Mahmudul haque - Academia.edu (original) (raw)
Papers by Mahmudul haque
Acta medica Okayama, 1995
Many of Helicobacter species have been found to have novel cholesteryl glucosides (CGs). To study... more Many of Helicobacter species have been found to have novel cholesteryl glucosides (CGs). To study the biosynthetic mechanism of CGs, the lipid profiles of H. pylori and H. mustelae grown in serum-supplemented and cholesterol-restricted serum-free media were investigated. In contrast to the serum-supplemented state, helicobacters had less CGs in the serum-free state; a trace amount of CGs and no CG was detected in H. pylori and H. mustelae, respectively. The proportion of total and individual phospholipid also showed significant alteration. Unknown lipids which did not contain phosphate and sugar were detected in the serum-free state, but not in the serum-supplemented state. The CGs were found to be distributed mainly in the membrane fractions, and one of the unknown lipids was found exclusively in the cytosol fraction. Based on these data, it is apparent that the CGs of helicobacters are synthesized by de novo uptake of cholesterol from the media. The unknown lipids detected in the ...
Journal of Bacteriology, 1995
The lipids of different species of Helicobacter (H.felis, H. muridarum, H. mustelae, H. fennellia... more The lipids of different species of Helicobacter (H.felis, H. muridarum, H. mustelae, H. fennelliae, and H. cinaedi) were studied. Different types of cholesteryl glucosides were found in all of the species studied except H. cinaedi. The total amount of cholesteryl glucosides varied from 14.8% of total lipids in H. mustelae to 33.1% of total lipids in H. felis. The different types of cholesteryl glucosides and their species distribution are cholesteryl-6-O-acyl-alpha-D-glucopyranoside (cholesteryl-6-O-tetradecanoyl-alpha-D-glucopyranoside in H. felis and cholesteryl-6-O-dodecanoyl-alpha-D-glucopyranoside in H. muridarum), cholesteryl-alpha-D-glucopyranoside (H. felis, H. muridarum, H. mustelae, and H. fennelliae), and cholesteryl-6-O-phosphatidyl-alpha-D-glucopyranoside (H. fennelliae). The neutral lipid fractions showed a high percentage of cholesterol, with selective accumulation of free cholesterol. The study thus shows that the characteristic presence of steryl glycosides in Helic...
Journal of Bacteriology, 1995
A chloroform-methanol-extracted lipid of Helicobacter pylori was studied. Three kinds of glycolip... more A chloroform-methanol-extracted lipid of Helicobacter pylori was studied. Three kinds of glycolipids, accounting for about 25% (wt/wt) of the total lipid, were detected and identified to be cholesteryl glucosides. The structures of two of them were determined to be cholesteryl-alpha-D-glucopyranoside and cholesteryl-6-O-tetrade-canoyl-alpha-D-glucopyranoside, and the plausible structure of the third one was identified as cholesteryl-6-O-phosphatidyl-alpha-D-glucopyranoside. Cholesteryl glucosides are very rare in animals and bacteria. Furthermore, those in H. pylori had an alpha-glycosidic linkage, which is rather unusual for natural glycosides, and a phosphate-linked cholesteryl glycoside like the cholesteryl-6-O-phosphatidyl-alpha-D-glucopyranoside has not been reported previously. As the cholesterol glucosides were detected in strains obtained from diverse geographical locations, the presence of cholesteryl glucosides in H. pylori is a very unique and a characteristic feature of ...
Journal of Chittagong Medical College Teachers' Association
Background: Cardiovascular disease is the leading cause of morbidity and mortality in patients of... more Background: Cardiovascular disease is the leading cause of morbidity and mortality in patients of Chronic Kidney Disease (CKD). According to recent studies, insulin resistance and compensatory hyperinsulinemia may have some important roles in cardio-renovascular complications of these patients. So, the aim of this study was to evaluate the insulin resistance status in nondiabetic CKD patients and whether it correlates with glomerular function. Materials and methods: This crosssectional comparative study was carried out in the Department of Biochemistry, Chattogram Medical College from January to December, 2016. A total of 130 subjects of 30- 60 years were included by nonprobability consecutive sampling. Of them, 80 were nondiabetic CKD patients of stages III-V and 50 were healthy controls. Fasting plasma glucose, creatinine and insulin concentrations were measured using automated analyzers. Insulin resistance index was determined by Homeostatic Model Assessment Insulin Resistance (H...
Journal of Chittagong Medical College Teachers' Association
Background: Homocysteine (Hcy) a sulfurcontaining, non-protein a-amino is now considered an indep... more Background: Homocysteine (Hcy) a sulfurcontaining, non-protein a-amino is now considered an independent non-traditional risk factor for vascular disease. In Chronic Kidney Disease (CKD) highly prevalent hyperhomocysteinemia which is often associated with decreased folate concentrations is thought to contribute to increased cardiovascular morbidity. So, the aim of this cross-sectional study was to investigate the relations among serum homocysteine, serum folate and Left Ventricular Ejection Fraction (LVEF) in the context of native CKD patients. Materials and methods: A total of one-thirty (130) participants were recruited between June and July 2016. Among them ninety (90) were CKD patients of stage III, IV & V and forty (40) were healthy controls.eGFR was calculated by MDRD formula. Different groups were created based on serum homocysteine level and eGFR. Results: In this study, hyperhomocysteinemia was seen in 97% CKD patients compared to 52.50% in controls. The CKD patients with el...
Densities and viscosities of the isomers of Butanols ( n-Butanol, iso-Butanol andtert-Butanol ) a... more Densities and viscosities of the isomers of Butanols ( n-Butanol, iso-Butanol andtert-Butanol ) and their binary mixtureswithN,N � �
International Journal of Sustainable Agricultural Technology, 2009
International Journal of Technology Assessment in Health Care, 2020
IntroductionNutrition is critical to the oral health of the individual. From gestation through to... more IntroductionNutrition is critical to the oral health of the individual. From gestation through to end of life, nutrition influences the integrity and function of the dentition and supporting oral structures and has a direct effect on health in general. According to the World Health Organization, diet has an important role in the prevention of oral diseases such as dental caries, dental erosion, defects in oral development, diseases of the oral mucosa, and periodontal disease.MethodsA study was conducted to assess the oral health status and food consumption patterns of students attending the Rotary School and College at Mirpur-14, Dhaka on November 2018. Consent was provided by the school headmaster and guardians. A purposive sample of seventy students was taken. A semi-structured questionnaire and checklist was developed in the English and Bengali languages. Data were presented in simple frequency tables.ResultsAmong the respondents the following eating habits were reported: (i)Thir...
... The day to day activities, the effect of sanskars (rituals) are the key junctures of life sty... more ... The day to day activities, the effect of sanskars (rituals) are the key junctures of life style. The life was much set to a standard which we could be proud of. ... lead profitability in the organization. • Morality and productivity goes on increase by adapting the spirituality @ workplace. ...
Chattagram Maa-O-Shishu Hospital Medical College Journal, 2020
Background: Burn is reported to cause significant alteration of haemocoagulativeparameters, but d... more Background: Burn is reported to cause significant alteration of haemocoagulativeparameters, but due to lack of proper understanding of burn coagulopathy, only theroutine coagulation tests are generally used, even though these provide limiteddiagnostic or prognostic information about burns and postburn complications. So,this study specifically aimed to characterize the changes in plasma FibrinDegradation Product (FDP) together with routine coagulative parameters and theirrelations with burn-severity. Materials and methods: This cross-sectional comparative study was carried out inthe Department of Biochemistry and Department of Burn and Plastic Surgery ofChattogram Medical College Hospital from January to December in 2014. 130subjects of 18 – 65 years enrolled in two groups by nonprobability consecutivesampling. Group-A consisted of 80 patients with minor, moderate and major burnsas per American Burn Association severity classification, whereas Group-B included50 age and sex-matched h...
Journal of Cleaner Production, 2020
Rainwater harvesting (RWH) has become a popular water saving and conservation means across the gl... more Rainwater harvesting (RWH) has become a popular water saving and conservation means across the globe. In many cities, a predetermined rainwater tank size is generally selected without a detail water balance modelling at the location on interest. However, to achieve maximum benefit from a RWH system at a given location, it is desirable to design the system based on the site specific conditions (e.g. local rainfall and loss characteristics) and other relevant design parameters. There have been limited studies on regionalization of RWH system, which can account for the spatial variability in rainfall, loss and water demand characteristics over a given region to provide site-specific design of RWH system. This paper presents a RWH regionalization approach to develop a set of design curves, which assist in the selection of an adequate RWH system at a given location. We use rainfall data from 159 rain gauges across the Greater Sydney region in Australia to develop and test the proposed regionalization approach. It has been found that there is a significant variation in rainfall characteristics across Greater Sydney region and that a common tank size across this region does not present an adequate solution. It has been found that a 5 kL tank can achieve a reliability (i.e. percentage of days the RWH can meet the given demand) of 31 e93% for four people depending on the location in the Greater Sydney region and the types of water use. The developed regional design curves could result in increased water savings across Greater Sydney. The proposed regionalization approach can be adapted to other cities across Australia and the world which present a high rainfall gradient.
American Journal of Gastroenterology, 2008
American Journal of Gastroenterology, 2016
American Journal of Gastroenterology, 2010
Medicine Today, 2017
Fahr's syndrome refers to a rare syndrome characterized by symmetrical and bilateral intracranial... more Fahr's syndrome refers to a rare syndrome characterized by symmetrical and bilateral intracranial calcification. We present a 65-year-old female with Fahr disease, presenting with headache with acute ischaemic stroke with left sided hemiplegia. CT scan of brain reveals irregular variable size hyperdense areas are noted in both basal ganglia regions and in both cerebellar hemisphere.
Journal of Bacteriology, 1996
The lipid and fatty acid profiles of eight Helicobacter spp. (H. nemestrinae, H. acinonyx, H. can... more The lipid and fatty acid profiles of eight Helicobacter spp. (H. nemestrinae, H. acinonyx, H. canis, Helicobacter sp. strain CLO-3, "H. rappini" [Flexispira rappini], H. pametensis, Helicobacter sp. strain Bird-B, and Helicobacter sp. strain Bird-C) and the fatty acid profiles of five additional species (H. pylori, H. felis, H. muridarum, H. mustelae, and H. fennelliae) were analyzed and compared. A heterologous fatty acid profile was observed among the Helicobacter spp., and on that basis the species could be divided into two groups. Group A had 19-carbon cyclopropane fatty acid (19:0cyc) and tetradecanoic acid (14:0) as the major fatty acids, and group B characteristically lacked the 19:0cyc and had hexadecanoic acid (16:0) and octadecenoic (18:1) acids as the major fatty acids. The species of group A are primarily gastric colonizers, and those of group B are primarily intestinal colonizers. Seven of the eight species studied showed the unusual and characteristic presenc...
Medicine Today, 2016
PAM is a rare parenchymal Lung disease. Very few case report are available about PAM in Banglades... more PAM is a rare parenchymal Lung disease. Very few case report are available about PAM in Bangladesh. It is diagnosed incidentally during chest radiograph. It is a autosomal recessive disease and is associated with sporadic or familial mutation of SLC 34A2 gene. Many patients are asymptomatic and have either normal or restrictive pulmonary function. Some patients remain
Water & Environment Dynamics: Proceedings of the 6th International Conference on Water Resources and Environment Research, 3-7 June 2013, Koblenz, Germany, 2013
The Wise Find Pleasure in Water Meandering Through Water Science and Engineering Proceedings of the 35th Iahr World Congress 8 13 September 2013 Chengdu China, 2015
In regression based water demand forecast modelling, identification of suitable predictor variabl... more In regression based water demand forecast modelling, identification of suitable predictor variables is an important step. A variety of factors associated with climate change, population growth, socio-economic conditions and policy issues generally influence urban water demand. These variables are often correlated with each other, which may create problem in building appropriate water demand forecast model. Therefore, selection of the appropriate predictor variables is important for accurate prediction of future water demand which assists in planning and designing efficient water utility system. In this study, principal component analysis (PCA) was carried out using I 0 independent variables in relation to per dwelling water consumption level in the Blue Mountains Water Supply systems in NSW, Australia. Here, principal component scores and multiple linear regression analysis were combined together to develop a principal component regression (PCR) model to predict the future water demand. PCA is a multivariate statistical analysis to reduce a large number of correlated variables into a smaller number of independent components to reduce the dimension of the problem. The results showed that the significant predictor variables in water demand forecasting in the Blue Mountain regions were monthly total rainfall, number of rain days in month, monthly mean maximum temperature, monthly total evaporation, monthly mean daily global solar exposure, water price and water conservation savings. It was also found that the developed PCR model were able to predict future water demand with a high degree of accuracy with an average relative error value of 3.47%. Moreover, it was found that PCR model could be used to eliminate the multicollinearity problem and to reduce the dimension of the variables in the multiple linear regression model
Critical care medicine, 2015
Acta medica Okayama, 1995
Many of Helicobacter species have been found to have novel cholesteryl glucosides (CGs). To study... more Many of Helicobacter species have been found to have novel cholesteryl glucosides (CGs). To study the biosynthetic mechanism of CGs, the lipid profiles of H. pylori and H. mustelae grown in serum-supplemented and cholesterol-restricted serum-free media were investigated. In contrast to the serum-supplemented state, helicobacters had less CGs in the serum-free state; a trace amount of CGs and no CG was detected in H. pylori and H. mustelae, respectively. The proportion of total and individual phospholipid also showed significant alteration. Unknown lipids which did not contain phosphate and sugar were detected in the serum-free state, but not in the serum-supplemented state. The CGs were found to be distributed mainly in the membrane fractions, and one of the unknown lipids was found exclusively in the cytosol fraction. Based on these data, it is apparent that the CGs of helicobacters are synthesized by de novo uptake of cholesterol from the media. The unknown lipids detected in the ...
Journal of Bacteriology, 1995
The lipids of different species of Helicobacter (H.felis, H. muridarum, H. mustelae, H. fennellia... more The lipids of different species of Helicobacter (H.felis, H. muridarum, H. mustelae, H. fennelliae, and H. cinaedi) were studied. Different types of cholesteryl glucosides were found in all of the species studied except H. cinaedi. The total amount of cholesteryl glucosides varied from 14.8% of total lipids in H. mustelae to 33.1% of total lipids in H. felis. The different types of cholesteryl glucosides and their species distribution are cholesteryl-6-O-acyl-alpha-D-glucopyranoside (cholesteryl-6-O-tetradecanoyl-alpha-D-glucopyranoside in H. felis and cholesteryl-6-O-dodecanoyl-alpha-D-glucopyranoside in H. muridarum), cholesteryl-alpha-D-glucopyranoside (H. felis, H. muridarum, H. mustelae, and H. fennelliae), and cholesteryl-6-O-phosphatidyl-alpha-D-glucopyranoside (H. fennelliae). The neutral lipid fractions showed a high percentage of cholesterol, with selective accumulation of free cholesterol. The study thus shows that the characteristic presence of steryl glycosides in Helic...
Journal of Bacteriology, 1995
A chloroform-methanol-extracted lipid of Helicobacter pylori was studied. Three kinds of glycolip... more A chloroform-methanol-extracted lipid of Helicobacter pylori was studied. Three kinds of glycolipids, accounting for about 25% (wt/wt) of the total lipid, were detected and identified to be cholesteryl glucosides. The structures of two of them were determined to be cholesteryl-alpha-D-glucopyranoside and cholesteryl-6-O-tetrade-canoyl-alpha-D-glucopyranoside, and the plausible structure of the third one was identified as cholesteryl-6-O-phosphatidyl-alpha-D-glucopyranoside. Cholesteryl glucosides are very rare in animals and bacteria. Furthermore, those in H. pylori had an alpha-glycosidic linkage, which is rather unusual for natural glycosides, and a phosphate-linked cholesteryl glycoside like the cholesteryl-6-O-phosphatidyl-alpha-D-glucopyranoside has not been reported previously. As the cholesterol glucosides were detected in strains obtained from diverse geographical locations, the presence of cholesteryl glucosides in H. pylori is a very unique and a characteristic feature of ...
Journal of Chittagong Medical College Teachers' Association
Background: Cardiovascular disease is the leading cause of morbidity and mortality in patients of... more Background: Cardiovascular disease is the leading cause of morbidity and mortality in patients of Chronic Kidney Disease (CKD). According to recent studies, insulin resistance and compensatory hyperinsulinemia may have some important roles in cardio-renovascular complications of these patients. So, the aim of this study was to evaluate the insulin resistance status in nondiabetic CKD patients and whether it correlates with glomerular function. Materials and methods: This crosssectional comparative study was carried out in the Department of Biochemistry, Chattogram Medical College from January to December, 2016. A total of 130 subjects of 30- 60 years were included by nonprobability consecutive sampling. Of them, 80 were nondiabetic CKD patients of stages III-V and 50 were healthy controls. Fasting plasma glucose, creatinine and insulin concentrations were measured using automated analyzers. Insulin resistance index was determined by Homeostatic Model Assessment Insulin Resistance (H...
Journal of Chittagong Medical College Teachers' Association
Background: Homocysteine (Hcy) a sulfurcontaining, non-protein a-amino is now considered an indep... more Background: Homocysteine (Hcy) a sulfurcontaining, non-protein a-amino is now considered an independent non-traditional risk factor for vascular disease. In Chronic Kidney Disease (CKD) highly prevalent hyperhomocysteinemia which is often associated with decreased folate concentrations is thought to contribute to increased cardiovascular morbidity. So, the aim of this cross-sectional study was to investigate the relations among serum homocysteine, serum folate and Left Ventricular Ejection Fraction (LVEF) in the context of native CKD patients. Materials and methods: A total of one-thirty (130) participants were recruited between June and July 2016. Among them ninety (90) were CKD patients of stage III, IV & V and forty (40) were healthy controls.eGFR was calculated by MDRD formula. Different groups were created based on serum homocysteine level and eGFR. Results: In this study, hyperhomocysteinemia was seen in 97% CKD patients compared to 52.50% in controls. The CKD patients with el...
Densities and viscosities of the isomers of Butanols ( n-Butanol, iso-Butanol andtert-Butanol ) a... more Densities and viscosities of the isomers of Butanols ( n-Butanol, iso-Butanol andtert-Butanol ) and their binary mixtureswithN,N � �
International Journal of Sustainable Agricultural Technology, 2009
International Journal of Technology Assessment in Health Care, 2020
IntroductionNutrition is critical to the oral health of the individual. From gestation through to... more IntroductionNutrition is critical to the oral health of the individual. From gestation through to end of life, nutrition influences the integrity and function of the dentition and supporting oral structures and has a direct effect on health in general. According to the World Health Organization, diet has an important role in the prevention of oral diseases such as dental caries, dental erosion, defects in oral development, diseases of the oral mucosa, and periodontal disease.MethodsA study was conducted to assess the oral health status and food consumption patterns of students attending the Rotary School and College at Mirpur-14, Dhaka on November 2018. Consent was provided by the school headmaster and guardians. A purposive sample of seventy students was taken. A semi-structured questionnaire and checklist was developed in the English and Bengali languages. Data were presented in simple frequency tables.ResultsAmong the respondents the following eating habits were reported: (i)Thir...
... The day to day activities, the effect of sanskars (rituals) are the key junctures of life sty... more ... The day to day activities, the effect of sanskars (rituals) are the key junctures of life style. The life was much set to a standard which we could be proud of. ... lead profitability in the organization. • Morality and productivity goes on increase by adapting the spirituality @ workplace. ...
Chattagram Maa-O-Shishu Hospital Medical College Journal, 2020
Background: Burn is reported to cause significant alteration of haemocoagulativeparameters, but d... more Background: Burn is reported to cause significant alteration of haemocoagulativeparameters, but due to lack of proper understanding of burn coagulopathy, only theroutine coagulation tests are generally used, even though these provide limiteddiagnostic or prognostic information about burns and postburn complications. So,this study specifically aimed to characterize the changes in plasma FibrinDegradation Product (FDP) together with routine coagulative parameters and theirrelations with burn-severity. Materials and methods: This cross-sectional comparative study was carried out inthe Department of Biochemistry and Department of Burn and Plastic Surgery ofChattogram Medical College Hospital from January to December in 2014. 130subjects of 18 – 65 years enrolled in two groups by nonprobability consecutivesampling. Group-A consisted of 80 patients with minor, moderate and major burnsas per American Burn Association severity classification, whereas Group-B included50 age and sex-matched h...
Journal of Cleaner Production, 2020
Rainwater harvesting (RWH) has become a popular water saving and conservation means across the gl... more Rainwater harvesting (RWH) has become a popular water saving and conservation means across the globe. In many cities, a predetermined rainwater tank size is generally selected without a detail water balance modelling at the location on interest. However, to achieve maximum benefit from a RWH system at a given location, it is desirable to design the system based on the site specific conditions (e.g. local rainfall and loss characteristics) and other relevant design parameters. There have been limited studies on regionalization of RWH system, which can account for the spatial variability in rainfall, loss and water demand characteristics over a given region to provide site-specific design of RWH system. This paper presents a RWH regionalization approach to develop a set of design curves, which assist in the selection of an adequate RWH system at a given location. We use rainfall data from 159 rain gauges across the Greater Sydney region in Australia to develop and test the proposed regionalization approach. It has been found that there is a significant variation in rainfall characteristics across Greater Sydney region and that a common tank size across this region does not present an adequate solution. It has been found that a 5 kL tank can achieve a reliability (i.e. percentage of days the RWH can meet the given demand) of 31 e93% for four people depending on the location in the Greater Sydney region and the types of water use. The developed regional design curves could result in increased water savings across Greater Sydney. The proposed regionalization approach can be adapted to other cities across Australia and the world which present a high rainfall gradient.
American Journal of Gastroenterology, 2008
American Journal of Gastroenterology, 2016
American Journal of Gastroenterology, 2010
Medicine Today, 2017
Fahr's syndrome refers to a rare syndrome characterized by symmetrical and bilateral intracranial... more Fahr's syndrome refers to a rare syndrome characterized by symmetrical and bilateral intracranial calcification. We present a 65-year-old female with Fahr disease, presenting with headache with acute ischaemic stroke with left sided hemiplegia. CT scan of brain reveals irregular variable size hyperdense areas are noted in both basal ganglia regions and in both cerebellar hemisphere.
Journal of Bacteriology, 1996
The lipid and fatty acid profiles of eight Helicobacter spp. (H. nemestrinae, H. acinonyx, H. can... more The lipid and fatty acid profiles of eight Helicobacter spp. (H. nemestrinae, H. acinonyx, H. canis, Helicobacter sp. strain CLO-3, "H. rappini" [Flexispira rappini], H. pametensis, Helicobacter sp. strain Bird-B, and Helicobacter sp. strain Bird-C) and the fatty acid profiles of five additional species (H. pylori, H. felis, H. muridarum, H. mustelae, and H. fennelliae) were analyzed and compared. A heterologous fatty acid profile was observed among the Helicobacter spp., and on that basis the species could be divided into two groups. Group A had 19-carbon cyclopropane fatty acid (19:0cyc) and tetradecanoic acid (14:0) as the major fatty acids, and group B characteristically lacked the 19:0cyc and had hexadecanoic acid (16:0) and octadecenoic (18:1) acids as the major fatty acids. The species of group A are primarily gastric colonizers, and those of group B are primarily intestinal colonizers. Seven of the eight species studied showed the unusual and characteristic presenc...
Medicine Today, 2016
PAM is a rare parenchymal Lung disease. Very few case report are available about PAM in Banglades... more PAM is a rare parenchymal Lung disease. Very few case report are available about PAM in Bangladesh. It is diagnosed incidentally during chest radiograph. It is a autosomal recessive disease and is associated with sporadic or familial mutation of SLC 34A2 gene. Many patients are asymptomatic and have either normal or restrictive pulmonary function. Some patients remain
Water & Environment Dynamics: Proceedings of the 6th International Conference on Water Resources and Environment Research, 3-7 June 2013, Koblenz, Germany, 2013
The Wise Find Pleasure in Water Meandering Through Water Science and Engineering Proceedings of the 35th Iahr World Congress 8 13 September 2013 Chengdu China, 2015
In regression based water demand forecast modelling, identification of suitable predictor variabl... more In regression based water demand forecast modelling, identification of suitable predictor variables is an important step. A variety of factors associated with climate change, population growth, socio-economic conditions and policy issues generally influence urban water demand. These variables are often correlated with each other, which may create problem in building appropriate water demand forecast model. Therefore, selection of the appropriate predictor variables is important for accurate prediction of future water demand which assists in planning and designing efficient water utility system. In this study, principal component analysis (PCA) was carried out using I 0 independent variables in relation to per dwelling water consumption level in the Blue Mountains Water Supply systems in NSW, Australia. Here, principal component scores and multiple linear regression analysis were combined together to develop a principal component regression (PCR) model to predict the future water demand. PCA is a multivariate statistical analysis to reduce a large number of correlated variables into a smaller number of independent components to reduce the dimension of the problem. The results showed that the significant predictor variables in water demand forecasting in the Blue Mountain regions were monthly total rainfall, number of rain days in month, monthly mean maximum temperature, monthly total evaporation, monthly mean daily global solar exposure, water price and water conservation savings. It was also found that the developed PCR model were able to predict future water demand with a high degree of accuracy with an average relative error value of 3.47%. Moreover, it was found that PCR model could be used to eliminate the multicollinearity problem and to reduce the dimension of the variables in the multiple linear regression model
Critical care medicine, 2015