Mitali Shinde - Academia.edu (original) (raw)

Papers by Mitali Shinde

Journal of Clinical and Experimental Dentistry, 2020

Background: Stevia is a natural sweetener which is used as sugar substitute. It has been suggeste... more Background: Stevia is a natural sweetener which is used as sugar substitute. It has been suggested that stevia may be anticariogenic. However, there is limited research in this regard. Hence, the present study was designed to assess reduction in S. mutans in stevia and xylitol chewing gums. The aim of this study is to evaluate the effectiveness of stevia and xylitol chewing gums on salivary Streptococcus mutans count. Material and Methods: A randomized triple blinded clinical study with a crossover design included twenty healthy children aged 8-13 years with decayed, missing, and filled teeth (dmft)/DMFT index score ≥ 3. Before the test, unstimulated saliva was collected. Children divided into Group I and II were given Stevia and Xylitol chewing gums respectively. Saliva samples were then collected at 15 min (just after spitting) and after 1 h. The amount of S. mutans in saliva was evaluated using a selective media (TYCSB). The data were subjected to statistical analysis using statistical software IBM SPSS statistics 20.0 (IBM Corporation, Armonk, NY, USA) Results: Reduction in S. mutans was seen from baseline to 1 hour in both groups in trial and crossover design though intergroup comparison was not statistically significant. There was reduction seen from baseline to 15 minutes and 15 minutes to 1 hour in xylitol and stevia group both in trial and crossover design which was statistically significant. Conclusions: Stevia containing chewing gum is equally effective to Xylitol chewing gum in reducing salivary S. mutans counts.

Journal of Drug Delivery and Therapeutics, 2020

A wide range of artificial and synthetic products have been replaced by the natural products for ... more A wide range of artificial and synthetic products have been replaced by the natural products for daily use. The natural products are believed to have more advantages and less adverse effects. The plant products such as stem, flower, fruit, seed, leaves, etc have been experimented. Stevia rebaudiana Bertoni, a perennial shrub which is a native of South America. During World War II, England used it as a sweetener as sugar was not available. By 1970, it was used as a sweetener in Japan. In 1994, US approved steviol glycosides as functional ingredient in dietary supplements. It is non-caloric sweetener which is 200-300 times sweeter than table sugar. Its use as a sweetener was approved by FDA in 2011. There is growing evidence supporting the use of stevia in diabetes, hypertension, weight loss, etc. Dental caries is an infectious microbiologic disease of the tooth that results in localized dissolution and destruction of calcified tissues. There has been an increased interest on antimicr...

Journal of Dental Research and Review, 2020

Context: Stevia is a natural sweetener which is used as a sugar substitute. There is limited rese... more Context: Stevia is a natural sweetener which is used as a sugar substitute. There is limited research regarding the use of stevia chewing gum and its effect on salivary flow rate and pH. Aim: The aim of the study was to assess the effect of stevia and xylitol chewing gums on salivary flow rate, pH, and its taste acceptance. Setting and Design: A randomized, triple-blinded, clinical study with a crossover design was conducted. Subjects and Methods: Twenty children aged 8–13 years with decayed, missing, and filled teeth index score ≥3 were selected. Pretest unstimulated saliva was collected. The children were divided into two groups, and Stevia and Xylitol gums were provided to each group to chew for 15 min. Salivary samples were collected at 15 min and 1 h. Salivary flow rate and pH were measured at baseline, 15 min, and 1 h. Statistical Analysis: The collected data were subjected to statistical analysis using Wilcoxon signed-rank test, and P ≤ 0.05 was considered statistically signi...

Journal of Clinical and Experimental Dentistry, 2020

Background: Stevia is a natural sweetener which is used as sugar substitute. It has been suggeste... more Background: Stevia is a natural sweetener which is used as sugar substitute. It has been suggested that stevia may be anticariogenic. However, there is limited research in this regard. Hence, the present study was designed to assess reduction in S. mutans in stevia and xylitol chewing gums. The aim of this study is to evaluate the effectiveness of stevia and xylitol chewing gums on salivary Streptococcus mutans count. Material and Methods: A randomized triple blinded clinical study with a crossover design included twenty healthy children aged 8-13 years with decayed, missing, and filled teeth (dmft)/DMFT index score ≥ 3. Before the test, unstimulated saliva was collected. Children divided into Group I and II were given Stevia and Xylitol chewing gums respectively. Saliva samples were then collected at 15 min (just after spitting) and after 1 h. The amount of S. mutans in saliva was evaluated using a selective media (TYCSB). The data were subjected to statistical analysis using statistical software IBM SPSS statistics 20.0 (IBM Corporation, Armonk, NY, USA) Results: Reduction in S. mutans was seen from baseline to 1 hour in both groups in trial and crossover design though intergroup comparison was not statistically significant. There was reduction seen from baseline to 15 minutes and 15 minutes to 1 hour in xylitol and stevia group both in trial and crossover design which was statistically significant. Conclusions: Stevia containing chewing gum is equally effective to Xylitol chewing gum in reducing salivary S. mutans counts.

Journal of Drug Delivery and Therapeutics, 2020

A wide range of artificial and synthetic products have been replaced by the natural products for ... more A wide range of artificial and synthetic products have been replaced by the natural products for daily use. The natural products are believed to have more advantages and less adverse effects. The plant products such as stem, flower, fruit, seed, leaves, etc have been experimented. Stevia rebaudiana Bertoni, a perennial shrub which is a native of South America. During World War II, England used it as a sweetener as sugar was not available. By 1970, it was used as a sweetener in Japan. In 1994, US approved steviol glycosides as functional ingredient in dietary supplements. It is non-caloric sweetener which is 200-300 times sweeter than table sugar. Its use as a sweetener was approved by FDA in 2011. There is growing evidence supporting the use of stevia in diabetes, hypertension, weight loss, etc. Dental caries is an infectious microbiologic disease of the tooth that results in localized dissolution and destruction of calcified tissues. There has been an increased interest on antimicr...

Journal of Dental Research and Review, 2020

Context: Stevia is a natural sweetener which is used as a sugar substitute. There is limited rese... more Context: Stevia is a natural sweetener which is used as a sugar substitute. There is limited research regarding the use of stevia chewing gum and its effect on salivary flow rate and pH. Aim: The aim of the study was to assess the effect of stevia and xylitol chewing gums on salivary flow rate, pH, and its taste acceptance. Setting and Design: A randomized, triple-blinded, clinical study with a crossover design was conducted. Subjects and Methods: Twenty children aged 8–13 years with decayed, missing, and filled teeth index score ≥3 were selected. Pretest unstimulated saliva was collected. The children were divided into two groups, and Stevia and Xylitol gums were provided to each group to chew for 15 min. Salivary samples were collected at 15 min and 1 h. Salivary flow rate and pH were measured at baseline, 15 min, and 1 h. Statistical Analysis: The collected data were subjected to statistical analysis using Wilcoxon signed-rank test, and P ≤ 0.05 was considered statistically signi...