Matteo Forlini - Academia.edu (original) (raw)

Papers by Matteo Forlini

Ophthalmology Times, Sep 15, 2015

A group of surgeons were faced with a suprachoroidal hemorrhage following trauma, and decided to ... more A group of surgeons were faced with a suprachoroidal hemorrhage following trauma, and decided to break the ‘rules’ when tackling the case, and came out with surprisingly good results.

Acta Ophthalmologica, Sep 1, 2017

To investigate the effects of vitreoretinal surgery in the management of acute retinal necrosis (... more To investigate the effects of vitreoretinal surgery in the management of acute retinal necrosis (ARN). 17 cases (20 eyes) of ARN had undertaken the surgery, including vitreoretinal surgery for 18 eyes and scleral surgery for 2 eyes. 14 cases (21 eyes) of ARN patients hospitalized at the same period without surgery were used as controls. The follow-up was 5 months to 5 years. 15 eyes in the control group (71.4%) became phthisis bulbi. Useful vision remained in 17 eyes in the surgical group. Retinal detachment is still a severe complication of ARN, and proper vitreoretinal surgery can improve its prognosis.

Applied sciences, Dec 11, 2020

Optical coherence tomography angiography (OCTA) is a non-invasive diagnostic instrument that has ... more Optical coherence tomography angiography (OCTA) is a non-invasive diagnostic instrument that has become indispensable for the management of age-related macular degeneration (AMD). OCTA allows quickly visualizing retinal and choroidal microvasculature, and in the last years, its use

New life after PK and cosmetic IOL implantation in trauma case

Ocular trauma remains a leading cause of visual loss, most often affecting men (on average, five ... more Ocular trauma remains a leading cause of visual loss, most often affecting men (on average, five males are affected to one female). The incidence has been estimated as 3:10.000 of population (Tielsch and Parver 1990; Canavan et al. 1980). Severe injuries account for 5 % of all eye injuries (Schein et al. 1988). The clinical characteristics vary widely. Intraocular foreign bodies (IOFB) are common in war (Ahmadieh et al. 1993) and road traffic accidents. In children, sharp objects are most commonly implicated, and the complication of amblyopia limits visual recovery (Alfaro et al. 1994).

Investigative Ophthalmology & Visual Science, Apr 28, 2009

Current Concepts and Management of Eye Injuries, 2016

Posttraumatic infectious endophthalmitis is a rare but very severe complication of ocular trauma.... more Posttraumatic infectious endophthalmitis is a rare but very severe complication of ocular trauma. Its occurrence aggravates visual prognosis of traumatized eyes. The US Eye Injury Registry reports showed that 3.4 % cases of open-globe injuries are associated with endophthalmitis (Danis 2002). Despite advances in the use of intraocular antibiotics, infection resulting from penetrating ocular trauma continues to present a clinical challenge. It remains an important cause of visual failure following open-globe injuries and may complicate seemingly benign injuries such as small, self-sealing corneal laceration without associated intraocular damage. Microbial inoculation of the aqueous fluid and vitreous gel with subsequent proliferation of these organisms yields a vigorous immune response. Optic nerve, ciliary body, retina, and other ocular structures and also invading pathogens release toxins that cause damage to ocular structures. Prompt antibiotic treatment is recommended by ophthalmologist when traumatic endophthalmitis is suspected (Meredith 1999; Soheilian et al. 2001).

Journal of Ophthalmology, 2020

Purpose. To evaluate whether limited vitrectomy is as effective as complete vitrectomy in eyes wi... more Purpose. To evaluate whether limited vitrectomy is as effective as complete vitrectomy in eyes with epiretinal membrane (ERM) and to compare the surgical times and rates of complications. Methods. In this multicentre European study, data of eyes with ERM that underwent vitrectomy from January 2017 to July 2018 were analyzed retrospectively. In the limited vitrectomy group, a posterior vitreous detachment (PVD) was induced up till the equator as opposed to complete PVD induction till the vitreous base in the comparison group. Incidence of iatrogenic retinal breaks, retinal detachment, surgical time, and visual outcomes were compared between groups. Results. We included 139 eyes in the analysis with a mean age being 72.2 ± 6.9 years. In this, sixty-five eyes (47%) underwent limited vitrectomy and 74 eyes (53%) underwent complete vitrectomy. Iatrogenic retinal tears were seen in both groups (5% in limited vitrectomy versus 7% in complete vitrectomy, p = 0.49 ). Retinal detachment occur...

SCOPO: Valutare gli aspetti morfologici-strutturali delle incisioni e della capsuloressi in pazie... more SCOPO: Valutare gli aspetti morfologici-strutturali delle incisioni e della capsuloressi in pazienti sottoposti ad intervento di asportazione di cataratta con tecnica B-MICS (bimanual micro incision cataract surgery) in rapporto ai risultati clinici ottenuti.MATERIALI E METODI: \uc8 stata analizzata, presso la Struttura Complessa di Oftalmologia dell\u2019Universit\ue0 di Modena e Reggio Emilia, una serie aperta di 80 occhi di 48 pazienti operati di cataratta con tecnica B-MICS dopo 3-6 mesi dall\u2019intervento.I pazienti sono stati sottoposti ad una fotografia del segmento anteriore alla lampada a fessura per evidenziare la linea di ressi e sono stati suddivisi in 3 gruppi in base al diametro della capsuloressi: piccola ( 6,00 mm). Inoltre si sono sottoposti a studio con OCT del segmento anteriore (Nidek RS3000) per valutare l\u2019architettura delle microincisioni di accesso corneale, comparando le incisioni secondo due modalit\ue0: mano destra vs. mano sinistra del chirurgo ed incisioni sul versante nasale vs. incisioni temporali.RISULTATI: L\u2019analisi della capsuloressi \ue8 stata possibile in 59 occhi: 14 con capsuloressi piccole, 21 medie, 24 grandi; l\u2019acuit\ue0 visiva media nel gruppo di pazienti con ressi grande era di 9,71/10 \ub1 0,06, con correzione di 0.00 \ub1 0,68 diottrie; nel gruppo con ressi media era di 9,6/10 \ub1 0,09 con correzione di - 0,08 \ub1 0,66 diottrie; nel gruppo con ressi piccola era di 9,75/10 \ub10,09 con correzione di -0,16 \ub1 0,48 diottrie.Lo studio delle microincisioni mediante OCT del segmento anteriore \ue8 stato eseguito in 52 occhi. Nel confronto mano destra (dominante) e mano sinistra (non dominante) i valori per la mano destra sono stati: 709,75 \u3bcm di spessore corneale, 1427,91 \u3bcm di lunghezza dell\u2019incisione e 31, 19\ub0 di angolo rispetto alla tangente corneale, i valori per la mano sinistra sono stati: 724,56 \u3bcm di spessore corneale, 1440,63 \u3bcm di lunghezza dell\u2019incisione e 31,54\ub0 di angolo rispetto alla tangente corneale. Nel confronto tra incisioni nasali e temporali i valori per le incisioni nasali sono stati: 710, 35 \u3bcm di spessore corneale, 1394,41 \u3bcm di lunghezza dell\u2019incisione e 31,46\ub0 di angolo rispetto alla tangente corneale, i valori per l\u2019incisione temporale sono stati: 723,96 \u3bcm di spessore corneale, 1474,13 \u3bcm di lunghezza dell\u2019incisione e 31,27\ub0 di angolo rispetto la tangente corneale.CONCLUSIONI: L\u2019acuit\ue0 visiva dei pazienti non mostra una differenza significativa nei tre diversi gruppi dimensionali di capsuloressi: il diametro della ressi eseguita non appare quindi un fattore determinante per il raggiungimento di una acuit\ue0 visiva ottimale.Per quanto riguarda le microincisioni, non emergono differenze statisticamente significative nella loro struttura confrontando quelle eseguite con la mano dominante con quelle eseguite con la mano non dominante, n\ue9 emerge una differenza statisticamente significativa nella struttura fra le incisioni nasali rispetto a quelle temporali

2022 18th IEEE/ASME International Conference on Mechatronic and Embedded Systems and Applications (MESA)

European Journal of Ophthalmology, 2011

Journal of Genetic Syndromes & Gene Therapy, 2013

Background: Dismetabolic cataract is a loss of lens transparency due to an insult to the nuclear ... more Background: Dismetabolic cataract is a loss of lens transparency due to an insult to the nuclear or lenticular fibers, caused by a metabolic disorder. The lens opacification may occur early or later in life, and may be isolated or associated to particular syndromes. We describe some of these metabolic conditions associated with cataract formation, and in particular we report our experience with a patient affected by lathosterolosis that presented bilateral cataracts. Methods: Our patient was a 7-years-old little girl diagnosed with lathosterolosis at age 2 years, through gas cromatography/mass spectrometry method for plasma sterol profile that revealed a peak corresponding to cholest-7-en-3β-ol (lathosterol).

Journal of Genetic Syndromes & Gene Therapy, 2013

Optic nerve aplasia is an extremely rare anomaly that is usually associated with microphthalmos a... more Optic nerve aplasia is an extremely rare anomaly that is usually associated with microphthalmos as well as with other ocular and extraocular anomalies. In this case report we describe a case of an occasional finding of unilateral complete aplasia of the optic nerve in girl at the age of 42 days, in association only with microphthalmos. Figure 1: RetCam fundus examination of OD revealing a dysplastic retina with complete absence of retinal vessels, optic nerve and optic disc.

Ophthalmology: Current and Future Developments, 2017

Journal of Cataract and Refractive Surgery

Cataract surgery via phacoemulsification with intraocular lens (IOL) placement in the capsular ba... more Cataract surgery via phacoemulsification with intraocular lens (IOL) placement in the capsular bag is the gold standard in the presence of adequate capsular support. However, when capsule and/or zonules are weak or absent, alternate fixation strategies are required. Common alternative options include retropupillary iris-claw IOLs (RP-ICIOLs) and scleral-fixated IOLs (SFIOLs). In the present review of 87 papers with 2174 eyes implanted with RP-ICIOL and 2980 eyes with SFIOL, we discuss the published literature of SFIOLs and RP-ICIOLs with respect to safety and efficacy. Although, the studies reporting outcomes of these IOLs have been performed in patients with different concomitant conditions, visual and refractive outcomes were found to be comparable between RP-ICIOL and SFIOLs. RP-ICIOL implantation seemed to provide equivalent or potentially lower rate of complications than SFIOL implantation. Data from literature also suggest that the surgical technique of RP-ICIOL implantation is relatively simpler with correspondingly shorter surgical time.

Applied Sciences

Background: To study the safety and efficacy provided by a minimal and localized anesthesia in ca... more Background: To study the safety and efficacy provided by a minimal and localized anesthesia in cataract surgery. Methods: Randomized controlled trial. A total of 100 patients undergoing cataract surgery were randomly divided into two groups of 50, which respecitvely received conventional topical anesthesia consisting of preservative-free Oxibuprocaine hydrochloride 0.4% drops or minimal localized anesthesia, administered with a cotton bud soaked in preservative-free Oxibuprocaine hydrochloride 0.4% applied to clear cornea on the access sites for 10 s immediately before surgery. The mean outcome measures were intraoperative pain and the incidence of postoperative ocular discomfort. Results: All patients tolerated well the procedure, giving patin scores between 1–3. Fifteen patients (30%) of group 1 and ten of group 2 (25%) required supplemental anesthesia. No intraoperative complications were recorded. No eyes had epithelial defects at the end of the surgery or at postoperative check...

Cutting-edge Vitreoretinal Surgery

Ophthalmology Times, Sep 15, 2015

A group of surgeons were faced with a suprachoroidal hemorrhage following trauma, and decided to ... more A group of surgeons were faced with a suprachoroidal hemorrhage following trauma, and decided to break the ‘rules’ when tackling the case, and came out with surprisingly good results.

Acta Ophthalmologica, Sep 1, 2017

To investigate the effects of vitreoretinal surgery in the management of acute retinal necrosis (... more To investigate the effects of vitreoretinal surgery in the management of acute retinal necrosis (ARN). 17 cases (20 eyes) of ARN had undertaken the surgery, including vitreoretinal surgery for 18 eyes and scleral surgery for 2 eyes. 14 cases (21 eyes) of ARN patients hospitalized at the same period without surgery were used as controls. The follow-up was 5 months to 5 years. 15 eyes in the control group (71.4%) became phthisis bulbi. Useful vision remained in 17 eyes in the surgical group. Retinal detachment is still a severe complication of ARN, and proper vitreoretinal surgery can improve its prognosis.

Applied sciences, Dec 11, 2020

Optical coherence tomography angiography (OCTA) is a non-invasive diagnostic instrument that has ... more Optical coherence tomography angiography (OCTA) is a non-invasive diagnostic instrument that has become indispensable for the management of age-related macular degeneration (AMD). OCTA allows quickly visualizing retinal and choroidal microvasculature, and in the last years, its use

New life after PK and cosmetic IOL implantation in trauma case

Ocular trauma remains a leading cause of visual loss, most often affecting men (on average, five ... more Ocular trauma remains a leading cause of visual loss, most often affecting men (on average, five males are affected to one female). The incidence has been estimated as 3:10.000 of population (Tielsch and Parver 1990; Canavan et al. 1980). Severe injuries account for 5 % of all eye injuries (Schein et al. 1988). The clinical characteristics vary widely. Intraocular foreign bodies (IOFB) are common in war (Ahmadieh et al. 1993) and road traffic accidents. In children, sharp objects are most commonly implicated, and the complication of amblyopia limits visual recovery (Alfaro et al. 1994).

Investigative Ophthalmology & Visual Science, Apr 28, 2009

Current Concepts and Management of Eye Injuries, 2016

Posttraumatic infectious endophthalmitis is a rare but very severe complication of ocular trauma.... more Posttraumatic infectious endophthalmitis is a rare but very severe complication of ocular trauma. Its occurrence aggravates visual prognosis of traumatized eyes. The US Eye Injury Registry reports showed that 3.4 % cases of open-globe injuries are associated with endophthalmitis (Danis 2002). Despite advances in the use of intraocular antibiotics, infection resulting from penetrating ocular trauma continues to present a clinical challenge. It remains an important cause of visual failure following open-globe injuries and may complicate seemingly benign injuries such as small, self-sealing corneal laceration without associated intraocular damage. Microbial inoculation of the aqueous fluid and vitreous gel with subsequent proliferation of these organisms yields a vigorous immune response. Optic nerve, ciliary body, retina, and other ocular structures and also invading pathogens release toxins that cause damage to ocular structures. Prompt antibiotic treatment is recommended by ophthalmologist when traumatic endophthalmitis is suspected (Meredith 1999; Soheilian et al. 2001).

Journal of Ophthalmology, 2020

Purpose. To evaluate whether limited vitrectomy is as effective as complete vitrectomy in eyes wi... more Purpose. To evaluate whether limited vitrectomy is as effective as complete vitrectomy in eyes with epiretinal membrane (ERM) and to compare the surgical times and rates of complications. Methods. In this multicentre European study, data of eyes with ERM that underwent vitrectomy from January 2017 to July 2018 were analyzed retrospectively. In the limited vitrectomy group, a posterior vitreous detachment (PVD) was induced up till the equator as opposed to complete PVD induction till the vitreous base in the comparison group. Incidence of iatrogenic retinal breaks, retinal detachment, surgical time, and visual outcomes were compared between groups. Results. We included 139 eyes in the analysis with a mean age being 72.2 ± 6.9 years. In this, sixty-five eyes (47%) underwent limited vitrectomy and 74 eyes (53%) underwent complete vitrectomy. Iatrogenic retinal tears were seen in both groups (5% in limited vitrectomy versus 7% in complete vitrectomy, p = 0.49 ). Retinal detachment occur...

SCOPO: Valutare gli aspetti morfologici-strutturali delle incisioni e della capsuloressi in pazie... more SCOPO: Valutare gli aspetti morfologici-strutturali delle incisioni e della capsuloressi in pazienti sottoposti ad intervento di asportazione di cataratta con tecnica B-MICS (bimanual micro incision cataract surgery) in rapporto ai risultati clinici ottenuti.MATERIALI E METODI: \uc8 stata analizzata, presso la Struttura Complessa di Oftalmologia dell\u2019Universit\ue0 di Modena e Reggio Emilia, una serie aperta di 80 occhi di 48 pazienti operati di cataratta con tecnica B-MICS dopo 3-6 mesi dall\u2019intervento.I pazienti sono stati sottoposti ad una fotografia del segmento anteriore alla lampada a fessura per evidenziare la linea di ressi e sono stati suddivisi in 3 gruppi in base al diametro della capsuloressi: piccola ( 6,00 mm). Inoltre si sono sottoposti a studio con OCT del segmento anteriore (Nidek RS3000) per valutare l\u2019architettura delle microincisioni di accesso corneale, comparando le incisioni secondo due modalit\ue0: mano destra vs. mano sinistra del chirurgo ed incisioni sul versante nasale vs. incisioni temporali.RISULTATI: L\u2019analisi della capsuloressi \ue8 stata possibile in 59 occhi: 14 con capsuloressi piccole, 21 medie, 24 grandi; l\u2019acuit\ue0 visiva media nel gruppo di pazienti con ressi grande era di 9,71/10 \ub1 0,06, con correzione di 0.00 \ub1 0,68 diottrie; nel gruppo con ressi media era di 9,6/10 \ub1 0,09 con correzione di - 0,08 \ub1 0,66 diottrie; nel gruppo con ressi piccola era di 9,75/10 \ub10,09 con correzione di -0,16 \ub1 0,48 diottrie.Lo studio delle microincisioni mediante OCT del segmento anteriore \ue8 stato eseguito in 52 occhi. Nel confronto mano destra (dominante) e mano sinistra (non dominante) i valori per la mano destra sono stati: 709,75 \u3bcm di spessore corneale, 1427,91 \u3bcm di lunghezza dell\u2019incisione e 31, 19\ub0 di angolo rispetto alla tangente corneale, i valori per la mano sinistra sono stati: 724,56 \u3bcm di spessore corneale, 1440,63 \u3bcm di lunghezza dell\u2019incisione e 31,54\ub0 di angolo rispetto alla tangente corneale. Nel confronto tra incisioni nasali e temporali i valori per le incisioni nasali sono stati: 710, 35 \u3bcm di spessore corneale, 1394,41 \u3bcm di lunghezza dell\u2019incisione e 31,46\ub0 di angolo rispetto alla tangente corneale, i valori per l\u2019incisione temporale sono stati: 723,96 \u3bcm di spessore corneale, 1474,13 \u3bcm di lunghezza dell\u2019incisione e 31,27\ub0 di angolo rispetto la tangente corneale.CONCLUSIONI: L\u2019acuit\ue0 visiva dei pazienti non mostra una differenza significativa nei tre diversi gruppi dimensionali di capsuloressi: il diametro della ressi eseguita non appare quindi un fattore determinante per il raggiungimento di una acuit\ue0 visiva ottimale.Per quanto riguarda le microincisioni, non emergono differenze statisticamente significative nella loro struttura confrontando quelle eseguite con la mano dominante con quelle eseguite con la mano non dominante, n\ue9 emerge una differenza statisticamente significativa nella struttura fra le incisioni nasali rispetto a quelle temporali

2022 18th IEEE/ASME International Conference on Mechatronic and Embedded Systems and Applications (MESA)

European Journal of Ophthalmology, 2011

Journal of Genetic Syndromes & Gene Therapy, 2013

Background: Dismetabolic cataract is a loss of lens transparency due to an insult to the nuclear ... more Background: Dismetabolic cataract is a loss of lens transparency due to an insult to the nuclear or lenticular fibers, caused by a metabolic disorder. The lens opacification may occur early or later in life, and may be isolated or associated to particular syndromes. We describe some of these metabolic conditions associated with cataract formation, and in particular we report our experience with a patient affected by lathosterolosis that presented bilateral cataracts. Methods: Our patient was a 7-years-old little girl diagnosed with lathosterolosis at age 2 years, through gas cromatography/mass spectrometry method for plasma sterol profile that revealed a peak corresponding to cholest-7-en-3β-ol (lathosterol).

Journal of Genetic Syndromes & Gene Therapy, 2013

Optic nerve aplasia is an extremely rare anomaly that is usually associated with microphthalmos a... more Optic nerve aplasia is an extremely rare anomaly that is usually associated with microphthalmos as well as with other ocular and extraocular anomalies. In this case report we describe a case of an occasional finding of unilateral complete aplasia of the optic nerve in girl at the age of 42 days, in association only with microphthalmos. Figure 1: RetCam fundus examination of OD revealing a dysplastic retina with complete absence of retinal vessels, optic nerve and optic disc.

Ophthalmology: Current and Future Developments, 2017

Journal of Cataract and Refractive Surgery

Cataract surgery via phacoemulsification with intraocular lens (IOL) placement in the capsular ba... more Cataract surgery via phacoemulsification with intraocular lens (IOL) placement in the capsular bag is the gold standard in the presence of adequate capsular support. However, when capsule and/or zonules are weak or absent, alternate fixation strategies are required. Common alternative options include retropupillary iris-claw IOLs (RP-ICIOLs) and scleral-fixated IOLs (SFIOLs). In the present review of 87 papers with 2174 eyes implanted with RP-ICIOL and 2980 eyes with SFIOL, we discuss the published literature of SFIOLs and RP-ICIOLs with respect to safety and efficacy. Although, the studies reporting outcomes of these IOLs have been performed in patients with different concomitant conditions, visual and refractive outcomes were found to be comparable between RP-ICIOL and SFIOLs. RP-ICIOL implantation seemed to provide equivalent or potentially lower rate of complications than SFIOL implantation. Data from literature also suggest that the surgical technique of RP-ICIOL implantation is relatively simpler with correspondingly shorter surgical time.

Applied Sciences

Background: To study the safety and efficacy provided by a minimal and localized anesthesia in ca... more Background: To study the safety and efficacy provided by a minimal and localized anesthesia in cataract surgery. Methods: Randomized controlled trial. A total of 100 patients undergoing cataract surgery were randomly divided into two groups of 50, which respecitvely received conventional topical anesthesia consisting of preservative-free Oxibuprocaine hydrochloride 0.4% drops or minimal localized anesthesia, administered with a cotton bud soaked in preservative-free Oxibuprocaine hydrochloride 0.4% applied to clear cornea on the access sites for 10 s immediately before surgery. The mean outcome measures were intraoperative pain and the incidence of postoperative ocular discomfort. Results: All patients tolerated well the procedure, giving patin scores between 1–3. Fifteen patients (30%) of group 1 and ten of group 2 (25%) required supplemental anesthesia. No intraoperative complications were recorded. No eyes had epithelial defects at the end of the surgery or at postoperative check...

Cutting-edge Vitreoretinal Surgery