Michael Sawka - Academia.edu (original) (raw)

Papers by Michael Sawka

Research paper thumbnail of Hydration and blood volume effects on human thermoregulation in the heat: Space applications

Research paper thumbnail of Faculty of 1000 evaluation for Cross Acclimation between Heat and Hypoxia: Heat Acclimation Improves Cellular Tolerance and Exercise Performance in Acute Normobaric Hypoxia

F1000 - Post-publication peer review of the biomedical literature, 2016

Research paper thumbnail of American College of Sports Medicine position stand. The use of blood doping as an ergogenic aid

Medicine and Science in Sports and Exercise, Jun 1, 1996

Osteoporosis is a disease characterized by low bone mass and microarchitectural deterioration of ... more Osteoporosis is a disease characterized by low bone mass and microarchitectural deterioration of bone tissue leading to enhanced bone fragility and a consequent increase in fracture risk. Both men and women are at risk for osteoporotic fractures. However, as osteoporosis is more common in females and more exercise-related research has been directed at reducing the risk of osteoporotic fractures in women, this Position Stand applies specifically to women. Factors that influence fracture risk include skeletal fragility, frequency and severity of falls, and tissue mass surrounding the skeleton. Prevention of osteoporotic fractures, therefore, is focused on the preservation or enhancement of the material and structural properties of bone, the prevention of falls, and the overall improvement of lean tissue mass. The load-bearing capacity of bone reflects both its material properties, such as density and modulus, and the spatial distribution of bone tissue. These features of bone strength are all developed and maintained in part by forces applied to bone during daily activities and exercise. Functional loading through physical activity exerts a positive influence on bone mass in humans. The extent of this influence and the types of programs that induce the most effective osteogenic stimulus are still uncertain. While it is well-established that a marked decrease in physical activity, as in bedrest for example, results in a profound decline in bone mass, improvements in bone mass resulting from increased physical activity are less conclusive. Results vary according to age, hormonal status, nutrition, and exercise prescription. An apparent positive effect of activity on bone is more marked in cross-sectional studies than in prospective studies. Whether this is an example of selection bias or differences in the intensity and duration of the training programs is uncertain at this time. It has long been recognized that changes in bone mass occur more rapidly with unloading than with increased loading. Habitual inactivity results in a downward spiral in all physiologic functions. As women age, the loss of strength, flexibility, and cardiovascular fitness leads to a further decrease in activity. Eventually older individuals may find it impossible to continue the types of activities that provide an adequate load-bearing stimulus to maintain bone mass. Fortunately, it appears that strength and overall fitness can be improved at any age through a carefullly planned exercise program. Unless the ability of the underlying physiologic systems essential for load-bearing activity are restored, it may be difficult for many older women to maintain a level of activity essential for protecting the skeleton from further bone loss. (ABSTRACT TRUNCATED)

Research paper thumbnail of Biological variation of local sweating measures during exercise‐heat stress in heat acclimated humans

Research paper thumbnail of Heat acclimation improves central cardiac function and performance variables in cool environments

Research paper thumbnail of Heat acclimation induces peripheral modifications in cutaneous vascular function in humans

Research paper thumbnail of ACSM Expert Consensus Statement on Exertional Heat Illness: Recognition, Management, and Return to Activity

Current Sports Medicine Reports, 2021

Exertional heat stroke (EHS) is a true medical emergency with potential for organ injury and deat... more Exertional heat stroke (EHS) is a true medical emergency with potential for organ injury and death. This consensus statement emphasizes that optimal exertional heat illness management is promoted by a synchronized chain of survival that promotes rapid recognition and management, as well as communication between care teams. Health care providers should be confident in the definitions, etiologies, and nuances of exertional heat exhaustion, exertional heat injury, and EHS. Identifying the athlete with suspected EHS early in the course, stopping activity (body heat generation), and providing rapid total body cooling are essential for survival, and like any critical life-threatening situation (cardiac arrest, brain stroke, sepsis), time is tissue. Recovery from EHS is variable, and outcomes are likely related to the duration of severe hyperthermia. Most exertional heat illnesses can be prevented with the recognition and modification of well-described risk factors ideally addressed throug...

Research paper thumbnail of Controversies in exertional heat stroke diagnosis, prevention, and treatment

Journal of Applied Physiology, 2019

During the past several decades, the incidence of exertional heat stroke (EHS) has increased dram... more During the past several decades, the incidence of exertional heat stroke (EHS) has increased dramatically. Despite an improved understanding of this syndrome, numerous controversies still exist within the scientific and health professions regarding diagnosis, pathophysiology, risk factors, treatment, and return to physical activity. This review examines the following eight controversies: 1) reliance on core temperature for diagnosing and assessing severity of EHS; 2) hypothalamic damage induces heat stroke and this mediates “thermoregulatory failure” during the immediate recovery period; 3) EHS is a predictable condition primarily resulting from overwhelming heat stress; 4) heat-induced endotoxemia mediates systemic inflammatory response syndrome in all EHS cases; 5) nonsteroidal anti-inflammatory drugs for EHS prevention; 6) EHS shares similar mechanisms with malignant hyperthermia; 7) cooling to a specific body core temperature during treatment for EHS; and 8) return to physical a...

Research paper thumbnail of Dehydration Impairs Accuracy and Increases Brain Activity During a Rhythmic Bimanual Choice Reaction Time Task

Medicine & Science in Sports & Exercise, 2019

Research paper thumbnail of Hypohydration and Muscle Glycogen Resynthesis

Medicine and Science in Sports and Exercise, 1989

Research paper thumbnail of Exercise-induced Dehydration Alters Brain Activation During A Cognitive-motor Task

Medicine & Science in Sports & Exercise, 2015

Research paper thumbnail of Impact Of Hypohydration And Exercise-heat Stress On Brain Structure In Men And Women: 2028 Board #180 June 2, 2: 00 PM - 3: 30 PM

Medicine and science in sports and exercise, 2016

Research paper thumbnail of Heat strain evaluation of chemical protective garments

Aviation, space, and environmental medicine, 2001

The purpose of this study was to compare thermoregulatory and subjective responses of 12 test sub... more The purpose of this study was to compare thermoregulatory and subjective responses of 12 test subjects (10 male, 2 female) wearing 5 different Joint Service Lightweight Integrated Suit Technology (JSLIST) prototype and 3 different currently fielded control chemical/ biological (CB) protective overgarments. The overgarments were compared while subjects attempted to complete 100 min of moderate exercise (400 W) in an environmental chamber (35 degrees C/50% rh). Rectal temperature (Tre), skin temperature, heart rate, sweating rate, and test time, as well as subjective symptoms of heat illness were measured. Data were analyzed for times earlier than 100 min because subjects were not usually able to complete the 100-min trials. At 50 min, of the 3 controls, the Army/Air Force Battledress Overgarment (BDO) imposed significantly greater heat strain (indicated by Tre 37.90 degrees C) than the Marine Saratoga (SAR) (Tre 37.68 degrees C) and Navy Chemical Protective Overgarment (CPO) (Tre 37....

Research paper thumbnail of Exertional heat illnesses

Research paper thumbnail of Influence of Acute Erythrocythemia. On Red Cell Volume, Plasma Volume and Hematological Measures Duung Rest and Exercise-Heat Stress

Medicine & Science in Sports & Exercise, 1986

Research paper thumbnail of Fibrinolytic Activity: Effects of Erythrocyte Reinfusion, High Altitude Maximal Exercise

Medicine & Science in Sports & Exercise, 1995

Research paper thumbnail of Arm Crank Protocols for Determination of Maximal Aerobic Power

Medicine & Science in Sports & Exercise, 1982

Research paper thumbnail of Influence of Aerobic Fitness on the Hypohydration Response to Exercise

Medicine & Science in Sports & Exercise, 1983

Research paper thumbnail of Thermoregulation and Exercise in the Heat

Medicine & Science in Sports & Exercise, 2006

Research paper thumbnail of Post-competition blood lactate concentrations in competitive track cyclists

British Journal of Sports Medicine, 1981

Research paper thumbnail of Hydration and blood volume effects on human thermoregulation in the heat: Space applications

Research paper thumbnail of Faculty of 1000 evaluation for Cross Acclimation between Heat and Hypoxia: Heat Acclimation Improves Cellular Tolerance and Exercise Performance in Acute Normobaric Hypoxia

F1000 - Post-publication peer review of the biomedical literature, 2016

Research paper thumbnail of American College of Sports Medicine position stand. The use of blood doping as an ergogenic aid

Medicine and Science in Sports and Exercise, Jun 1, 1996

Osteoporosis is a disease characterized by low bone mass and microarchitectural deterioration of ... more Osteoporosis is a disease characterized by low bone mass and microarchitectural deterioration of bone tissue leading to enhanced bone fragility and a consequent increase in fracture risk. Both men and women are at risk for osteoporotic fractures. However, as osteoporosis is more common in females and more exercise-related research has been directed at reducing the risk of osteoporotic fractures in women, this Position Stand applies specifically to women. Factors that influence fracture risk include skeletal fragility, frequency and severity of falls, and tissue mass surrounding the skeleton. Prevention of osteoporotic fractures, therefore, is focused on the preservation or enhancement of the material and structural properties of bone, the prevention of falls, and the overall improvement of lean tissue mass. The load-bearing capacity of bone reflects both its material properties, such as density and modulus, and the spatial distribution of bone tissue. These features of bone strength are all developed and maintained in part by forces applied to bone during daily activities and exercise. Functional loading through physical activity exerts a positive influence on bone mass in humans. The extent of this influence and the types of programs that induce the most effective osteogenic stimulus are still uncertain. While it is well-established that a marked decrease in physical activity, as in bedrest for example, results in a profound decline in bone mass, improvements in bone mass resulting from increased physical activity are less conclusive. Results vary according to age, hormonal status, nutrition, and exercise prescription. An apparent positive effect of activity on bone is more marked in cross-sectional studies than in prospective studies. Whether this is an example of selection bias or differences in the intensity and duration of the training programs is uncertain at this time. It has long been recognized that changes in bone mass occur more rapidly with unloading than with increased loading. Habitual inactivity results in a downward spiral in all physiologic functions. As women age, the loss of strength, flexibility, and cardiovascular fitness leads to a further decrease in activity. Eventually older individuals may find it impossible to continue the types of activities that provide an adequate load-bearing stimulus to maintain bone mass. Fortunately, it appears that strength and overall fitness can be improved at any age through a carefullly planned exercise program. Unless the ability of the underlying physiologic systems essential for load-bearing activity are restored, it may be difficult for many older women to maintain a level of activity essential for protecting the skeleton from further bone loss. (ABSTRACT TRUNCATED)

Research paper thumbnail of Biological variation of local sweating measures during exercise‐heat stress in heat acclimated humans

Research paper thumbnail of Heat acclimation improves central cardiac function and performance variables in cool environments

Research paper thumbnail of Heat acclimation induces peripheral modifications in cutaneous vascular function in humans

Research paper thumbnail of ACSM Expert Consensus Statement on Exertional Heat Illness: Recognition, Management, and Return to Activity

Current Sports Medicine Reports, 2021

Exertional heat stroke (EHS) is a true medical emergency with potential for organ injury and deat... more Exertional heat stroke (EHS) is a true medical emergency with potential for organ injury and death. This consensus statement emphasizes that optimal exertional heat illness management is promoted by a synchronized chain of survival that promotes rapid recognition and management, as well as communication between care teams. Health care providers should be confident in the definitions, etiologies, and nuances of exertional heat exhaustion, exertional heat injury, and EHS. Identifying the athlete with suspected EHS early in the course, stopping activity (body heat generation), and providing rapid total body cooling are essential for survival, and like any critical life-threatening situation (cardiac arrest, brain stroke, sepsis), time is tissue. Recovery from EHS is variable, and outcomes are likely related to the duration of severe hyperthermia. Most exertional heat illnesses can be prevented with the recognition and modification of well-described risk factors ideally addressed throug...

Research paper thumbnail of Controversies in exertional heat stroke diagnosis, prevention, and treatment

Journal of Applied Physiology, 2019

During the past several decades, the incidence of exertional heat stroke (EHS) has increased dram... more During the past several decades, the incidence of exertional heat stroke (EHS) has increased dramatically. Despite an improved understanding of this syndrome, numerous controversies still exist within the scientific and health professions regarding diagnosis, pathophysiology, risk factors, treatment, and return to physical activity. This review examines the following eight controversies: 1) reliance on core temperature for diagnosing and assessing severity of EHS; 2) hypothalamic damage induces heat stroke and this mediates “thermoregulatory failure” during the immediate recovery period; 3) EHS is a predictable condition primarily resulting from overwhelming heat stress; 4) heat-induced endotoxemia mediates systemic inflammatory response syndrome in all EHS cases; 5) nonsteroidal anti-inflammatory drugs for EHS prevention; 6) EHS shares similar mechanisms with malignant hyperthermia; 7) cooling to a specific body core temperature during treatment for EHS; and 8) return to physical a...

Research paper thumbnail of Dehydration Impairs Accuracy and Increases Brain Activity During a Rhythmic Bimanual Choice Reaction Time Task

Medicine & Science in Sports & Exercise, 2019

Research paper thumbnail of Hypohydration and Muscle Glycogen Resynthesis

Medicine and Science in Sports and Exercise, 1989

Research paper thumbnail of Exercise-induced Dehydration Alters Brain Activation During A Cognitive-motor Task

Medicine & Science in Sports & Exercise, 2015

Research paper thumbnail of Impact Of Hypohydration And Exercise-heat Stress On Brain Structure In Men And Women: 2028 Board #180 June 2, 2: 00 PM - 3: 30 PM

Medicine and science in sports and exercise, 2016

Research paper thumbnail of Heat strain evaluation of chemical protective garments

Aviation, space, and environmental medicine, 2001

The purpose of this study was to compare thermoregulatory and subjective responses of 12 test sub... more The purpose of this study was to compare thermoregulatory and subjective responses of 12 test subjects (10 male, 2 female) wearing 5 different Joint Service Lightweight Integrated Suit Technology (JSLIST) prototype and 3 different currently fielded control chemical/ biological (CB) protective overgarments. The overgarments were compared while subjects attempted to complete 100 min of moderate exercise (400 W) in an environmental chamber (35 degrees C/50% rh). Rectal temperature (Tre), skin temperature, heart rate, sweating rate, and test time, as well as subjective symptoms of heat illness were measured. Data were analyzed for times earlier than 100 min because subjects were not usually able to complete the 100-min trials. At 50 min, of the 3 controls, the Army/Air Force Battledress Overgarment (BDO) imposed significantly greater heat strain (indicated by Tre 37.90 degrees C) than the Marine Saratoga (SAR) (Tre 37.68 degrees C) and Navy Chemical Protective Overgarment (CPO) (Tre 37....

Research paper thumbnail of Exertional heat illnesses

Research paper thumbnail of Influence of Acute Erythrocythemia. On Red Cell Volume, Plasma Volume and Hematological Measures Duung Rest and Exercise-Heat Stress

Medicine & Science in Sports & Exercise, 1986

Research paper thumbnail of Fibrinolytic Activity: Effects of Erythrocyte Reinfusion, High Altitude Maximal Exercise

Medicine & Science in Sports & Exercise, 1995

Research paper thumbnail of Arm Crank Protocols for Determination of Maximal Aerobic Power

Medicine & Science in Sports & Exercise, 1982

Research paper thumbnail of Influence of Aerobic Fitness on the Hypohydration Response to Exercise

Medicine & Science in Sports & Exercise, 1983

Research paper thumbnail of Thermoregulation and Exercise in the Heat

Medicine & Science in Sports & Exercise, 2006

Research paper thumbnail of Post-competition blood lactate concentrations in competitive track cyclists

British Journal of Sports Medicine, 1981