Mehmet Kır - Academia.edu (original) (raw)
Papers by Mehmet Kır
Journal of Comparative Physiology B
Süleyman Demirel Üniversitesi Eğirdir Su Ürünleri Fakültesi dergisi, Jan 4, 2006
Bu çalışmada, üç farklı büyüklükte (1, 5 ve 10 g) gökkuşağı alabalığı (Oncorhynchus mykiss) yavru... more Bu çalışmada, üç farklı büyüklükte (1, 5 ve 10 g) gökkuşağı alabalığı (Oncorhynchus mykiss) yavrularının, 13°C su sıcaklığında ve pH 7.0 seviyesinde, amonyak LC 50 değerleri tespit edilmiştir. Ayrıca balık büyüklüğü ile türün 24, 48, 72 ve 96 saatlik amonyak LC 50 değerleri arasındaki ilişki belirlenmiştir. Toplam Amonyak Nitrojeni (TAN) için 96 saatlik LC 50 değerleri 1, 5 ve 10 g balık yavrularında, sırasıyla 10.57 mg/L, 3.39 mg/L ve 2.50 mg/L olarak tespit edilmiştir. Her ağırlık grubu için, güvenli üst TAN seviyesi sırasıyla 1.05 mg/L, 0.33 mg/L ve 0.25 mg/L olarak hesaplanmıştır. Çalışma sonuçları balık ağırlığının artmasıyla amonyak LC 50 değerinin azaldığını göstermiştir.
Journal of Thermal Biology
TEZ5014Tez (Doktora) -- Çukurova Üniversitesi, Adana, 2004.Kaynakça (s. 89-102) var.ix, 101 s. ; ... more TEZ5014Tez (Doktora) -- Çukurova Üniversitesi, Adana, 2004.Kaynakça (s. 89-102) var.ix, 101 s. ; 30 cm.
Journal of the World Aquaculture Society, 2017
Sea bream, Sparus aurata, is one of the most important fish species that is commonly cultured in ... more Sea bream, Sparus aurata, is one of the most important fish species that is commonly cultured in the Mediterranean and the eastern coasts of the Atlantic Ocean. The life cycle of sea bream in its natural habitat passes through hyposaline and hypersaline lagoons. It is important to determine the tolerance of the fish to nitrogenous compounds for aquaculture at maximum stocking densities. In the present study, a series of acute experiments were performed to evaluate the effect of salinity on ammonia and nitrite toxicity to sea bream. The fish were exposed to different ammonia and nitrite concentrations according to the static renewal methodology at three different salinities (10, 20, and 30 ppt) and at a temperature of 20 C and a pH of 8.2. The toxic effect of total ammonia nitrogen (TAN) and nitrite nitrogen (NO 2-N) decreased with increasing salinity levels (P < 0.001). Acute toxicity (96-h lethal concentration 50 [LC 50 ]) values of TAN were determined to be 5.93, 11.72, and 19.38 mg/L at 10, 20, and 30 ppt salinity, respectively. The 96-h LC 50 values of NO 2-N were determined to be 370.80, 619.47, and 806.33 mg/L at 10, 20, and 30 ppt salinity, respectively. Results indicate that sea bream is less tolerant to ammonia but more tolerant to nitrite compared with some other fish species.
Journal of the World Aquaculture Society, 2015
Meagre, Argyrosomus regius, is a candidate marine fish species for aquaculture diversification, p... more Meagre, Argyrosomus regius, is a candidate marine fish species for aquaculture diversification, presenting a high economic value in the Mediterranean. Tolerance of juvenile meagre to nitrite (NO 2-N) was determined relating to temperature. Fish (3.2 ± 0.6 g and 5.4 ± 0.9 cm) were exposed to different NO 2-N concentrations in a series of acute toxicity tests by the static renewal method at three temperatures (18, 22, and 26 C) at a pH of 8.0. Low temperature clearly increased tolerance to NO 2-N (P < 0.05). The 96-h median lethal concentration (LC 50) values of NO 2-N were 177.63, 139.55, and 49.61 mg/L, at 18, 22, and 26 C, respectively. The safe levels of NO 2-N for juvenile meagre were estimated to be 17.7, 13.9, and 4.9 mg/L at 18, 22, and 26 C, respectively (P < 0.05). This study indicates A. regius is more sensitive to nitrite than other marine fish species cultured in the Mediterranean.
Aquaculture Research, 2015
Argyrosomus regius (3.0 ± 0.9 g) were exposed to different concentrations of ammonia in a series ... more Argyrosomus regius (3.0 ± 0.9 g) were exposed to different concentrations of ammonia in a series of acute toxicity tests by the static renewal method at three temperature levels (18, 22 and 26°C) at a pH of 8.2. Low temperature clearly increased the tolerance of the fish to total ammonia nitrogen (TAN) and unionized ammonia (NH3) (P < 0.05). While the 96-h LC50 values of TAN were 19.79, 10.39 and 5.06 mg L−1, the 96-h LC50 of NH3 were 1.00, 0.70 and 0.44 mg L−1 at 18, 22 and 26°C respectively. The safe levels of NH3 for A. regius was estimated to be 0.10, 0.07 and 0.04 mg L−1 at 18, 22 and 26°C respectively (P < 0.05). This study clearly indicates that A. regius is more sensitive to ammonia than other marine fish species cultured on the Mediterranean and Eastern Atlantic coasts.
Aquaculture Research, 2005
The European sea bass (Dicentrarchus labrax L.) is an economically important euryhaline marine fi... more The European sea bass (Dicentrarchus labrax L.) is an economically important euryhaline marine fish that frequently inhabits coastal waters of the Mediterranean Sea and is capable of tolerating both hypersaline and freshwater (FW) environments (Eroldoğan & Kumlu 2002; ...
Aquaculture Research, 2008
... Díaz-Herrera F., Sierra-Uribe E., Buckle-Ramírez LF &amp; Garrido-Mora A. (1998) Crit... more ... Díaz-Herrera F., Sierra-Uribe E., Buckle-Ramírez LF &amp; Garrido-Mora A. (1998) Critical thermal maxima and minima of Macrobrachium ... CrossRef. Manush SM, Pal AK, Chatterje N., Das T. &amp; Mukherjee SC (2004) Thermal tolerance and oxygen consumption of Macrobrachium ...
Aquaculture, 2004
In addition to modulating the function and stability of cellular mRNAs, microRNAs can profoundly ... more In addition to modulating the function and stability of cellular mRNAs, microRNAs can profoundly affect the life cycles of viruses bearing sequence complementary targets, a finding recently exploited to ameliorate toxicities of vaccines and oncolytic viruses. To elucidate the mechanisms underlying microRNA-mediated antiviral activity, we modified the 39 untranslated region (39UTR) of Coxsackievirus A21 to incorporate targets with varying degrees of homology to endogenous microRNAs. We show that microRNAs can interrupt the picornavirus life-cycle at multiple levels, including catalytic degradation of the viral RNA genome, suppression of cap-independent mRNA translation, and interference with genome encapsidation. In addition, we have examined the extent to which endogenous microRNAs can suppress viral replication in vivo and how viruses can overcome this inhibition by microRNA saturation in mouse cancer models.
Turkish Journal of Fisheries and Aquatic Sciences
Growth performance of Penaeus semisulcatus under semi-intensive and intensive systems in pond/tan... more Growth performance of Penaeus semisulcatus under semi-intensive and intensive systems in pond/tank culture conditions with pre-seasonally or over-wintered animals was studied in sub-tropical climate conditions of Turkey. In Pond A, the pre-seasonally produced post-larvae (PL) grew linearly from 0.2 g to 22.6 g in 140 days (Y = 0.19 X- 2.69; R2 = 0.97) with DGR (daily growth rate) of 0.06 g day-1. In Pond B, the over-wintered juveniles grew from 3.8 g to 30.5 g with DGR of 0.41 g during the first 30 days (weight gain of 14.42 g) and 0.13 g between 30 and 140 days (weight gain of 14.32 g). Regression equation for growth was calculated to be Y = 9.62 Log (X) + 4.51 (R2 = 0.99). Compensatory growth due to starvation or over-winter fasting has, for the first time, been demonstrated in this penaeid shrimp species in the present study. Food deprivation during the winter months resulted in growth compensation after refeeding under appropriate culture conditions. During the compensatory grow...
Mathematical Sciences Letters, 2014
Journal of Thermal Biology, 2021
Journal of Thermal Biology
Journal of Thermal Biology
Journal of the World Aquaculture Society, 2006
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 2004
The effects of neuropeptide Y (NPY) administered intramuscularly or orally on postlarvae (PLs) of... more The effects of neuropeptide Y (NPY) administered intramuscularly or orally on postlarvae (PLs) of two penaeid species were investigated in this study. In experiment 1, food intake (FI) of Marsupenaeus japonicus PLs (0.96 g), injected with NPY at 0.6 Ag per g BW, was investigated within 48 h posttreatment. In experiment 2, oral administration of NPY (at doses of 0, 0.125, 0.25, 0.5 Ag g À1 food) on feed intake and growth performance of Penaeus semisulcatus PLs (0.27 g) was examined for 6 weeks. In experiment 1, NPY injection significantly increased average daily FI of M. japonicus PLs within the first 24 h compared to the control (Pb0.05), but its stimulatory effect decreased on the second day (PN0.05). The increase in FI was 33% during the first 24 h and 17% during the next 24 h. In experiment 2, significant (Pb0.05) differences were found among the groups in terms of weight gain and food utilization (Pb0.05). Mean FI significantly increased (as much as 1.3-fold over the control) when NPY was orally administered at doses from 0.125 to 0.5 Ag g À1 feed. There was a positive relationship between FI and final weight (y=À0.972+2.098x, R 2 =0.81) and between FCE and NPY doses in the diets (y=45.37+3.46x, R 2 =0.91). The present findings indicated for the first time that NPY is a potent stimulator of food intake when administered either intramuscularly or orally to penaeid shrimps.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2004
The effects of neuropeptide Y (NPY) administered intramuscularly or orally on postlarvae (PLs) of... more The effects of neuropeptide Y (NPY) administered intramuscularly or orally on postlarvae (PLs) of two penaeid species were investigated in this study. In experiment 1, food intake (FI) of Marsupenaeus japonicus PLs (0.96 g), injected with NPY at 0.6 microg per g BW, was investigated within 48 h posttreatment. In experiment 2, oral administration of NPY (at doses of 0, 0.125, 0.25, 0.5 microg g(-1) food) on feed intake and growth performance of Penaeus semisulcatus PLs (0.27 g) was examined for 6 weeks. In experiment 1, NPY injection significantly increased average daily FI of M. japonicus PLs within the first 24 h compared to the control (P<0.05), but its stimulatory effect decreased on the second day (P>0.05). The increase in FI was 33% during the first 24 h and 17% during the next 24 h. In experiment 2, significant (P<0.05) differences were found among the groups in terms of weight gain and food utilization (P<0.05). Mean FI significantly increased (as much as 1.3-fold...
Journal of Comparative Physiology B
Süleyman Demirel Üniversitesi Eğirdir Su Ürünleri Fakültesi dergisi, Jan 4, 2006
Bu çalışmada, üç farklı büyüklükte (1, 5 ve 10 g) gökkuşağı alabalığı (Oncorhynchus mykiss) yavru... more Bu çalışmada, üç farklı büyüklükte (1, 5 ve 10 g) gökkuşağı alabalığı (Oncorhynchus mykiss) yavrularının, 13°C su sıcaklığında ve pH 7.0 seviyesinde, amonyak LC 50 değerleri tespit edilmiştir. Ayrıca balık büyüklüğü ile türün 24, 48, 72 ve 96 saatlik amonyak LC 50 değerleri arasındaki ilişki belirlenmiştir. Toplam Amonyak Nitrojeni (TAN) için 96 saatlik LC 50 değerleri 1, 5 ve 10 g balık yavrularında, sırasıyla 10.57 mg/L, 3.39 mg/L ve 2.50 mg/L olarak tespit edilmiştir. Her ağırlık grubu için, güvenli üst TAN seviyesi sırasıyla 1.05 mg/L, 0.33 mg/L ve 0.25 mg/L olarak hesaplanmıştır. Çalışma sonuçları balık ağırlığının artmasıyla amonyak LC 50 değerinin azaldığını göstermiştir.
Journal of Thermal Biology
TEZ5014Tez (Doktora) -- Çukurova Üniversitesi, Adana, 2004.Kaynakça (s. 89-102) var.ix, 101 s. ; ... more TEZ5014Tez (Doktora) -- Çukurova Üniversitesi, Adana, 2004.Kaynakça (s. 89-102) var.ix, 101 s. ; 30 cm.
Journal of the World Aquaculture Society, 2017
Sea bream, Sparus aurata, is one of the most important fish species that is commonly cultured in ... more Sea bream, Sparus aurata, is one of the most important fish species that is commonly cultured in the Mediterranean and the eastern coasts of the Atlantic Ocean. The life cycle of sea bream in its natural habitat passes through hyposaline and hypersaline lagoons. It is important to determine the tolerance of the fish to nitrogenous compounds for aquaculture at maximum stocking densities. In the present study, a series of acute experiments were performed to evaluate the effect of salinity on ammonia and nitrite toxicity to sea bream. The fish were exposed to different ammonia and nitrite concentrations according to the static renewal methodology at three different salinities (10, 20, and 30 ppt) and at a temperature of 20 C and a pH of 8.2. The toxic effect of total ammonia nitrogen (TAN) and nitrite nitrogen (NO 2-N) decreased with increasing salinity levels (P < 0.001). Acute toxicity (96-h lethal concentration 50 [LC 50 ]) values of TAN were determined to be 5.93, 11.72, and 19.38 mg/L at 10, 20, and 30 ppt salinity, respectively. The 96-h LC 50 values of NO 2-N were determined to be 370.80, 619.47, and 806.33 mg/L at 10, 20, and 30 ppt salinity, respectively. Results indicate that sea bream is less tolerant to ammonia but more tolerant to nitrite compared with some other fish species.
Journal of the World Aquaculture Society, 2015
Meagre, Argyrosomus regius, is a candidate marine fish species for aquaculture diversification, p... more Meagre, Argyrosomus regius, is a candidate marine fish species for aquaculture diversification, presenting a high economic value in the Mediterranean. Tolerance of juvenile meagre to nitrite (NO 2-N) was determined relating to temperature. Fish (3.2 ± 0.6 g and 5.4 ± 0.9 cm) were exposed to different NO 2-N concentrations in a series of acute toxicity tests by the static renewal method at three temperatures (18, 22, and 26 C) at a pH of 8.0. Low temperature clearly increased tolerance to NO 2-N (P < 0.05). The 96-h median lethal concentration (LC 50) values of NO 2-N were 177.63, 139.55, and 49.61 mg/L, at 18, 22, and 26 C, respectively. The safe levels of NO 2-N for juvenile meagre were estimated to be 17.7, 13.9, and 4.9 mg/L at 18, 22, and 26 C, respectively (P < 0.05). This study indicates A. regius is more sensitive to nitrite than other marine fish species cultured in the Mediterranean.
Aquaculture Research, 2015
Argyrosomus regius (3.0 ± 0.9 g) were exposed to different concentrations of ammonia in a series ... more Argyrosomus regius (3.0 ± 0.9 g) were exposed to different concentrations of ammonia in a series of acute toxicity tests by the static renewal method at three temperature levels (18, 22 and 26°C) at a pH of 8.2. Low temperature clearly increased the tolerance of the fish to total ammonia nitrogen (TAN) and unionized ammonia (NH3) (P < 0.05). While the 96-h LC50 values of TAN were 19.79, 10.39 and 5.06 mg L−1, the 96-h LC50 of NH3 were 1.00, 0.70 and 0.44 mg L−1 at 18, 22 and 26°C respectively. The safe levels of NH3 for A. regius was estimated to be 0.10, 0.07 and 0.04 mg L−1 at 18, 22 and 26°C respectively (P < 0.05). This study clearly indicates that A. regius is more sensitive to ammonia than other marine fish species cultured on the Mediterranean and Eastern Atlantic coasts.
Aquaculture Research, 2005
The European sea bass (Dicentrarchus labrax L.) is an economically important euryhaline marine fi... more The European sea bass (Dicentrarchus labrax L.) is an economically important euryhaline marine fish that frequently inhabits coastal waters of the Mediterranean Sea and is capable of tolerating both hypersaline and freshwater (FW) environments (Eroldoğan & Kumlu 2002; ...
Aquaculture Research, 2008
... Díaz-Herrera F., Sierra-Uribe E., Buckle-Ramírez LF &amp; Garrido-Mora A. (1998) Crit... more ... Díaz-Herrera F., Sierra-Uribe E., Buckle-Ramírez LF &amp; Garrido-Mora A. (1998) Critical thermal maxima and minima of Macrobrachium ... CrossRef. Manush SM, Pal AK, Chatterje N., Das T. &amp; Mukherjee SC (2004) Thermal tolerance and oxygen consumption of Macrobrachium ...
Aquaculture, 2004
In addition to modulating the function and stability of cellular mRNAs, microRNAs can profoundly ... more In addition to modulating the function and stability of cellular mRNAs, microRNAs can profoundly affect the life cycles of viruses bearing sequence complementary targets, a finding recently exploited to ameliorate toxicities of vaccines and oncolytic viruses. To elucidate the mechanisms underlying microRNA-mediated antiviral activity, we modified the 39 untranslated region (39UTR) of Coxsackievirus A21 to incorporate targets with varying degrees of homology to endogenous microRNAs. We show that microRNAs can interrupt the picornavirus life-cycle at multiple levels, including catalytic degradation of the viral RNA genome, suppression of cap-independent mRNA translation, and interference with genome encapsidation. In addition, we have examined the extent to which endogenous microRNAs can suppress viral replication in vivo and how viruses can overcome this inhibition by microRNA saturation in mouse cancer models.
Turkish Journal of Fisheries and Aquatic Sciences
Growth performance of Penaeus semisulcatus under semi-intensive and intensive systems in pond/tan... more Growth performance of Penaeus semisulcatus under semi-intensive and intensive systems in pond/tank culture conditions with pre-seasonally or over-wintered animals was studied in sub-tropical climate conditions of Turkey. In Pond A, the pre-seasonally produced post-larvae (PL) grew linearly from 0.2 g to 22.6 g in 140 days (Y = 0.19 X- 2.69; R2 = 0.97) with DGR (daily growth rate) of 0.06 g day-1. In Pond B, the over-wintered juveniles grew from 3.8 g to 30.5 g with DGR of 0.41 g during the first 30 days (weight gain of 14.42 g) and 0.13 g between 30 and 140 days (weight gain of 14.32 g). Regression equation for growth was calculated to be Y = 9.62 Log (X) + 4.51 (R2 = 0.99). Compensatory growth due to starvation or over-winter fasting has, for the first time, been demonstrated in this penaeid shrimp species in the present study. Food deprivation during the winter months resulted in growth compensation after refeeding under appropriate culture conditions. During the compensatory grow...
Mathematical Sciences Letters, 2014
Journal of Thermal Biology, 2021
Journal of Thermal Biology
Journal of Thermal Biology
Journal of the World Aquaculture Society, 2006
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 2004
The effects of neuropeptide Y (NPY) administered intramuscularly or orally on postlarvae (PLs) of... more The effects of neuropeptide Y (NPY) administered intramuscularly or orally on postlarvae (PLs) of two penaeid species were investigated in this study. In experiment 1, food intake (FI) of Marsupenaeus japonicus PLs (0.96 g), injected with NPY at 0.6 Ag per g BW, was investigated within 48 h posttreatment. In experiment 2, oral administration of NPY (at doses of 0, 0.125, 0.25, 0.5 Ag g À1 food) on feed intake and growth performance of Penaeus semisulcatus PLs (0.27 g) was examined for 6 weeks. In experiment 1, NPY injection significantly increased average daily FI of M. japonicus PLs within the first 24 h compared to the control (Pb0.05), but its stimulatory effect decreased on the second day (PN0.05). The increase in FI was 33% during the first 24 h and 17% during the next 24 h. In experiment 2, significant (Pb0.05) differences were found among the groups in terms of weight gain and food utilization (Pb0.05). Mean FI significantly increased (as much as 1.3-fold over the control) when NPY was orally administered at doses from 0.125 to 0.5 Ag g À1 feed. There was a positive relationship between FI and final weight (y=À0.972+2.098x, R 2 =0.81) and between FCE and NPY doses in the diets (y=45.37+3.46x, R 2 =0.91). The present findings indicated for the first time that NPY is a potent stimulator of food intake when administered either intramuscularly or orally to penaeid shrimps.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2004
The effects of neuropeptide Y (NPY) administered intramuscularly or orally on postlarvae (PLs) of... more The effects of neuropeptide Y (NPY) administered intramuscularly or orally on postlarvae (PLs) of two penaeid species were investigated in this study. In experiment 1, food intake (FI) of Marsupenaeus japonicus PLs (0.96 g), injected with NPY at 0.6 microg per g BW, was investigated within 48 h posttreatment. In experiment 2, oral administration of NPY (at doses of 0, 0.125, 0.25, 0.5 microg g(-1) food) on feed intake and growth performance of Penaeus semisulcatus PLs (0.27 g) was examined for 6 weeks. In experiment 1, NPY injection significantly increased average daily FI of M. japonicus PLs within the first 24 h compared to the control (P<0.05), but its stimulatory effect decreased on the second day (P>0.05). The increase in FI was 33% during the first 24 h and 17% during the next 24 h. In experiment 2, significant (P<0.05) differences were found among the groups in terms of weight gain and food utilization (P<0.05). Mean FI significantly increased (as much as 1.3-fold...