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Papers by Maria-Louise Sidoroff
New York Heritage Digital Collections, 2023
A photographic documentary of Labor Day scenes in 1975 at Gosman’s Restaurant in Montauk, N.Y.
EXARC Journal, 2019
The objective of this series of experimental pottery firings with camel dung fuel was to isolate ... more The objective of this series of experimental pottery firings with camel dung fuel was to isolate the function of this fuel type within the context of a simple mode of pottery firing for data applicable to studies of ancient pottery manufacture.
Bulletin of Primitive Technology, 2000
Bulletin of Primitive Technology, 2009
Sensory and autonomic neuropathy affects the majority of type II diabetic patients. Clinically, a... more Sensory and autonomic neuropathy affects the majority of type II diabetic patients. Clinically, autonomic evaluation often focuses on sudomotor function yet this is rarely assessed in animal models. We undertook morphological and functional studies to assess large myelinated and small unmyelinated axons in the db/db type II diabetes mouse model. We observed that autonomic innervation of sweat glands in the footpads was significantly reduced in db/db mice compared to control db/+ mice and this deficit was greater compared to reductions in intraepidermal sensory innervation of adjacent epidermis. Additionally, db/db mice formed significantly fewer sweat droplets compared to controls as early as 6 weeks of age, a time when no statistical differences were observed electrophysiologically between db/db and db/+ mice studies of large myelinated sensory and motor nerves. The rate of sweat droplet formation was significantly slower and the sweat droplet size larger and more variable in db/db mice compared to controls. Whereas pilocarpine and glycopyrrolate increased and decreased sweating, respectively, in 6 month-old controls, db/db mice did not respond to pharmacologic manipulations. Our findings indicate autonomic neuropathy is an early and prominent deficit in the db/db model and have implications for the development of therapies for peripheral diabetic neuropathy. Autonomic dysfunction is common in diabetes and affects many important functions including exercise tolerance, gut peristalsis, sexual function and cardiovascular health; yet it is often underappreciated. Cardiac autonomic dysfunction contributes to increased rates of sudden death in diabetes and prediabetes 1 , while reduced pedal sweating is integral to diabetic ulcer formation and poor wound healing 2 . The annual cost of diabetic neuropathy in the US was estimated at $10.9 billion (2001 dollars) 3 . In men, erectile dysfunction, in part caused by autonomic neuropathy, is often a presenting symptom of diabetes and heralds occult vascular disease. Methods to assess autonomic function are technically complex and results can be confounded by medications for common disorders (hypertension) 4 , diet (coffee) and circadian patterns 5 . Cardiac autonomic assessment includes measurement of heart rate variability (HRV), blood pressure testing, and Valsalva maneuvers that require dynamic patient participation and cooperation 6,7 . These variables can complicate routine clinical autonomic assessment. Animal models are an attractive tool to study autonomic function as they allow the opportunity to control many of the factors that complicate human autonomic measurements, yet, there have been relatively few such studies and most have focused on heart rate control. In contrast to human diabetic cardiac autonomic neuropathy in which patients typically exhibit tachycardia 8 , most experimental studies have demonstrated bradycardia . In type 1 (streptozotocin-induced) diabetic rodents, abnormalities in autonomic axons have been reported, including dystrophic noradregenergic axons in mesenteric nerve . Dependent on the model, genetic background, and the time of assay, mouse models of diabetic sensory neuropathy are known to develop both hyper-and hypo-sensitivity to thermal stimuli, loss of sensory fibers in the footpads, and reduced nerve conduction . Type I diabetes is most often modeled by streptozotocin-mediated β -cell ablation in rodents, resulting in reduced epidermal innervation and sensory neuropathy . Rodent models of type II diabetes include, among others, the widely used models leptin-deficient ob/ob mice and leptin receptor-deficient db/db mice . The db/db mice exhibit features of neuropathy, such as decreased nerve conduction velocity 27 , axonal atrophy 28 , and reduced epidermal innervation 20 . Studies on these models have
Bulletin of Primitive Technology, 1993
Bulletin of Primitive Technology, 1996
Bulletin of Primitive Technology, 1997
Ethnoarchaeology, 2015
This study of the Zizia Pottery Factory in Jizza, central Jordan, offers empirical data and socio... more This study of the Zizia Pottery Factory in Jizza, central Jordan, offers empirical data and sociocultural observations of a modern industrialized system comprised of interrelated aspects: artisans, scale and technology of production, spatial and social organization, and distribution. Since the factory processes, with a few exceptions, are not far removed from those known from antiquity, the modern quantitative data and on-site observations in this report may be used to interpret archaeological evidence or to reconstruct the framework of an industrialized pottery workshop from a limited archaeological record.
An interdisciplinary investigation of the technology of a select group of Cupisnique, Salinar, an... more An interdisciplinary investigation of the technology of a select group of Cupisnique, Salinar, and provincial Inka ceramics from Farf?n, in the Jequetepeque Valley, Peru, identifies the elements of a North Coast technological style in ceramic manufacture. Through multiple lines of ...
EXARC Journal, 2012
Mark Butler organized the First Annual REARC Conference, which was held on October 16-17, 2010 at... more Mark Butler organized the First Annual REARC Conference, which was held on October 16-17, 2010 at the Schiele Museum in Gastonia, North Carolina. The conference was a great success. Dr. Ann Tippet, Schiele Museum Director, and Steve Watts, Director of Southeast Native American Studies (SENAS), welcomed an international group of forty-five attendees.
Bulletin of Primitive Technology, 1994
New York Heritage Digital Collections, 2023
A photographic documentary of Labor Day scenes in 1975 at Gosman’s Restaurant in Montauk, N.Y.
EXARC Journal, 2019
The objective of this series of experimental pottery firings with camel dung fuel was to isolate ... more The objective of this series of experimental pottery firings with camel dung fuel was to isolate the function of this fuel type within the context of a simple mode of pottery firing for data applicable to studies of ancient pottery manufacture.
Bulletin of Primitive Technology, 2000
Bulletin of Primitive Technology, 2009
Sensory and autonomic neuropathy affects the majority of type II diabetic patients. Clinically, a... more Sensory and autonomic neuropathy affects the majority of type II diabetic patients. Clinically, autonomic evaluation often focuses on sudomotor function yet this is rarely assessed in animal models. We undertook morphological and functional studies to assess large myelinated and small unmyelinated axons in the db/db type II diabetes mouse model. We observed that autonomic innervation of sweat glands in the footpads was significantly reduced in db/db mice compared to control db/+ mice and this deficit was greater compared to reductions in intraepidermal sensory innervation of adjacent epidermis. Additionally, db/db mice formed significantly fewer sweat droplets compared to controls as early as 6 weeks of age, a time when no statistical differences were observed electrophysiologically between db/db and db/+ mice studies of large myelinated sensory and motor nerves. The rate of sweat droplet formation was significantly slower and the sweat droplet size larger and more variable in db/db mice compared to controls. Whereas pilocarpine and glycopyrrolate increased and decreased sweating, respectively, in 6 month-old controls, db/db mice did not respond to pharmacologic manipulations. Our findings indicate autonomic neuropathy is an early and prominent deficit in the db/db model and have implications for the development of therapies for peripheral diabetic neuropathy. Autonomic dysfunction is common in diabetes and affects many important functions including exercise tolerance, gut peristalsis, sexual function and cardiovascular health; yet it is often underappreciated. Cardiac autonomic dysfunction contributes to increased rates of sudden death in diabetes and prediabetes 1 , while reduced pedal sweating is integral to diabetic ulcer formation and poor wound healing 2 . The annual cost of diabetic neuropathy in the US was estimated at $10.9 billion (2001 dollars) 3 . In men, erectile dysfunction, in part caused by autonomic neuropathy, is often a presenting symptom of diabetes and heralds occult vascular disease. Methods to assess autonomic function are technically complex and results can be confounded by medications for common disorders (hypertension) 4 , diet (coffee) and circadian patterns 5 . Cardiac autonomic assessment includes measurement of heart rate variability (HRV), blood pressure testing, and Valsalva maneuvers that require dynamic patient participation and cooperation 6,7 . These variables can complicate routine clinical autonomic assessment. Animal models are an attractive tool to study autonomic function as they allow the opportunity to control many of the factors that complicate human autonomic measurements, yet, there have been relatively few such studies and most have focused on heart rate control. In contrast to human diabetic cardiac autonomic neuropathy in which patients typically exhibit tachycardia 8 , most experimental studies have demonstrated bradycardia . In type 1 (streptozotocin-induced) diabetic rodents, abnormalities in autonomic axons have been reported, including dystrophic noradregenergic axons in mesenteric nerve . Dependent on the model, genetic background, and the time of assay, mouse models of diabetic sensory neuropathy are known to develop both hyper-and hypo-sensitivity to thermal stimuli, loss of sensory fibers in the footpads, and reduced nerve conduction . Type I diabetes is most often modeled by streptozotocin-mediated β -cell ablation in rodents, resulting in reduced epidermal innervation and sensory neuropathy . Rodent models of type II diabetes include, among others, the widely used models leptin-deficient ob/ob mice and leptin receptor-deficient db/db mice . The db/db mice exhibit features of neuropathy, such as decreased nerve conduction velocity 27 , axonal atrophy 28 , and reduced epidermal innervation 20 . Studies on these models have
Bulletin of Primitive Technology, 1993
Bulletin of Primitive Technology, 1996
Bulletin of Primitive Technology, 1997
Ethnoarchaeology, 2015
This study of the Zizia Pottery Factory in Jizza, central Jordan, offers empirical data and socio... more This study of the Zizia Pottery Factory in Jizza, central Jordan, offers empirical data and sociocultural observations of a modern industrialized system comprised of interrelated aspects: artisans, scale and technology of production, spatial and social organization, and distribution. Since the factory processes, with a few exceptions, are not far removed from those known from antiquity, the modern quantitative data and on-site observations in this report may be used to interpret archaeological evidence or to reconstruct the framework of an industrialized pottery workshop from a limited archaeological record.
An interdisciplinary investigation of the technology of a select group of Cupisnique, Salinar, an... more An interdisciplinary investigation of the technology of a select group of Cupisnique, Salinar, and provincial Inka ceramics from Farf?n, in the Jequetepeque Valley, Peru, identifies the elements of a North Coast technological style in ceramic manufacture. Through multiple lines of ...
EXARC Journal, 2012
Mark Butler organized the First Annual REARC Conference, which was held on October 16-17, 2010 at... more Mark Butler organized the First Annual REARC Conference, which was held on October 16-17, 2010 at the Schiele Museum in Gastonia, North Carolina. The conference was a great success. Dr. Ann Tippet, Schiele Museum Director, and Steve Watts, Director of Southeast Native American Studies (SENAS), welcomed an international group of forty-five attendees.
Bulletin of Primitive Technology, 1994