Michelle Smith - Academia.edu (original) (raw)

Papers by Michelle Smith

Childhood in Edwardian Fiction, 2009

The preceding quotation is an example of the way in which the Edwardian school novels of Angela B... more The preceding quotation is an example of the way in which the Edwardian school novels of Angela Brazil celebrated the contemporary idea of less restricted girlhood, while still providing a sense of restraint in a somewhat segregated feminine world. Brazil’s stories are representative of a new style of schoolgirl novel, with a less formal tone and, as Gillian Avery notes, a unique schoolgirl vernacular (207). The novels are also significant when considering childhood and pedagogy because of the way they register transitions in physical education and academic curricula for girls. Written in the early twentieth century, after the late-Victorian social and cultural shifts that placed more girls in schools for a longer duration, creating a literate ‘girl’ readership and girls’ culture, Brazil’s stories are a site in which a new vision of juvenile femininity is fully realized. As Sheila Fletcher remarks, Brazil gives her readers … an exciting sense of the changes that were overtaking girls’ schools; and team games, along with the gymnasium, laboratory, and the tentative discussion of careers, appear as emblems of that brave new world which was rising from its Victorian foundations. (78)

Nuclear Medicine Communications, 1994

Nuclear Medicine Communications, 1992

The synovial and bone uptake of tracer in the knees of patients with rheumatoid arthritis (RA) wa... more The synovial and bone uptake of tracer in the knees of patients with rheumatoid arthritis (RA) was quantified using 99Tcm-hexamethyl propylene amine oxime-labelled leucocytes and 99Tcm-methylene diphosphonate (MDP), respectively. Significant neutrophil migration and MDP uptake occurred in the knees of patients with RA irrespective of the disease duration. In all but one patient neutrophil migration was reduced after intra-articular steroid injection. The change in MDP uptake after steroid injection was variable. There was a significant correlation between the percentage reduction in neutrophil migration and pain score, while the latter correlated poorly with the change in MDP uptake. The quantification of the neutrophil component of the inflammatory process is a sensitive index for monitoring RA activity and response to pharmacological interventions, while quantitative bone scintigraphy should not be employed to monitor changes in joint inflammation in patients with RA.

Crystal Growth & Design, 2006

ABSTRACT A systematic structural and spectroscopic examination of the products resulting from coc... more ABSTRACT A systematic structural and spectroscopic examination of the products resulting from cocrystallization reactions between three types of phenyloximes R−CN−OH (where R = H, Me, or CN) and a series of N-heterocyclic hydrogen-bond acceptors demonstrates that the acidity of the oxime -OH hydrogen-bond donor is crucial to the efficacy of the supramolecular assembly process. Cyanophenyloximes are comparable to carboxylic acids, in terms of success rate, whereas the significantly less acidic CH3- and H-substituted analogues are not effective at generating cocrystals despite close similarities in steric and geometric parameters. The importance and validity of using experimental pKa values and calculated electrostatic potential surfaces as a basis for predicting the supramolecular yield of an O−H···N interaction for driving the formation of cocrystals (within a functional group class) is unambiguously established, and six new crystal structures of cocrystals assembled using oxime···heterocycle-based hydrogen bonds are presented.

Victorian Periodicals Review, 2010

Under Charles Peters’ editorship until his death in 1907, the Girl’s Own Paper (1880-1956) reflec... more Under Charles Peters’ editorship until his death in 1907, the Girl’s Own Paper (1880-1956) reflected and responded to its readers’ needs for practical information about employment opportunities. Articles like “On Earning One’s Living,” “Female Clerks and Book-Keepers,” and “Nursing as a Profession” all appeared in the magazine’s first year. The Correspondence sections likewise discussed issues of employment. In response to her letter, “Isolated Hetty,” for example, is asked whether her elderly relatives would be inconvenienced by her seeking employment and, if not, she is advised “to apply to some hospital for nursing” and directed towards other numbers of the GOP, where “much has been said about” nursing as a profession. Alongside these informational articles and advice columns were fictional stories depicting working girls in their struggles to support themselves and their families while also remaining virtuous and pure. Despite this overt support for working girls, however, the p...

Nature, 2001

Nature is the international weekly journal of science: a magazine style journal that publishes fu... more Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and ...

Acta Neurochirurgica, 2003

Nature

The finished sequence of human chromosome 10 comprises a total of 131,666,441 base pairs. It repr... more The finished sequence of human chromosome 10 comprises a total of 131,666,441 base pairs. It represents 99.4% of the euchromatic DNA and includes one megabase of heterochromatic sequence within the pericentromeric region of the short ...

Nature, 2005

The human X chromosome has a unique biology that was shaped by its evolution as the sex chromosom... more The human X chromosome has a unique biology that was shaped by its evolution as the sex chromosome shared by males and females. We have determined 99.3% of the euchromatic sequence of the X chromosome. Our analysis illustrates the ...

Here we present a standard developed by the Genomic Standards Consortium (GSC) for reporting mark... more Here we present a standard developed by the Genomic Standards Consortium (GSC) for reporting marker gene sequences-the minimum information about a marker gene sequence (MIMARKS). We also introduce a system for describing the environment from which a biological sample originates. The 'environmental packages' apply to any genome sequence of known origin and can be used in combination with MIMARKS and other GSC checklists. Finally, to establish a unified standard for describing sequence data and to provide a single point of entry for the scientific community to access and learn about GSC checklists, we present the minimum information about any (x) sequence (MIxS). Adoption of MIxS will enhance our ability to analyze natural genetic diversity documented by massive DNA sequencing efforts from myriad ecosystems in our everchanging biosphere.

Young adults remain the earliest legal target for the tobacco industry. Against this, the existen... more Young adults remain the earliest legal target for the tobacco industry. Against this, the existence of smoking policies would appear to offer some protection to students on campus. However, little research has been conducted into the outcomes of such policies from a student perspective.

Journal of American …, 1998

Identification of attention deficit hyperactivity disorder (ADHD) in adults presents a number of ... more Identification of attention deficit hyperactivity disorder (ADHD) in adults presents a number of problems because there is no one specific diagnostic test for the condition. Given this challenge, clinicians often struggle between restrictive and exclusionary diagnostic methods or overinclusive acceptance that ADHD is a prevalent and disabling problem. A modified version of the Attention Deficit Hyperactivity Rating Scale was administered to 468 students at a large midwestern university. Analysis of the results suggested that the degree of ADHD symptoms in college students is modest and indicated that cutoff scores of 4 for current symptoms of inattention and hyperactivity-impulsivity would be sufficient to identify a college student as distinct from the norm. Although it would be premature to accept the calculated thresholds completely, clinicians should be aware of these differences when evaluating college students for ADHD.

The Journal of Defense Modeling and Simulation: Applications, Methodology, Technology, 2007

The conventional approach to modeling electro-optic sensor systems is to develop separate models ... more The conventional approach to modeling electro-optic sensor systems is to develop separate models for individual systems or classes of system, depending on the detector technology employed in the sensor and the application. However, this ignores commonality in design and in components of these systems. A generic approach is presented for modeling a variety of sensor systems, operating in the infrared waveband, that also allows systems to be modeled with different levels of detail and at different stages of the product ...

When a droplet of water impacts a hydrophobic surface, the drop is often observed to bounce. Howe... more When a droplet of water impacts a hydrophobic surface, the drop is often observed to bounce. However, for about 10 years it has been known that the addition of very small quantities ($100 ppm) of a flexible polymer such as poly-(ethylene oxide) can completely prevent rebound. This effect has for some time been explained in terms of the stretching of polymer chains by a velocity gradient in the fluid, resulting in a transient increase in the so-called ''extensional viscosity.'' Here we show, by measuring the fluid velocity inside the impacting drop, that the extensional viscosity plays no role in the antirebound phenomenon. Using fluorescently labeled DNA we demonstrate that the observed effect is due to the stretching of polymer molecules as the droplet edge sweeps the substrate, retarding the movement of the receding contact line.

Nature, 1999

Knowledge of the complete genomic DNA sequence of an organism allows a systematic approach to def... more Knowledge of the complete genomic DNA sequence of an organism allows a systematic approach to defining its genetic components. The genomic sequence provides access to the complete structures of all genes, including those ...

Journal of Oncology Practice, 2010

Suggest future topic ideas for the series and provide your feedback by sending an e-mail to resea... more Suggest future topic ideas for the series and provide your feedback by sending an e-mail to researchresources@ asco.org.