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Papers by Marie Wren

Research paper thumbnail of Treatment and preservation at the extremes of reproductive age: a case report outlining the ethical dilemmas

Journal of assisted reproduction and genetics, 2015

The purpose of the study was to report a livebirth from a cryopreserved embryo created from autol... more The purpose of the study was to report a livebirth from a cryopreserved embryo created from autologous oocytes collected at 47 years and 9 months that outlines the ethical difficulties of decision-making at the extreme of reproductive age. The method used was IVF and embryo cryopreservation within an assisted conception unit prior to adjuvant cancer treatment in a nulliparous patient diagnosed with breast carcinoma (47 years and 9 months at oocyte collection). A 47-year-old nulliparous woman was diagnosed with breast malignancy during work-up for fertility treatment. Ovarian stimulation yielded one embryo from four oocytes that was cryopreserved to allow completion of adjuvant treatment. Subsequent embryo transfer cycle led to a live birth of a healthy baby girl at term, weighing 3.37 kg. This paper demonstrates the oldest reported age of autologous oocyte collection to have achieved a livebirth. In women where most would consider treatment futile, we highlight the difficulties in d...

Research paper thumbnail of Swedish in-vitro fertilisation study

The Lancet, 2000

1. Lancet. 2000 Mar 4;355(9206):846-7. Swedish in-vitro fertilisation study. D'Souza SW, Ric... more 1. Lancet. 2000 Mar 4;355(9206):846-7. Swedish in-vitro fertilisation study. D'Souza SW, Richards B, Lieberman BA. Comment on: Lancet. 1999 Nov 6;354(9190):1579-85. PMID: 10711954 [PubMed - indexed for MEDLINE]. ...

Research paper thumbnail of The influence of body mass index on in vitro fertilization treatment outcome, risk of miscarriage, and pregnancy outcome

Fertility and Sterility, 2003

depending on the number of oocytes retrieved. The enhanced cryopreservation with increasing oocyt... more depending on the number of oocytes retrieved. The enhanced cryopreservation with increasing oocyte number may improve efficiency of the donor cycle.

Research paper thumbnail of Obstetric outcome in 232 ovum donation pregnancies

BJOG: An International Journal of Obstetrics and Gynaecology, 1998

Objective To study the obstetric outcome of ovum donation pregnancies.

Research paper thumbnail of Is that any value in treating women with elevated basal follicular stimulating hormone?

Fertility and Sterility, 2003

depending on the number of oocytes retrieved. The enhanced cryopreservation with increasing oocyt... more depending on the number of oocytes retrieved. The enhanced cryopreservation with increasing oocyte number may improve efficiency of the donor cycle.

Research paper thumbnail of Treatment and preservation at the extremes of reproductive age: a case report outlining the ethical dilemmas

Journal of assisted reproduction and genetics, 2015

The purpose of the study was to report a livebirth from a cryopreserved embryo created from autol... more The purpose of the study was to report a livebirth from a cryopreserved embryo created from autologous oocytes collected at 47 years and 9 months that outlines the ethical difficulties of decision-making at the extreme of reproductive age. The method used was IVF and embryo cryopreservation within an assisted conception unit prior to adjuvant cancer treatment in a nulliparous patient diagnosed with breast carcinoma (47 years and 9 months at oocyte collection). A 47-year-old nulliparous woman was diagnosed with breast malignancy during work-up for fertility treatment. Ovarian stimulation yielded one embryo from four oocytes that was cryopreserved to allow completion of adjuvant treatment. Subsequent embryo transfer cycle led to a live birth of a healthy baby girl at term, weighing 3.37 kg. This paper demonstrates the oldest reported age of autologous oocyte collection to have achieved a livebirth. In women where most would consider treatment futile, we highlight the difficulties in d...

Research paper thumbnail of Swedish in-vitro fertilisation study

The Lancet, 2000

1. Lancet. 2000 Mar 4;355(9206):846-7. Swedish in-vitro fertilisation study. D'Souza SW, Ric... more 1. Lancet. 2000 Mar 4;355(9206):846-7. Swedish in-vitro fertilisation study. D'Souza SW, Richards B, Lieberman BA. Comment on: Lancet. 1999 Nov 6;354(9190):1579-85. PMID: 10711954 [PubMed - indexed for MEDLINE]. ...

Research paper thumbnail of The influence of body mass index on in vitro fertilization treatment outcome, risk of miscarriage, and pregnancy outcome

Fertility and Sterility, 2003

depending on the number of oocytes retrieved. The enhanced cryopreservation with increasing oocyt... more depending on the number of oocytes retrieved. The enhanced cryopreservation with increasing oocyte number may improve efficiency of the donor cycle.

Research paper thumbnail of Obstetric outcome in 232 ovum donation pregnancies

BJOG: An International Journal of Obstetrics and Gynaecology, 1998

Objective To study the obstetric outcome of ovum donation pregnancies.

Research paper thumbnail of Is that any value in treating women with elevated basal follicular stimulating hormone?

Fertility and Sterility, 2003

depending on the number of oocytes retrieved. The enhanced cryopreservation with increasing oocyt... more depending on the number of oocytes retrieved. The enhanced cryopreservation with increasing oocyte number may improve efficiency of the donor cycle.

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