Marizélia Ribeiro - Academia.edu (original) (raw)
Papers by Marizélia Ribeiro
Vulnerable Children and Youth Studies, 2018
Journal of Women's Health, 2021
Background: Few studies have investigated the association between violence against pregnant women... more Background: Few studies have investigated the association between violence against pregnant women in terms of recurrence, complications, and perpetrators of violence, and breastfeeding duration. This study verifies whether recurrent violence, violence with pregnancy complications, and intimate partner violence (IPV) against pregnant women are associated with shorter exclusive breastfeeding up to the infant's 6th month and breastfeeding up to the 12th month of life. Materials and Methods: A cohort study with a convenience sample of 1,146 pregnant women was performed. Follow-up assessments were conducted at birth, and at 12-36 months. Survival analysis was used to verify whether recurrent violence, violence with pregnancy complications, and IPV were associated with reduced duration of exclusive breastfeeding and breastfeeding. Results: The adjusted Cox regression revealed no difference regarding exclusive breastfeeding duration among mothers exposed or not exposed to violence and according to who perpetrated the violence. The risk of an infant not being breastfed within the first 12 months of life increased in cases of violence before/during pregnancy (95% confidence interval [CI] = 1.03-1.88), recurrent psychological/physical/sexual violence during pregnancy (95% CI = 1.11-1.92), recurrent psychological violence (95% CI = 1.05-1.96), and recurrent physical/sexual violence (95% CI = 1.01-2.39). Violence with pregnancy complications (95% CI = 0.94-2.22) was not associated with breastfeeding interruption. Similar risks of breastfeeding interruption were observed for IPV (95% CI = 0.96-1.87) and violence perpetrated by other family members (95% CI = 0.83-1.89). Conclusions: We observed a shorter breastfeeding duration up to 12 months of life in cases of recurrent violence.
O trabalho apresenta o desenvolvimento de um metodo para a identificacao de sementes haploides qu... more O trabalho apresenta o desenvolvimento de um metodo para a identificacao de sementes haploides que possuam o gene marcador R1navajo em milho utilizando a espectroscopia no infravermelho proximo e a analise discriminante por minimos quadrados parciais (PLS-DA). Os espectros de absorbância foram obtidos a partir de 137 sementes de quatro genotipos de milho, na regiao do infravermelho proximo utilizando um equipamento MicroNIR, modelo 1700. A combinacao de Standard Normal Variate - SNV, primeira derivada por Savitzky-Golay e dados centrados na media foi a sequencia de pre-processamento mais eficiente para minimizar os efeitos de espalhamento e deslocamentos da linha de base. O modelo PLS-DA alcancou 100% de classificacoes corretas, considerando os dados de validacao externa para os quatro genotipos de milho avaliados. A analise de parâmetros como sensibilidade, especificidade e eficiencia no conjunto de testes de validacao do modelo resultou em valores iguais a 100% para o conjunto de ...
O objetivo deste trabalho foi avaliar o efeito do avanco de geracoes na obtencao de haploides de ... more O objetivo deste trabalho foi avaliar o efeito do avanco de geracoes na obtencao de haploides de milho em populacoes-fonte de diferentes grupos heteroticos. Os genotipos avaliados foram originados de um campo de inducao de haploidia implantado na Embrapa Milho e Sorgo, em Sete Lagoas, Minas Gerais, em setembro de 2015. Para as avaliacoes, foram utilizadas 10 populacoes-fonte, sendo quatro do grupo heterotico Flint e seis do grupo Dent, nas geracoes F1 e F2. Para inducao, utilizou-se o indutor materno obtido do cruzamento entre plantas do hibrido TAIL P1 x TAIL P2. Para cada populacao-fonte, foram tomadas sete espigas polinizadas manualmente para avaliacao. Foram determinados o numero medio de graos por espiga, o numero de sementes haploides, as taxas de inducao de haploidia e a expressao do gene R1-navajo, dentre outros caracteres. Para comparacao dos dados obtidos entre geracoes e grupos heteroticos, utilizouse o teste de Wilcoxon. Identificou-se um maior numero de haploides em gen...
An analysis was conducted to evaluate if the severity of caries is associated with protein-calori... more An analysis was conducted to evaluate if the severity of caries is associated with protein-calorie malnutrition in preschool children. The cross-sectional study was performed on a retrospective cohort of 625 children aged 24-71 months attending daycare centers in São Luís, Maranhão. A hierarchical model was evaluated at five levels: 1.) Socio-economic variables (economic group, mother's educational level and skin color); 2) Access variables; 3) Low birth weight (LBW) and exclusive breastfeeding; 4) Weight per height at 12 months; and 5) Severity of caries and albumin (Alb) levels. The outcome was protein-calorie malnourishment (weight per height z score < -2). The prevalence of outcome was 5.0% and the prevalence of caries was 32%. At the first level, the variables were not associated with the outcome, but the economic group was maintained until the final model. The variables in the second and third levels were not significant. At the fourth level, weight for height at 12 mon...
International Journal of Infectious Diseases, 2021
Pedigree analysis has long been an essential tool in human genetics as well as a staple of geneti... more Pedigree analysis has long been an essential tool in human genetics as well as a staple of genetics education. Students of genetics might be surprised to learn that human pedigrees were first popularized in the United States by proponents of eugenics, the pseudoscientific social movement aimed at improving the genetic quality of the human race. Notably, the influential eugenicist Charles B. Davenport employed pedigree charts to support his belief that not only were such medical conditions as Huntington disease and albinism inherited in a simple Mendelian fashion, but so too were such characteristics as alcoholism, criminality, and "feeblemindedness." We now see the flaws in Davenport' s pedigree analysis, but at the time, it was the latest scientific advance. The misuse of pedigree analysis during the eugenics era may serve as a cautionary tale for those who are now harnessing the latest genetic technologies to solve complex problems.
Revista Brasileira de Saúde Materno Infantil, 2020
Objectives: to analyze differences in prevalence and perpetrators of violence against women befor... more Objectives: to analyze differences in prevalence and perpetrators of violence against women before and during pregnancy. Methods: this is a cross-sectional study with a sample of 1,446 pregnant women interviewed in 2010 and 2011 in the São Luís municipality (Brazil). Thirteen questions measured psychological, physical and sexual violence in the 12 months before and during pregnancy. Psychological/physical/sexual violence was defined as any type of violence perpetrated against the interviewees. The perpetrators were categorized into intimate partner, other family members, community members, and multiple perpetrators. Differences between violence before and during pregnancy were analyzed by the chi-square test. Results: psychological/physical/sexual and psychological violence were more prevalent during pregnancy than before gestation (p<0.001). Insults, humiliation and intimidation (p<0.05) were more frequently reported during pregnancy. An intimate partner was the most frequent...
Revista Brasileira de Saúde Materno Infantil, 2020
Objectives: to analyze differences in prevalence and perpetrators of violence against women befor... more Objectives: to analyze differences in prevalence and perpetrators of violence against women before and during pregnancy. Methods: this is a cross-sectional study with a sample of 1,446 pregnant women interviewed in 2010 and 2011 in the São Luís municipality (Brazil). Thirteen questions measured psychological, physical and sexual violence in the 12 months before and during pregnancy. Psychological/physical/sexual violence was defined as any type of violence perpetrated against the interviewees. The perpetrators were categorized into intimate partner, other family members, community members, and multiple perpetrators. Differences between violence before and during pregnancy were analyzed by the chi-square test. Results: psychological/physical/sexual and psychological violence were more prevalent during pregnancy than before gestation (p<0.001). Insults, humiliation and intimidation (p<0.05) were more frequently reported during pregnancy. An intimate partner was the most frequent...
Revista Brasileira de Saúde Materno Infantil, 2020
Objectives: to analyze differences in prevalence and perpetrators of violence against women befor... more Objectives: to analyze differences in prevalence and perpetrators of violence against women before and during pregnancy. Methods: this is a cross-sectional study with a sample of 1,446 pregnant women interviewed in 2010 and 2011 in the São Luís municipality (Brazil). Thirteen questions measured psychological, physical and sexual violence in the 12 months before and during pregnancy. Psychological/physical/sexual violence was defined as any type of violence perpetrated against the interviewees. The perpetrators were categorized into intimate partner, other family members, community members, and multiple perpetrators. Differences between violence before and during pregnancy were analyzed by the chi-square test. Results: psychological/physical/sexual and psychological violence were more prevalent during pregnancy than before gestation (p<0.001). Insults, humiliation and intimidation (p<0.05) were more frequently reported during pregnancy. An intimate partner was the most frequent...
Revista do Instituto de Medicina Tropical de São Paulo, 2020
This is an open-access article distributed under the terms of the Creative Commons Attribution Li... more This is an open-access article distributed under the terms of the Creative Commons Attribution License.
Viruses, 2020
The short duration of viremia, low blood viral load, inaccessibility to timely specific diagnosti... more The short duration of viremia, low blood viral load, inaccessibility to timely specific diagnostic tests, and cross-reactions with other flaviviruses have hindered laboratory confirmation of Congenital Zika Syndrome (CZS). This study analyzes the positivity of the plaque reduction neutralization test (PRNT) in children with clinical or imaging characteristics of CZS and its association with laboratory, clinical, and imaging characteristics. The 94 clinical cases of CZS submitted to the ZIKV PRNT90 test were followed from 2016 to 2018. The mean age of children at PRNT90 collection was 22 ± 6 months Standard Deviation. The ZIKV PRNT90 was positive (titer ≥ 10) in 40 (42.5%) children. ZIKV PRNT90 positivity was associated with severe microcephaly in newborns (p = 0.016), lower head circumference z-score at birth (p = 0.043) and 24 months of age (p = 0.031), and severe reduction of the cerebral parenchyma volume (p = 0.021), expressing greater disease severity. Negative PRNT90 in childr...
Cadernos de Saúde Pública, 2020
Resumo: Embora se reconheça que depressão e ansiedade resultem em incapacidades, bem como em prej... more Resumo: Embora se reconheça que depressão e ansiedade resultem em incapacidades, bem como em prejuízos laborais e para os sistemas de saúde, pesquisas de base populacional são escassas no Brasil. Este estudo avaliou a prevalência de transtornos mentais em adolescentes, jovens e adultos e sua relação com características sociodemográficas em cinco coortes de nascimento (RPS): Ribeirão Preto (São Paulo), Pelotas (Rio Grande do Sul) e São Luís (Maranhão), Brasil. Episódio depressivo, risco de suicídio, fobia social e transtorno de ansiedade generalizada foram avaliados usando-se o Mini International Neuropsychiatric Interview. Intervalos de confiança bootstrap foram estimados e prevalências estratificadas por sexo e nível socioeconômico no programa R. Foram incluídos 12.350 participantes das coortes. Episódio depressivo maior atual foi mais prevalente em adolescentes de São Luís (15,8%; IC95%: 14,8-16,8) e nos adultos de Ribeirão Preto (12,9%; IC95%: 12,0-13,9). As maiores prevalências ...
Journal of Dental Research, 2018
Cadernos de Saúde Pública, 2019
The objective of this study was to analyze the psychometric properties of the hospital birth sati... more The objective of this study was to analyze the psychometric properties of the hospital birth satisfaction scale with data from the first follow-up interview of the Birth in Brazil survey. The 11 questions of the scale were asked by telephone up to six months after discharge in a stratified random sample of 16,109 women residing in all five regions of the country. The sample was randomly divided into two halves. Exploratory factor analysis (EFA) was applied to the first half in order to identify the scale’s factorial structure. The scree plot suggested the scale to be one-dimensional. The EFA demonstrated a good fit of the one-dimensional model. Factor loadings were greater than 0.5 for all items, except for the mean time transpired between leaving the home and arriving at the maternity hospital, which was excluded from the next analysis. The confirmatory factor analysis applied to the sample’s second half with the remaining ten items had a good fit and the factor loadings were > ...
Cadernos de saude publica, Mar 12, 2018
This study estimated the percentages of incomplete immunization with new vaccines and old vaccine... more This study estimated the percentages of incomplete immunization with new vaccines and old vaccines and associated factors in children 13 to 35 months of age belonging to a birth cohort in São Luís, the capital of Maranhão State, Brazil. The sample was probabilistic, with 3,076 children born in 2010. Information on vaccination was obtained from the Child's Health Card. The new vaccines, namely those introduced in 2010, were meningococcal C and 10-valent pneumococcal, and the old vaccines, or those already on the childhood immunization schedule, were BCG, hepatitis B, human rotavirus, polio, tetravalent (diphtheria, tetanus, pertussis, Haemophilus influenzae b), yellow fever, and triple viral (measles, mumps, rubella). The study used hierarchical modeling and Poisson regression with robust variance. Prevalence ratios (PR) and 95% confidence intervals (95%CI) were calculated. Incomplete immunization was higher with new vaccines (51.1%) than with old vaccines (33.2%). Children 25 to...
Pediatrics, Jan 5, 2018
To estimate the baseline prevalence and risk factors for microcephaly at birth before the Zika vi... more To estimate the baseline prevalence and risk factors for microcephaly at birth before the Zika virus epidemic in 2 Brazilian cities. We used population-based data from the Brazilian Ribeirão Preto (RP) and São Luís (SL) birth cohort studies of 2010 that included hospital deliveries by resident mothers. The final sample was 7376 live births in RP and 4220 in SL. Gestational age was based on the date of the mother's last normal menstrual period or obstetric ultrasonography, if available. Microcephaly at birth was classified according to the criteria of the International Fetal and Newborn Growth Consortium for the 21st Century and the Brazilian Ministry of Health. Risk factors for microcephaly, proportionate and disproportionate microcephaly, and severe microcephaly were estimated in a hierarchized logistic regression model. According to the International Fetal and Newborn Growth Consortium for the 21st Century definition, the prevalence of microcephaly (>2 SDs below the mean fo...
Revista brasileira de epidemiologia = Brazilian journal of epidemiology
Several studies have identified social inequalities in low birth weight (LBW), preterm birth (PTB... more Several studies have identified social inequalities in low birth weight (LBW), preterm birth (PTB), and intrauterine growth restriction (IUGR), which, in recent years, have diminished or disappeared in certain locations. Estimate the LBW, PTB, and IUGR rates in São Luís, Maranhão, Brazil, in 2010, and check for associations between socioeconomic factors and these indicators. This study is based on a birth cohort performed in São Luís. It included 5,051 singleton hospital births in 2010. The chi-square test was used for proportion comparisons, while simple and multiple Poisson regression models with robust error variance were used to estimate relative risks. LBW, PTB and IUGR rates were 7.5, 12.2, and 10.3% respectively. LBW was higher in low-income families, while PTB and IUGR were not associated with socioeconomic factors. The absence or weak association of these indicators with social inequality point to improvements in health care and/or in social conditions in São Luís.
Cadernos de saude publica, Jan 13, 2017
This study aimed to investigate the association between maternal depressive symptoms and anxiety ... more This study aimed to investigate the association between maternal depressive symptoms and anxiety and interference in the mother/child relationship, using structural equations modeling. Data were used from a prospective cohort study initiated during the prenatal period with 1,140 mothers in São Luís, Maranhão State, Brazil. Data were collected during prenatal care and when the children reached two years of age. Interference in the mother/child relationship was measured with the Postpartum Bonding Questionnaire - PBQ (N = 1,140). In the initial theoretical model, socioeconomic status determined the maternal demographic, psychosocial, and social support factors, which determined the outcome, i.e., the mother/child relationship. Adjustments were performed by structural equations modeling, using Mplus 7.0. The final model showed good fit (RMSEA = 0.047; CFI = 0.984; TLI = 0.981). Depressive symptoms in pregnancy and the postpartum were associated with higher PBQ scores, indicating interf...
International journal of paediatric dentistry, Jan 21, 2017
A possible association between being overweight or obese and early childhood caries (ECC) remains... more A possible association between being overweight or obese and early childhood caries (ECC) remains controversial. To investigated this association in a developing country testing the confounding effects of socioeconomic factors and frequency of sugar consumption. Historical cohort study, 388 children (aged 24-71 months) living in São Luís, Brazil. A theoretical model adjusted according to income, birthweight, and nutritional status at twelve months and frequency of sugar consumption was generated with directed acyclic graphs to analyze this association. Caries were considered a discrete variable in the Poisson regression models; incidence density ratios (IRs) and 95% confidence intervals (95% CIs) were estimated. Being overweight or obese (IR = 1.52; 95% CI: 1.03-2.22) was independently associated with ECC. Being thin or very thin (IR = 1.97; 95% CI: 1.52-2.54), a high frequency of sugar consumption (IR = 1.83; 95% CI: 1.42-2.38), and age (IR = 3.62; 95% CI: 2.58-5.08) were associate...
Cadernos de saude publica, Jan 23, 2017
The factors associated with physical violence against pregnant women were analyzed in a cross-sec... more The factors associated with physical violence against pregnant women were analyzed in a cross-sectional study of 1,446 pregnant women from a prenatal cohort who were interviewed in 2010 and 2011 in São Luís, Brazil. In the initial model, socioeconomic status occupied the most distal position, determining sociodemographic factors, social support and the behavioral factors that ultimately determined physical violence, which was investigated as a latent variable. Structural equation modeling was used in the analysis. Pregnant women who were from more disadvantaged backgrounds (p = 0.027), did not reside with intimate partners (p = 0.005), had low social support (p < 0.001) and had a high number of lifetime intimate partners (p = 0.001) reported more episodes of physical violence. Low social support was the primary mediator of the effect of socioeconomic status on physical violence. The effect of marital status was mainly mediated by a high number of lifetime intimate partners.
Vulnerable Children and Youth Studies, 2018
Journal of Women's Health, 2021
Background: Few studies have investigated the association between violence against pregnant women... more Background: Few studies have investigated the association between violence against pregnant women in terms of recurrence, complications, and perpetrators of violence, and breastfeeding duration. This study verifies whether recurrent violence, violence with pregnancy complications, and intimate partner violence (IPV) against pregnant women are associated with shorter exclusive breastfeeding up to the infant's 6th month and breastfeeding up to the 12th month of life. Materials and Methods: A cohort study with a convenience sample of 1,146 pregnant women was performed. Follow-up assessments were conducted at birth, and at 12-36 months. Survival analysis was used to verify whether recurrent violence, violence with pregnancy complications, and IPV were associated with reduced duration of exclusive breastfeeding and breastfeeding. Results: The adjusted Cox regression revealed no difference regarding exclusive breastfeeding duration among mothers exposed or not exposed to violence and according to who perpetrated the violence. The risk of an infant not being breastfed within the first 12 months of life increased in cases of violence before/during pregnancy (95% confidence interval [CI] = 1.03-1.88), recurrent psychological/physical/sexual violence during pregnancy (95% CI = 1.11-1.92), recurrent psychological violence (95% CI = 1.05-1.96), and recurrent physical/sexual violence (95% CI = 1.01-2.39). Violence with pregnancy complications (95% CI = 0.94-2.22) was not associated with breastfeeding interruption. Similar risks of breastfeeding interruption were observed for IPV (95% CI = 0.96-1.87) and violence perpetrated by other family members (95% CI = 0.83-1.89). Conclusions: We observed a shorter breastfeeding duration up to 12 months of life in cases of recurrent violence.
O trabalho apresenta o desenvolvimento de um metodo para a identificacao de sementes haploides qu... more O trabalho apresenta o desenvolvimento de um metodo para a identificacao de sementes haploides que possuam o gene marcador R1navajo em milho utilizando a espectroscopia no infravermelho proximo e a analise discriminante por minimos quadrados parciais (PLS-DA). Os espectros de absorbância foram obtidos a partir de 137 sementes de quatro genotipos de milho, na regiao do infravermelho proximo utilizando um equipamento MicroNIR, modelo 1700. A combinacao de Standard Normal Variate - SNV, primeira derivada por Savitzky-Golay e dados centrados na media foi a sequencia de pre-processamento mais eficiente para minimizar os efeitos de espalhamento e deslocamentos da linha de base. O modelo PLS-DA alcancou 100% de classificacoes corretas, considerando os dados de validacao externa para os quatro genotipos de milho avaliados. A analise de parâmetros como sensibilidade, especificidade e eficiencia no conjunto de testes de validacao do modelo resultou em valores iguais a 100% para o conjunto de ...
O objetivo deste trabalho foi avaliar o efeito do avanco de geracoes na obtencao de haploides de ... more O objetivo deste trabalho foi avaliar o efeito do avanco de geracoes na obtencao de haploides de milho em populacoes-fonte de diferentes grupos heteroticos. Os genotipos avaliados foram originados de um campo de inducao de haploidia implantado na Embrapa Milho e Sorgo, em Sete Lagoas, Minas Gerais, em setembro de 2015. Para as avaliacoes, foram utilizadas 10 populacoes-fonte, sendo quatro do grupo heterotico Flint e seis do grupo Dent, nas geracoes F1 e F2. Para inducao, utilizou-se o indutor materno obtido do cruzamento entre plantas do hibrido TAIL P1 x TAIL P2. Para cada populacao-fonte, foram tomadas sete espigas polinizadas manualmente para avaliacao. Foram determinados o numero medio de graos por espiga, o numero de sementes haploides, as taxas de inducao de haploidia e a expressao do gene R1-navajo, dentre outros caracteres. Para comparacao dos dados obtidos entre geracoes e grupos heteroticos, utilizouse o teste de Wilcoxon. Identificou-se um maior numero de haploides em gen...
An analysis was conducted to evaluate if the severity of caries is associated with protein-calori... more An analysis was conducted to evaluate if the severity of caries is associated with protein-calorie malnutrition in preschool children. The cross-sectional study was performed on a retrospective cohort of 625 children aged 24-71 months attending daycare centers in São Luís, Maranhão. A hierarchical model was evaluated at five levels: 1.) Socio-economic variables (economic group, mother's educational level and skin color); 2) Access variables; 3) Low birth weight (LBW) and exclusive breastfeeding; 4) Weight per height at 12 months; and 5) Severity of caries and albumin (Alb) levels. The outcome was protein-calorie malnourishment (weight per height z score < -2). The prevalence of outcome was 5.0% and the prevalence of caries was 32%. At the first level, the variables were not associated with the outcome, but the economic group was maintained until the final model. The variables in the second and third levels were not significant. At the fourth level, weight for height at 12 mon...
International Journal of Infectious Diseases, 2021
Pedigree analysis has long been an essential tool in human genetics as well as a staple of geneti... more Pedigree analysis has long been an essential tool in human genetics as well as a staple of genetics education. Students of genetics might be surprised to learn that human pedigrees were first popularized in the United States by proponents of eugenics, the pseudoscientific social movement aimed at improving the genetic quality of the human race. Notably, the influential eugenicist Charles B. Davenport employed pedigree charts to support his belief that not only were such medical conditions as Huntington disease and albinism inherited in a simple Mendelian fashion, but so too were such characteristics as alcoholism, criminality, and "feeblemindedness." We now see the flaws in Davenport' s pedigree analysis, but at the time, it was the latest scientific advance. The misuse of pedigree analysis during the eugenics era may serve as a cautionary tale for those who are now harnessing the latest genetic technologies to solve complex problems.
Revista Brasileira de Saúde Materno Infantil, 2020
Objectives: to analyze differences in prevalence and perpetrators of violence against women befor... more Objectives: to analyze differences in prevalence and perpetrators of violence against women before and during pregnancy. Methods: this is a cross-sectional study with a sample of 1,446 pregnant women interviewed in 2010 and 2011 in the São Luís municipality (Brazil). Thirteen questions measured psychological, physical and sexual violence in the 12 months before and during pregnancy. Psychological/physical/sexual violence was defined as any type of violence perpetrated against the interviewees. The perpetrators were categorized into intimate partner, other family members, community members, and multiple perpetrators. Differences between violence before and during pregnancy were analyzed by the chi-square test. Results: psychological/physical/sexual and psychological violence were more prevalent during pregnancy than before gestation (p<0.001). Insults, humiliation and intimidation (p<0.05) were more frequently reported during pregnancy. An intimate partner was the most frequent...
Revista Brasileira de Saúde Materno Infantil, 2020
Objectives: to analyze differences in prevalence and perpetrators of violence against women befor... more Objectives: to analyze differences in prevalence and perpetrators of violence against women before and during pregnancy. Methods: this is a cross-sectional study with a sample of 1,446 pregnant women interviewed in 2010 and 2011 in the São Luís municipality (Brazil). Thirteen questions measured psychological, physical and sexual violence in the 12 months before and during pregnancy. Psychological/physical/sexual violence was defined as any type of violence perpetrated against the interviewees. The perpetrators were categorized into intimate partner, other family members, community members, and multiple perpetrators. Differences between violence before and during pregnancy were analyzed by the chi-square test. Results: psychological/physical/sexual and psychological violence were more prevalent during pregnancy than before gestation (p<0.001). Insults, humiliation and intimidation (p<0.05) were more frequently reported during pregnancy. An intimate partner was the most frequent...
Revista Brasileira de Saúde Materno Infantil, 2020
Objectives: to analyze differences in prevalence and perpetrators of violence against women befor... more Objectives: to analyze differences in prevalence and perpetrators of violence against women before and during pregnancy. Methods: this is a cross-sectional study with a sample of 1,446 pregnant women interviewed in 2010 and 2011 in the São Luís municipality (Brazil). Thirteen questions measured psychological, physical and sexual violence in the 12 months before and during pregnancy. Psychological/physical/sexual violence was defined as any type of violence perpetrated against the interviewees. The perpetrators were categorized into intimate partner, other family members, community members, and multiple perpetrators. Differences between violence before and during pregnancy were analyzed by the chi-square test. Results: psychological/physical/sexual and psychological violence were more prevalent during pregnancy than before gestation (p<0.001). Insults, humiliation and intimidation (p<0.05) were more frequently reported during pregnancy. An intimate partner was the most frequent...
Revista do Instituto de Medicina Tropical de São Paulo, 2020
This is an open-access article distributed under the terms of the Creative Commons Attribution Li... more This is an open-access article distributed under the terms of the Creative Commons Attribution License.
Viruses, 2020
The short duration of viremia, low blood viral load, inaccessibility to timely specific diagnosti... more The short duration of viremia, low blood viral load, inaccessibility to timely specific diagnostic tests, and cross-reactions with other flaviviruses have hindered laboratory confirmation of Congenital Zika Syndrome (CZS). This study analyzes the positivity of the plaque reduction neutralization test (PRNT) in children with clinical or imaging characteristics of CZS and its association with laboratory, clinical, and imaging characteristics. The 94 clinical cases of CZS submitted to the ZIKV PRNT90 test were followed from 2016 to 2018. The mean age of children at PRNT90 collection was 22 ± 6 months Standard Deviation. The ZIKV PRNT90 was positive (titer ≥ 10) in 40 (42.5%) children. ZIKV PRNT90 positivity was associated with severe microcephaly in newborns (p = 0.016), lower head circumference z-score at birth (p = 0.043) and 24 months of age (p = 0.031), and severe reduction of the cerebral parenchyma volume (p = 0.021), expressing greater disease severity. Negative PRNT90 in childr...
Cadernos de Saúde Pública, 2020
Resumo: Embora se reconheça que depressão e ansiedade resultem em incapacidades, bem como em prej... more Resumo: Embora se reconheça que depressão e ansiedade resultem em incapacidades, bem como em prejuízos laborais e para os sistemas de saúde, pesquisas de base populacional são escassas no Brasil. Este estudo avaliou a prevalência de transtornos mentais em adolescentes, jovens e adultos e sua relação com características sociodemográficas em cinco coortes de nascimento (RPS): Ribeirão Preto (São Paulo), Pelotas (Rio Grande do Sul) e São Luís (Maranhão), Brasil. Episódio depressivo, risco de suicídio, fobia social e transtorno de ansiedade generalizada foram avaliados usando-se o Mini International Neuropsychiatric Interview. Intervalos de confiança bootstrap foram estimados e prevalências estratificadas por sexo e nível socioeconômico no programa R. Foram incluídos 12.350 participantes das coortes. Episódio depressivo maior atual foi mais prevalente em adolescentes de São Luís (15,8%; IC95%: 14,8-16,8) e nos adultos de Ribeirão Preto (12,9%; IC95%: 12,0-13,9). As maiores prevalências ...
Journal of Dental Research, 2018
Cadernos de Saúde Pública, 2019
The objective of this study was to analyze the psychometric properties of the hospital birth sati... more The objective of this study was to analyze the psychometric properties of the hospital birth satisfaction scale with data from the first follow-up interview of the Birth in Brazil survey. The 11 questions of the scale were asked by telephone up to six months after discharge in a stratified random sample of 16,109 women residing in all five regions of the country. The sample was randomly divided into two halves. Exploratory factor analysis (EFA) was applied to the first half in order to identify the scale’s factorial structure. The scree plot suggested the scale to be one-dimensional. The EFA demonstrated a good fit of the one-dimensional model. Factor loadings were greater than 0.5 for all items, except for the mean time transpired between leaving the home and arriving at the maternity hospital, which was excluded from the next analysis. The confirmatory factor analysis applied to the sample’s second half with the remaining ten items had a good fit and the factor loadings were > ...
Cadernos de saude publica, Mar 12, 2018
This study estimated the percentages of incomplete immunization with new vaccines and old vaccine... more This study estimated the percentages of incomplete immunization with new vaccines and old vaccines and associated factors in children 13 to 35 months of age belonging to a birth cohort in São Luís, the capital of Maranhão State, Brazil. The sample was probabilistic, with 3,076 children born in 2010. Information on vaccination was obtained from the Child's Health Card. The new vaccines, namely those introduced in 2010, were meningococcal C and 10-valent pneumococcal, and the old vaccines, or those already on the childhood immunization schedule, were BCG, hepatitis B, human rotavirus, polio, tetravalent (diphtheria, tetanus, pertussis, Haemophilus influenzae b), yellow fever, and triple viral (measles, mumps, rubella). The study used hierarchical modeling and Poisson regression with robust variance. Prevalence ratios (PR) and 95% confidence intervals (95%CI) were calculated. Incomplete immunization was higher with new vaccines (51.1%) than with old vaccines (33.2%). Children 25 to...
Pediatrics, Jan 5, 2018
To estimate the baseline prevalence and risk factors for microcephaly at birth before the Zika vi... more To estimate the baseline prevalence and risk factors for microcephaly at birth before the Zika virus epidemic in 2 Brazilian cities. We used population-based data from the Brazilian Ribeirão Preto (RP) and São Luís (SL) birth cohort studies of 2010 that included hospital deliveries by resident mothers. The final sample was 7376 live births in RP and 4220 in SL. Gestational age was based on the date of the mother's last normal menstrual period or obstetric ultrasonography, if available. Microcephaly at birth was classified according to the criteria of the International Fetal and Newborn Growth Consortium for the 21st Century and the Brazilian Ministry of Health. Risk factors for microcephaly, proportionate and disproportionate microcephaly, and severe microcephaly were estimated in a hierarchized logistic regression model. According to the International Fetal and Newborn Growth Consortium for the 21st Century definition, the prevalence of microcephaly (>2 SDs below the mean fo...
Revista brasileira de epidemiologia = Brazilian journal of epidemiology
Several studies have identified social inequalities in low birth weight (LBW), preterm birth (PTB... more Several studies have identified social inequalities in low birth weight (LBW), preterm birth (PTB), and intrauterine growth restriction (IUGR), which, in recent years, have diminished or disappeared in certain locations. Estimate the LBW, PTB, and IUGR rates in São Luís, Maranhão, Brazil, in 2010, and check for associations between socioeconomic factors and these indicators. This study is based on a birth cohort performed in São Luís. It included 5,051 singleton hospital births in 2010. The chi-square test was used for proportion comparisons, while simple and multiple Poisson regression models with robust error variance were used to estimate relative risks. LBW, PTB and IUGR rates were 7.5, 12.2, and 10.3% respectively. LBW was higher in low-income families, while PTB and IUGR were not associated with socioeconomic factors. The absence or weak association of these indicators with social inequality point to improvements in health care and/or in social conditions in São Luís.
Cadernos de saude publica, Jan 13, 2017
This study aimed to investigate the association between maternal depressive symptoms and anxiety ... more This study aimed to investigate the association between maternal depressive symptoms and anxiety and interference in the mother/child relationship, using structural equations modeling. Data were used from a prospective cohort study initiated during the prenatal period with 1,140 mothers in São Luís, Maranhão State, Brazil. Data were collected during prenatal care and when the children reached two years of age. Interference in the mother/child relationship was measured with the Postpartum Bonding Questionnaire - PBQ (N = 1,140). In the initial theoretical model, socioeconomic status determined the maternal demographic, psychosocial, and social support factors, which determined the outcome, i.e., the mother/child relationship. Adjustments were performed by structural equations modeling, using Mplus 7.0. The final model showed good fit (RMSEA = 0.047; CFI = 0.984; TLI = 0.981). Depressive symptoms in pregnancy and the postpartum were associated with higher PBQ scores, indicating interf...
International journal of paediatric dentistry, Jan 21, 2017
A possible association between being overweight or obese and early childhood caries (ECC) remains... more A possible association between being overweight or obese and early childhood caries (ECC) remains controversial. To investigated this association in a developing country testing the confounding effects of socioeconomic factors and frequency of sugar consumption. Historical cohort study, 388 children (aged 24-71 months) living in São Luís, Brazil. A theoretical model adjusted according to income, birthweight, and nutritional status at twelve months and frequency of sugar consumption was generated with directed acyclic graphs to analyze this association. Caries were considered a discrete variable in the Poisson regression models; incidence density ratios (IRs) and 95% confidence intervals (95% CIs) were estimated. Being overweight or obese (IR = 1.52; 95% CI: 1.03-2.22) was independently associated with ECC. Being thin or very thin (IR = 1.97; 95% CI: 1.52-2.54), a high frequency of sugar consumption (IR = 1.83; 95% CI: 1.42-2.38), and age (IR = 3.62; 95% CI: 2.58-5.08) were associate...
Cadernos de saude publica, Jan 23, 2017
The factors associated with physical violence against pregnant women were analyzed in a cross-sec... more The factors associated with physical violence against pregnant women were analyzed in a cross-sectional study of 1,446 pregnant women from a prenatal cohort who were interviewed in 2010 and 2011 in São Luís, Brazil. In the initial model, socioeconomic status occupied the most distal position, determining sociodemographic factors, social support and the behavioral factors that ultimately determined physical violence, which was investigated as a latent variable. Structural equation modeling was used in the analysis. Pregnant women who were from more disadvantaged backgrounds (p = 0.027), did not reside with intimate partners (p = 0.005), had low social support (p < 0.001) and had a high number of lifetime intimate partners (p = 0.001) reported more episodes of physical violence. Low social support was the primary mediator of the effect of socioeconomic status on physical violence. The effect of marital status was mainly mediated by a high number of lifetime intimate partners.