Mansa Gurjar - Academia.edu (original) (raw)
Papers by Mansa Gurjar
Journal of Comparative Neurology
Biochemical and biophysical research communications, Jan 14, 2017
Previous reports show that the desmosomal plaque protein plakophilin3 (PKP3) is essential for des... more Previous reports show that the desmosomal plaque protein plakophilin3 (PKP3) is essential for desmosome formation. Here, we report that PKP3 over-expression decreases calcium dependency for de novo desmosome formation and makes existing cell-cell adhesion junctions more resilient in low calcium medium due to an increase in desmocollin2 expression. PKP3 overexpression increases the stability of other desmosomal proteins independently of the increase in DSC2 levels and regulates desmosome formation and stability by a multimodal mechanism affecting transcription, protein stability and cell border localization of desmosomal proteins.
Journal of Biological Chemistry, 2016
Journal of Cell Science, 2014
Journal of Comparative Neurology
Biochemical and biophysical research communications, Jan 14, 2017
Previous reports show that the desmosomal plaque protein plakophilin3 (PKP3) is essential for des... more Previous reports show that the desmosomal plaque protein plakophilin3 (PKP3) is essential for desmosome formation. Here, we report that PKP3 over-expression decreases calcium dependency for de novo desmosome formation and makes existing cell-cell adhesion junctions more resilient in low calcium medium due to an increase in desmocollin2 expression. PKP3 overexpression increases the stability of other desmosomal proteins independently of the increase in DSC2 levels and regulates desmosome formation and stability by a multimodal mechanism affecting transcription, protein stability and cell border localization of desmosomal proteins.
Journal of Biological Chemistry, 2016
Journal of Cell Science, 2014