Maham Ali - Academia.edu (original) (raw)

Maham Ali

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Papers by Maham Ali

Research paper thumbnail of Role of Nanoparticles in Antimicrobial Resistance Modulation

Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an ... more Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an antineoplastic in treating a disease or condition. The pathogens are becoming multidrug resistant due to lavish and non-judicious use of antibiotic. Resistance in one bacterium is transferred to the neighboring bacteria, even while dying bacteria sends signals to other bacteria. The continued wide application or misuse of antibacterial medication has resulted in the emergence of multidrug bacteria which have risen to a remarkable level and are currently a grave matter of concern for medical practitioners dealing with contagious diseases [1]. The resistance to drugs requires the dispensing of raised doses of antibiotics, leading to raised drug toxicity [2]. The development of new antibiotics is long process with the involvement of estimated $1.2 billion USD for new commercial entry. In such situations, market analogues of existing therapeutics within economical and effective range are req...

Research paper thumbnail of Characterizations of novel pesticide-degrading bacterial strains from industrial wastes found in the industrial cities of Pakistan and their biodegradation potential

PeerJ, 2021

Background Lack of infrastructure for disposal of effluents in industries leads to severe polluti... more Background Lack of infrastructure for disposal of effluents in industries leads to severe pollution of natural resources in developing countries. These pollutants accompanied by solid waste are equally hazardous to biological growth. Natural attenuation of these pollutants was evidenced that involved degradation by native microbial communities. The current study encompasses the isolation of pesticide-degrading bacteria from the vicinity of pesticide manufacturing industries. Methods The isolation and identification of biodegrading microbes was done. An enrichment culture technique was used to isolate the selected pesticide-degrading bacteria from industrial waste. Results Around 20 different strains were isolated, among which six isolates showed significant pesticide biodegrading activity. After 16S rRNA analysis, two isolated bacteria were identified as Acinetobacter baumannii (5B) and Acidothiobacillus ferroxidans, and the remaining four were identified as different strains of Pse...

Research paper thumbnail of Role of Nanoparticles in Antimicrobial Resistance Modulation

Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an ... more Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an antineoplastic in treating a disease or condition. The pathogens are becoming multidrug resistant due to lavish and non-judicious use of antibiotic. Resistance in one bacterium is transferred to the neighboring bacteria, even while dying bacteria sends signals to other bacteria. The continued wide application or misuse of antibacterial medication has resulted in the emergence of multidrug bacteria which have risen to a remarkable level and are currently a grave matter of concern for medical practitioners dealing with contagious diseases [1]. The resistance to drugs requires the dispensing of raised doses of antibiotics, leading to raised drug toxicity [2]. The development of new antibiotics is long process with the involvement of estimated $1.2 billion USD for new commercial entry. In such situations, market analogues of existing therapeutics within economical and effective range are req...

Research paper thumbnail of Characterizations of novel pesticide-degrading bacterial strains from industrial wastes found in the industrial cities of Pakistan and their biodegradation potential

PeerJ, 2021

Background Lack of infrastructure for disposal of effluents in industries leads to severe polluti... more Background Lack of infrastructure for disposal of effluents in industries leads to severe pollution of natural resources in developing countries. These pollutants accompanied by solid waste are equally hazardous to biological growth. Natural attenuation of these pollutants was evidenced that involved degradation by native microbial communities. The current study encompasses the isolation of pesticide-degrading bacteria from the vicinity of pesticide manufacturing industries. Methods The isolation and identification of biodegrading microbes was done. An enrichment culture technique was used to isolate the selected pesticide-degrading bacteria from industrial waste. Results Around 20 different strains were isolated, among which six isolates showed significant pesticide biodegrading activity. After 16S rRNA analysis, two isolated bacteria were identified as Acinetobacter baumannii (5B) and Acidothiobacillus ferroxidans, and the remaining four were identified as different strains of Pse...

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