admitted in hospital were taken for this study. Diagnosis was made by clinical symptoms plus investigations accordingly and appropriate treatment was given for recent illnesses. During follow up these cases; there was persistence of symptoms and some other new features appeared. These arouse our...
Bangladesh Journal of Child Health, 2018
Background: Adequate neonatal transport is a key component of care of the sick newborns who requi... more Background: Adequate neonatal transport is a key component of care of the sick newborns who require referral to tertiary care center. Poor transportation is one of the iatrogenic factors associated with greater neonatal mortality. Neonatal transport is the greatest challenge faced today in our country. The purpose of this study was to find out characteristics of transport of referred neonates and to idention the factors that contribute to mortality. Methodology: This cross sectional study was conducted in Dhaka Shishu (Children) Hospital from June 2013 to November 2013. Both term and preterm neonates who were referred within first seven days of life were included and those with gross congenital abnormalities and left against medical advice were excluded from the study. After enrollment, data were collected using a structured questionnaire including birth details, interventions before transportation, reasons for referral, and details of transportation. Outcome & duration of hospital ...
Bangladesh Journal of Child Health, Aug 20, 2017
Background: Variceal bleeding is often a life threatening clinical situation in infants and child... more Background: Variceal bleeding is often a life threatening clinical situation in infants and children. Band ligation is the main endoscopic treatment for esophageal varices. Objective: To see the outcome of band ligation of esophageal varices in extra-hepatic and hepatic cases of portal hypertension.
Dhaka Shishu (Children) Hospital Journal
Background: Pediatric colonoscopy is a safe, sensitive and crucial tool for diagnosing as well as... more Background: Pediatric colonoscopy is a safe, sensitive and crucial tool for diagnosing as well as treating children with lower gastrointestinal diseases. In resource-limited countries like Bangladesh, the practice of pediatric colonoscopy remains rudimentary, lacking in trained professionals and appropriate instrumentation. Objectives: The aim of the study was to find out the indications, common colonoscopic findings along with histopathologic evaluation and immediate post procedure complications of colonoscopy in children. Methods: This was a retrospective study; the records of all the patients whose age was less than 18 years and who underwent colonoscopy from January 2017 to December 2021 were studied. Results: Among the total of 196 children (8.23±4.12), the most common indications were lower gastrointestinal bleeding (LGIB) in 107 (54.6%) patients followed by chronic diarrhea in 33 (16.8%), recurrent abdominal pain (RAP) in 16 (8.2%), follow up Inflammatory bowel diseases (IBD)...
Dhaka Shishu (Children) Hospital Journal
Northern International Medical College Journal
Background: Persistent diarrhea is a known cause of mortality, morbidity, and malnutrition in dev... more Background: Persistent diarrhea is a known cause of mortality, morbidity, and malnutrition in developing countries. With recent improvement of rehydration therapy death due to acute diarrhea has been reduced. Though persistent diarrhea accounts for 2-20% of total diarrhea cases, it accounts for 23-62% of all diarrhea related deaths. Objective: The study was done to identify the risk factors associated with persistent diarrhea in children below 5 years of age. Methods: This prospective observational study was conducted in the department of Pediatric Gastroenterology, Hepatology and Nutrition of Dhaka Shishu hospital from July 2019 to June 2020. It included 50 children with persistent diarrhea age between 1 month to <5 years. Detailed history, examination and appropriate investigations were done for all children. Crude odd ratio was calculated for each risk factor by univariate analysis and adjusted odds ratio was calculated by multivariate logistic regression. Results: Most of the...
Dhaka Shishu, Children, Hospital journal, Dec 11, 2022
Background: Upper gastrointestinal endoscopy is an essential, safe and sensitive investigation fo... more Background: Upper gastrointestinal endoscopy is an essential, safe and sensitive investigation for diagnosing pediatric gastrointestinal diseases. In resource-limited countries like Bangladesh, the practice of pediatric endoscopy remains rudimentary, lacking in trained pediatric endoscopists and appropriate-sized endoscopes. There is limited study on paediatric upper GI endoscopy in our country. Objectives: The aim of the study was to find out the indications, common endoscopic findings and immediate post procedure complication of UGI endoscopy in children. Methods: This is a retrospective study; the records of all the patients whose age is less than 18 years and who underwent endoscopy in the last 6 years were studied. Results: Among the total of 384 children (age <18 years), the most common indications were recurrent abdominal pain in 133 (34.7%) patients followed by hematemesis±melena in 99 (25.8%), esophageal varices (follow up with eradication) in 67 (17.5%), recurrent vomiting in 31 (8.1%), foreign body, CLD screening, suspected celiac disease, isolated splenomegaly, corrosive injury, and weight loss. The most common abnormal findings were gastritis in 103 (26.9%) children followed by esophageal varices in 73 (19.2%), duodenitis in 26 (6.8%), foreign body, esophagitis, hiatus hernia, esophageal stricture, esophageal ulcer, gastric ulcer, duodenal ulcer etc. Minor adverse events occurred in 7.0% of children. Conclusion: The commonest indication for Pediatric UGI endoscopy was recurrent abdominal pain and the commonest endoscopic feature was gastritis. No significant post procedure complication was noted in the study.
Egyptian Liver Journal, Nov 18, 2022
Background: Wilson disease (WD) is an inherited disorder of copper metabolism commonly involving ... more Background: Wilson disease (WD) is an inherited disorder of copper metabolism commonly involving the liver, cornea, and brain. Its incidence is increasing day by day worldwide. Early diagnosis and prompt treatment are the key for best outcome. Material and methods: A cross-sectional descriptive study was done from January 2014 to December 2019. Sixty children of both genders between 3 and 18 years were diagnosed by clinical and laboratory profile meeting selected criteria. Results: Mean age was 8.42 ± 2.6 years and male female ratio was 1.5:1. Consanguinity of marriage was found in 38.3% cases. Seventy percent of cases were hepatic, 16.7% were neuropsychiatric, 5.0% were hepatic with neuropsychiatric, and 8.3% cases were manifested asymptomatically. Asymptomatic and hepatic WD were reported between 3 and 10 years and most of the neuropsychiatric and hepatic with neuropsychiatric manifested after 10 years of age. More than 50% cases improved, a little more than 20% children died, 18.4% were unchanged and 6.6% were hepatic added neuropsychiatric manifestations. Most of the asymptomatic (100%) and hepatic (61.9%) cases improved. High mortality was found with 76.9% cases of acute liver failure (ALF), 7.7% case of chronic liver disease (CLD) and 25% cases of CLD with portal hypertension (CLD and PH). Most of the neuropsychiatric cases (90.0%), and approximately two-third (66.6%) of hepatic with neuropsychiatric cases remained unchanged. Neuropsychiatric manifestations were added in 15.4% cases of CLD and 25% cases of CLD with PH patient. The treatment was well tolerated in 66% children without any side effects. Low WBC (6.3%) and platelet count (4.3%), vomiting (6.3%), anorexia (4.3%), loss of taste (4.3%), rash (4.3%), and proteinuria (2.1%) were found in few cases. Conclusion: Majority of the children were presented with hepatic manifestations. More than half of patients with WD treated by D-penicillamine (DP) were improved. Significant mortality was found in acute liver failure whereas neuropsychiatric presentations had persistent abnormalities. No major side effects of DP was observed in most of the cases. Early diagnosis and prompt treatment were crucial for better outcome.
Dhaka Shishu (Children) Hospital Journal
Bangladesh Journal of Child Health, 2021
Background: Dengue fever is a major public health problem in Bangladesh. Suspicion, attention, an... more Background: Dengue fever is a major public health problem in Bangladesh. Suspicion, attention, and early tests are necessary to identify concurrent illnesses with dengue. This study was assessed to find out the other infections associated with Dengue fever to minimize morbidity and mortality. Materials & Methods: Hospitalized patients with fever were initially selected. After clinical and laboratory evaluation, fever with dengue NS1 or IgM positive cases were included. Among the 175 dengue patients; during follow-up, some patients had a persistent high fever, cough, dysuria, appearance/deepening of jaundice,and other toxic features that could not correlate with dengue. Relevant investigations were done to find out the co-infections among them. Results: Co-infection was found in 13.1% cases, among 5to 13 years of age group with female predominance. Dengue NS1 was found positive in 39.1% and IgM positive in 60.9% of cases. Typhoid fever 39.1%, paratyphoid fever 4.3%, rickettsial fever...
Acute illness iscaused by bacteria, viruses, and parasites.Co-infection is the simultaneous infec... more Acute illness iscaused by bacteria, viruses, and parasites.Co-infection is the simultaneous infectionof a host by multiple pathogens resulting in a delay in diagnosis and bad prognosis.Currentlycorona virus infection is a pandemic and global health concern. Coronavirus infection in children withconcomitant other infections is rarely reported in our country. This study was performed to find out the corona virus infectionassociated with recent illnesses to minimize morbidity and mortality. Study was done at Dr. M R Khan Shishu Hospital & ICH from April 2020 to June 2020. Patient with fever, rash, vomiting, diarrhea, cough, respiratory distress, dysuria, convulsion, jaundice and other symptoms; admitted in hospital were taken for this study. Diagnosis was made by clinical symptoms plus investigations accordingly and appropriate treatment was given for recent illnesses. During follow up these cases; there was persistence of symptoms and some other new features appeared. These arouse our...
Bangladesh Journal of Child Health, 2018
Background: Adequate neonatal transport is a key component of care of the sick newborns who requi... more Background: Adequate neonatal transport is a key component of care of the sick newborns who require referral to tertiary care center. Poor transportation is one of the iatrogenic factors associated with greater neonatal mortality. Neonatal transport is the greatest challenge faced today in our country. The purpose of this study was to find out characteristics of transport of referred neonates and to idention the factors that contribute to mortality. Methodology: This cross sectional study was conducted in Dhaka Shishu (Children) Hospital from June 2013 to November 2013. Both term and preterm neonates who were referred within first seven days of life were included and those with gross congenital abnormalities and left against medical advice were excluded from the study. After enrollment, data were collected using a structured questionnaire including birth details, interventions before transportation, reasons for referral, and details of transportation. Outcome & duration of hospital ...
Bangladesh Journal of Child Health, Aug 20, 2017
Background: Variceal bleeding is often a life threatening clinical situation in infants and child... more Background: Variceal bleeding is often a life threatening clinical situation in infants and children. Band ligation is the main endoscopic treatment for esophageal varices. Objective: To see the outcome of band ligation of esophageal varices in extra-hepatic and hepatic cases of portal hypertension.