Berenice Mendoza - Academia.edu (original) (raw)

Papers by Berenice Mendoza

Research paper thumbnail of From Genes to Flower Patterns and Evolution: Dynamic Models of Gene Regulatory Networks

Journal of Plant Growth Regulation, 2006

Genes and proteins form complex dynamical systems or gene regulatory networks (GRN) that can reac... more Genes and proteins form complex dynamical systems or gene regulatory networks (GRN) that can reach several steady states (attractors). These may be associated with distinct cell types. In plants, the ABC combinatorial model establishes the necessary gene combinations for floral organ cell specification. We have developed dynamic gene regulatory network (GRN) models to understand how the combinatorial selection of gene activity is established during floral organ primordia specification as a result of the concerted action of ABC and non-ABC genes. Our analyses have shown that the floral organ specification GRN reaches six attractors with gene configurations observed in primordial cell types during early stages of flower development and four that correspond to regions of the inflorescence meristem. This suggests that it is the overall GRN dynamics rather than precise signals that underlie the ABC model. Furthermore, our analyses suggest that the steady states of the GRN are robust to random alterations of the logical functions that define the gene interactions. Here we have updated the GRN model and have systematically altered the outputs of all the logical functions and addressed in which cases the original attractors are recovered. We then reduced the original three-state GRN to a two-state (Boolean) GRN and performed the same systematic perturbation analysis. Interestingly, the Boolean GRN reaches the same number and type of attractors as reached by the three-state GRN, and it responds to perturbations in a qualitatively identical manner as the original GRN. These results suggest that a Boolean model is sufficient to capture the dynamical features of the floral network and provide additional support for the robustness of the floral GRN. These findings further support that the GRN model provides a dynamical explanation for the ABC model and that the floral GRN robustness could be behind the widespread conservation of the floral plan among eudicotyledoneous plants. Other aspects of evolution of flower organ arrangement and ABC gene expression patterns are discussed in the context of the approach proposed here.

Research paper thumbnail of Multicolor Photometry of Stellar Aggregates

We have made multicolor photometric observations over the range of wavelength from 0.36 microns i... more We have made multicolor photometric observations over the range of wavelength from 0.36 microns in the ultraviolet to 5.0 microns in the infrared, on 1063 stars in the regions of h and x Persei, Pleiades, Hyades, Orion, Praesepe M 67, Scorpio-Centaurus, Coma Berenices and Ursa Major stellar aggregates. Standard relations between V-R and the other colors are obtained by using the UBVRI photometry. These observations also have been used to derive photometric distances. The range in distance covered is over a factor of 100, from nearly 22 parsecs (Ursa Major-nucleus) to nearly 2300 parsecs (double cluster in Perseus). The same photometric results arc also used to define a zero-age main sequence for visual absolute magnitudes. The range in V-R is from -0.15 mag. to +1.00 mag. and the range in absolute magnitude is from, approximately, -4.0 to +7.43.

Research paper thumbnail of A modeling framework for developing networked agents applications

This paper presents a modeling framework for developing multi-agent systems composed by networked... more This paper presents a modeling framework for developing multi-agent systems composed by networked identical agents that interact to perform a collective task. An agent architecture for addressing this kind of distributed problems is presented. Then the component devoted to represent and revise the agent's hybrid (continuous and discrete) state is detailed. The framework is illustrated using a case study dealing with a sensor network application.

Research paper thumbnail of Grand Rounds

Archives of Clinical Neuropsychology, 2009

Research paper thumbnail of An overview of the National Consultative Council of Immunization in Honduras

Research paper thumbnail of Regulatory T cells in patients with systemic lupus erythematosus

Journal of Autoimmunity, 2006

Research paper thumbnail of A Spectroscopic and Photometric Study of the Star Cluster in Coma Berenices; (Spanish Title: Estudio Espectroscópico y Fotométrico del Cúmulo Estelar en Coma Berenices

The present paper combines photoelectric and spectroscopic material to attempt a determination on... more The present paper combines photoelectric and spectroscopic material to attempt a determination on the age of the Coma Berenices star cluster.

Research paper thumbnail of Halpha, O I-photometry of the Hyades and Coma Berenices clusters

Revista Mexicana De Astronomia Y Astrofisica, 1986

This paper presents α(16)Λ(9)-photometry of 30 cluster members of the Hyades and 29 Coma Berenice... more This paper presents α(16)Λ(9)-photometry of 30 cluster members of the Hyades and 29 Coma Berenices stars.

Research paper thumbnail of Clinical and immunological effects of Rituximab in patients with lupus nephritis refractory to conventional therapy: a pilot study

Arthritis Research & Therapy, 2006

Research paper thumbnail of Characterization of mtDNA Haplogroups in 14 Mexican Indigenous Populations

Research paper thumbnail of derecho

Research paper thumbnail of From Genes to Flower Patterns and Evolution: Dynamic Models of Gene Regulatory Networks

Journal of Plant Growth Regulation, 2006

Genes and proteins form complex dynamical systems or gene regulatory networks (GRN) that can reac... more Genes and proteins form complex dynamical systems or gene regulatory networks (GRN) that can reach several steady states (attractors). These may be associated with distinct cell types. In plants, the ABC combinatorial model establishes the necessary gene combinations for floral organ cell specification. We have developed dynamic gene regulatory network (GRN) models to understand how the combinatorial selection of gene activity is established during floral organ primordia specification as a result of the concerted action of ABC and non-ABC genes. Our analyses have shown that the floral organ specification GRN reaches six attractors with gene configurations observed in primordial cell types during early stages of flower development and four that correspond to regions of the inflorescence meristem. This suggests that it is the overall GRN dynamics rather than precise signals that underlie the ABC model. Furthermore, our analyses suggest that the steady states of the GRN are robust to random alterations of the logical functions that define the gene interactions. Here we have updated the GRN model and have systematically altered the outputs of all the logical functions and addressed in which cases the original attractors are recovered. We then reduced the original three-state GRN to a two-state (Boolean) GRN and performed the same systematic perturbation analysis. Interestingly, the Boolean GRN reaches the same number and type of attractors as reached by the three-state GRN, and it responds to perturbations in a qualitatively identical manner as the original GRN. These results suggest that a Boolean model is sufficient to capture the dynamical features of the floral network and provide additional support for the robustness of the floral GRN. These findings further support that the GRN model provides a dynamical explanation for the ABC model and that the floral GRN robustness could be behind the widespread conservation of the floral plan among eudicotyledoneous plants. Other aspects of evolution of flower organ arrangement and ABC gene expression patterns are discussed in the context of the approach proposed here.

Research paper thumbnail of Multicolor Photometry of Stellar Aggregates

We have made multicolor photometric observations over the range of wavelength from 0.36 microns i... more We have made multicolor photometric observations over the range of wavelength from 0.36 microns in the ultraviolet to 5.0 microns in the infrared, on 1063 stars in the regions of h and x Persei, Pleiades, Hyades, Orion, Praesepe M 67, Scorpio-Centaurus, Coma Berenices and Ursa Major stellar aggregates. Standard relations between V-R and the other colors are obtained by using the UBVRI photometry. These observations also have been used to derive photometric distances. The range in distance covered is over a factor of 100, from nearly 22 parsecs (Ursa Major-nucleus) to nearly 2300 parsecs (double cluster in Perseus). The same photometric results arc also used to define a zero-age main sequence for visual absolute magnitudes. The range in V-R is from -0.15 mag. to +1.00 mag. and the range in absolute magnitude is from, approximately, -4.0 to +7.43.

Research paper thumbnail of A modeling framework for developing networked agents applications

This paper presents a modeling framework for developing multi-agent systems composed by networked... more This paper presents a modeling framework for developing multi-agent systems composed by networked identical agents that interact to perform a collective task. An agent architecture for addressing this kind of distributed problems is presented. Then the component devoted to represent and revise the agent's hybrid (continuous and discrete) state is detailed. The framework is illustrated using a case study dealing with a sensor network application.

Research paper thumbnail of Grand Rounds

Archives of Clinical Neuropsychology, 2009

Research paper thumbnail of An overview of the National Consultative Council of Immunization in Honduras

Research paper thumbnail of Regulatory T cells in patients with systemic lupus erythematosus

Journal of Autoimmunity, 2006

Research paper thumbnail of A Spectroscopic and Photometric Study of the Star Cluster in Coma Berenices; (Spanish Title: Estudio Espectroscópico y Fotométrico del Cúmulo Estelar en Coma Berenices

The present paper combines photoelectric and spectroscopic material to attempt a determination on... more The present paper combines photoelectric and spectroscopic material to attempt a determination on the age of the Coma Berenices star cluster.

Research paper thumbnail of Halpha, O I-photometry of the Hyades and Coma Berenices clusters

Revista Mexicana De Astronomia Y Astrofisica, 1986

This paper presents α(16)Λ(9)-photometry of 30 cluster members of the Hyades and 29 Coma Berenice... more This paper presents α(16)Λ(9)-photometry of 30 cluster members of the Hyades and 29 Coma Berenices stars.

Research paper thumbnail of Clinical and immunological effects of Rituximab in patients with lupus nephritis refractory to conventional therapy: a pilot study

Arthritis Research & Therapy, 2006

Research paper thumbnail of Characterization of mtDNA Haplogroups in 14 Mexican Indigenous Populations

Research paper thumbnail of derecho