Mario Gorgojo - Academia.edu (original) (raw)

Papers by Mario Gorgojo

Sensors, Apr 13, 2023

This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY

Effect of Binge Drinking on TMT A and B stratified by gender.</p

Correlation between TMT A and TMT B with age at onset of alcohol consumption.</p

Mathematics

Parkinson’s disease (PD) is often detected only in later stages, when about 50% of nigrostriatal ... more Parkinson’s disease (PD) is often detected only in later stages, when about 50% of nigrostriatal dopaminergic projections have already been lost. Thus, there is a need for biomarkers to monitor the earliest phases, especially for those that are at higher risk. In this work, we explore the use of machine learning methods to diagnose PD by analyzing gait alterations via an inertial sensors system that participants in the study wear while walking down a 15 m long corridor in three different scenarios. To achieve this goal, we have trained six well-known machine learning models: support vector machines, logistic regression, neural networks, k nearest neighbors, decision trees and random forest. We thoroughly explored several ways to mitigate the problems derived from the small amount of available data. We found that, while achieving accuracy rates of over 70% is quite common, the accuracy of the best model trained is only slightly above the 80% mark. This model has high precision and sp...

Sociodemographic characteristics.</p

Journal of Clinical Medicine

To analyze how balance and other physical capacities evolved after surgery in patients with a bim... more To analyze how balance and other physical capacities evolved after surgery in patients with a bimalleolar fracture and how these capacities and clinical variables (immobilization or unloading time) contribute to restoring patients’ functionality, 22 patients and 10 healthy people (HC) were assessed for static and dynamic balance (Y-Balance test, YBT), dorsiflexion ankle mobility (ADFROM) and hip strength at 6 and 12 months after surgery. Patients’ functional status was assessed through the Olerud Molander Ankle Score (OMAS) and the American Orthopaedic Foot and Ankle Society (AOFAS) score. Twenty-one patients with ankle fractures who completed the study showed a worse static and dynamic balance at 6 months. The YBT in the anterior direction (YBTA) revealed balance deficits in the operated limb at 12 months compared to the non-operated limb (−5.6%) and the HC (−6.7%). They also showed a decreased ADFROM compared to the non-operated limb (−7.4°) and the HC (−11°). In addition, medium-...

Parkinsonism & Related Disorders

$Research paper thumbnail of Clinical assessment, gait analysis and reliability of measurement with the G walk inertial sensor in subjects with ankle fracture 6 months after surgery$

Background: Ankle fractures can cause significant functional impairment in the short and long ter... more Background: Ankle fractures can cause significant functional impairment in the short and long term. In recent years, gait analysis using inertial sensors has gained special relevance as a reliable measurement system.Objectives: In patients with bimalleolar ankle fracture, to identify the differences between the operated and healthy ankle in the spatial-temporal gait parameters and plantar pressures; likewise, to study their relationship with clinical parameters and functional scales. Finally, to assess the reliability of a single inertial sensor, placed on the lumbar spine, in our study population.Design: Cross-sectional study.Methods: Twenty-two subjects with bimalleolar ankle fractures were included in the study. An analysis of the spatial-temporal gait parameters and plantar pressures was carried out using an inertial system (G-WALK) and a pressure platform (P-WALK). Sociodemographic and clinical information was previously collected. Differences between the operated and healthy a...

Sensors

Ankle fractures can cause significant functional impairment in the short and long term. In recent... more Ankle fractures can cause significant functional impairment in the short and long term. In recent years, gait analysis using inertial sensors has gained special relevance as a reliable measurement system. This study aimed to evaluate the differences in spatiotemporal gait parameters and clinical–functional measurements in patients with bimalleolar ankle fracture and healthy subjects, to study the correlation between the different variables, and to analyze the test–retest reliability of a single inertial sensor in our study population. Twenty-two subjects with bimalleolar ankle fracture six months after surgery and eleven healthy subjects were included in the study. Spatiotemporal parameters were analyzed with the G-WALK sensor. Functional scales and clinical measures were collected beforehand. In the ankle fracture group, the main differences were obtained in bilateral parameters (effect size: 0.61 ≤ d ≤ 0.80). Between-group differences were found in cadence, speed, stride length, a...

$Research paper thumbnail of Quantifying balance deficit in people with ankle fracture six months after surgical intervention through the Y-Balance test$

Frontiers in Human Neuroscience

Introduction: In recent years, the study of the benefits that physical exercise has on brain heal... more Introduction: In recent years, the study of the benefits that physical exercise has on brain health has acquired special relevance. In order to implement exercise as an intervention to protect the brain, it is important to have a more clear idea of its effect in the young population. However, few studies have been carried out on these ages. Objective: The main objective of our study was to evaluate the association between physical activity (PA) with memory and executive function, in university students, analyzing the modulatory effect of sex. Methodology: We collected socio-demographic and life habit information, as well as data on the PA that was carried out during the previous week using the international PA questionnaire short version (IPAQ-SF) questionnaire in 206 university students (mean age 19.55 ± 2.39; 67.5% women). Memory and executive function were assessed using a comprehensive battery of validate cognitive tests. Univariate and multivariate analyses were performed to correlate PA with cognitive tests scores and to evaluate the potential synergistic role of sex. Results: The main finding was that the total amount of PA correlated positively with several tests that evaluated aspects of executive function, specifically Stroop Colors (Pearson's r = 0.17; p = 0.01) and the Stroop Test Color-Word (Pearson's r = 0.15. p = 0.03). These results were adjusted by a large number of possible confounders and modifying variables in a multivariate analysis, like age, sex, academic record, day of the week, and time at which the test was performed. Additionally, we found out that sex had a synergistic effect with PA on the executive test Trail making test-A (TMTA), and in women, this association was stronger than in men. The more PA women reported, the better they performed, that is to say that they took less time to finalize the TMT-A (interaction term between PA and sex: b = −0.0009; p = 0.014). Conclusion: Our study adds evidence of the benefit of PA in cognition in the young population, specifically in the executive inhibitory control, and more significantly in women.

PLOS ONE, 2016

Our aim was to evaluate whether or not alcohol consumption in the form of binge drinking is assoc... more Our aim was to evaluate whether or not alcohol consumption in the form of binge drinking is associated with alterations of memory and executive functions in a population of university students. At the same time, we have studied the role of potential modulating factors, such as the APOE genotype or physical exercise.University students enrolled in academic year 2013-2014 at Escuelas Universitarias Gimbernat-Cantabria, affiliated with the University of Cantabria, were invited to participate in the study. We gathered sociodemographic data and details regarding the lifestyle of 206 students (mean age 19.55 ± 2.39; 67.5% women). We evaluated memory and executive functions via a series of validated cognitive tests. Participants were classified as binge drinkers (BD) and non-BD. Using Student's t-distribution we studied the association between cognitive tests and BD patterns. Multivariate analyses were carried out via multiple linear regression. 47.6% of the students were found to be BD. The BD differed significantly from the non-BD in their results in the executive functions test TMT B (43.41 ± 13.30 vs 37.40 ± 9.77; p = 0.0003). Adjusting by age, sex, academic records, age at which they started consuming alcohol, cannabis consumption, level of physical activity and other possible modifying variables, the association was statistically significant (p = 0.009). We noticed a statistically significant inverse correlation (Pearson's r 2 =-0.192; p = 0.007) between TMT B and starting age of alcohol consumption. Differences were observed in another executive functions test, TMT A, but only in the group of women (19.73±6.1 BD vs 17.78±5.4 non-BD p = 0.05). In spite of the young age of our participants, BD was associated with a lower performance in the executive functions test (TMT B). These deficits were related to the age at which they started drinking alcohol, suggesting an accumulative effect.

Revista Internacional de Medicina y Ciencias de la Actividad Fisica y del Deporte

ABSTRACT Pubalgia is a kind of clinical manifestation of the injury of musculoskeletal structures... more ABSTRACT Pubalgia is a kind of clinical manifestation of the injury of musculoskeletal structures, diseases of the peripheral nervous system, genitourinary and digestive system, and rheumatic diseases. The most common injuries for the onset of inguinal pain in athletes are the injury of common aponeurosis of the rectus abdominis and adductor longus muscles (in relation with processes of inguinal hernia (15%) and pubic osteoarthropathy), and hip injuries (especially femoroacetabular impingement and tears of acetabular labrum (22%)). In fact, a great number of patients with groin and pubic pain suffer two or more injuries together. In conclusion, a correct differential diagnosis is necessary to choose the best treatment.

Alzheimer. Realidades e investigación en demencia, 2014