Margherita Federici - Academia.edu (original) (raw)

Papers by Margherita Federici

Research paper thumbnail of Imaging of Cranial Nerves: An Overview

Research paper thumbnail of Preliminary study for analysis of modification of disk volume and disk fragment in patients with lumbar contained disk herniation treated with CT-guided ozone-oxygen injection

A kinetic chemotaxis model with attractive interaction by quasistationary chemical signalling is ... more A kinetic chemotaxis model with attractive interaction by quasistationary chemical signalling is considered. The special choice of the turning operator, with velocity jumps biased towards the chemical concentration gradient, permits closed ODE systems for moments of the distribution function of arbitrary order. The system for second order moments exhibits a critical mass phenomeneon. The main result is existence of an aggregated steady state for supercritical mass.

Research paper thumbnail of Imaging Presentation of Bickerstaff Brainstem Encephalitis

The Neurohospitalist, 2021

Bickerstaff Brainstem Encephalitis (BBE) is a rare autoimmune disease, firstly described in 1950s... more Bickerstaff Brainstem Encephalitis (BBE) is a rare autoimmune disease, firstly described in 1950s by Edwin Bickerstaff. It is classically characterized by ophthalmoplegia, ataxia and altered consciousness, with a good prognosis and frequent complete remission. A 38-year-old man presented with slurred speech, ataxia, ophthalmoplegia and fever; he also complained of difficulties in writing and playing the guitar. Figure 1. 38-year-old man with Bickerstaff brainstem encephalitis. MRI at 1.5 T showed a small central lesion of the midbrain, hyperintense on FLAIR (A) and T2-WI (B), and hypointense on T1-WI (C). The lesion was characterized by peripheral restriction of the diffusion (DWI b1⁄41000 s/mm2) (D) and contrast-enhancement on post-gadolinium T1-WI (E).

Research paper thumbnail of Imaging of extraventricular neurocytoma: a systematic literature review

La radiologia medica, 2020

Objective Extraventricular neurocytoma (EVN) was firstly described in 1997. The current literatur... more Objective Extraventricular neurocytoma (EVN) was firstly described in 1997. The current literature regarding imaging of EVN is limited to sporadic case reports and case series. EVN is still poorly considered in the differential diagnosis by neuroradiologists, thus diagnosis remains challenging. In this systematic review, we summarize and discuss computed tomography (CT) and magnetic resonance imaging (MRI) features of EVN cases described in the literature, in order to provide useful informations to neuroradiologists. To the best of our knowledge, this is the most extensive review about imaging of EVN. Materials and methods A systematic review of the literature about imaging of EVN cases was done. Only case reports or case series in which imaging (CT and/or MRI) features were deeply described were included in the revision. Eligibility of studies was assessed independently by two authors and any disagreements resolved by discussion. Results Our search strategy revealed 224 articles. After implementation of inclusion and exclusion criteria, 35 studies were considered, and a total of 79 cases of EVN were analyzed. Conclusion EVN has not specific characteristics, with a large and variable imaging spectrum. Usually it appears as a large tumor, with diameters superior to 40 mm, frequently involving the frontal lobe. CT density and MRI signal intensity typically mirror the presence of cystic, solid, or calcified elements; contrast enhancement is visible in 87% of cases. Today, diagnosis of EVN with only imaging techniques is not univocal; neuroradiologists can only suspect this type of lesion, while the definitive diagnosis remains histological.

Research paper thumbnail of Atypical Extraventricular Neurocytoma (EVN): imaging findings of a disregarded diagnosis

World Neurosurgery, 2019

Extraventricular neurocytoma (EVN) is an exceedingly rare brain tumor. The radiologic and histolo... more Extraventricular neurocytoma (EVN) is an exceedingly rare brain tumor. The radiologic and histologic features of EVN are insidious, and only a few reports and clinical cases describe the characteristics of the tumor, which may show different presentations. We report a case of atypical EVN in a 23-year-old man; Computed Tomography and Magnetic Resonance Imaging features of the mass are described, and differential diagnosis are illustrated. In light of the high variability of imaging presentation, the definitive diagnosis of EVN remains histologic. Although some cases have already been reported in the literature, we believe that the description of our case could be useful to increase the knowledge of this insidious tumor, which has gained recognition only over the past 2 decades and should be included in the differential diagnosis in young patients who present brain tumors.

Research paper thumbnail of Swelling of the submandibular glands after administration of low-osmolarity contrast agent: Ultrasound findings

Journal of ultrasound, 2008

Swelling of the salivary glands occurring after injection of iodine based contrast agent is a rar... more Swelling of the salivary glands occurring after injection of iodine based contrast agent is a rare late adverse reaction. Only a few cases in the literature report such diagnostic findings. We present our color Doppler ultrasound findings in a case of swelling of both submandibular glands occurring after administration of iodinated contrast agent.

Research paper thumbnail of An unusual case of hematuria caused by a foreign body in the bladder: US and radiologic findings

Journal of Ultrasound, 2008

The presence of a foreign body in the bladder or urethra is generally the result of autoerotic ac... more The presence of a foreign body in the bladder or urethra is generally the result of autoerotic acts, psychiatric problems, or therapeutic interventions. It can cause hematuria, pain, and abscess formation, which may lead the patient to seek medical care, but the diagnosis is not always easy. This report describes a man who presented with several months' history of hematuria. Ultrasonography revealed a foreign body in the bladder, and the diagnosis was confirmed by abdominal radiography. The object, which was endoscopically removed, proved to be the ceramic sheath of an endoscopic resector that had been used 2 years earlier for transurethral resection of the prostate.

Research paper thumbnail of Primary pancreatic Burkitt lymphoma presenting as acute pancreatitis

Journal of gastrointestinal cancer, 2014

Research paper thumbnail of Quadro ecografico di un caso di tumefazione delle ghiandole sottomandibolari dopo somministrazione di m.d.c. a bassa osmolarità Swelling of the submandibular glands after administration of low-osmolarity contrast agent: ultrasound findings

Swelling of the salivary glands occurring after injection of iodine based contrast agent is a rar... more Swelling of the salivary glands occurring after injection of iodine based contrast agent is a rare late adverse reaction. Only a few cases in the literature report such diagnostic findings. We present our color Doppler ultrasound findings in a case of swelling of both submandibular glands occurring after administration of iodinated contrast agent.

Research paper thumbnail of Early surfactant treatment in spontaneously breathing Late Preterm Infants (GA 34–36 weeks) with mild to moderate RDS

Early Human Development, 2008

Early Human Development, Volume 84, Issue null, Pages S94, November 2008, Authors:Camilla Gizzi; ... more Early Human Development, Volume 84, Issue null, Pages S94, November 2008, Authors:Camilla Gizzi; Sara Palatta⁎; Ida Giordano; Franco Feleppa; Riccardo Pucello; Chiara Castellano; Margherita Federici; Valentina Panetta; Rocco Agostino. ...

Research paper thumbnail of Imaging of cranial nerves: a pictorial overview

Insights into Imaging, 2019

The human body has 12 pairs of cranial nerves that control motor and sensory functions of the hea... more The human body has 12 pairs of cranial nerves that control motor and sensory functions of the head and neck. The anatomy of cranial nerves is complex and its knowledge is crucial to detect pathological alterations in case of nervous disorders. Therefore, it is necessary to know the most frequent pathologies that may involve cranial nerves and recognize their typical characteristics of imaging. Cranial nerve dysfunctions may be the result of pathological processes of the cranial nerve itself or be related to tumors, inflammation, infectious processes, or traumatic injuries of adjacent structures. Magnetic resonance imaging (MRI) is considered the gold standard in the study of the cranial nerves. Computed tomography (CT) allows, usually, an indirect view of the nerve and is useful to demonstrate the intraosseous segments of cranial nerves, the foramina through which they exit skull base and their pathologic changes. The article is a complete pictorial overview of the imaging of cranial nerves, with anatomic and pathologic descriptions and great attention to illustrative depiction. We believe that it could be a useful guide for radiologists and neuroradiologists to review the anatomy and the most important pathologies that involve cranial nerves and their differential diagnosis.

Research paper thumbnail of Pulmonary ultrasonography in the follow-up of respiratory distress syndrome on preterm newborns. Reduction of X-ray exposure

Journal of ultrasound, 2011

Respiratory distress syndrome (RDS) is the most common cause of respiratory failure in preterm ne... more Respiratory distress syndrome (RDS) is the most common cause of respiratory failure in preterm neonates, whose lungs are often immature. The diagnosis and follow-up are based on clinical and radiographic findings. Due to the problem of air artifacts, ultrasonography (US) is not used routinely in the diagnosis of lung diseases. However, when the alveolar air content decreases, as it does in RDS, characteristic patterns appear that can be observed during US lung examinations. The aim of this study was to determine whether the use of chest radiographs in neonates with RDS could be reduced by the routine use of chest US for follow-up examinations. From April through September 2008, were enrolled all preterm newborns, with very low birth weight (VLBW), consecutive admitted in NICU with clinically and radiologically diagnosed RDS. We performed lung ultrasound examination in this patients. Video-taped US examinations were done every 8-12 h until clinical resolution of the disease was obser...

Research paper thumbnail of Recurrent Epistaxis of Unknown Origin: the Role of Imaging

Acta neurologica Taiwanica, 2019

We report two cases of patients who presented to the Emergency Room (ER) with a history of recurr... more We report two cases of patients who presented to the Emergency Room (ER) with a history of recurrent epistaxis. Conservative treatment was provided to both patients and the most common causes of bleeding were excluded. Patients underwent radiological examinations that revealed the presence of an Intracavernous Carotid Artery Aneurysm (ICAA) extending into the sphenoid sinus through the erosion of postero-lateral bony wall. Aneurysms rupture caused massive nasal bleeding. The purpose of our case report is to illustrate as a very common symptom like epistaxis, in a small number of cases can be underestimated: rare and severe causes of nasal bleeding, as ICAA, should therefore always be considered in the differential diagnosis.

Research paper thumbnail of Lung ultrasound in follow-up of low birth weight with respiratory distress syndrome: clinical application and reduction of x-rays examinations

Poster: "ECR 2011 / C-1724 / Lung ultrasound in follow-up of low birth weight with respirato... more Poster: "ECR 2011 / C-1724 / Lung ultrasound in follow-up of low birth weight with respiratory distress syndrome: clinical application and reduction of x-rays examinations" by: "M. Federici, C. Gizzi, F. Feleppa, R. Agostino, A. Bellelli, V. David, P. V. Federici; Roma/IT"

Research paper thumbnail of Post-traumatic intracranial dislocation of unfractured mandibular condyle

Research paper thumbnail of Imaging of Cranial Nerves: An Overview

Research paper thumbnail of Preliminary study for analysis of modification of disk volume and disk fragment in patients with lumbar contained disk herniation treated with CT-guided ozone-oxygen injection

A kinetic chemotaxis model with attractive interaction by quasistationary chemical signalling is ... more A kinetic chemotaxis model with attractive interaction by quasistationary chemical signalling is considered. The special choice of the turning operator, with velocity jumps biased towards the chemical concentration gradient, permits closed ODE systems for moments of the distribution function of arbitrary order. The system for second order moments exhibits a critical mass phenomeneon. The main result is existence of an aggregated steady state for supercritical mass.

Research paper thumbnail of Imaging Presentation of Bickerstaff Brainstem Encephalitis

The Neurohospitalist, 2021

Bickerstaff Brainstem Encephalitis (BBE) is a rare autoimmune disease, firstly described in 1950s... more Bickerstaff Brainstem Encephalitis (BBE) is a rare autoimmune disease, firstly described in 1950s by Edwin Bickerstaff. It is classically characterized by ophthalmoplegia, ataxia and altered consciousness, with a good prognosis and frequent complete remission. A 38-year-old man presented with slurred speech, ataxia, ophthalmoplegia and fever; he also complained of difficulties in writing and playing the guitar. Figure 1. 38-year-old man with Bickerstaff brainstem encephalitis. MRI at 1.5 T showed a small central lesion of the midbrain, hyperintense on FLAIR (A) and T2-WI (B), and hypointense on T1-WI (C). The lesion was characterized by peripheral restriction of the diffusion (DWI b1⁄41000 s/mm2) (D) and contrast-enhancement on post-gadolinium T1-WI (E).

Research paper thumbnail of Imaging of extraventricular neurocytoma: a systematic literature review

La radiologia medica, 2020

Objective Extraventricular neurocytoma (EVN) was firstly described in 1997. The current literatur... more Objective Extraventricular neurocytoma (EVN) was firstly described in 1997. The current literature regarding imaging of EVN is limited to sporadic case reports and case series. EVN is still poorly considered in the differential diagnosis by neuroradiologists, thus diagnosis remains challenging. In this systematic review, we summarize and discuss computed tomography (CT) and magnetic resonance imaging (MRI) features of EVN cases described in the literature, in order to provide useful informations to neuroradiologists. To the best of our knowledge, this is the most extensive review about imaging of EVN. Materials and methods A systematic review of the literature about imaging of EVN cases was done. Only case reports or case series in which imaging (CT and/or MRI) features were deeply described were included in the revision. Eligibility of studies was assessed independently by two authors and any disagreements resolved by discussion. Results Our search strategy revealed 224 articles. After implementation of inclusion and exclusion criteria, 35 studies were considered, and a total of 79 cases of EVN were analyzed. Conclusion EVN has not specific characteristics, with a large and variable imaging spectrum. Usually it appears as a large tumor, with diameters superior to 40 mm, frequently involving the frontal lobe. CT density and MRI signal intensity typically mirror the presence of cystic, solid, or calcified elements; contrast enhancement is visible in 87% of cases. Today, diagnosis of EVN with only imaging techniques is not univocal; neuroradiologists can only suspect this type of lesion, while the definitive diagnosis remains histological.

Research paper thumbnail of Atypical Extraventricular Neurocytoma (EVN): imaging findings of a disregarded diagnosis

World Neurosurgery, 2019

Extraventricular neurocytoma (EVN) is an exceedingly rare brain tumor. The radiologic and histolo... more Extraventricular neurocytoma (EVN) is an exceedingly rare brain tumor. The radiologic and histologic features of EVN are insidious, and only a few reports and clinical cases describe the characteristics of the tumor, which may show different presentations. We report a case of atypical EVN in a 23-year-old man; Computed Tomography and Magnetic Resonance Imaging features of the mass are described, and differential diagnosis are illustrated. In light of the high variability of imaging presentation, the definitive diagnosis of EVN remains histologic. Although some cases have already been reported in the literature, we believe that the description of our case could be useful to increase the knowledge of this insidious tumor, which has gained recognition only over the past 2 decades and should be included in the differential diagnosis in young patients who present brain tumors.

Research paper thumbnail of Swelling of the submandibular glands after administration of low-osmolarity contrast agent: Ultrasound findings

Journal of ultrasound, 2008

Swelling of the salivary glands occurring after injection of iodine based contrast agent is a rar... more Swelling of the salivary glands occurring after injection of iodine based contrast agent is a rare late adverse reaction. Only a few cases in the literature report such diagnostic findings. We present our color Doppler ultrasound findings in a case of swelling of both submandibular glands occurring after administration of iodinated contrast agent.

Research paper thumbnail of An unusual case of hematuria caused by a foreign body in the bladder: US and radiologic findings

Journal of Ultrasound, 2008

The presence of a foreign body in the bladder or urethra is generally the result of autoerotic ac... more The presence of a foreign body in the bladder or urethra is generally the result of autoerotic acts, psychiatric problems, or therapeutic interventions. It can cause hematuria, pain, and abscess formation, which may lead the patient to seek medical care, but the diagnosis is not always easy. This report describes a man who presented with several months' history of hematuria. Ultrasonography revealed a foreign body in the bladder, and the diagnosis was confirmed by abdominal radiography. The object, which was endoscopically removed, proved to be the ceramic sheath of an endoscopic resector that had been used 2 years earlier for transurethral resection of the prostate.

Research paper thumbnail of Primary pancreatic Burkitt lymphoma presenting as acute pancreatitis

Journal of gastrointestinal cancer, 2014

Research paper thumbnail of Quadro ecografico di un caso di tumefazione delle ghiandole sottomandibolari dopo somministrazione di m.d.c. a bassa osmolarità Swelling of the submandibular glands after administration of low-osmolarity contrast agent: ultrasound findings

Swelling of the salivary glands occurring after injection of iodine based contrast agent is a rar... more Swelling of the salivary glands occurring after injection of iodine based contrast agent is a rare late adverse reaction. Only a few cases in the literature report such diagnostic findings. We present our color Doppler ultrasound findings in a case of swelling of both submandibular glands occurring after administration of iodinated contrast agent.

Research paper thumbnail of Early surfactant treatment in spontaneously breathing Late Preterm Infants (GA 34–36 weeks) with mild to moderate RDS

Early Human Development, 2008

Early Human Development, Volume 84, Issue null, Pages S94, November 2008, Authors:Camilla Gizzi; ... more Early Human Development, Volume 84, Issue null, Pages S94, November 2008, Authors:Camilla Gizzi; Sara Palatta⁎; Ida Giordano; Franco Feleppa; Riccardo Pucello; Chiara Castellano; Margherita Federici; Valentina Panetta; Rocco Agostino. ...

Research paper thumbnail of Imaging of cranial nerves: a pictorial overview

Insights into Imaging, 2019

The human body has 12 pairs of cranial nerves that control motor and sensory functions of the hea... more The human body has 12 pairs of cranial nerves that control motor and sensory functions of the head and neck. The anatomy of cranial nerves is complex and its knowledge is crucial to detect pathological alterations in case of nervous disorders. Therefore, it is necessary to know the most frequent pathologies that may involve cranial nerves and recognize their typical characteristics of imaging. Cranial nerve dysfunctions may be the result of pathological processes of the cranial nerve itself or be related to tumors, inflammation, infectious processes, or traumatic injuries of adjacent structures. Magnetic resonance imaging (MRI) is considered the gold standard in the study of the cranial nerves. Computed tomography (CT) allows, usually, an indirect view of the nerve and is useful to demonstrate the intraosseous segments of cranial nerves, the foramina through which they exit skull base and their pathologic changes. The article is a complete pictorial overview of the imaging of cranial nerves, with anatomic and pathologic descriptions and great attention to illustrative depiction. We believe that it could be a useful guide for radiologists and neuroradiologists to review the anatomy and the most important pathologies that involve cranial nerves and their differential diagnosis.

Research paper thumbnail of Pulmonary ultrasonography in the follow-up of respiratory distress syndrome on preterm newborns. Reduction of X-ray exposure

Journal of ultrasound, 2011

Respiratory distress syndrome (RDS) is the most common cause of respiratory failure in preterm ne... more Respiratory distress syndrome (RDS) is the most common cause of respiratory failure in preterm neonates, whose lungs are often immature. The diagnosis and follow-up are based on clinical and radiographic findings. Due to the problem of air artifacts, ultrasonography (US) is not used routinely in the diagnosis of lung diseases. However, when the alveolar air content decreases, as it does in RDS, characteristic patterns appear that can be observed during US lung examinations. The aim of this study was to determine whether the use of chest radiographs in neonates with RDS could be reduced by the routine use of chest US for follow-up examinations. From April through September 2008, were enrolled all preterm newborns, with very low birth weight (VLBW), consecutive admitted in NICU with clinically and radiologically diagnosed RDS. We performed lung ultrasound examination in this patients. Video-taped US examinations were done every 8-12 h until clinical resolution of the disease was obser...

Research paper thumbnail of Recurrent Epistaxis of Unknown Origin: the Role of Imaging

Acta neurologica Taiwanica, 2019

We report two cases of patients who presented to the Emergency Room (ER) with a history of recurr... more We report two cases of patients who presented to the Emergency Room (ER) with a history of recurrent epistaxis. Conservative treatment was provided to both patients and the most common causes of bleeding were excluded. Patients underwent radiological examinations that revealed the presence of an Intracavernous Carotid Artery Aneurysm (ICAA) extending into the sphenoid sinus through the erosion of postero-lateral bony wall. Aneurysms rupture caused massive nasal bleeding. The purpose of our case report is to illustrate as a very common symptom like epistaxis, in a small number of cases can be underestimated: rare and severe causes of nasal bleeding, as ICAA, should therefore always be considered in the differential diagnosis.

Research paper thumbnail of Lung ultrasound in follow-up of low birth weight with respiratory distress syndrome: clinical application and reduction of x-rays examinations

Poster: "ECR 2011 / C-1724 / Lung ultrasound in follow-up of low birth weight with respirato... more Poster: "ECR 2011 / C-1724 / Lung ultrasound in follow-up of low birth weight with respiratory distress syndrome: clinical application and reduction of x-rays examinations" by: "M. Federici, C. Gizzi, F. Feleppa, R. Agostino, A. Bellelli, V. David, P. V. Federici; Roma/IT"

Research paper thumbnail of Post-traumatic intracranial dislocation of unfractured mandibular condyle