Martí Casals - Academia.edu (original) (raw)
Papers by Martí Casals
Archivos De Bronconeumologia, Jul 1, 2023
International Journal of Tuberculosis and Lung Disease, Nov 1, 2013
European Respiratory Journal, Sep 1, 2014
Aim To analyse the differences between patients treated initially with four (HRZE) or three drugs... more Aim To analyse the differences between patients treated initially with four (HRZE) or three drugs (HRZ). Methods We studied 3.189 tuberculosis patients from all the Spanish Autonomous Regions. Frequency distributions for qualitative variables were calculated and proportions were compared between groups using X2 test. Factors associated with 3 or 4 drugs were analysed using logistic regression (backward method) including in the model the variables associated at the bivariate level. Results Conclusions 44,3% patients were treated with 3 drugs. Associated factors with the use of 4 drugs were: immigrants, living in a group, smear positive, HIV infection, being treated in 2009, employed, diagnosed in hospital, and men.
Apunts sports medicine, Apr 1, 2022
Revista Espanola De Salud Publica, Oct 1, 2009
British Journal of Sports Medicine, Mar 5, 2020
BackgroundIt is widely accepted that athletes sustain sports injury if they train ‘too much, too ... more BackgroundIt is widely accepted that athletes sustain sports injury if they train ‘too much, too soon’. However, not all athletes are built the same; some can tolerate more training than others. It is for this reason that prescribing the same training programme to all athletes to reduce injury risk is not optimal from a coaching perspective. Rather, athletes require individualised training plans. In acknowledgement of athlete diversity, it is therefore essential to ask the right causal research question in studies examining sports injury aetiology.PurposeIn this first part of a British Journal of Sports Medicine educational series, we present four different causal research questions related to the ‘too much, too soon’ theory and critically discuss their relevance to sports injury prevention.ContentIf it is true that there is no ‘one size fits all’ training programme, then we need to consider by how much training can vary depending on individual athlete characteristics. To provide an evidence-base for subgroup-specific recommendations, a stronger emphasis on the following questions is needed: (1) How much training is ‘too much’ before athletes with different characteristics sustain sports-related injury? and (2) Does the risk of sports injury differ among athletes with a certain characteristic (eg, high experience) compared with athletes with other characteristics (eg, low experience) depending on how much training they perform?ConclusionWe recommend that sports injury researchers aiming to examine the ‘too much, too soon’ theory should carefully consider how they, assisted by coaches, athletes and clinicians, pose their causal research question. In the light of the limitations of population-based prevention that intends to provide all athletes with the same advice, we argue that a stronger emphasis on research questions targeting subgroups of athletes is needed. In doing so, researchers may assist athletes, clinicians and coaches to understand what training advice/programme works best, for whom and under what circumstances.
... Juan-Pablo Millet1,2,3*, Angels Orcau1,2, Cristina Rius1, Marti Casals1,2,4,5, Patricia Garci... more ... Juan-Pablo Millet1,2,3*, Angels Orcau1,2, Cristina Rius1, Marti Casals1,2,4,5, Patricia Garcia de Olalla1,2, Antonio Moreno1,2, Jeanne L. Nelson1, Joan A. Cayla`1,2,3, the Barcelona Tuberculosis Working Group 1 Epidemiology Service, Public Health Agency of Barcelona ...
Respiratory Research, Dec 1, 2009
PLOS ONE, Jun 11, 2013
<p><b>Barcelona 2003</b>–<b>2009.</b></p
Archivos De Bronconeumologia, May 1, 2016
International and Spanish guidelines recommend a 4-drug regimen in the intensive treatment of tub... more International and Spanish guidelines recommend a 4-drug regimen in the intensive treatment of tuberculosis (TB). The aim of our study was to determine if these recommendations are followed in Spain, and the factors associated with the use of 3 drugs (standard regimen without ethambutol). Observational, multicenter, retrospective analysis of data from patients diagnosed with TB in practically all Spanish Autonomous Communities between 2007 and 2102. Factors associated with the use of 3 drugs were analyzed using logistic regression, and odds ratios (OR) and corresponding 95% confidence intervals (CI) were calculated. A total of 3,189 patients were included, 1,413 (44.3%) of whom received 3 drugs. The percentage of 3-drug users among patients with positive sputum smear was 41.2%; among patients with resistance to at least 1 drug, 36.1%; among HIV-infected patients, 31.4%; and among immigrants, 24.8%. Factors associated with the use of 3 drugs were: female sex (OR=1.18; CI: 1.00-1.39); native Spanish (OR=3.09; CI: 2.58-3.70); retired (OR=1.42; CI: 1.14-1.77); homeless (OR=3.10; CI: 1.52-6.43); living alone (OR=1.62; CI: 1.11-2.36); living in a family (OR=1.97; CI: 1.48-2.65); seen by specialists in the region (OR=1.37; CI: 1.10;1.70); no HIV infection (OR=1.63; CI: 1.09-2.48); and negative sputum smear with positive culture (OR=1.59; CI: 1.25-2.02). A large proportion of TB patients receive intensive treatment with 3 drugs. TB treatment recommendations should be followed, both in routine clinical practice and by the National Plan for Prevention and Control of Tuberculosis in Spain.
British journal of sports medicine, Jan 20, 2017
The British Journal of Sports Medicine has introduced a series of editorials and infographics th... more The British Journal of Sports Medicine has introduced a series of editorials and infographics that explain the value of using appropriate methodology in sports injury research.1–6 Indeed, proper methodology is necessary for understanding why sports injuries develop, how best to prevent them and which therapeutic interventions will be most effective. Without correctly applying and interpreting statistics, subjective intuitions could lead to incorrect conclusions. In this editorial, we present seven common ‘statistical sins’ made in research and discuss how to present research findings in such a way as to help athletes, coaches and clinicians avoid drawing flawed conclusions when attempting to interpret causality in sports injury research. The sins have been adapted from an article originally published in The Conversation .7 Did you know that NFL teams with an animal team logo (eg, Denver Broncos and Carolina Panthers) have a dramatic 15% reduced risk of concussions compared with NFL teams without animal logos (eg, Tennessee Titans and Pittsburgh Steelers)?8 If one looks hard enough, apparently interesting associations and spurious correlations between phenomena can be found almost everywhere. However, simply because two things happen to change in parallel, or follow a similar pattern, does not mean they are causally related. To avoid this sin, one must thoughtfully consider whether the association is likely to be causal or non-causal. Most sports injury studies simply examine non-causal associations, which are sometimes wrongly interpreted as being causal. Think of concussions and animal logos next time you read a sports injury article: are the reported relationships likely to be causally …
<p><b>Barcelona 2003</b>–<b>2009.</b></p
Rev Esp Salud Publica, 2009
Aim To analyse the differences between patients treated initially with four (HRZE) or three drugs... more Aim To analyse the differences between patients treated initially with four (HRZE) or three drugs (HRZ). Methods We studied 3.189 tuberculosis patients from all the Spanish Autonomous Regions. Frequency distributions for qualitative variables were calculated and proportions were compared between groups using X2 test. Factors associated with 3 or 4 drugs were analysed using logistic regression (backward method) including in the model the variables associated at the bivariate level. Results Conclusions 44,3% patients were treated with 3 drugs. Associated factors with the use of 4 drugs were: immigrants, living in a group, smear positive, HIV infection, being treated in 2009, employed, diagnosed in hospital, and men.
The International Journal of Tuberculosis and Lung Disease, 2013
To determine predictive factors for changes in standard anti-tuberculosis chemotherapy at the tim... more To determine predictive factors for changes in standard anti-tuberculosis chemotherapy at the time of diagnosis. M E T H O D S : A prospective study was performed among tuberculosis (TB) patients treated at specialised centres during 2008-2009. Treatment outcome was monitored per standard guidelines. Treatment was considered successful if the patient was cured or completed treatment. Factors associated with treatment modification were analysed at the bivariate and multivariate levels using logistic regression. R E S U LT S : A total of 427 patients were included in the study. The initial standard treatment regimen was retained for 249 patients (58.3%), extended to 9 months for 36 (8.4%) and changed for 142 (33.3%). Factors associated with a change of regimen at the multivariate level were female sex, age ⩾50 years, human immunodeficiency virus infection, comorbidities, alcoholism, hospitalisation and culture-positive sputum. Drug resistance and toxicity were analysed independently. Treatment outcome was successful in 97.2% of cases without a regimen change and in 87.3% of those with a changed regimen (P < 0.001). C O N C L U S I O N : Factors associated with changes in the initial anti-tuberculosis regimen should be considered for rigorous follow-up. Results obtained through individualised treatment provided by specialists were good despite the complexity of the cases treated.
British Journal of Sports Medicine, Mar 10, 2021
ObjectiveWe assessed past-season, pre-season and in-season risk factors to investigate their asso... more ObjectiveWe assessed past-season, pre-season and in-season risk factors to investigate their association with an in-season groin problem in male amateur football players.MethodsPast-season groin-pain information and pre-season short-lever and long-lever adductor squeeze strength were obtained at baseline, together with anthropometrics (weight, lower limb lever length) and player age. In-season hip-related and groin-related sporting function was monitored every 4 weeks using the Sports and Recreation (Sport) subscale from the Hip And Groin Outcome Score questionnaire (HAGOS (Sport)). Groin problems, including time-loss groin injuries and groin pain irrespective of time loss, were collected over a 39-week competitive in-season. We estimated relative risk (RR), and 95% credibility interval (ICr) from logistic regressions fitted in a Bayesian framework.ResultsPlayers (n=245) suffering from groin pain during the past-season had 2.4 times higher risk of experiencing a groin problem in the new season (2.40 RR; 95% ICr 1.5 to 3.7). This risk was reduced by 35% (0.65 RR; 95% ICr 0.42 to 0.99) per unit (N·m/kg) increase in the long-lever adductor squeeze test. Player age, short-lever squeeze test and the HAGOS (Sport) scores were not associated with the risk of a groin problem.ConclusionsPast-season groin pain increased the risk of a groin problem in the new in-season. This risk was reduced by higher pre-season long-lever adductor squeeze strength. Past-season groin-pain information and long-lever adductor squeeze strength can be quickly obtained during pre-season to identify players with an elevated risk of in-season groin problems. This may be key to reduce these problems in the new season.
International Journal of Sports Science & Coaching
A statistical graph can offer an alternative compelling approach to statistical thinking that foc... more A statistical graph can offer an alternative compelling approach to statistical thinking that focuses on important concepts rather than procedural formulas. Nowadays, visualizing multidimensional/multivariate data is essential but can also be challenging. In sport analytics, the exploration and descriptive analysis of data using visualization techniques has increased in recent years to, for example, describe possible patterns and uncertainty of player performance. These visualization techniques have been used so far with different purposes by various professionals in the sport industry, such as managers, coaches, scouters, technical staff, journalists, and researchers. The abuse of graphs, such as the radar plot, and their frequent misinterpretation in the world of sports and possible implications for coaching decisions has led us to create more informative and accurate visualizations. Here, we propose new, more educational visualizations we have termed violinboxplots and enhanced r...
Archivos De Bronconeumologia, Jul 1, 2023
International Journal of Tuberculosis and Lung Disease, Nov 1, 2013
European Respiratory Journal, Sep 1, 2014
Aim To analyse the differences between patients treated initially with four (HRZE) or three drugs... more Aim To analyse the differences between patients treated initially with four (HRZE) or three drugs (HRZ). Methods We studied 3.189 tuberculosis patients from all the Spanish Autonomous Regions. Frequency distributions for qualitative variables were calculated and proportions were compared between groups using X2 test. Factors associated with 3 or 4 drugs were analysed using logistic regression (backward method) including in the model the variables associated at the bivariate level. Results Conclusions 44,3% patients were treated with 3 drugs. Associated factors with the use of 4 drugs were: immigrants, living in a group, smear positive, HIV infection, being treated in 2009, employed, diagnosed in hospital, and men.
Apunts sports medicine, Apr 1, 2022
Revista Espanola De Salud Publica, Oct 1, 2009
British Journal of Sports Medicine, Mar 5, 2020
BackgroundIt is widely accepted that athletes sustain sports injury if they train ‘too much, too ... more BackgroundIt is widely accepted that athletes sustain sports injury if they train ‘too much, too soon’. However, not all athletes are built the same; some can tolerate more training than others. It is for this reason that prescribing the same training programme to all athletes to reduce injury risk is not optimal from a coaching perspective. Rather, athletes require individualised training plans. In acknowledgement of athlete diversity, it is therefore essential to ask the right causal research question in studies examining sports injury aetiology.PurposeIn this first part of a British Journal of Sports Medicine educational series, we present four different causal research questions related to the ‘too much, too soon’ theory and critically discuss their relevance to sports injury prevention.ContentIf it is true that there is no ‘one size fits all’ training programme, then we need to consider by how much training can vary depending on individual athlete characteristics. To provide an evidence-base for subgroup-specific recommendations, a stronger emphasis on the following questions is needed: (1) How much training is ‘too much’ before athletes with different characteristics sustain sports-related injury? and (2) Does the risk of sports injury differ among athletes with a certain characteristic (eg, high experience) compared with athletes with other characteristics (eg, low experience) depending on how much training they perform?ConclusionWe recommend that sports injury researchers aiming to examine the ‘too much, too soon’ theory should carefully consider how they, assisted by coaches, athletes and clinicians, pose their causal research question. In the light of the limitations of population-based prevention that intends to provide all athletes with the same advice, we argue that a stronger emphasis on research questions targeting subgroups of athletes is needed. In doing so, researchers may assist athletes, clinicians and coaches to understand what training advice/programme works best, for whom and under what circumstances.
... Juan-Pablo Millet1,2,3*, Angels Orcau1,2, Cristina Rius1, Marti Casals1,2,4,5, Patricia Garci... more ... Juan-Pablo Millet1,2,3*, Angels Orcau1,2, Cristina Rius1, Marti Casals1,2,4,5, Patricia Garcia de Olalla1,2, Antonio Moreno1,2, Jeanne L. Nelson1, Joan A. Cayla`1,2,3, the Barcelona Tuberculosis Working Group 1 Epidemiology Service, Public Health Agency of Barcelona ...
Respiratory Research, Dec 1, 2009
PLOS ONE, Jun 11, 2013
<p><b>Barcelona 2003</b>–<b>2009.</b></p
Archivos De Bronconeumologia, May 1, 2016
International and Spanish guidelines recommend a 4-drug regimen in the intensive treatment of tub... more International and Spanish guidelines recommend a 4-drug regimen in the intensive treatment of tuberculosis (TB). The aim of our study was to determine if these recommendations are followed in Spain, and the factors associated with the use of 3 drugs (standard regimen without ethambutol). Observational, multicenter, retrospective analysis of data from patients diagnosed with TB in practically all Spanish Autonomous Communities between 2007 and 2102. Factors associated with the use of 3 drugs were analyzed using logistic regression, and odds ratios (OR) and corresponding 95% confidence intervals (CI) were calculated. A total of 3,189 patients were included, 1,413 (44.3%) of whom received 3 drugs. The percentage of 3-drug users among patients with positive sputum smear was 41.2%; among patients with resistance to at least 1 drug, 36.1%; among HIV-infected patients, 31.4%; and among immigrants, 24.8%. Factors associated with the use of 3 drugs were: female sex (OR=1.18; CI: 1.00-1.39); native Spanish (OR=3.09; CI: 2.58-3.70); retired (OR=1.42; CI: 1.14-1.77); homeless (OR=3.10; CI: 1.52-6.43); living alone (OR=1.62; CI: 1.11-2.36); living in a family (OR=1.97; CI: 1.48-2.65); seen by specialists in the region (OR=1.37; CI: 1.10;1.70); no HIV infection (OR=1.63; CI: 1.09-2.48); and negative sputum smear with positive culture (OR=1.59; CI: 1.25-2.02). A large proportion of TB patients receive intensive treatment with 3 drugs. TB treatment recommendations should be followed, both in routine clinical practice and by the National Plan for Prevention and Control of Tuberculosis in Spain.
British journal of sports medicine, Jan 20, 2017
The British Journal of Sports Medicine has introduced a series of editorials and infographics th... more The British Journal of Sports Medicine has introduced a series of editorials and infographics that explain the value of using appropriate methodology in sports injury research.1–6 Indeed, proper methodology is necessary for understanding why sports injuries develop, how best to prevent them and which therapeutic interventions will be most effective. Without correctly applying and interpreting statistics, subjective intuitions could lead to incorrect conclusions. In this editorial, we present seven common ‘statistical sins’ made in research and discuss how to present research findings in such a way as to help athletes, coaches and clinicians avoid drawing flawed conclusions when attempting to interpret causality in sports injury research. The sins have been adapted from an article originally published in The Conversation .7 Did you know that NFL teams with an animal team logo (eg, Denver Broncos and Carolina Panthers) have a dramatic 15% reduced risk of concussions compared with NFL teams without animal logos (eg, Tennessee Titans and Pittsburgh Steelers)?8 If one looks hard enough, apparently interesting associations and spurious correlations between phenomena can be found almost everywhere. However, simply because two things happen to change in parallel, or follow a similar pattern, does not mean they are causally related. To avoid this sin, one must thoughtfully consider whether the association is likely to be causal or non-causal. Most sports injury studies simply examine non-causal associations, which are sometimes wrongly interpreted as being causal. Think of concussions and animal logos next time you read a sports injury article: are the reported relationships likely to be causally …
<p><b>Barcelona 2003</b>–<b>2009.</b></p
Rev Esp Salud Publica, 2009
Aim To analyse the differences between patients treated initially with four (HRZE) or three drugs... more Aim To analyse the differences between patients treated initially with four (HRZE) or three drugs (HRZ). Methods We studied 3.189 tuberculosis patients from all the Spanish Autonomous Regions. Frequency distributions for qualitative variables were calculated and proportions were compared between groups using X2 test. Factors associated with 3 or 4 drugs were analysed using logistic regression (backward method) including in the model the variables associated at the bivariate level. Results Conclusions 44,3% patients were treated with 3 drugs. Associated factors with the use of 4 drugs were: immigrants, living in a group, smear positive, HIV infection, being treated in 2009, employed, diagnosed in hospital, and men.
The International Journal of Tuberculosis and Lung Disease, 2013
To determine predictive factors for changes in standard anti-tuberculosis chemotherapy at the tim... more To determine predictive factors for changes in standard anti-tuberculosis chemotherapy at the time of diagnosis. M E T H O D S : A prospective study was performed among tuberculosis (TB) patients treated at specialised centres during 2008-2009. Treatment outcome was monitored per standard guidelines. Treatment was considered successful if the patient was cured or completed treatment. Factors associated with treatment modification were analysed at the bivariate and multivariate levels using logistic regression. R E S U LT S : A total of 427 patients were included in the study. The initial standard treatment regimen was retained for 249 patients (58.3%), extended to 9 months for 36 (8.4%) and changed for 142 (33.3%). Factors associated with a change of regimen at the multivariate level were female sex, age ⩾50 years, human immunodeficiency virus infection, comorbidities, alcoholism, hospitalisation and culture-positive sputum. Drug resistance and toxicity were analysed independently. Treatment outcome was successful in 97.2% of cases without a regimen change and in 87.3% of those with a changed regimen (P < 0.001). C O N C L U S I O N : Factors associated with changes in the initial anti-tuberculosis regimen should be considered for rigorous follow-up. Results obtained through individualised treatment provided by specialists were good despite the complexity of the cases treated.
British Journal of Sports Medicine, Mar 10, 2021
ObjectiveWe assessed past-season, pre-season and in-season risk factors to investigate their asso... more ObjectiveWe assessed past-season, pre-season and in-season risk factors to investigate their association with an in-season groin problem in male amateur football players.MethodsPast-season groin-pain information and pre-season short-lever and long-lever adductor squeeze strength were obtained at baseline, together with anthropometrics (weight, lower limb lever length) and player age. In-season hip-related and groin-related sporting function was monitored every 4 weeks using the Sports and Recreation (Sport) subscale from the Hip And Groin Outcome Score questionnaire (HAGOS (Sport)). Groin problems, including time-loss groin injuries and groin pain irrespective of time loss, were collected over a 39-week competitive in-season. We estimated relative risk (RR), and 95% credibility interval (ICr) from logistic regressions fitted in a Bayesian framework.ResultsPlayers (n=245) suffering from groin pain during the past-season had 2.4 times higher risk of experiencing a groin problem in the new season (2.40 RR; 95% ICr 1.5 to 3.7). This risk was reduced by 35% (0.65 RR; 95% ICr 0.42 to 0.99) per unit (N·m/kg) increase in the long-lever adductor squeeze test. Player age, short-lever squeeze test and the HAGOS (Sport) scores were not associated with the risk of a groin problem.ConclusionsPast-season groin pain increased the risk of a groin problem in the new in-season. This risk was reduced by higher pre-season long-lever adductor squeeze strength. Past-season groin-pain information and long-lever adductor squeeze strength can be quickly obtained during pre-season to identify players with an elevated risk of in-season groin problems. This may be key to reduce these problems in the new season.
International Journal of Sports Science & Coaching
A statistical graph can offer an alternative compelling approach to statistical thinking that foc... more A statistical graph can offer an alternative compelling approach to statistical thinking that focuses on important concepts rather than procedural formulas. Nowadays, visualizing multidimensional/multivariate data is essential but can also be challenging. In sport analytics, the exploration and descriptive analysis of data using visualization techniques has increased in recent years to, for example, describe possible patterns and uncertainty of player performance. These visualization techniques have been used so far with different purposes by various professionals in the sport industry, such as managers, coaches, scouters, technical staff, journalists, and researchers. The abuse of graphs, such as the radar plot, and their frequent misinterpretation in the world of sports and possible implications for coaching decisions has led us to create more informative and accurate visualizations. Here, we propose new, more educational visualizations we have termed violinboxplots and enhanced r...