Mehmet Türk - Academia.edu (original) (raw)

Papers by Mehmet Türk

Bosnian Journal of Basic Medical Sciences

Fluoropyrimidine+cisplatin/oxaliplatin+trastuzumab therapy is recommended for the first-line trea... more Fluoropyrimidine+cisplatin/oxaliplatin+trastuzumab therapy is recommended for the first-line treatment of HER2-positive metastatic gastric adenocarcinoma. However, there is no comprehensive study on which platinum-based treatment should be preferred. This study aimed to compare the treatment response and survival characteristics of patients with HER2-positive metastatic gastric or gastroesophageal junction (GEJ) cancer who received fluorouracil, oxaliplatin, and leucovorin (mFOLFOX)+trastuzumab or cisplatin and fluorouracil (CF)+trastuzumab as first-line therapy. It was a multicenter, retrospective study of the Turkish Oncology Group, which included 243 patients from 21 oncology centers. There were 113 patients in the mFOLFOX+trastuzumab arm and 130 patients in the CF+trastuzumab arm. The median age was 62 years in the mFOLFOX+trastuzumab arm and 61 years in the CF+trastuzumab arm (P = 0.495). 81.4% of patients in the mFOLFOX+trastuzumab arm and 83.1% in the CF+trastuzumab arm had g...

World Owl Conference 2017, (26 - 30 Eylül 2017), Sep 30, 2017

In 2017, we began conducting migration and demographic work on the Scops Owl Otus scops in Turkey... more In 2017, we began conducting migration and demographic work on the Scops Owl Otus scops in Turkey. This methods paper is focused on three practical aspects of conducting Scops Owl research using nest boxes and related equipment. Based on the literature and input from other researchers, we developed and built nest boxes, a device (owl stopper) to capture owls by keeping them from exiting the nest boxes upon our approach, and a patio trap for capturing male owls. We offer specific plans with dimensions, material lists, and construction instructions and techniques to enable researchers to build and use these items for research on these small forest owls

Uluslararası Medeniyet Çalışmaları Dergisi, May 19, 2021

21. yüzyıl dünyasında, insanlar interneti çok boyutlu olarak hayatlarının birçok alanında kullanm... more 21. yüzyıl dünyasında, insanlar interneti çok boyutlu olarak hayatlarının birçok alanında kullanmakta ve dijital teknolojilerden yararlanmaktadır. Bu çalışmada, internet ve sosyal medya kullanımının, bireylerin hayatında gözetim olgusu çerçevesinde değerlendirilmesi ve insanların maruz kaldıkları gözetim asemblajının farkındalık düzeylerini ölçmek amaçlanmıştır. Çalışma kapsamında, nicel araştırma yöntemlerinden anket tekniğiyle kullanıcıların gözetim pratikleri hakkında farkındalık düzeyleri araştırılmıştır. Bu araştırmada, kullanıcıların veri toplanması ve gözetlenme konularında bilinç düzeylerinin yüksek olduğu, sosyal medyada paylaşım yaparken oluşturdukları içeriklerini bu gözetim unsuruna göre belirleyip paylaştıkları sonucuna ulaşılmıştır. Yapılan bu çalışmada Türkiye’de yaşayan bireylerin, dijital mecralarda maruz kaldıkları gözetim unsuru hakkında farkındalık düzeylerinin yüksek olduğu tespit edilmiştir.

Pediatric Nephrology, 2021

In the magnetic resonance evaluation of the abdomen, dilatation in the intrahepatic biliary tract... more In the magnetic resonance evaluation of the abdomen, dilatation in the intrahepatic biliary tract, which is thought to be secondary to external compression, dilatation compatible with grade 2 hydroureteronephrosis in both kidneys, constriction secondary to external pressure or tumoral infiltration at the level of the ureter pelvis, a luminal mass lesion that holds the lumen in a 10-cm segment proximal to the rectum, and invasion of the mass lesion into the bladder posterior wall and distal segment of both ureters (Fig. 1). Sigmoidoscopy and rectal endosonography revealed a malignant tumor occupying the lumen of the distal sigmoid colon and peritonitis carcinomatosa (Fig. 2).

Future Oncology, 2021

Aim: To assess the anxiety levels of breast cancer patients during the COVID-19 pandemic. Materia... more Aim: To assess the anxiety levels of breast cancer patients during the COVID-19 pandemic. Materials & methods: A total of 298 patients completed the State-Trait Anxiety Inventory (STAI-S and STAI-T) and the Visual Analogue Scale for Anxiety (VAS) and VAS for Anxiety in COVID-19 (VAS-CoV). Results: 144 patients were in the high anxiety category for STAI-S, and 202 patients were in the high anxiety category for STAI-T. STAI-T score was significantly high in the metastatic group (p = 0.017). VAS-CoV score in the hormonotherapy group was significantly higher than in the no-treatment group (p = 0.023). There was a positive correlation between VAS-CoV and VAS levels (r = 0.708, p < 0.001), VAS-CoV and STAI-S and STAI-T scores (r = 0.402, p < 0.001; r = 0.185, p = 0.001, respectively), and a negative correlation between education years and STAI-T scores (r = -0.172, p = 0.003). Conclusion: The COVID-19 pandemic is related to high anxiety levels in breast cancer patients.

Dicle Tıp Dergisi, 2022

Objective: The World Health Organization labelled the COVID-19 outbreak a pandemic on March 11, 2... more Objective: The World Health Organization labelled the COVID-19 outbreak a pandemic on March 11, 2020, the first day COVID-19 cases were diagnosed in Turkey. Since then, people's main concerns have been whether their lives or the lives of their relatives would be at risk if they became infected. The objective of this study was to determine the risk factors that increase mortality in COVID-19 patients treated in ICUs and to facilitate the appropriate precautions. Methods: In this study, patients who were diagnosed with COVID-19 [positive on a polymerase chain reaction (PCR) test] and monitored in the Pandemic Hospital at Diyarbakır Dicle University between 15 March 15 and 15 May, 2020, were evaluated for risk factors for mortality. Results: A total of 50 ICU patients were included in the study. Of them, 52% were males, and the mean age was 63.8±17.6 years. A comparison of deceased and surviving patients showed that being female, older than 62, and a smoker and having diabetes mellitus, hypertension, and/or coronary artery disease significantly increased mortality. An investigation of the findings from the patients' lung tomography examinations revealed that relatively prominent pulmonary involvement and localization did not affect mortality. Conclusions: Because patients who are advanced in age, female and smokers and have comorbidities are in the high-risk group, measurements related to treating the COVID-19 disease should be improved. Laboratory parameters are useful for the evaluation of mortality and morbidity, while mechanical ventilation increased mortality.

The Journal of International Civilization Studies, 2018

The major purpose of this study is to find out the extent of the influence of first language (Tur... more The major purpose of this study is to find out the extent of the influence of first language (Turkish) in use of possessives in second language (L2, English) and whether it is possible to overcome the first language (L1, Turkish) transfer effects in use of possessives through explicit instruction. The participants were 44 students at the beginner level of proficiency being enrolled in a language preparatory program at two private universities in Turkey. To enhance the credibility of the research, data were collected from three different types of sources namely; a translation activity, a multiple-choice activity and a picture description activity. The findings revealed that Turkish, as a mother tongue, had both positive and negative effect on learning English possessive structures both due to the similarities and differences between the two languages.

Dicle Tıp Dergisi, 2021

Covid-19 pandemisi sırasında acil servisler hastane ve yerel bakımın ön saflarında yer almaktadır... more Covid-19 pandemisi sırasında acil servisler hastane ve yerel bakımın ön saflarında yer almaktadır. Hem şüpheli COVID-19 vakalarını belirlemek ve yönetmek hem de diğer tıbbi acil durumları teşhis etmeye ve tedavi etmeye devam etmek için kritik öneme sahiptirler. Sonuç olarak, değişen ihtiyaçları karşılamak için acil servislerin yeniden gözden geçirilmesi gerekmektedir. Bu makalemizde COVID-19 pandemisi sırasında acil servis organizasyonu ve hasta yönetimi süreçlerine odaklanmayı amaçladık.

Future Oncology, 2021

Aim: To evaluate the efficacy of trastuzumab and potential risk factors on survival in patients w... more Aim: To evaluate the efficacy of trastuzumab and potential risk factors on survival in patients with HER2-positive metastatic gastric cancer. Methods: We retrospectively included 138 patients who were given trastuzumab-based chemotherapy as first-line treatment and analyzed the relationship between clinical response rates and maintenance treatment status and survival outcomes. Results: In the whole group, the median progression-free survival and overall survival were 10.2 and 16 months, respectively. Clinical response was obtained in 79% of patients. The median overall survival was 16.9 months in follow-up group and 19.0 months in the maintenance group in patients with clinical response. Continuation of maintenance trastuzumab created a significant survival advantage (p = 0.021). Eastern Cooperative Oncology Group performance status 2 (hazard ratio [HR]: 2.02), grade 3 (HR: 1.78) and more than four metastatic lesions (HR: 1.67) were determined as risk factors for death. Conclusion: ...

3. SEKTÖR SOSYAL EKONOMİ DERGİSİ, 2020

One of the main objectives of economics is the phenomenon of economic growth. Inflation, on the o... more One of the main objectives of economics is the phenomenon of economic growth. Inflation, on the other hand, is a factor that has a determining effect on the basic macroeconomic variables of the economy. In this study were examined the relationship between inflation and growth in Turkey for the period 2003:1- 2019:4. Empirical findings showed the suppressive effect of inflation on growth in the period analyzed. It has been demonstrated that the 1% inflation increase reduced growth by about 0.54%. In the study, Engel Granger Cointegration Analysis based on error correction model (ECT) was performed for long term relationship between variables. As a result of the analysis, the existence of a long-term relationship has been proved.

Current Problems in Cancer, 2020

Objective: The essential treatment for patients with renal cell carcinoma is nephrectomy. As no l... more Objective: The essential treatment for patients with renal cell carcinoma is nephrectomy. As no lymph node dissection (LND) could be performed in the majority of these patients, healthy staging could not be carried out. In this study, we investigated the impact of LND during nephrectomy on patient survival. Methods: A total of 181 patients-58 (32%) were female and 123 (68%) were male-were included in the study. Median follow-up period was 48 months. The patients were separated into 4 groups according to their stage during diagnosis; group 1 (T1-3N0M0), group 2 (T1-3NXM0), group 3 (T1-3N1M0), and group 4 (T1-4N0/XM1). The disease-free survival of nonmetastatic patients and the overall survival of all groups were calculated. Results: Mean age was 58.4 ± 12.0 years. Median survival for Group 1 could not be reached. Median survival was 89 months in Group 2, 50 months in Group 3, and 39 months in Group 4 (P < 0.001). There was no statistically significant difference between the N1 and M1 groups (P = 0.297). For the NX patient group without LND, median survival was 89 months, which is worse than the N0 group and better than the N1 group (P = 0.002). Conclusions: Our study presumes that the patients without LND are not staged sufficiently, NX patients have worse survival rates when compared with N0 patients, node

European Journal of Radiology, 2020

This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Marmara Üniversitesi Hukuk Fakültesi Hukuk Araştırmaları Dergisi, 2019

Ülkemizde finansmana erişimin kolaylaştırılması amacıyla kabul edilen 20.10.2016 tarih ve 6750 sa... more Ülkemizde finansmana erişimin kolaylaştırılması amacıyla kabul edilen 20.10.2016 tarih ve 6750 sayılı Ticari İşlemlerde Taşınır Rehni Kanunu, 01.01.2017 tarihinde yürürlüğe girmiştir. Kanunda yeni bir teslimsiz ve sicilli taşınır rehin türü düzenlenmiştir. Kanun, yakından incelendiğinde, rehnin kuruluşu, hükümleri ve sonuçları bakımından farklı düzenlemelere yer verildiği görülmektedir. Yine, borçlunun temerrüdü durumunda genel hükümler çerçevesinde takip yapmak dışında, alacaklıya tanınan seçimlik haklar dikkat çekicidir. Bu hakların en başında, rehinli taşınırın mülkiyetinin devrini talep etme hakkı gelmektedir. Kanun, kullanılan dil açısından da mevcut düzenlemelerden farklılıklar içermektedir. Bu Kanunda, 4721 sayılı Türk Medeni Kanunu ve 6102 sayılı Türk Ticaret Kanunu gibi temel kanunlarda bilinçli bir şekilde yer verilmeyen bazı kavramlar kullanılmıştır. Bütün bunlarla birlikte, Ticari İşlemlerde Taşınır Rehni Kanunu, yürürlüğe girmesinin üstünden iki buçuk yıl geçmesine rağmen hâlâ tartışılmaktadır. Tartışmalı konuların en başında, Kanunun isminde de yer alan "ticari işlem" ifadesinden ne anlaşılması gerektiği ve bunun Kanunun uygulama alanının tespitinde bir ölçüt olup olmadığı hususu gelmektedir. Rehin hukukunda kabul edilen temel ilkelerden uzaklaşılması da diğer bir önemli tartışma konusudur. Yapılan tartışmaların bazılarına ise, Kanun ile ilgili yapılan ikincil mevzuat düzenlemeleri yol açmaktadır. Kanunun uygulanmasını sağlamak üzere çıkarılan ikincil mevzuatta yer alan bazı düzenlemeler Kanuna açıkça aykırıdır. Bu çalışmada, Ticari İşlemlerde Taşınır Rehni Kanunu ile ilgili mevzuat hükümleri Medeni Hukuk ve Ticaret Hukuku bakımından incelenmiştir.

Annals of Oncology, 2019

Background Fear of cancer recurrence (FCR) is an important psychological trauma that has been ass... more Background Fear of cancer recurrence (FCR) is an important psychological trauma that has been associated with reduction in the quality of life, disruptions in the level of adjustment, emotional distress and anxiety. The purpose of the study is to evaluate the impact of patient–physician relationship on FCR. Methods The study was designed as a multicenter survey study. The cancer survivors who were under remission, were evaluated with structured questionnaires. Patient–physician relationship (PPR) scale in which higher scores indicate better relationship and FCR inventory were used. Results Between January-April 2019, 1580 patients were evaluated. The median age was 57.0(19-88) and 66% were female. There was high level of FCR scores in 51% of participants. There was a negative correlation between PPR and FCR scores (r= -0.134, p

Harran Üniversitesi Tıp Fakültesi Dergisi, 2019

Kanser dünyada çok yaygın ölümcül bir hastalıktır. Kanser oluşumunda birçok nedenden dolayı hücre... more Kanser dünyada çok yaygın ölümcül bir hastalıktır. Kanser oluşumunda birçok nedenden dolayı hücresel düzeyde meydana gelen oksidatif stresin etkili olduğu düşünülmektedir. Bu çalışmada akciğer, meme ve kolon kanserlerinde oksidatif durumun kanser türlerindeki değişiminin araştırılması amaçlandı. Materyal ve Metot: Medikal Onkoloji bölümünde tedavileri süren 44 akciğer kanseri, 37 meme kanseri, 20 kolon kanseri hastası çalışmaya dahil edildi. Çalışmaya katılan hastaların tamamı histopatolojik olarak tanısı kesinleştirilirmiş hastalardı. Hastaların Total Antioksidan Seviye (TAS), Total Oksidan Seviye (TOS) ile Katalaz (CAT) ve Myeloperoksidaz (MPO) enzim aktiviteleri otoanalizörde fotometrik yöntemle ölçülüp, 43 sağlıklı gönüllü ile karşılaştırıldı. Bulgular: TOS seviyeleri kontrol grubuna göre meme kanserinde anlamlı olarak yüksek bulunurken (p<0.002), diğer kanser gruplarında yüksek olmakla birlikte anlamlı fark bulunmadı. Oksidatif Stres İndeksi (OSİ) ise her üç kanser türünde de kontrol grubuna göre anlamlı derecede düşük bulundu (p<0.001). TAS, CAT ve MPO aktiviteleri her üç kanser tipinde de kontrol grubuna göre anlamlı derecede yüksek idi. (p<0.001). Sonuç: Çalışmada, kanserde oksidatif stresin arttığı ancak, artmış oksidatif stresin antioksidan savunma sistemini indüklemesi nedeni ile OSI seviyesini düşürmüş olabileceği sonucuna varıldı.

Journal of Turkish Studies, 2018

The Journal of International Civilization Studies, 2018

Turkiye Klinikleri Journal of Case Reports, 2016

Alisveris merkezleri, kurulmaya basladiklari ilk gunden bu yana hizli bir gelisme surecine girmis... more Alisveris merkezleri, kurulmaya basladiklari ilk gunden bu yana hizli bir gelisme surecine girmis, kentsel alan gelisiminde ve tuketicinin gunluk hayatinda her gecen gun daha da onemli hale gelmistir. Literaturde alisveris merkezlerinin bir yandan daha fazla yatirim ile beraber ekonomiye ciddi fayda sagladiklarindan bahsedilmekte, diger taraftan kent merkezlerini bosalttiklari ve gereksizlestirdikleri gerekcesiyle sik sik elestirilmektedirler. Bu calismada, gunumuze kadar gelistirilen ve gelistirilmekte olan alisveris merkezi projelerinin incelenmesi ve bu merkezlerin fiziksel, ekonomik ozelliklerinin disinda kurulus yerlerinin (lokasyon ozelliklerinin) detayli olarak analiz edilmesi hedeflenmistir. Buyuk butceler ile kurulan bu projelerin mekansal olarak degerlendirilmesi ve yer secimi kriterlerinin projenin basarisi uzerindeki etkileri uzerinde durulmustur. Bu cercevede, calismanin ilk bolumunde arastirmanin temel konusu olan alisveris merkezlerinin alisveris merkezi kavrami, bu merkezlerin tarihsel gelisimi ve genel ozellikleri ile birlikte perakende sektorunde son yillardaki gelisim uzerinde durulmus ve elde edilen guncel veriler ile Turkiye’nin bu alanda Avrupa ulkeleri ile karsilastirmasi yapilarak sektordeki yeri ve gelisme firsatlari degerlendirilmistir. Calismanin ikinci bolumunde alisveris merkezlerinin lokasyon secimi kararlari uzerinde durulmus ve belirlenen yer secimi kriterlerinin gerek literatur arastirmasi yapilarak gerekse Turkiye’nin en fazla alisveris merkezi yatirimina sahip 3 ilindeki (Istanbul, Ankara, Izmir) merkezleri ornek alinarak degerlendirilmistir. Genel bilgilerin yaninda yapilan ziyaretci ve yatirimci/ yonetici soru formu calismalari ile yer secimi kriterlerinin yorumlanmasi uzerine cesitli bulgular elde edilmis ve yorumlanmistir. Calismanin sonuc bolumunde elde edilen veriler sonucunda alisveris merkezi yatirimi yapan yerli ve yabanci firmalara, kamu kurumlarina, bu merkezler icinde kiralama yapacak perakende kuruluslarina yararli ve yol gosterici bazi onerilerin ortaya koyulmasi amaclanmistir. Bu sayede henuz cok fazla calisilmamis bu alanda kendinden sonra yapilacak olan calismalara da yol gosterici bilgiler sunulmustur. Abstract Shopping centers are been in a fast development process since they have been first established. These centers take an important role both in urban land development and the consumers’ daily life. It is been sorted out in the academic literature that shopping centers have seriously beneficial impacts on economy as these projects require huge investment budgets. On the other hand, shopping centers have been critised in some studies that they are vacating and trivializing the traditional city centers. This academic thesis aims to analyse both the current shopping center development projects and site selection features besides the physical and economic features. It is been studied to mention the impacts of site selections criterias on the success of the development projets and to consider these highly expensive investment projects in a spatial view. Within this context, the shopping center concept and definiton, historical development of shopping centers and general features of shopping centers have been discussed in the first part of the thesis. Moreover, current progress in retail and property markets have been sorted out and Turkey’s potential and improvement opportunities have been mentioned in this part of the study. In the second part, site selection decisions of shopping center projects are studied. Defined site selection criterias are critised both by literature inquiries and by examples from 3 biggest cities of Turkey in terms of shopping center investments (Istanbul, Ankara and Izmir). Besides of the general assessments, comments about site selection criterias acquired by customer and investor/ manager questionnaires are included in the second part of the study. In the conclusion part, it is aimed to present beneficial recommendations to shopping center investors, public authorities and retail companies that will acquire retail units in shopping centers by evaluating data acquired in the second part. By the same token, some guiding data is supplied to academic studies as site selection subject is not a frequently studied area.

Bosnian Journal of Basic Medical Sciences

Fluoropyrimidine+cisplatin/oxaliplatin+trastuzumab therapy is recommended for the first-line trea... more Fluoropyrimidine+cisplatin/oxaliplatin+trastuzumab therapy is recommended for the first-line treatment of HER2-positive metastatic gastric adenocarcinoma. However, there is no comprehensive study on which platinum-based treatment should be preferred. This study aimed to compare the treatment response and survival characteristics of patients with HER2-positive metastatic gastric or gastroesophageal junction (GEJ) cancer who received fluorouracil, oxaliplatin, and leucovorin (mFOLFOX)+trastuzumab or cisplatin and fluorouracil (CF)+trastuzumab as first-line therapy. It was a multicenter, retrospective study of the Turkish Oncology Group, which included 243 patients from 21 oncology centers. There were 113 patients in the mFOLFOX+trastuzumab arm and 130 patients in the CF+trastuzumab arm. The median age was 62 years in the mFOLFOX+trastuzumab arm and 61 years in the CF+trastuzumab arm (P = 0.495). 81.4% of patients in the mFOLFOX+trastuzumab arm and 83.1% in the CF+trastuzumab arm had g...

World Owl Conference 2017, (26 - 30 Eylül 2017), Sep 30, 2017

In 2017, we began conducting migration and demographic work on the Scops Owl Otus scops in Turkey... more In 2017, we began conducting migration and demographic work on the Scops Owl Otus scops in Turkey. This methods paper is focused on three practical aspects of conducting Scops Owl research using nest boxes and related equipment. Based on the literature and input from other researchers, we developed and built nest boxes, a device (owl stopper) to capture owls by keeping them from exiting the nest boxes upon our approach, and a patio trap for capturing male owls. We offer specific plans with dimensions, material lists, and construction instructions and techniques to enable researchers to build and use these items for research on these small forest owls

Uluslararası Medeniyet Çalışmaları Dergisi, May 19, 2021

21. yüzyıl dünyasında, insanlar interneti çok boyutlu olarak hayatlarının birçok alanında kullanm... more 21. yüzyıl dünyasında, insanlar interneti çok boyutlu olarak hayatlarının birçok alanında kullanmakta ve dijital teknolojilerden yararlanmaktadır. Bu çalışmada, internet ve sosyal medya kullanımının, bireylerin hayatında gözetim olgusu çerçevesinde değerlendirilmesi ve insanların maruz kaldıkları gözetim asemblajının farkındalık düzeylerini ölçmek amaçlanmıştır. Çalışma kapsamında, nicel araştırma yöntemlerinden anket tekniğiyle kullanıcıların gözetim pratikleri hakkında farkındalık düzeyleri araştırılmıştır. Bu araştırmada, kullanıcıların veri toplanması ve gözetlenme konularında bilinç düzeylerinin yüksek olduğu, sosyal medyada paylaşım yaparken oluşturdukları içeriklerini bu gözetim unsuruna göre belirleyip paylaştıkları sonucuna ulaşılmıştır. Yapılan bu çalışmada Türkiye’de yaşayan bireylerin, dijital mecralarda maruz kaldıkları gözetim unsuru hakkında farkındalık düzeylerinin yüksek olduğu tespit edilmiştir.

Pediatric Nephrology, 2021

In the magnetic resonance evaluation of the abdomen, dilatation in the intrahepatic biliary tract... more In the magnetic resonance evaluation of the abdomen, dilatation in the intrahepatic biliary tract, which is thought to be secondary to external compression, dilatation compatible with grade 2 hydroureteronephrosis in both kidneys, constriction secondary to external pressure or tumoral infiltration at the level of the ureter pelvis, a luminal mass lesion that holds the lumen in a 10-cm segment proximal to the rectum, and invasion of the mass lesion into the bladder posterior wall and distal segment of both ureters (Fig. 1). Sigmoidoscopy and rectal endosonography revealed a malignant tumor occupying the lumen of the distal sigmoid colon and peritonitis carcinomatosa (Fig. 2).

Future Oncology, 2021

Aim: To assess the anxiety levels of breast cancer patients during the COVID-19 pandemic. Materia... more Aim: To assess the anxiety levels of breast cancer patients during the COVID-19 pandemic. Materials & methods: A total of 298 patients completed the State-Trait Anxiety Inventory (STAI-S and STAI-T) and the Visual Analogue Scale for Anxiety (VAS) and VAS for Anxiety in COVID-19 (VAS-CoV). Results: 144 patients were in the high anxiety category for STAI-S, and 202 patients were in the high anxiety category for STAI-T. STAI-T score was significantly high in the metastatic group (p = 0.017). VAS-CoV score in the hormonotherapy group was significantly higher than in the no-treatment group (p = 0.023). There was a positive correlation between VAS-CoV and VAS levels (r = 0.708, p < 0.001), VAS-CoV and STAI-S and STAI-T scores (r = 0.402, p < 0.001; r = 0.185, p = 0.001, respectively), and a negative correlation between education years and STAI-T scores (r = -0.172, p = 0.003). Conclusion: The COVID-19 pandemic is related to high anxiety levels in breast cancer patients.

Dicle Tıp Dergisi, 2022

Objective: The World Health Organization labelled the COVID-19 outbreak a pandemic on March 11, 2... more Objective: The World Health Organization labelled the COVID-19 outbreak a pandemic on March 11, 2020, the first day COVID-19 cases were diagnosed in Turkey. Since then, people's main concerns have been whether their lives or the lives of their relatives would be at risk if they became infected. The objective of this study was to determine the risk factors that increase mortality in COVID-19 patients treated in ICUs and to facilitate the appropriate precautions. Methods: In this study, patients who were diagnosed with COVID-19 [positive on a polymerase chain reaction (PCR) test] and monitored in the Pandemic Hospital at Diyarbakır Dicle University between 15 March 15 and 15 May, 2020, were evaluated for risk factors for mortality. Results: A total of 50 ICU patients were included in the study. Of them, 52% were males, and the mean age was 63.8±17.6 years. A comparison of deceased and surviving patients showed that being female, older than 62, and a smoker and having diabetes mellitus, hypertension, and/or coronary artery disease significantly increased mortality. An investigation of the findings from the patients' lung tomography examinations revealed that relatively prominent pulmonary involvement and localization did not affect mortality. Conclusions: Because patients who are advanced in age, female and smokers and have comorbidities are in the high-risk group, measurements related to treating the COVID-19 disease should be improved. Laboratory parameters are useful for the evaluation of mortality and morbidity, while mechanical ventilation increased mortality.

The Journal of International Civilization Studies, 2018

The major purpose of this study is to find out the extent of the influence of first language (Tur... more The major purpose of this study is to find out the extent of the influence of first language (Turkish) in use of possessives in second language (L2, English) and whether it is possible to overcome the first language (L1, Turkish) transfer effects in use of possessives through explicit instruction. The participants were 44 students at the beginner level of proficiency being enrolled in a language preparatory program at two private universities in Turkey. To enhance the credibility of the research, data were collected from three different types of sources namely; a translation activity, a multiple-choice activity and a picture description activity. The findings revealed that Turkish, as a mother tongue, had both positive and negative effect on learning English possessive structures both due to the similarities and differences between the two languages.

Dicle Tıp Dergisi, 2021

Covid-19 pandemisi sırasında acil servisler hastane ve yerel bakımın ön saflarında yer almaktadır... more Covid-19 pandemisi sırasında acil servisler hastane ve yerel bakımın ön saflarında yer almaktadır. Hem şüpheli COVID-19 vakalarını belirlemek ve yönetmek hem de diğer tıbbi acil durumları teşhis etmeye ve tedavi etmeye devam etmek için kritik öneme sahiptirler. Sonuç olarak, değişen ihtiyaçları karşılamak için acil servislerin yeniden gözden geçirilmesi gerekmektedir. Bu makalemizde COVID-19 pandemisi sırasında acil servis organizasyonu ve hasta yönetimi süreçlerine odaklanmayı amaçladık.

Future Oncology, 2021

Aim: To evaluate the efficacy of trastuzumab and potential risk factors on survival in patients w... more Aim: To evaluate the efficacy of trastuzumab and potential risk factors on survival in patients with HER2-positive metastatic gastric cancer. Methods: We retrospectively included 138 patients who were given trastuzumab-based chemotherapy as first-line treatment and analyzed the relationship between clinical response rates and maintenance treatment status and survival outcomes. Results: In the whole group, the median progression-free survival and overall survival were 10.2 and 16 months, respectively. Clinical response was obtained in 79% of patients. The median overall survival was 16.9 months in follow-up group and 19.0 months in the maintenance group in patients with clinical response. Continuation of maintenance trastuzumab created a significant survival advantage (p = 0.021). Eastern Cooperative Oncology Group performance status 2 (hazard ratio [HR]: 2.02), grade 3 (HR: 1.78) and more than four metastatic lesions (HR: 1.67) were determined as risk factors for death. Conclusion: ...

3. SEKTÖR SOSYAL EKONOMİ DERGİSİ, 2020

One of the main objectives of economics is the phenomenon of economic growth. Inflation, on the o... more One of the main objectives of economics is the phenomenon of economic growth. Inflation, on the other hand, is a factor that has a determining effect on the basic macroeconomic variables of the economy. In this study were examined the relationship between inflation and growth in Turkey for the period 2003:1- 2019:4. Empirical findings showed the suppressive effect of inflation on growth in the period analyzed. It has been demonstrated that the 1% inflation increase reduced growth by about 0.54%. In the study, Engel Granger Cointegration Analysis based on error correction model (ECT) was performed for long term relationship between variables. As a result of the analysis, the existence of a long-term relationship has been proved.

Current Problems in Cancer, 2020

Objective: The essential treatment for patients with renal cell carcinoma is nephrectomy. As no l... more Objective: The essential treatment for patients with renal cell carcinoma is nephrectomy. As no lymph node dissection (LND) could be performed in the majority of these patients, healthy staging could not be carried out. In this study, we investigated the impact of LND during nephrectomy on patient survival. Methods: A total of 181 patients-58 (32%) were female and 123 (68%) were male-were included in the study. Median follow-up period was 48 months. The patients were separated into 4 groups according to their stage during diagnosis; group 1 (T1-3N0M0), group 2 (T1-3NXM0), group 3 (T1-3N1M0), and group 4 (T1-4N0/XM1). The disease-free survival of nonmetastatic patients and the overall survival of all groups were calculated. Results: Mean age was 58.4 ± 12.0 years. Median survival for Group 1 could not be reached. Median survival was 89 months in Group 2, 50 months in Group 3, and 39 months in Group 4 (P < 0.001). There was no statistically significant difference between the N1 and M1 groups (P = 0.297). For the NX patient group without LND, median survival was 89 months, which is worse than the N0 group and better than the N1 group (P = 0.002). Conclusions: Our study presumes that the patients without LND are not staged sufficiently, NX patients have worse survival rates when compared with N0 patients, node

European Journal of Radiology, 2020

This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Marmara Üniversitesi Hukuk Fakültesi Hukuk Araştırmaları Dergisi, 2019

Ülkemizde finansmana erişimin kolaylaştırılması amacıyla kabul edilen 20.10.2016 tarih ve 6750 sa... more Ülkemizde finansmana erişimin kolaylaştırılması amacıyla kabul edilen 20.10.2016 tarih ve 6750 sayılı Ticari İşlemlerde Taşınır Rehni Kanunu, 01.01.2017 tarihinde yürürlüğe girmiştir. Kanunda yeni bir teslimsiz ve sicilli taşınır rehin türü düzenlenmiştir. Kanun, yakından incelendiğinde, rehnin kuruluşu, hükümleri ve sonuçları bakımından farklı düzenlemelere yer verildiği görülmektedir. Yine, borçlunun temerrüdü durumunda genel hükümler çerçevesinde takip yapmak dışında, alacaklıya tanınan seçimlik haklar dikkat çekicidir. Bu hakların en başında, rehinli taşınırın mülkiyetinin devrini talep etme hakkı gelmektedir. Kanun, kullanılan dil açısından da mevcut düzenlemelerden farklılıklar içermektedir. Bu Kanunda, 4721 sayılı Türk Medeni Kanunu ve 6102 sayılı Türk Ticaret Kanunu gibi temel kanunlarda bilinçli bir şekilde yer verilmeyen bazı kavramlar kullanılmıştır. Bütün bunlarla birlikte, Ticari İşlemlerde Taşınır Rehni Kanunu, yürürlüğe girmesinin üstünden iki buçuk yıl geçmesine rağmen hâlâ tartışılmaktadır. Tartışmalı konuların en başında, Kanunun isminde de yer alan "ticari işlem" ifadesinden ne anlaşılması gerektiği ve bunun Kanunun uygulama alanının tespitinde bir ölçüt olup olmadığı hususu gelmektedir. Rehin hukukunda kabul edilen temel ilkelerden uzaklaşılması da diğer bir önemli tartışma konusudur. Yapılan tartışmaların bazılarına ise, Kanun ile ilgili yapılan ikincil mevzuat düzenlemeleri yol açmaktadır. Kanunun uygulanmasını sağlamak üzere çıkarılan ikincil mevzuatta yer alan bazı düzenlemeler Kanuna açıkça aykırıdır. Bu çalışmada, Ticari İşlemlerde Taşınır Rehni Kanunu ile ilgili mevzuat hükümleri Medeni Hukuk ve Ticaret Hukuku bakımından incelenmiştir.

Annals of Oncology, 2019

Background Fear of cancer recurrence (FCR) is an important psychological trauma that has been ass... more Background Fear of cancer recurrence (FCR) is an important psychological trauma that has been associated with reduction in the quality of life, disruptions in the level of adjustment, emotional distress and anxiety. The purpose of the study is to evaluate the impact of patient–physician relationship on FCR. Methods The study was designed as a multicenter survey study. The cancer survivors who were under remission, were evaluated with structured questionnaires. Patient–physician relationship (PPR) scale in which higher scores indicate better relationship and FCR inventory were used. Results Between January-April 2019, 1580 patients were evaluated. The median age was 57.0(19-88) and 66% were female. There was high level of FCR scores in 51% of participants. There was a negative correlation between PPR and FCR scores (r= -0.134, p

Harran Üniversitesi Tıp Fakültesi Dergisi, 2019

Kanser dünyada çok yaygın ölümcül bir hastalıktır. Kanser oluşumunda birçok nedenden dolayı hücre... more Kanser dünyada çok yaygın ölümcül bir hastalıktır. Kanser oluşumunda birçok nedenden dolayı hücresel düzeyde meydana gelen oksidatif stresin etkili olduğu düşünülmektedir. Bu çalışmada akciğer, meme ve kolon kanserlerinde oksidatif durumun kanser türlerindeki değişiminin araştırılması amaçlandı. Materyal ve Metot: Medikal Onkoloji bölümünde tedavileri süren 44 akciğer kanseri, 37 meme kanseri, 20 kolon kanseri hastası çalışmaya dahil edildi. Çalışmaya katılan hastaların tamamı histopatolojik olarak tanısı kesinleştirilirmiş hastalardı. Hastaların Total Antioksidan Seviye (TAS), Total Oksidan Seviye (TOS) ile Katalaz (CAT) ve Myeloperoksidaz (MPO) enzim aktiviteleri otoanalizörde fotometrik yöntemle ölçülüp, 43 sağlıklı gönüllü ile karşılaştırıldı. Bulgular: TOS seviyeleri kontrol grubuna göre meme kanserinde anlamlı olarak yüksek bulunurken (p<0.002), diğer kanser gruplarında yüksek olmakla birlikte anlamlı fark bulunmadı. Oksidatif Stres İndeksi (OSİ) ise her üç kanser türünde de kontrol grubuna göre anlamlı derecede düşük bulundu (p<0.001). TAS, CAT ve MPO aktiviteleri her üç kanser tipinde de kontrol grubuna göre anlamlı derecede yüksek idi. (p<0.001). Sonuç: Çalışmada, kanserde oksidatif stresin arttığı ancak, artmış oksidatif stresin antioksidan savunma sistemini indüklemesi nedeni ile OSI seviyesini düşürmüş olabileceği sonucuna varıldı.

Journal of Turkish Studies, 2018

The Journal of International Civilization Studies, 2018

Turkiye Klinikleri Journal of Case Reports, 2016

Alisveris merkezleri, kurulmaya basladiklari ilk gunden bu yana hizli bir gelisme surecine girmis... more Alisveris merkezleri, kurulmaya basladiklari ilk gunden bu yana hizli bir gelisme surecine girmis, kentsel alan gelisiminde ve tuketicinin gunluk hayatinda her gecen gun daha da onemli hale gelmistir. Literaturde alisveris merkezlerinin bir yandan daha fazla yatirim ile beraber ekonomiye ciddi fayda sagladiklarindan bahsedilmekte, diger taraftan kent merkezlerini bosalttiklari ve gereksizlestirdikleri gerekcesiyle sik sik elestirilmektedirler. Bu calismada, gunumuze kadar gelistirilen ve gelistirilmekte olan alisveris merkezi projelerinin incelenmesi ve bu merkezlerin fiziksel, ekonomik ozelliklerinin disinda kurulus yerlerinin (lokasyon ozelliklerinin) detayli olarak analiz edilmesi hedeflenmistir. Buyuk butceler ile kurulan bu projelerin mekansal olarak degerlendirilmesi ve yer secimi kriterlerinin projenin basarisi uzerindeki etkileri uzerinde durulmustur. Bu cercevede, calismanin ilk bolumunde arastirmanin temel konusu olan alisveris merkezlerinin alisveris merkezi kavrami, bu merkezlerin tarihsel gelisimi ve genel ozellikleri ile birlikte perakende sektorunde son yillardaki gelisim uzerinde durulmus ve elde edilen guncel veriler ile Turkiye’nin bu alanda Avrupa ulkeleri ile karsilastirmasi yapilarak sektordeki yeri ve gelisme firsatlari degerlendirilmistir. Calismanin ikinci bolumunde alisveris merkezlerinin lokasyon secimi kararlari uzerinde durulmus ve belirlenen yer secimi kriterlerinin gerek literatur arastirmasi yapilarak gerekse Turkiye’nin en fazla alisveris merkezi yatirimina sahip 3 ilindeki (Istanbul, Ankara, Izmir) merkezleri ornek alinarak degerlendirilmistir. Genel bilgilerin yaninda yapilan ziyaretci ve yatirimci/ yonetici soru formu calismalari ile yer secimi kriterlerinin yorumlanmasi uzerine cesitli bulgular elde edilmis ve yorumlanmistir. Calismanin sonuc bolumunde elde edilen veriler sonucunda alisveris merkezi yatirimi yapan yerli ve yabanci firmalara, kamu kurumlarina, bu merkezler icinde kiralama yapacak perakende kuruluslarina yararli ve yol gosterici bazi onerilerin ortaya koyulmasi amaclanmistir. Bu sayede henuz cok fazla calisilmamis bu alanda kendinden sonra yapilacak olan calismalara da yol gosterici bilgiler sunulmustur. Abstract Shopping centers are been in a fast development process since they have been first established. These centers take an important role both in urban land development and the consumers’ daily life. It is been sorted out in the academic literature that shopping centers have seriously beneficial impacts on economy as these projects require huge investment budgets. On the other hand, shopping centers have been critised in some studies that they are vacating and trivializing the traditional city centers. This academic thesis aims to analyse both the current shopping center development projects and site selection features besides the physical and economic features. It is been studied to mention the impacts of site selections criterias on the success of the development projets and to consider these highly expensive investment projects in a spatial view. Within this context, the shopping center concept and definiton, historical development of shopping centers and general features of shopping centers have been discussed in the first part of the thesis. Moreover, current progress in retail and property markets have been sorted out and Turkey’s potential and improvement opportunities have been mentioned in this part of the study. In the second part, site selection decisions of shopping center projects are studied. Defined site selection criterias are critised both by literature inquiries and by examples from 3 biggest cities of Turkey in terms of shopping center investments (Istanbul, Ankara and Izmir). Besides of the general assessments, comments about site selection criterias acquired by customer and investor/ manager questionnaires are included in the second part of the study. In the conclusion part, it is aimed to present beneficial recommendations to shopping center investors, public authorities and retail companies that will acquire retail units in shopping centers by evaluating data acquired in the second part. By the same token, some guiding data is supplied to academic studies as site selection subject is not a frequently studied area.