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Research paper thumbnail of Expedient Synthesis of MLN1251, A CCR5 Antagonist for Treatment of HIV

Organic Process Research & Development, 2007

An expedient synthesis of MLN1251 has been developed that allows for the production of multikilog... more An expedient synthesis of MLN1251 has been developed that allows for the production of multikilogram quantities of the target compound. The key transformation is synthesis of a 5-hydroxyindole by a Nenitzescu reaction. The longest linear sequence is five steps with an ...

Research paper thumbnail of Dithiocarbamate-Functionalized Dendrimers as Ligands for Metal Complexes

Inorganic Chemistry, 1998

Zeroth- and first-generation poly(amido)amine dendrimers have been functionalized with dithiocarb... more Zeroth- and first-generation poly(amido)amine dendrimers have been functionalized with dithiocarbamate end groups and reacted with ruthenium complexes, to form metallodendrimers. Monomeric ruthenium dithiocarbamate complexes were also prepared as model compounds and their spectroscopic data compared with those of the metallodendrimers. The novel compounds were characterized using NMR spectroscopy ((1)H and (13)C) and mass spectrometry. The compound [Ru(S(2)CNMe(2))(PPh(3))(eta(5)-C(5)H(5))] has also been characterized crystallographically.

Research paper thumbnail of ChemInform Abstract: Rhodium-Catalyzed Hydroformylation and Carbonylation of N-Alkenyl-1,3-diaminopropanes

Research paper thumbnail of The stereochemistry of organometallic compounds. XIII. The 13 C N.M.R. spectra of some Tricarbonyl(arene)chromium compounds

Australian Journal of Chemistry, 1975

... XXX* Hydrocyanation of Alkynol Ethers: a New Stereospecific Route to a-Alkylidene y-Lactones?... more ... XXX* Hydrocyanation of Alkynol Ethers: a New Stereospecific Route to a-Alkylidene y-Lactones? W; Roy Jackson, Patrick Perlmutter and Andrew J. Smallridge Department of Chemistry, Monash University, Clayton, Vic. ... Soc., 1950, 230. l1 Samsel, EG, and Norton, J. R., J. Am. ...

Research paper thumbnail of Star porphyrazines and related multimetallic macrocycles

Journal of Heterocyclic Chemistry, 1998

Page 1. Sep-Oct 1998 Star Porphyrazines and Related Multimetallic Macrocycles К. Andersen [a], M.... more Page 1. Sep-Oct 1998 Star Porphyrazines and Related Multimetallic Macrocycles К. Andersen [a], M. Anderson [b], О. P. Anderson [a], S. Baum [с], TF Baumann [b], LS Beali [с], WE Broderick [b], AS Cook [c], DM Eichhorn [b], D ...

Research paper thumbnail of Expedient Synthesis of MLN1251, A CCR5 Antagonist for Treatment of HIV

Organic Process Research & Development, 2007

An expedient synthesis of MLN1251 has been developed that allows for the production of multikilog... more An expedient synthesis of MLN1251 has been developed that allows for the production of multikilogram quantities of the target compound. The key transformation is synthesis of a 5-hydroxyindole by a Nenitzescu reaction. The longest linear sequence is five steps with an ...

Research paper thumbnail of Dithiocarbamate-Functionalized Dendrimers as Ligands for Metal Complexes

Inorganic Chemistry, 1998

Zeroth- and first-generation poly(amido)amine dendrimers have been functionalized with dithiocarb... more Zeroth- and first-generation poly(amido)amine dendrimers have been functionalized with dithiocarbamate end groups and reacted with ruthenium complexes, to form metallodendrimers. Monomeric ruthenium dithiocarbamate complexes were also prepared as model compounds and their spectroscopic data compared with those of the metallodendrimers. The novel compounds were characterized using NMR spectroscopy ((1)H and (13)C) and mass spectrometry. The compound [Ru(S(2)CNMe(2))(PPh(3))(eta(5)-C(5)H(5))] has also been characterized crystallographically.

Research paper thumbnail of ChemInform Abstract: Rhodium-Catalyzed Hydroformylation and Carbonylation of N-Alkenyl-1,3-diaminopropanes

Research paper thumbnail of The stereochemistry of organometallic compounds. XIII. The 13 C N.M.R. spectra of some Tricarbonyl(arene)chromium compounds

Australian Journal of Chemistry, 1975

... XXX* Hydrocyanation of Alkynol Ethers: a New Stereospecific Route to a-Alkylidene y-Lactones?... more ... XXX* Hydrocyanation of Alkynol Ethers: a New Stereospecific Route to a-Alkylidene y-Lactones? W; Roy Jackson, Patrick Perlmutter and Andrew J. Smallridge Department of Chemistry, Monash University, Clayton, Vic. ... Soc., 1950, 230. l1 Samsel, EG, and Norton, J. R., J. Am. ...

Research paper thumbnail of Star porphyrazines and related multimetallic macrocycles

Journal of Heterocyclic Chemistry, 1998

Page 1. Sep-Oct 1998 Star Porphyrazines and Related Multimetallic Macrocycles К. Andersen [a], M.... more Page 1. Sep-Oct 1998 Star Porphyrazines and Related Multimetallic Macrocycles К. Andersen [a], M. Anderson [b], О. P. Anderson [a], S. Baum [с], TF Baumann [b], LS Beali [с], WE Broderick [b], AS Cook [c], DM Eichhorn [b], D ...

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