Federico Magagna - Academia.edu (original) (raw)

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Papers by Federico Magagna

Research paper thumbnail of Adding extra-dimension to tea (Camellia sinensis L.) volatiles profiling and fingerprinting by GC×GC-ToF-MS and soft ionization

Research paper thumbnail of Multidimensionality in Sensomics: Around a Cup of Tea

All rights reserved (including those of translation into other languages). No part of this Abstra... more All rights reserved (including those of translation into other languages). No part of this Abstract Book may be reproduced in any form-by photo-print, microfilm, or any other means-nor transmitted or translated into a machine language without the permission in writing of the publisher. Only single copies of contributions, or parts thereof, may be reproduced for personal use. This Abstract Book was carefully produced in all its parts. Nevertheless, authors, editors and publisher do not warrant the information contained therein to be free of errors. Readers are advised to keep in mind that statements, data, illustrations, procedurals details or other items may inadvertently be inaccurate.

Research paper thumbnail of Challenges in Transfering Methods from Thermal to Differential Flow Modulated Gc×gc-MS/Fid: Food “Omics”Investigations

Research paper thumbnail of Volatiles profiling from high quality cocoa samples at early stages of technological treatment by two-dimensional comprehensive gas chromatography - mass spectrometry

Research paper thumbnail of Tea (Camellia Sinensis L.) Volatiles Profiling by Headspace - Twodimensional Comprehensive Gas Chromatography - Mass Spectrometry: Flavor Compounds Quantification Challenges

Research paper thumbnail of Advanced fingerprinting of high-quality cocoa: Challenges in transferring methods from thermal to differential-flow modulated comprehensive two dimensional gas chromatography

Journal of Chromatography A, 2017

The possibility to transfer methods from thermal to differential-flow modulated comprehensive two... more The possibility to transfer methods from thermal to differential-flow modulated comprehensive two-dimensional gas chromatographic (GC×GC) platforms opens interesting perspectives for routine analysis of complex samples. Flow modulated platforms avoid the use of cryogenics, thereby simplifying laboratory operations and analyst supervision during intensive analytical sessions. This study evaluates the feasibility of transferring a fingerprinting method capable of classifying and discriminating cocoa samples based on the volatiles fraction composition according to their origin and processing steps. Previously developed principles of GC×GC method translation are applied to an original fingerprinting method, developed for a loop-type thermal modulated GC×GC-MS system, to engineer a method for a reverse-injection differential flow modulated platform (GC×2GC-MS/FID) with a dual-parallel secondary column and dual detection. Effective method translation preserves analytes elution order, 1D resolution, and 2D pattern coherence. The experimental results confirm the feasibility of translating fingerprinting method conditions while preserving the informative power of 2D peak patterns for sample classification and discrimination. Correct translation enables effective transfer of metadata (e.g., compound names and MS fragmentation patterns) by automatic template transformation and matching from the original/reference method to its translated counterpart. Although the adoption of a narrow bore (i.e. 0.1mm dc) column in the first-dimension enabled operation under close-to-optimal conditions with the differential-flow modulation platform, due to the dual-parallel columns in the second-dimension, it resulted in lower overall method sensitivity. Nevertheless, fingerprinting accuracy was preserved and most of the key-aroma compounds and technological markers were effectively mapped, thus limiting the loss of fingerprinting information.

Research paper thumbnail of Comprehensive Chemical Fingerprinting of High-Quality Cocoa at Early Stages of Processing: Effectiveness of Combined Untargeted and Targeted Approaches for Classification and Discrimination

Journal of Agricultural and Food Chemistry, 2017

Research paper thumbnail of Combined untargeted and targeted fingerprinting with comprehensive two-dimensional chromatography for volatiles and ripening indicators in olive oil

Analytica Chimica Acta, 2016

Research paper thumbnail of Potential of the reversed-inject differential flow modulator for comprehensive two-dimensional gas chromatography in the quantitative profiling and fingerprinting of essential oils of different complexity

Journal of Chromatography A, 2015

Research paper thumbnail of Parallel dual secondary column-dual detection: A further way of enhancing the informative potential of two-dimensional comprehensive gas chromatography

Journal of Chromatography A, 2014

Research paper thumbnail of Black tea volatiles fingerprinting by comprehensive two-dimensional gas chromatography – Mass spectrometry combined with high concentration capacity sample preparation techniques: Toward a fully automated sensomic assessment

Food Chemistry, 2017

Tea prepared by infusion of dried leaves of Camellia sinensis (L.) Kuntze, is the second world&am... more Tea prepared by infusion of dried leaves of Camellia sinensis (L.) Kuntze, is the second world's most popular beverage, after water. Its consumption is associated with its chemical composition: it influences its sensory and nutritional quality addressing consumer preferences, and potential health benefits. This study aims to obtain an informative chemical signature of the volatile fraction of black tea samples from Ceylon by applying the principles of sensomics. In particular, several high concentration capacity (HCC) sample preparation techniques were tested in combination with GC×GC-MS to investigate chemical signatures of black tea volatiles. This platform, using headspace solid phase microextraction (HS-SPME) with multicomponent fiber as sampling technique, recovers 95% of the key-odorants in a fully automated work-flow. A group 123 components, including key-odorants, technological and botanical tracers, were mapped. The resulting 2D fingerprints were interpreted by pattern recognition tools (i.e. template matching fingerprinting and scripting) providing highly informative chemical signatures for quality assessment.

Research paper thumbnail of Adding extra-dimension to tea (Camellia sinensis L.) volatiles profiling and fingerprinting by GC×GC-ToF-MS and soft ionization

Research paper thumbnail of Multidimensionality in Sensomics: Around a Cup of Tea

All rights reserved (including those of translation into other languages). No part of this Abstra... more All rights reserved (including those of translation into other languages). No part of this Abstract Book may be reproduced in any form-by photo-print, microfilm, or any other means-nor transmitted or translated into a machine language without the permission in writing of the publisher. Only single copies of contributions, or parts thereof, may be reproduced for personal use. This Abstract Book was carefully produced in all its parts. Nevertheless, authors, editors and publisher do not warrant the information contained therein to be free of errors. Readers are advised to keep in mind that statements, data, illustrations, procedurals details or other items may inadvertently be inaccurate.

Research paper thumbnail of Challenges in Transfering Methods from Thermal to Differential Flow Modulated Gc×gc-MS/Fid: Food “Omics”Investigations

Research paper thumbnail of Volatiles profiling from high quality cocoa samples at early stages of technological treatment by two-dimensional comprehensive gas chromatography - mass spectrometry

Research paper thumbnail of Tea (Camellia Sinensis L.) Volatiles Profiling by Headspace - Twodimensional Comprehensive Gas Chromatography - Mass Spectrometry: Flavor Compounds Quantification Challenges

Research paper thumbnail of Advanced fingerprinting of high-quality cocoa: Challenges in transferring methods from thermal to differential-flow modulated comprehensive two dimensional gas chromatography

Journal of Chromatography A, 2017

The possibility to transfer methods from thermal to differential-flow modulated comprehensive two... more The possibility to transfer methods from thermal to differential-flow modulated comprehensive two-dimensional gas chromatographic (GC×GC) platforms opens interesting perspectives for routine analysis of complex samples. Flow modulated platforms avoid the use of cryogenics, thereby simplifying laboratory operations and analyst supervision during intensive analytical sessions. This study evaluates the feasibility of transferring a fingerprinting method capable of classifying and discriminating cocoa samples based on the volatiles fraction composition according to their origin and processing steps. Previously developed principles of GC×GC method translation are applied to an original fingerprinting method, developed for a loop-type thermal modulated GC×GC-MS system, to engineer a method for a reverse-injection differential flow modulated platform (GC×2GC-MS/FID) with a dual-parallel secondary column and dual detection. Effective method translation preserves analytes elution order, 1D resolution, and 2D pattern coherence. The experimental results confirm the feasibility of translating fingerprinting method conditions while preserving the informative power of 2D peak patterns for sample classification and discrimination. Correct translation enables effective transfer of metadata (e.g., compound names and MS fragmentation patterns) by automatic template transformation and matching from the original/reference method to its translated counterpart. Although the adoption of a narrow bore (i.e. 0.1mm dc) column in the first-dimension enabled operation under close-to-optimal conditions with the differential-flow modulation platform, due to the dual-parallel columns in the second-dimension, it resulted in lower overall method sensitivity. Nevertheless, fingerprinting accuracy was preserved and most of the key-aroma compounds and technological markers were effectively mapped, thus limiting the loss of fingerprinting information.

Research paper thumbnail of Comprehensive Chemical Fingerprinting of High-Quality Cocoa at Early Stages of Processing: Effectiveness of Combined Untargeted and Targeted Approaches for Classification and Discrimination

Journal of Agricultural and Food Chemistry, 2017

Research paper thumbnail of Combined untargeted and targeted fingerprinting with comprehensive two-dimensional chromatography for volatiles and ripening indicators in olive oil

Analytica Chimica Acta, 2016

Research paper thumbnail of Potential of the reversed-inject differential flow modulator for comprehensive two-dimensional gas chromatography in the quantitative profiling and fingerprinting of essential oils of different complexity

Journal of Chromatography A, 2015

Research paper thumbnail of Parallel dual secondary column-dual detection: A further way of enhancing the informative potential of two-dimensional comprehensive gas chromatography

Journal of Chromatography A, 2014

Research paper thumbnail of Black tea volatiles fingerprinting by comprehensive two-dimensional gas chromatography – Mass spectrometry combined with high concentration capacity sample preparation techniques: Toward a fully automated sensomic assessment

Food Chemistry, 2017

Tea prepared by infusion of dried leaves of Camellia sinensis (L.) Kuntze, is the second world&am... more Tea prepared by infusion of dried leaves of Camellia sinensis (L.) Kuntze, is the second world's most popular beverage, after water. Its consumption is associated with its chemical composition: it influences its sensory and nutritional quality addressing consumer preferences, and potential health benefits. This study aims to obtain an informative chemical signature of the volatile fraction of black tea samples from Ceylon by applying the principles of sensomics. In particular, several high concentration capacity (HCC) sample preparation techniques were tested in combination with GC×GC-MS to investigate chemical signatures of black tea volatiles. This platform, using headspace solid phase microextraction (HS-SPME) with multicomponent fiber as sampling technique, recovers 95% of the key-odorants in a fully automated work-flow. A group 123 components, including key-odorants, technological and botanical tracers, were mapped. The resulting 2D fingerprints were interpreted by pattern recognition tools (i.e. template matching fingerprinting and scripting) providing highly informative chemical signatures for quality assessment.

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