Maria Lozano - Academia.edu (original) (raw)

Papers by Maria Lozano

Research paper thumbnail of Clonality analysis of B-lymphoid proliferations using the polymerase chain reaction

Cancer, 1996

BACKGROUND. Polymerase chain reaction (PCR) based assays are becoming more reliable, simpler, and... more BACKGROUND. Polymerase chain reaction (PCR) based assays are becoming more reliable, simpler, and faster alternatives to traditional Southern blot hybridization (SBH) analysis for the detection of clonal immunoglobulin heavy chain (IgH) gene rearrangements. However, a variety of technical approaches have been reported with markedly different results.

Research paper thumbnail of The arithmeticity of the figure eight knot orbifolds

Research paper thumbnail of On universal groups and three-manifolds

Inventiones Mathematicae, 1987

In his notes [Th2] Thurston described a hyperbolic three-orbifold B 3 whose singular locus is the... more In his notes [Th2] Thurston described a hyperbolic three-orbifold B 3 whose singular locus is the Borromean rings and whose isotropy groups are all cyclic of order four. Thus, this orbifold is defined by a finitely generated group U of orientation-preserving isometries of hyperbolic three-space IH 3.

Research paper thumbnail of Solving the Mapping Problem in User Interface Design by Seamless Integration in IdealXML

The mapping problem has been defined as the way to map models involved throughout the development... more The mapping problem has been defined as the way to map models involved throughout the development life cycle of user interfaces. Model-based design of user interfaces has followed a long tradition of establishing models and maintaining mappings between them. This paper introduces a formal definition of potential mappings between models with its corresponding syntax so as to create a uniform and integrated framework for adding, removing, and modifying mappings throughout the development life cycle. For the first time, the mappings can be established from any source model to any target model, one or many, in the same formalism. Those models include task, domain, presentation, dialog, and context of use, which is itself decomposed into user, platform, and environment. IdealXML consists of a Java application allowing the designer to edit any model at any time, and any element of any model, but also to establish a set of mappings, either manually or automatically based on a mapping model.

Research paper thumbnail of Towards Adaptive User Interface Generation: One Step Closer to People

User interface generation has become a Software Engineering branch of increasing interest, probab... more User interface generation has become a Software Engineering branch of increasing interest, probably due to the great amount of money, time and effort used to develop user interfaces and the increasing level of exigency of user requirements for usability and accessibility (W3C, 2002) compliances. There are different kinds of users, and that is a fact we cannot ignore. Human society is full of diversity and that must be reflected in human-computer interaction design. Thus, we need to engage users in a new kind of interaction concept where user interfaces are tailored-made, and where user interfaces are intelligent and adaptive. A new generation of specification techniques is necessary to face these challenges successfully. Model-based design has proved to be a powerful tool to achieve these goals. A first step towards adaptive user interface generation is introduced by means of the concept of connector applied to model-based design of user interfaces.

Research paper thumbnail of Bridging the Gap: Developing 2D and 3D User Interfaces with the IDEAS Methodology

Most user interface development methodologies have been conceived based on experience from the de... more Most user interface development methodologies have been conceived based on experience from the development of traditional PC-based systems. However, computer and display technologies are changing. Sizes range from large surrounding displays to small mobile devices. Besides, 3D graphics is no longer limited to graphics workstations, as most PCs are shipped with specialized hardware, and 3D standards are being developed for mobile devices. User interface engineering should not be left out of this progress. With that concern in mind, the IDEAS methodology is presented, a novel environment which allows the development of both 2D and 3D user interfaces. A case of study is used to show the details of the proposed development process.

Research paper thumbnail of Lecturas con actividades

Research paper thumbnail of Clonality analysis of B-lymphoid proliferations using the polymerase chain reaction

Cancer, 1996

BACKGROUND. Polymerase chain reaction (PCR) based assays are becoming more reliable, simpler, and... more BACKGROUND. Polymerase chain reaction (PCR) based assays are becoming more reliable, simpler, and faster alternatives to traditional Southern blot hybridization (SBH) analysis for the detection of clonal immunoglobulin heavy chain (IgH) gene rearrangements. However, a variety of technical approaches have been reported with markedly different results.

Research paper thumbnail of The arithmeticity of the figure eight knot orbifolds

Research paper thumbnail of On universal groups and three-manifolds

Inventiones Mathematicae, 1987

In his notes [Th2] Thurston described a hyperbolic three-orbifold B 3 whose singular locus is the... more In his notes [Th2] Thurston described a hyperbolic three-orbifold B 3 whose singular locus is the Borromean rings and whose isotropy groups are all cyclic of order four. Thus, this orbifold is defined by a finitely generated group U of orientation-preserving isometries of hyperbolic three-space IH 3.

Research paper thumbnail of Solving the Mapping Problem in User Interface Design by Seamless Integration in IdealXML

The mapping problem has been defined as the way to map models involved throughout the development... more The mapping problem has been defined as the way to map models involved throughout the development life cycle of user interfaces. Model-based design of user interfaces has followed a long tradition of establishing models and maintaining mappings between them. This paper introduces a formal definition of potential mappings between models with its corresponding syntax so as to create a uniform and integrated framework for adding, removing, and modifying mappings throughout the development life cycle. For the first time, the mappings can be established from any source model to any target model, one or many, in the same formalism. Those models include task, domain, presentation, dialog, and context of use, which is itself decomposed into user, platform, and environment. IdealXML consists of a Java application allowing the designer to edit any model at any time, and any element of any model, but also to establish a set of mappings, either manually or automatically based on a mapping model.

Research paper thumbnail of Towards Adaptive User Interface Generation: One Step Closer to People

User interface generation has become a Software Engineering branch of increasing interest, probab... more User interface generation has become a Software Engineering branch of increasing interest, probably due to the great amount of money, time and effort used to develop user interfaces and the increasing level of exigency of user requirements for usability and accessibility (W3C, 2002) compliances. There are different kinds of users, and that is a fact we cannot ignore. Human society is full of diversity and that must be reflected in human-computer interaction design. Thus, we need to engage users in a new kind of interaction concept where user interfaces are tailored-made, and where user interfaces are intelligent and adaptive. A new generation of specification techniques is necessary to face these challenges successfully. Model-based design has proved to be a powerful tool to achieve these goals. A first step towards adaptive user interface generation is introduced by means of the concept of connector applied to model-based design of user interfaces.

Research paper thumbnail of Bridging the Gap: Developing 2D and 3D User Interfaces with the IDEAS Methodology

Most user interface development methodologies have been conceived based on experience from the de... more Most user interface development methodologies have been conceived based on experience from the development of traditional PC-based systems. However, computer and display technologies are changing. Sizes range from large surrounding displays to small mobile devices. Besides, 3D graphics is no longer limited to graphics workstations, as most PCs are shipped with specialized hardware, and 3D standards are being developed for mobile devices. User interface engineering should not be left out of this progress. With that concern in mind, the IDEAS methodology is presented, a novel environment which allows the development of both 2D and 3D user interfaces. A case of study is used to show the details of the proposed development process.

Research paper thumbnail of Lecturas con actividades