Magna Manjareeka - Academia.edu (original) (raw)

Papers by Magna Manjareeka

Asian Journal of Pharmaceutical Research and Health Care

National Journal of Physiology, Pharmacy and Pharmacology

Background: Young teachers can skill for better teaching-learning ways can be acquired through st... more Background: Young teachers can skill for better teaching-learning ways can be acquired through structured and cheaper faculty training techniques. Microteaching can be adopted as one such measure to improvise teaching-learning skills among young teachers. Aims and Objectives: This study was conducted also to knew the impact of knowledge and perception regarding microteaching among postgraduate medical students and improvise on them. Also to knew the improvement in teaching skills after training and established the usefulness of this modality of microteaching by looking into its effectiveness. Materials and Methods: The participants were 29 1st year postgraduate students of Kalinga Institute of Medical Sciences, Bhubaneswar, Odisha. One day microteaching workshop was arranged for them in the Medical Education Unit of KIMS. The participants were surveyed through questionnaires (A, B, C, D, and E). McNemar’s Chi-square test did this by comparing between pretesting and post-testing scor...

Journal of Integrative Medicine and Research

Journal of Indian Association for Child and Adolescent Mental Health

Journal of Infection and Public Health, 2013

Background: India has a high tuberculosis (TB) burden. A significant percentage of TB patients ar... more Background: India has a high tuberculosis (TB) burden. A significant percentage of TB patients are human immunodeficiency virus (HIV) positive. As the HIV epidemic is fueling the global TB epidemic, the prevalence of the virus in TB patients is a sensitive indicator of the spread of HIV into the general population in many regions. The aim of this study was to determine the prevalence of HIV-TB co-infection among a less studied population of Eastern India.

Background: Hypertensive disorders of human pregnancy, such as preeclampsia, complicate a sizeabl... more Background: Hypertensive disorders of human pregnancy, such as preeclampsia, complicate a sizeable percentage of all pregnancies, needing its early indication and warning. Aims & Objective: To measure and compare serum uric acid, serum creatinine and serum urea in pre-eclamptic and normotensive groups. Material and Methods: This is a cross-sectional, hospital based study involving 105 age – matched women of South India (devoid of diabetes, urinary tract infections, renal or liver disorders), all in their third trimester singleton pregnancy, at the Obstetrics and Gynaecology Department of Sri Ramachandra Medical College and Hospital, Chennai, India during the period of December 2008 to July 2009. The data were collected following standard procedures and statistical analysis was done using unpaired t – test. Results: The levels of serum uric acid and serum creatinine, expressed in mg / dL were significantly elevated in preeclamptics respectively (5.29 ± 0.84 and 0.72 ± 0.387) when com...

One of the most complicating factors during pregnancy is preeclampsia, a hypertensive disorder le... more One of the most complicating factors during pregnancy is preeclampsia, a hypertensive disorder leading to a variety of problems. Serum electrolyte levels and anion gap, mean weights, SBP/DBP of preeclamptic age-matched women (devoid of diabetes, UTI, renal and liver disorders) in their third trimester, as compared to their normotensive counterparts, have been measured, analysed and compared with results of earlier studies. The preeclamptic group exhibits significant lowering of serum Ca 2+ (-22.6 %) or K + (- 3.85 %) and significant enhancement of each of serum Na + (+ 6.93 %), Cl- (+ 7.25 %), HCO3- (+ 8.74 %) and an insignificant and small increase in anion gap (+ 1.5 %). The observed results do not show any region-specific changes. Most plausible explanations are offered for the observed results. This article can be downloaded from www.ijpbs.net

Asian Journal of Pharmaceutical and Clinical Research

Objective: This study was planned to assess the prevalence of metabolic syndrome (MetS) among doc... more Objective: This study was planned to assess the prevalence of metabolic syndrome (MetS) among doctors of Bhubaneswar. Methods: A cross-sectional, single-centered observational study was conducted among doctors over a period of 8 months after clearance from Institutional Ethical Committee. All consented participants were subjected to anthropometric measurements and physical examination. Fasting plasma glucose and complete lipid profile were estimated using standard procedures after 12 h of overnight fast. MetS was defined according to the Modified National Cholesterol Education Program-Adult Treatment Panel III criteria for MetS screening. Results: Among 170 participants (males - 117 and females - 53), 64 (37.65%) were with MetS. Prevalence of same was higher in males (41.9%) than females (28.3%). The younger doctors (≤40 years) had more prevalence of MetS compared to the elderly (>40 years) doctors (41 [39.8%] vs. 23 [34.3%]). In the males, high blood pressure was the major contr...

Journal of Education and Health Promotion

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

Journal of clinical and diagnostic research : JCDR, 2016

The association between Diabetes Mellitus (DM) and Tuberculosis (TB) poses a strong public health... more The association between Diabetes Mellitus (DM) and Tuberculosis (TB) poses a strong public health challenge. Tribal ethnics possess a different propensity towards infectious and haematological diseases which may influence the inter-relationship of DM and TB and thus merit separate attention. To investigate the prevalence of diabetes in newly diagnosed pulmonary TB patients of tribal ethnicity in Odisha. A cross-sectional study was carried out over a period of 9 months at four designated TB microscopic centres in a tribal district (Malkangiri) of Odisha. A total of 110 tribal adults newly diagnosed with pulmonary TB were examined for Fasting Blood Sugar (FBS) level. Diagnosis of DM and Impaired Fasting Glucose (IFG) were based on cut-off value of FBS recommended by the WHO. Data was entered and analysed using SPSS version 22.0. The prevalence of diabetes and IFG are found to be 13.9% and 8.9%, respectively. A significant difference (p<0.05) was observed between the mean ages of th...

National Journal of Physiology, Pharmacy and Pharmacology, 2016

Background: Changes in QT interval is one of the important electrocardiographic parameters which ... more Background: Changes in QT interval is one of the important electrocardiographic parameters which are reported in many clinical conditions not only in adults but also among the pediatric age group. Diseases with a high risk of sudden deaths in the pediatric age group have initiated the interests among the researchers to focus on electrocardiographic studies. Aims and Objectives: This pilot study was done to obtain the normal QT values for the various age groups and both the genders of pediatric subjects. Materials and Methods: A cross-sectional study was conducted which included 162 healthy children (93 males and 69 females) and electrocardiographic recordings were taken. Subjects with congenital or acquired cardiovascular diseases were excluded from the study. Results: All the participants were divided into three age groups of 1-5 years, 6-10 years, and 11-15 years. It was found that heart rate was inversely proportional to QT/QTc interval while RR interval was directly proportional to both QT and QTc interval. With age, heart rate decreases but other electrocardiograms parameters increase progressively. Although the heart rate is inversely correlated with QT/QTc interval, there is positive correlation of QT/QTc with RR interval. Conclusion: Electrocardiography should be started as a routine investigation in pediatric subjects for the diagnosis of congenital and acquired cardiac diseases and arrhythmias which can be evident from QT interval determination.

National Journal of Physiology, Pharmacy and Pharmacology, 2016

ABSTRACT Aims-Cardiovascular disease (CVD) is a major cause of morbidity and mortality among pati... more ABSTRACT Aims-Cardiovascular disease (CVD) is a major cause of morbidity and mortality among patients with chronic kidney disease (CKD) on maintenance hemodialysis, representing more than 50% of the all-cause mortality. Hemodialysis is associated with both ventricular arrhythmias and dynamic electrocardiographic (ECG) changes. Objectives-The objective of the present study was to see if the serum electrolyte levels and electrocardiographic (ECG) readings are significantly changing after hemodialysis in comparison with pre-hemodialysis levels. Methods- An analytical, cross sectional study was carried out with 301 patients of CKD undergoing hemodialysis. ECG and serum electrolytes (serum sodium, potassium, phosphorus and calcium) levels prior to start of hemodialysis and at end of the same hemodialysis session were documented. Results -They showed ECG changes due to serum electrolyte fluctuations occurring as a result of hemodialysis. Potassium and calcium were the electrolytes which caused ECG changes such as decreased amplitude of P and R waves, ST segment depression and flattening of T waves after hemodialysis. Conclusion- Thus, changing the potassium and calcium concentrate of the dialysate, these ECG changes could be avoided. ECG can be recommended as a diagnostic and prognostic indicator of cardiovascular complications in hemodialysis patients and can be done on a routine basis before and after every hemodialysis sessions.

Journal of Mid-life Health, 2015

Background: Cardiovascular diseases constitute one class of common contributors to morbidity and ... more Background: Cardiovascular diseases constitute one class of common contributors to morbidity and mortality worldwide. Prevalence of overweight and obesity has dramatically increased in developing countries and is related to cardiovascular risk factors. Anthropometric parameters have the advantages in daily clinical practice of being a simple to measure tool with good reproducibility, especially in a developing country like India. Aim of this study is to correlate some anthropometric variables with lipid parameters in healthy subjects and to assess the anthropometric variable which best reflects the altered lipid profile. Materials and Methods: A hospital based cross-sectional study was conducted after the Institutional Ethical Committee Clearance. Included participants (1187) were subjected to anthropometric measurements such as height, weight, waist circumference (WC), and hip circumference using standard procedures on the same morning of the day, as the blood sample was collected after overnight fast and estimated for fasting blood sugar and lipid profile. Results: There is a weak correlation between body mass index (BMI) and lipid parameters. Among all the anthropometric variables studied, WC is best correlated to lipid parameters. The mean values of lipid parameters were not significantly different in BMI <25 and BMI ≥25 groups. Conclusions: WC remains one of the simple and reliable variables which best reflects the lipid profile. In a developing country like India, where measurement of cardiovascular risk factors such as body fat saturation and lipid profile remains difficult in the rural population, WC may be used as an effective tool, without being used as a substitute.

Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme in the hexose monophosphate shunt (HMP shun... more Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme in the hexose monophosphate shunt (HMP shunt) required for the production of reducing equivalents needed to mop up free radicals, thereby keeping hemoglobin in its free state. Deficiency of this enzyme can cause severe neonatal jaundice. This study aims at finding incidence of G6PD in newborns presenting with jaundice in KIMS, Bhubaneswar. Jaundiced newborn babies admitted to NICU were included in this cross-sectional study. Birth weight, gestational age, blood group of mother and baby (to diagnose Rh iso-immunization), bilirubin levels, reticulocyte count, hemoglobin levels, peripheral blood picture for hemolysis, presence of sepsis were noted. Direct Coombs test was also done to determine if the hemolysis was antibody mediated or due to G6PD deficiency. Out of 60 cases considered in this pilot study, 46 cases were males, consistent with the fact that females are mainly carriers and less affected.13 newborns were G6PD deficient,...

Cardiovascular Disease (CVD) is one of the most common contributers of morbidity and mortality wo... more Cardiovascular Disease (CVD) is one of the most common contributers of morbidity and mortality worldwide. Of the many risk factors for development of CVD, age, gender, family history and genetic inheritance are unmodifiable risk factors, while smoking, physical inactivity, poor diet, obesity and dyslipidemia are modifiable. Excess adipose tissue, mostly central obesity, is associated with high CV morbidity and mortality. Abnormal visceral fat produces physiological changes that lead to dyslipidemia, which has direct effects on endothelial dysfunction that in turn increases the risk of cardiovascular events. The present study aims at correlating some anthropometric variables with lipid parameters in healthy subjects and assessing the anthropometric variable that best reflects the altered lipid profile. It is a hospital- based cross sectional study conducted at a private clinic after permission from Institutional Ethical Committee over a period of one year. Of the 2500 consented parti...

Asian Journal of Pharmaceutical Research and Health Care

National Journal of Physiology, Pharmacy and Pharmacology

Background: Young teachers can skill for better teaching-learning ways can be acquired through st... more Background: Young teachers can skill for better teaching-learning ways can be acquired through structured and cheaper faculty training techniques. Microteaching can be adopted as one such measure to improvise teaching-learning skills among young teachers. Aims and Objectives: This study was conducted also to knew the impact of knowledge and perception regarding microteaching among postgraduate medical students and improvise on them. Also to knew the improvement in teaching skills after training and established the usefulness of this modality of microteaching by looking into its effectiveness. Materials and Methods: The participants were 29 1st year postgraduate students of Kalinga Institute of Medical Sciences, Bhubaneswar, Odisha. One day microteaching workshop was arranged for them in the Medical Education Unit of KIMS. The participants were surveyed through questionnaires (A, B, C, D, and E). McNemar’s Chi-square test did this by comparing between pretesting and post-testing scor...

Journal of Integrative Medicine and Research

Journal of Indian Association for Child and Adolescent Mental Health

Journal of Infection and Public Health, 2013

Background: India has a high tuberculosis (TB) burden. A significant percentage of TB patients ar... more Background: India has a high tuberculosis (TB) burden. A significant percentage of TB patients are human immunodeficiency virus (HIV) positive. As the HIV epidemic is fueling the global TB epidemic, the prevalence of the virus in TB patients is a sensitive indicator of the spread of HIV into the general population in many regions. The aim of this study was to determine the prevalence of HIV-TB co-infection among a less studied population of Eastern India.

Background: Hypertensive disorders of human pregnancy, such as preeclampsia, complicate a sizeabl... more Background: Hypertensive disorders of human pregnancy, such as preeclampsia, complicate a sizeable percentage of all pregnancies, needing its early indication and warning. Aims & Objective: To measure and compare serum uric acid, serum creatinine and serum urea in pre-eclamptic and normotensive groups. Material and Methods: This is a cross-sectional, hospital based study involving 105 age – matched women of South India (devoid of diabetes, urinary tract infections, renal or liver disorders), all in their third trimester singleton pregnancy, at the Obstetrics and Gynaecology Department of Sri Ramachandra Medical College and Hospital, Chennai, India during the period of December 2008 to July 2009. The data were collected following standard procedures and statistical analysis was done using unpaired t – test. Results: The levels of serum uric acid and serum creatinine, expressed in mg / dL were significantly elevated in preeclamptics respectively (5.29 ± 0.84 and 0.72 ± 0.387) when com...

One of the most complicating factors during pregnancy is preeclampsia, a hypertensive disorder le... more One of the most complicating factors during pregnancy is preeclampsia, a hypertensive disorder leading to a variety of problems. Serum electrolyte levels and anion gap, mean weights, SBP/DBP of preeclamptic age-matched women (devoid of diabetes, UTI, renal and liver disorders) in their third trimester, as compared to their normotensive counterparts, have been measured, analysed and compared with results of earlier studies. The preeclamptic group exhibits significant lowering of serum Ca 2+ (-22.6 %) or K + (- 3.85 %) and significant enhancement of each of serum Na + (+ 6.93 %), Cl- (+ 7.25 %), HCO3- (+ 8.74 %) and an insignificant and small increase in anion gap (+ 1.5 %). The observed results do not show any region-specific changes. Most plausible explanations are offered for the observed results. This article can be downloaded from www.ijpbs.net

Asian Journal of Pharmaceutical and Clinical Research

Objective: This study was planned to assess the prevalence of metabolic syndrome (MetS) among doc... more Objective: This study was planned to assess the prevalence of metabolic syndrome (MetS) among doctors of Bhubaneswar. Methods: A cross-sectional, single-centered observational study was conducted among doctors over a period of 8 months after clearance from Institutional Ethical Committee. All consented participants were subjected to anthropometric measurements and physical examination. Fasting plasma glucose and complete lipid profile were estimated using standard procedures after 12 h of overnight fast. MetS was defined according to the Modified National Cholesterol Education Program-Adult Treatment Panel III criteria for MetS screening. Results: Among 170 participants (males - 117 and females - 53), 64 (37.65%) were with MetS. Prevalence of same was higher in males (41.9%) than females (28.3%). The younger doctors (≤40 years) had more prevalence of MetS compared to the elderly (>40 years) doctors (41 [39.8%] vs. 23 [34.3%]). In the males, high blood pressure was the major contr...

Journal of Education and Health Promotion

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

Journal of clinical and diagnostic research : JCDR, 2016

The association between Diabetes Mellitus (DM) and Tuberculosis (TB) poses a strong public health... more The association between Diabetes Mellitus (DM) and Tuberculosis (TB) poses a strong public health challenge. Tribal ethnics possess a different propensity towards infectious and haematological diseases which may influence the inter-relationship of DM and TB and thus merit separate attention. To investigate the prevalence of diabetes in newly diagnosed pulmonary TB patients of tribal ethnicity in Odisha. A cross-sectional study was carried out over a period of 9 months at four designated TB microscopic centres in a tribal district (Malkangiri) of Odisha. A total of 110 tribal adults newly diagnosed with pulmonary TB were examined for Fasting Blood Sugar (FBS) level. Diagnosis of DM and Impaired Fasting Glucose (IFG) were based on cut-off value of FBS recommended by the WHO. Data was entered and analysed using SPSS version 22.0. The prevalence of diabetes and IFG are found to be 13.9% and 8.9%, respectively. A significant difference (p<0.05) was observed between the mean ages of th...

National Journal of Physiology, Pharmacy and Pharmacology, 2016

Background: Changes in QT interval is one of the important electrocardiographic parameters which ... more Background: Changes in QT interval is one of the important electrocardiographic parameters which are reported in many clinical conditions not only in adults but also among the pediatric age group. Diseases with a high risk of sudden deaths in the pediatric age group have initiated the interests among the researchers to focus on electrocardiographic studies. Aims and Objectives: This pilot study was done to obtain the normal QT values for the various age groups and both the genders of pediatric subjects. Materials and Methods: A cross-sectional study was conducted which included 162 healthy children (93 males and 69 females) and electrocardiographic recordings were taken. Subjects with congenital or acquired cardiovascular diseases were excluded from the study. Results: All the participants were divided into three age groups of 1-5 years, 6-10 years, and 11-15 years. It was found that heart rate was inversely proportional to QT/QTc interval while RR interval was directly proportional to both QT and QTc interval. With age, heart rate decreases but other electrocardiograms parameters increase progressively. Although the heart rate is inversely correlated with QT/QTc interval, there is positive correlation of QT/QTc with RR interval. Conclusion: Electrocardiography should be started as a routine investigation in pediatric subjects for the diagnosis of congenital and acquired cardiac diseases and arrhythmias which can be evident from QT interval determination.

National Journal of Physiology, Pharmacy and Pharmacology, 2016

ABSTRACT Aims-Cardiovascular disease (CVD) is a major cause of morbidity and mortality among pati... more ABSTRACT Aims-Cardiovascular disease (CVD) is a major cause of morbidity and mortality among patients with chronic kidney disease (CKD) on maintenance hemodialysis, representing more than 50% of the all-cause mortality. Hemodialysis is associated with both ventricular arrhythmias and dynamic electrocardiographic (ECG) changes. Objectives-The objective of the present study was to see if the serum electrolyte levels and electrocardiographic (ECG) readings are significantly changing after hemodialysis in comparison with pre-hemodialysis levels. Methods- An analytical, cross sectional study was carried out with 301 patients of CKD undergoing hemodialysis. ECG and serum electrolytes (serum sodium, potassium, phosphorus and calcium) levels prior to start of hemodialysis and at end of the same hemodialysis session were documented. Results -They showed ECG changes due to serum electrolyte fluctuations occurring as a result of hemodialysis. Potassium and calcium were the electrolytes which caused ECG changes such as decreased amplitude of P and R waves, ST segment depression and flattening of T waves after hemodialysis. Conclusion- Thus, changing the potassium and calcium concentrate of the dialysate, these ECG changes could be avoided. ECG can be recommended as a diagnostic and prognostic indicator of cardiovascular complications in hemodialysis patients and can be done on a routine basis before and after every hemodialysis sessions.

Journal of Mid-life Health, 2015

Background: Cardiovascular diseases constitute one class of common contributors to morbidity and ... more Background: Cardiovascular diseases constitute one class of common contributors to morbidity and mortality worldwide. Prevalence of overweight and obesity has dramatically increased in developing countries and is related to cardiovascular risk factors. Anthropometric parameters have the advantages in daily clinical practice of being a simple to measure tool with good reproducibility, especially in a developing country like India. Aim of this study is to correlate some anthropometric variables with lipid parameters in healthy subjects and to assess the anthropometric variable which best reflects the altered lipid profile. Materials and Methods: A hospital based cross-sectional study was conducted after the Institutional Ethical Committee Clearance. Included participants (1187) were subjected to anthropometric measurements such as height, weight, waist circumference (WC), and hip circumference using standard procedures on the same morning of the day, as the blood sample was collected after overnight fast and estimated for fasting blood sugar and lipid profile. Results: There is a weak correlation between body mass index (BMI) and lipid parameters. Among all the anthropometric variables studied, WC is best correlated to lipid parameters. The mean values of lipid parameters were not significantly different in BMI <25 and BMI ≥25 groups. Conclusions: WC remains one of the simple and reliable variables which best reflects the lipid profile. In a developing country like India, where measurement of cardiovascular risk factors such as body fat saturation and lipid profile remains difficult in the rural population, WC may be used as an effective tool, without being used as a substitute.

Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme in the hexose monophosphate shunt (HMP shun... more Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme in the hexose monophosphate shunt (HMP shunt) required for the production of reducing equivalents needed to mop up free radicals, thereby keeping hemoglobin in its free state. Deficiency of this enzyme can cause severe neonatal jaundice. This study aims at finding incidence of G6PD in newborns presenting with jaundice in KIMS, Bhubaneswar. Jaundiced newborn babies admitted to NICU were included in this cross-sectional study. Birth weight, gestational age, blood group of mother and baby (to diagnose Rh iso-immunization), bilirubin levels, reticulocyte count, hemoglobin levels, peripheral blood picture for hemolysis, presence of sepsis were noted. Direct Coombs test was also done to determine if the hemolysis was antibody mediated or due to G6PD deficiency. Out of 60 cases considered in this pilot study, 46 cases were males, consistent with the fact that females are mainly carriers and less affected.13 newborns were G6PD deficient,...

Cardiovascular Disease (CVD) is one of the most common contributers of morbidity and mortality wo... more Cardiovascular Disease (CVD) is one of the most common contributers of morbidity and mortality worldwide. Of the many risk factors for development of CVD, age, gender, family history and genetic inheritance are unmodifiable risk factors, while smoking, physical inactivity, poor diet, obesity and dyslipidemia are modifiable. Excess adipose tissue, mostly central obesity, is associated with high CV morbidity and mortality. Abnormal visceral fat produces physiological changes that lead to dyslipidemia, which has direct effects on endothelial dysfunction that in turn increases the risk of cardiovascular events. The present study aims at correlating some anthropometric variables with lipid parameters in healthy subjects and assessing the anthropometric variable that best reflects the altered lipid profile. It is a hospital- based cross sectional study conducted at a private clinic after permission from Institutional Ethical Committee over a period of one year. Of the 2500 consented parti...