Mikael Mattsson - Academia.edu (original) (raw)

Papers by Mikael Mattsson

The overall aims of this thesis were to elucidate the circulatory responses to ultra-endurance ex... more The overall aims of this thesis were to elucidate the circulatory responses to ultra-endurance exercise (Adventure Racing), and furthermore, to contribute to the clarification of the so called “exercise-induced cardiac fatigue” in relation to said exercise. An Adventure race (AR) varies in duration from six hours to over six days, in which the participants have to navigate through a number of check-points over a pre-set course, using a combination of three or more endurance/outdoor sports, e.g., cycling, running, and kayaking. This thesis is based on the results from four different protocols; 12- and 24-h (n = 8 and 9, respectively) in a controlled setting with fixed exercise intensity, and 53-h and 5-7-day (n = 15 in each) in field setting under race conditions. The subjects in all protocols were experienced adventure racing athletes, competitive at elite level. Study I and II address the circulatory responses and cardiovascular drift, using methods for monitoring heart rate (HR), ...

Idrott och Kunskap, 2019

Sedan urminnes tider har det varit känt att olika träningsupplägg fungerar bättre för vissa idrot... more Sedan urminnes tider har det varit känt att olika träningsupplägg fungerar bättre för vissa idrottare än för andra. Med modern datainsamling och analytiska tekniker kan vi integrera mätvärden från träning, prestation och resultat, samt subjektiva och biologiska markörer så att de från en sammantagen bild kan ge rekommendationer anpassade till den specifika individen. Detta gör att idrottarna inte bara kan träna, återhämta sig mer effektivt och prestera bättre, utan även undvika skador och sjukdomar. Artikeln belyser att många professionella team samlar in så mycket mätvärden att de lider av en ”data-tsunami”, och hur den senaste vetenskapen och analytiska metoder, inklusive AI och djupinlärning, kan optimera datainsamling och analys för att minimera skador och förbättra prestationen

Pa uppdrag av Forsvarsmakten genomforde Militarmedicinska forskningsgruppen vid Astandlaboratorie... more Pa uppdrag av Forsvarsmakten genomforde Militarmedicinska forskningsgruppen vid Astandlaboratoriet vid Gymnastik- och idrottshogskolan Stockholm (GIH), en observationsstudie gallande fysiologisk/me ...

Den militarmedicinska forskningsgruppen vid Astrandlaboratoriet, Gymnastik- och Idrottshogskolan,... more Den militarmedicinska forskningsgruppen vid Astrandlaboratoriet, Gymnastik- och Idrottshogskolan, Stockholm, har som forskningsuppgift med stod fran Forsvarsmakten att studera och foresla insatser ...

The hypothesis that ultraendurance exercise influences muscle mitochondrial function has been inv... more The hypothesis that ultraendurance exercise influences muscle mitochondrial function has been investigated. Athletes in ultraendurance performance performed running, kayaking, and cycling at 60% of their peak O 2 consumption for 24 h. Muscle biopsies were taken preexercise (Pre-Ex), postexercise (Post-Ex), and after 28 h of recovery (Rec). Respiration was analyzed in isolated mitochondria during state 3 (coupled to ATP synthesis) and state 4 (noncoupled respiration), with fatty acids alone [palmitoyl carnitine (PC)] or together with pyruvate (Pyr). Electron transport chain activity was measured with NADH in permeabilized mitochondria. State 3 respiration with PC increased Post-Ex by 39 and 41% (P Ͻ 0.05) when related to mitochondrial protein and to electron transport chain activity, respectively. State 3 respiration with Pyr was not changed (P Ͼ 0.05). State 4 respiration with PC increased Post-Ex but was lower than Pre-Ex at Rec (P Ͻ 0.05 vs. Pre-Ex). Mitochondrial efficiency [amount of added ADP divided by oxygen consumed during state 3 (P/O ratio)] decreased Post-Ex by 9 and 6% (P Ͻ 0.05) with PC and PC ϩ Pyr, respectively. P/O ratio remained reduced at Rec. Muscle uncoupling protein 3, measured with Western blotting, was not changed Post-Ex but tended to decrease at Rec (P ϭ 0.07 vs. Pre-Ex). In conclusion, extreme endurance exercise decreases mitochondrial efficiency. This will increase oxygen demand and may partly explain the observed elevation in whole body oxygen consumption during standardized exercise (ϩ13%). The increased mitochondrial capacity for PC oxidation indicates plasticity in substrate oxidation at the mitochondrial level, which may be of advantage during prolonged exercise.

Rekommendationer gallande barvikter och forflyttningshastigheter under langre faltoperationer. Be... more Rekommendationer gallande barvikter och forflyttningshastigheter under langre faltoperationer. Berakningar av energiomsattning

Nitton manliga valtranade forsokspersoner, 9 st med vana att bara tungt och 10 st utan sadan vana... more Nitton manliga valtranade forsokspersoner, 9 st med vana att bara tungt och 10 st utan sadan vana, genomforde gang pa mjukt underlag i hastigheterna 3 och 5 km/tim med barvikter i ryggsack pa 20, 3 ...

Sports Medicine - Open, 2018

Background: Strength and power development are abilities important for athletic performance in ma... more Background: Strength and power development are abilities important for athletic performance in many sports. Generally, resistance training based on gravity is used to improve these qualities. Flywheel training instead utilizes kinetic energy transferred to a flywheel. This allows for eccentric overload and variable resistance throughout the movement. The aim of this review was to identify the effects of flywheel training on multiple strength-related variables affecting athletic performance. The meta-analysis investigates the effects on (1) muscle growth (cross-sectional area (CSA) and volume/mass), (2) maximum dynamic strength, (3) development of power, (4) development of horizontal movement, and (5) development of vertical movement. Methods: The meta-analysis includes 20 experimental studies that met the inclusion criteria. The quality of included studies was ranked according to the PEDro scale. Possible bias was identified in Funnel plot analyses. To enable the compilation of all results analyses, the random effect model was carried out using the software Review Manager Version 5.3 and presented with Forest plots. Results: Flywheel training for a period of 4-24 weeks shows statistically significant increases in all strength aspects. Effect sizes were for hypertrophy, CSA 0.59; volume/mass 0.59; maximum strength 1.33; power 1.19; horizontal 1.01 and vertical movement 0.85. The evidence is particularly strong for beneficial effects from flywheel training in the development of maximal strength and power in trained younger individuals, and utilization of this training modality in shorter more intensive blocks. Conclusions: Flywheel training is an effective method for improving several aspects of strength and power with importance for sports performance.

The energy expenditure during carrying no load, 20, 35 and 50 kg at two walking speeds, 3 and 5 k... more The energy expenditure during carrying no load, 20, 35 and 50 kg at two walking speeds, 3 and 5 km/h, was studied in 36 healthy participants, 19 men (30 ± 6 yrs, 82.5 ± 7.0 kg) and 17 women (29 ± 6 yrs, 66.1 ± 8.9 kg). Anthropometric data, leg muscle strength as well as trunk muscle endurance and muscle fibre distribution of the thigh were also obtained. To load the participant a standard backpack filled with extra weight according to the carrying weight tested was used. Extra Load Index (ELI), the oxygen uptake (VO2) during total load over no-load-exercise, was used as a proxy for load carrying ability. In addition to analyzing factors of importance for the ELI values, we also conducted mediator analyzes using sex and long term carrying experience as causal variables for ELI as the outcome value. For the lowest load (20 kg), ELI20, was correlated with body mass but no other factors. Walking at 5 km/h body mass, body height, leg muscle strength and absolute VO2max were correlated to...

PloS one, 2017

Physiological and medical effects of snuff have previously been obtained either in cross-sectiona... more Physiological and medical effects of snuff have previously been obtained either in cross-sectional studies or after snuff administration to non-tobacco users. The effects of snuff cessation after several years of daily use are unknown. 24 participants with >2 years of daily snuff-use were tested before and after >6 weeks snuff cessation (SCG). A control group (CO) of 11 snuff users kept their normal habits. Resting heart rate (HR) and blood pressure (BP) were significantly lower in SCG after snuff cessation, and body mass was increased by 1.4 ± 1.7 kg. Total cholesterol increased from 4.12 ± 0.54 (95% CI 3.89-4.35) to 4.46 ± 0.70 (95% CI 4.16-4.75) mM L-1 in SCG, due to increased LDL, and this change was significantly different from CO. Resting values of HDL, C-reactive protein, and free fatty acids (FFA) remained unchanged in both groups. In SCG group, both HR and BP were reduced during a four-stage incremental cycling test (from 50 to 80% of VO2max) and a prolonged cycling t...

BackgroundThe ability to measure activity and physiology through wrist-worn devices provides an o... more BackgroundThe ability to measure activity and physiology through wrist-worn devices provides an opportunity for cardiovascular medicine. However, the accuracy of commercial devices is largely unknown.ObjectiveTo assess the accuracy of seven commercially available wrist-worn devices in estimating heart rate (HR) and energy expenditure (EE) and to propose a wearable sensor evaluation framework.MethodsWe evaluated the Apple Watch, Basis Peak, Fitbit Surge, Microsoft Band, Mio Alpha 2, PulseOn, and Samsung Gear S2. Participants wore devices while being simultaneously assessed with continuous telemetry and indirect calorimetry while sitting, walking, running, and cycling. Sixty volunteers (29 male, 31 female, age 38 ± 11 years) of diverse age, height, weight, skin tone, and fitness level were selected. Error in HR and EE was computed for each subject/device/activity combination.ResultsDevices reported the lowest error for cycling and the highest for walking. Device error was higher for m...

Physiological Genomics, 2016

Sports genetics can take advantage of lessons learned from human disease genetics. By righting pa... more Sports genetics can take advantage of lessons learned from human disease genetics. By righting past mistakes and increasing scientific rigor, we can magnify the breadth and depth of knowledge in the field. We present an outline of challenges facing sports genetics in the light of experiences from medical research. Sports performance is complex, resulting from a combination of a wide variety of different traits and attributes. Improving sports genetics will foremost require analyses based on detailed phenotyping. To find widely valid, reproducible common variants associated with athletic phenotypes, study sample sizes must be dramatically increased. One paradox is that in order to confirm relevance, replications in specific populations must be undertaken. Family studies of athletes may facilitate the discovery of rare variants with large effects on athletic phenotypes. The complexity of the human genome, combined with the complexity of athletic phenotypes, will require additional met...

Journal of Applied Sport Psychology, 2014

ABSTRACT This study explores nonverbal behaviors in the form of gestures and touch during elite h... more ABSTRACT This study explores nonverbal behaviors in the form of gestures and touch during elite handball matches. Based on a coding scheme, 616 postshot periods following a goal, stemming from 18 matches, were analyzed. Results revealed that, on average, 2.77 nonverbal behaviors were displayed after scoring. Play-off matches resulted in a higher average of nonverbal behaviors than league matches. The more a team was leading by, the higher the overall number of nonverbal behaviors; meanwhile, the overall amount of nonverbal behaviors declined over the course of a match. The results pinpoint to the situation specificity of nonverbal behaviors during ongoing matches.

Fa medicinska underokningar har sa lang tradition och sa stor symbolisk betydelse som ett EKG (el... more Fa medicinska underokningar har sa lang tradition och sa stor symbolisk betydelse som ett EKG (elektrokardiogram). Hjartat ar ju sjalva symbolen for liv, och ett normalt EKG ar en viktig del i att ...

From a team sport perspective, players’ emotional expressions can have a detrimental impact on te... more From a team sport perspective, players’ emotional expressions can have a detrimental impact on team performance through a process called emotional contagion (Hatfield et al., 1994). Moll et al. (20 ...

The overall aims of this thesis were to elucidate the circulatory responses to ultra-endurance ex... more The overall aims of this thesis were to elucidate the circulatory responses to ultra-endurance exercise (Adventure Racing), and furthermore, to contribute to the clarification of the so called “exercise-induced cardiac fatigue” in relation to said exercise. An Adventure race (AR) varies in duration from six hours to over six days, in which the participants have to navigate through a number of check-points over a pre-set course, using a combination of three or more endurance/outdoor sports, e.g., cycling, running, and kayaking. This thesis is based on the results from four different protocols; 12- and 24-h (n = 8 and 9, respectively) in a controlled setting with fixed exercise intensity, and 53-h and 5-7-day (n = 15 in each) in field setting under race conditions. The subjects in all protocols were experienced adventure racing athletes, competitive at elite level. Study I and II address the circulatory responses and cardiovascular drift, using methods for monitoring heart rate (HR), ...

Idrott och Kunskap, 2019

Sedan urminnes tider har det varit känt att olika träningsupplägg fungerar bättre för vissa idrot... more Sedan urminnes tider har det varit känt att olika träningsupplägg fungerar bättre för vissa idrottare än för andra. Med modern datainsamling och analytiska tekniker kan vi integrera mätvärden från träning, prestation och resultat, samt subjektiva och biologiska markörer så att de från en sammantagen bild kan ge rekommendationer anpassade till den specifika individen. Detta gör att idrottarna inte bara kan träna, återhämta sig mer effektivt och prestera bättre, utan även undvika skador och sjukdomar. Artikeln belyser att många professionella team samlar in så mycket mätvärden att de lider av en ”data-tsunami”, och hur den senaste vetenskapen och analytiska metoder, inklusive AI och djupinlärning, kan optimera datainsamling och analys för att minimera skador och förbättra prestationen

Pa uppdrag av Forsvarsmakten genomforde Militarmedicinska forskningsgruppen vid Astandlaboratorie... more Pa uppdrag av Forsvarsmakten genomforde Militarmedicinska forskningsgruppen vid Astandlaboratoriet vid Gymnastik- och idrottshogskolan Stockholm (GIH), en observationsstudie gallande fysiologisk/me ...

Den militarmedicinska forskningsgruppen vid Astrandlaboratoriet, Gymnastik- och Idrottshogskolan,... more Den militarmedicinska forskningsgruppen vid Astrandlaboratoriet, Gymnastik- och Idrottshogskolan, Stockholm, har som forskningsuppgift med stod fran Forsvarsmakten att studera och foresla insatser ...

The hypothesis that ultraendurance exercise influences muscle mitochondrial function has been inv... more The hypothesis that ultraendurance exercise influences muscle mitochondrial function has been investigated. Athletes in ultraendurance performance performed running, kayaking, and cycling at 60% of their peak O 2 consumption for 24 h. Muscle biopsies were taken preexercise (Pre-Ex), postexercise (Post-Ex), and after 28 h of recovery (Rec). Respiration was analyzed in isolated mitochondria during state 3 (coupled to ATP synthesis) and state 4 (noncoupled respiration), with fatty acids alone [palmitoyl carnitine (PC)] or together with pyruvate (Pyr). Electron transport chain activity was measured with NADH in permeabilized mitochondria. State 3 respiration with PC increased Post-Ex by 39 and 41% (P Ͻ 0.05) when related to mitochondrial protein and to electron transport chain activity, respectively. State 3 respiration with Pyr was not changed (P Ͼ 0.05). State 4 respiration with PC increased Post-Ex but was lower than Pre-Ex at Rec (P Ͻ 0.05 vs. Pre-Ex). Mitochondrial efficiency [amount of added ADP divided by oxygen consumed during state 3 (P/O ratio)] decreased Post-Ex by 9 and 6% (P Ͻ 0.05) with PC and PC ϩ Pyr, respectively. P/O ratio remained reduced at Rec. Muscle uncoupling protein 3, measured with Western blotting, was not changed Post-Ex but tended to decrease at Rec (P ϭ 0.07 vs. Pre-Ex). In conclusion, extreme endurance exercise decreases mitochondrial efficiency. This will increase oxygen demand and may partly explain the observed elevation in whole body oxygen consumption during standardized exercise (ϩ13%). The increased mitochondrial capacity for PC oxidation indicates plasticity in substrate oxidation at the mitochondrial level, which may be of advantage during prolonged exercise.

Rekommendationer gallande barvikter och forflyttningshastigheter under langre faltoperationer. Be... more Rekommendationer gallande barvikter och forflyttningshastigheter under langre faltoperationer. Berakningar av energiomsattning

Nitton manliga valtranade forsokspersoner, 9 st med vana att bara tungt och 10 st utan sadan vana... more Nitton manliga valtranade forsokspersoner, 9 st med vana att bara tungt och 10 st utan sadan vana, genomforde gang pa mjukt underlag i hastigheterna 3 och 5 km/tim med barvikter i ryggsack pa 20, 3 ...

Sports Medicine - Open, 2018

Background: Strength and power development are abilities important for athletic performance in ma... more Background: Strength and power development are abilities important for athletic performance in many sports. Generally, resistance training based on gravity is used to improve these qualities. Flywheel training instead utilizes kinetic energy transferred to a flywheel. This allows for eccentric overload and variable resistance throughout the movement. The aim of this review was to identify the effects of flywheel training on multiple strength-related variables affecting athletic performance. The meta-analysis investigates the effects on (1) muscle growth (cross-sectional area (CSA) and volume/mass), (2) maximum dynamic strength, (3) development of power, (4) development of horizontal movement, and (5) development of vertical movement. Methods: The meta-analysis includes 20 experimental studies that met the inclusion criteria. The quality of included studies was ranked according to the PEDro scale. Possible bias was identified in Funnel plot analyses. To enable the compilation of all results analyses, the random effect model was carried out using the software Review Manager Version 5.3 and presented with Forest plots. Results: Flywheel training for a period of 4-24 weeks shows statistically significant increases in all strength aspects. Effect sizes were for hypertrophy, CSA 0.59; volume/mass 0.59; maximum strength 1.33; power 1.19; horizontal 1.01 and vertical movement 0.85. The evidence is particularly strong for beneficial effects from flywheel training in the development of maximal strength and power in trained younger individuals, and utilization of this training modality in shorter more intensive blocks. Conclusions: Flywheel training is an effective method for improving several aspects of strength and power with importance for sports performance.

The energy expenditure during carrying no load, 20, 35 and 50 kg at two walking speeds, 3 and 5 k... more The energy expenditure during carrying no load, 20, 35 and 50 kg at two walking speeds, 3 and 5 km/h, was studied in 36 healthy participants, 19 men (30 ± 6 yrs, 82.5 ± 7.0 kg) and 17 women (29 ± 6 yrs, 66.1 ± 8.9 kg). Anthropometric data, leg muscle strength as well as trunk muscle endurance and muscle fibre distribution of the thigh were also obtained. To load the participant a standard backpack filled with extra weight according to the carrying weight tested was used. Extra Load Index (ELI), the oxygen uptake (VO2) during total load over no-load-exercise, was used as a proxy for load carrying ability. In addition to analyzing factors of importance for the ELI values, we also conducted mediator analyzes using sex and long term carrying experience as causal variables for ELI as the outcome value. For the lowest load (20 kg), ELI20, was correlated with body mass but no other factors. Walking at 5 km/h body mass, body height, leg muscle strength and absolute VO2max were correlated to...

PloS one, 2017

Physiological and medical effects of snuff have previously been obtained either in cross-sectiona... more Physiological and medical effects of snuff have previously been obtained either in cross-sectional studies or after snuff administration to non-tobacco users. The effects of snuff cessation after several years of daily use are unknown. 24 participants with >2 years of daily snuff-use were tested before and after >6 weeks snuff cessation (SCG). A control group (CO) of 11 snuff users kept their normal habits. Resting heart rate (HR) and blood pressure (BP) were significantly lower in SCG after snuff cessation, and body mass was increased by 1.4 ± 1.7 kg. Total cholesterol increased from 4.12 ± 0.54 (95% CI 3.89-4.35) to 4.46 ± 0.70 (95% CI 4.16-4.75) mM L-1 in SCG, due to increased LDL, and this change was significantly different from CO. Resting values of HDL, C-reactive protein, and free fatty acids (FFA) remained unchanged in both groups. In SCG group, both HR and BP were reduced during a four-stage incremental cycling test (from 50 to 80% of VO2max) and a prolonged cycling t...

BackgroundThe ability to measure activity and physiology through wrist-worn devices provides an o... more BackgroundThe ability to measure activity and physiology through wrist-worn devices provides an opportunity for cardiovascular medicine. However, the accuracy of commercial devices is largely unknown.ObjectiveTo assess the accuracy of seven commercially available wrist-worn devices in estimating heart rate (HR) and energy expenditure (EE) and to propose a wearable sensor evaluation framework.MethodsWe evaluated the Apple Watch, Basis Peak, Fitbit Surge, Microsoft Band, Mio Alpha 2, PulseOn, and Samsung Gear S2. Participants wore devices while being simultaneously assessed with continuous telemetry and indirect calorimetry while sitting, walking, running, and cycling. Sixty volunteers (29 male, 31 female, age 38 ± 11 years) of diverse age, height, weight, skin tone, and fitness level were selected. Error in HR and EE was computed for each subject/device/activity combination.ResultsDevices reported the lowest error for cycling and the highest for walking. Device error was higher for m...

Physiological Genomics, 2016

Sports genetics can take advantage of lessons learned from human disease genetics. By righting pa... more Sports genetics can take advantage of lessons learned from human disease genetics. By righting past mistakes and increasing scientific rigor, we can magnify the breadth and depth of knowledge in the field. We present an outline of challenges facing sports genetics in the light of experiences from medical research. Sports performance is complex, resulting from a combination of a wide variety of different traits and attributes. Improving sports genetics will foremost require analyses based on detailed phenotyping. To find widely valid, reproducible common variants associated with athletic phenotypes, study sample sizes must be dramatically increased. One paradox is that in order to confirm relevance, replications in specific populations must be undertaken. Family studies of athletes may facilitate the discovery of rare variants with large effects on athletic phenotypes. The complexity of the human genome, combined with the complexity of athletic phenotypes, will require additional met...

Journal of Applied Sport Psychology, 2014

ABSTRACT This study explores nonverbal behaviors in the form of gestures and touch during elite h... more ABSTRACT This study explores nonverbal behaviors in the form of gestures and touch during elite handball matches. Based on a coding scheme, 616 postshot periods following a goal, stemming from 18 matches, were analyzed. Results revealed that, on average, 2.77 nonverbal behaviors were displayed after scoring. Play-off matches resulted in a higher average of nonverbal behaviors than league matches. The more a team was leading by, the higher the overall number of nonverbal behaviors; meanwhile, the overall amount of nonverbal behaviors declined over the course of a match. The results pinpoint to the situation specificity of nonverbal behaviors during ongoing matches.

Fa medicinska underokningar har sa lang tradition och sa stor symbolisk betydelse som ett EKG (el... more Fa medicinska underokningar har sa lang tradition och sa stor symbolisk betydelse som ett EKG (elektrokardiogram). Hjartat ar ju sjalva symbolen for liv, och ett normalt EKG ar en viktig del i att ...

From a team sport perspective, players’ emotional expressions can have a detrimental impact on te... more From a team sport perspective, players’ emotional expressions can have a detrimental impact on team performance through a process called emotional contagion (Hatfield et al., 1994). Moll et al. (20 ...