Mia Newlin - Academia.edu (original) (raw)

Papers by Mia Newlin

BMC research notes, Apr 1, 2024

Background Newer antiretrivirals (ART) have shifted the metabolic experiences of people with HIV ... more Background Newer antiretrivirals (ART) have shifted the metabolic experiences of people with HIV (PWH) from those of wasting syndrome to increases in body mass index (BMI). This study sought to examine the relationship between BMI and ART use among youth with HIV (YWH). Methods Charts from YWH ages 10-24 with at least two documented BMIs at least 6 months apart between 2017 and 2020 were included (N = 44). Statistical analyses were conducted in SAS 9.4. Results Clients were predominately African American (66%) males (73%) aged 19-24 years (64%), with men having sex with men (48%) being the most common mode of transmission. YWH on non-integrase inhibitor (INSTI) regimens had greater absolute increases in BMI compared to those on INSTI regimens (p = 0.03). Fourteen percent of clients using INSTI experienced an increase in BMI class from normal to overweight or overweight to obese; no non-INSTI users changed BMI class. Time since diagnosis and BMI change due to weight gain were positively associated (p = 0.03) among behaviorally-acquired YWH. Conclusions Increasing BMI and changing BMI classes may be more likely among YWH using INSTI. More longitudinal studies inclusive of diet and exercise profiles are needed to understand the relationship between INSTI and YWH BMI.

Journal of Nursing Education and Practice

Covid-19 presented tremendous challenges to healthcare systems throughout the world. In particula... more Covid-19 presented tremendous challenges to healthcare systems throughout the world. In particular, the presence of comorbid conditions became a significant factor due to the greatly increased risk of hospitalization and death in people living with diseases such as Congestive Heart Failure. While the literature has long indicated relationships between psychological challenges (depression and anxiety), the pandemic represented a particular challenge due to the way that it limited individual’s ability to engage in activities outside of the home. While all activities were limited, exercise presented a particular challenge as it is so essential to Congestive Heart Failure self-management. The current study used a quantitative descriptive design to examine the relationship between psychological variables and heart failure self-management. The study indicated relatively mild alterations in depression and anxiety. However, the results indicated a significant relationship between physical a...

Medicine & Science in Sports & Exercise, 2010

Purpose: The purpose of this study was to investigate whether acute exercise will affect serum he... more Purpose: The purpose of this study was to investigate whether acute exercise will affect serum hepcidin levels and iron status in active women. Additionally, two different exercise durations were compared to determine if there is a minimum duration of exercise required to induce changes in the inflammatory markers C-Reactive Protein (CRP) and Interluekin-6 (IL-6) and the iron regulatory peptide hepcidin, as well as changes in ferritin and serum iron. Methods: Twelve active women ages 19-32 participated in this study. Subjects performed an incremental treadmill test to exhaustion to determine VO 2max. Subjects were then required to perform two different submaximal treadmill runs (60 minutes and 120 minutes in duration) at a pace that elicited 65% of their predetermined VO2max. The order of the two submaximal trials was randomized and counterbalanced, and all exercise sessions were completed before noon. Blood samples were obtained immediately prior to, immediately following, and 3, 6, 9 and 24 hours following each of the submaximal runs, for the determination of hemoglobin (Hb), hematocrit (Hct), hepcidin, ferritin, serum iron, CRP and IL-6. Post-exercise measures were corrected for plasma volume shifts. A two-way repeated measures ANOVA (trials X time, 2 X 6) was conducted to examine changes in the measured variables, and differences between the trials and sampling time points. Results: No significant time X trial interactions were observed for any of the measured variables. Significant main effects for time and trial were observed for hepcidin. The mean hepcidin concentration was higher for the 120 minute trial. The results of a one-way ANOVA for each of the trials revealed a significantly increased concentration of hepcidin at 3 hours postexercise for both trials (60 min (

Medicine & Science in Sports & Exercise, 2007

Aviation, Space, and Environmental Medicine, 2012

International Journal of Sport Nutrition and Exercise Metabolism, 2012

Purpose:To investigate the effects of acute exercise on serum hepcidin and iron (sFe) in active w... more Purpose:To investigate the effects of acute exercise on serum hepcidin and iron (sFe) in active women. Changes in interleukin-6 (IL-6), hepcidin, ferritin, and sFe in response to 2 different exercise durations were compared.Methods:Twelve women age 19–32 yr performed 2 treadmill runs (60 and 120 min) at 65% of VO2max. Blood samples were obtained before, immediately after, and 3, 6, 9, and 24 hr after exercise. Two-way repeatedmeasures ANOVA was conducted to examine changes in measured variables. Significance was accepted at p < .05.Results:Significant effects for trial were observed for hepcidin (60 min: 1.15 ± 0.48 nmol/L; 120 min: 2.28 ± 1.44 nmol/L) and for time, with hepcidin significantly increased 3 hr postexercise in both trials (60 min: 3 hr – 1.99 ± 2.00 nmol/L; 120 min: 3 hr – 4.60 ± 4.61 nmol/L). Significant main effects for time occurred for sFe, ferritin, and IL-6. sFe was significantly decreased 9 hr postexercise compared with 3 and 24 hr postexercise. IL-6 was sign...