Mohamed Jawhar - Academia.edu (original) (raw)

Papers by Mohamed Jawhar

Research paper thumbnail of Refined Treatment Response Criteria for Indolent Systemic Mastocytosis Proposed by the ECNM-AIM Consortium

The Journal of Allergy and Clinical Immunology: In Practice

Research paper thumbnail of Diagnostic Yield of PAX5 in Lymphoma

Annals of the College of Medicine, Mosul, 2021

Background: Lymphoma is a heterogeneous group of neoplasm affecting any stage of lymphocyte devel... more Background: Lymphoma is a heterogeneous group of neoplasm affecting any stage of lymphocyte development. Nowadays, WHO (2017) adapted their classification depending on their morphological, immunohistochemical appearance, and their clinical and molecular characteristics. Objective: To determine the expression of PAX5 in Hodgkin and Non Hodgkin lymphoma and their association with clinical parameters (age & site). Patients & Methods: During a period of 1 year starting from June 2019 to June 2020, 60 lymphoma patients" were included in this"prospective-retrospective"case series study from"medical records and histopathological results in governmental and private labs. Immunohistochemistry examination using PAX5 was performed, and data of the positive PAX5 expression were analyzed. Results: A total of 60 patients were recruited in this study with the majority (58%) were Non Hodgkin lymphoma, dominated by diffuse large B-cell lymphoma subtype (42.8%) and (42%) were Hodgkin lymphoma where nodular sclerosis subtype formed (52%) and mainly of the nodal site in both of them. The age range of Non Hodgkin lymphoma 7-76 years (median 50 years) and 5-67 years (median 21 years) for Hodgkin lymphoma and male predominance in both of them and there is no significant association between the site and lymphoma (p value=0.0647) while a significant association with age (p value =0.037). Moreover, the immunohistochemical examination demonstrates that positive PAX5 was expressed in 77% of Non Hodgkin lymphoma and 100% of Hodgkin lymphoma. The P-value between them was 0.016, which was statistically significant ,no matter of using PAX5 or CD30 in"the diagnosis of Hodgkin lymphoma,in other hand"there is a significant difference between PAX5 and CD3 expression (P value=0.004), while it is not statistically significant when comparing PAX5 and CD20 (P-value =0.317) in the diagnosis of Non Hodgkin lymphoma. Conclusion: This study demonstrates that PAX5 is one of the most sensitive and reliable immunohistochemical marker in diagnosing Hodgkin lymphoma and B-cell Non Hodgkin lymphoma.

Research paper thumbnail of Malaysia’s New Minister of Foreign Affairs A TRIANNUAL PUBLICATION OF THE INSTITUTE OF DIPLOMACY AND FOREIGN RELATIONS, MINISTRY OF FOREIGN AFFAIRS, MALAYSIA

The Honourable Dato’ Saifuddin was Deputy Minister for the Ministry of Higher Education from 2009... more The Honourable Dato’ Saifuddin was Deputy Minister for the Ministry of Higher Education from 2009 to 2013, and Deputy Minister for the Ministry of Entrepreneurship and Cooperative Development from 2008 to 2009. He was also Chief Executive Officer of the Global Movement of Moderates Foundation from 2013 to 2015, and has been Patron to the Malaysian Institute of Debate and Public Speaking since 2013. The Honourable Dato’ Saifuddin is a regular columnist with several newspapers, and has written several books on Malaysian politics, including New Politics 2.0: Multiracial and Moderate Malaysian Democracy (2017).

Research paper thumbnail of The Italian Americans

International Migration Review, 1988

Research paper thumbnail of ASEAN's Political and Security Relations with Japan

A combination of developments is making the current moment particularly propitious for the enhanc... more A combination of developments is making the current moment particularly propitious for the enhancement of political and security cooperation between the Association of Southeast Asian Nations (ASEAN) and Japan-as well as between ASEAN and China and, to a lesser degree, ASEAN and South Korea. If carefully exploited and managed well, the potential for furthering peace, prosperity, and well-being in East Asia will be significant. The focus for cooperation within these relationships, however, will remain primarily in the economic area. This is perhaps just as well, because economic cooperation is both more easily attainable and provides more practical dividends for East Asian well-being than would security cooperation. And economic cooperation prepares the ground for political and security cooperation. It is also consistent with the aspirations of the East Asia Vision 2020, to which all the nations involved subscribe. Factors Driving ASEAN-Japan Political and Security Cooperation ASEAN Countries The relations ASEAN countries have maintained with Japan have for some time been driven essentially by economic considerations, and this is unlikely to change in the future. Interest in Japanese investment (cumulative foreign direct investment amounting to US$544 million in 1990-2001),

Research paper thumbnail of Managing security in Southeast Asia: Existing mechanisms and processes to address regional conflicts

Aust J Int Aff, 1993

History, geostrategic location, geopolitical calculations and the involvement of outside powers h... more History, geostrategic location, geopolitical calculations and the involvement of outside powers have all conspired to foster an extremely disparate set of security mechanisms and processes in Southeast Asia. These range from isolationist neutrality in the case of Myanmar to ...

Research paper thumbnail of Refined Treatment Response Criteria for Indolent Systemic Mastocytosis Proposed by the ECNM-AIM Consortium

The Journal of Allergy and Clinical Immunology: In Practice

Research paper thumbnail of Diagnostic Yield of PAX5 in Lymphoma

Annals of the College of Medicine, Mosul, 2021

Background: Lymphoma is a heterogeneous group of neoplasm affecting any stage of lymphocyte devel... more Background: Lymphoma is a heterogeneous group of neoplasm affecting any stage of lymphocyte development. Nowadays, WHO (2017) adapted their classification depending on their morphological, immunohistochemical appearance, and their clinical and molecular characteristics. Objective: To determine the expression of PAX5 in Hodgkin and Non Hodgkin lymphoma and their association with clinical parameters (age & site). Patients & Methods: During a period of 1 year starting from June 2019 to June 2020, 60 lymphoma patients" were included in this"prospective-retrospective"case series study from"medical records and histopathological results in governmental and private labs. Immunohistochemistry examination using PAX5 was performed, and data of the positive PAX5 expression were analyzed. Results: A total of 60 patients were recruited in this study with the majority (58%) were Non Hodgkin lymphoma, dominated by diffuse large B-cell lymphoma subtype (42.8%) and (42%) were Hodgkin lymphoma where nodular sclerosis subtype formed (52%) and mainly of the nodal site in both of them. The age range of Non Hodgkin lymphoma 7-76 years (median 50 years) and 5-67 years (median 21 years) for Hodgkin lymphoma and male predominance in both of them and there is no significant association between the site and lymphoma (p value=0.0647) while a significant association with age (p value =0.037). Moreover, the immunohistochemical examination demonstrates that positive PAX5 was expressed in 77% of Non Hodgkin lymphoma and 100% of Hodgkin lymphoma. The P-value between them was 0.016, which was statistically significant ,no matter of using PAX5 or CD30 in"the diagnosis of Hodgkin lymphoma,in other hand"there is a significant difference between PAX5 and CD3 expression (P value=0.004), while it is not statistically significant when comparing PAX5 and CD20 (P-value =0.317) in the diagnosis of Non Hodgkin lymphoma. Conclusion: This study demonstrates that PAX5 is one of the most sensitive and reliable immunohistochemical marker in diagnosing Hodgkin lymphoma and B-cell Non Hodgkin lymphoma.

Research paper thumbnail of Malaysia’s New Minister of Foreign Affairs A TRIANNUAL PUBLICATION OF THE INSTITUTE OF DIPLOMACY AND FOREIGN RELATIONS, MINISTRY OF FOREIGN AFFAIRS, MALAYSIA

The Honourable Dato’ Saifuddin was Deputy Minister for the Ministry of Higher Education from 2009... more The Honourable Dato’ Saifuddin was Deputy Minister for the Ministry of Higher Education from 2009 to 2013, and Deputy Minister for the Ministry of Entrepreneurship and Cooperative Development from 2008 to 2009. He was also Chief Executive Officer of the Global Movement of Moderates Foundation from 2013 to 2015, and has been Patron to the Malaysian Institute of Debate and Public Speaking since 2013. The Honourable Dato’ Saifuddin is a regular columnist with several newspapers, and has written several books on Malaysian politics, including New Politics 2.0: Multiracial and Moderate Malaysian Democracy (2017).

Research paper thumbnail of The Italian Americans

International Migration Review, 1988

Research paper thumbnail of ASEAN's Political and Security Relations with Japan

A combination of developments is making the current moment particularly propitious for the enhanc... more A combination of developments is making the current moment particularly propitious for the enhancement of political and security cooperation between the Association of Southeast Asian Nations (ASEAN) and Japan-as well as between ASEAN and China and, to a lesser degree, ASEAN and South Korea. If carefully exploited and managed well, the potential for furthering peace, prosperity, and well-being in East Asia will be significant. The focus for cooperation within these relationships, however, will remain primarily in the economic area. This is perhaps just as well, because economic cooperation is both more easily attainable and provides more practical dividends for East Asian well-being than would security cooperation. And economic cooperation prepares the ground for political and security cooperation. It is also consistent with the aspirations of the East Asia Vision 2020, to which all the nations involved subscribe. Factors Driving ASEAN-Japan Political and Security Cooperation ASEAN Countries The relations ASEAN countries have maintained with Japan have for some time been driven essentially by economic considerations, and this is unlikely to change in the future. Interest in Japanese investment (cumulative foreign direct investment amounting to US$544 million in 1990-2001),

Research paper thumbnail of Managing security in Southeast Asia: Existing mechanisms and processes to address regional conflicts

Aust J Int Aff, 1993

History, geostrategic location, geopolitical calculations and the involvement of outside powers h... more History, geostrategic location, geopolitical calculations and the involvement of outside powers have all conspired to foster an extremely disparate set of security mechanisms and processes in Southeast Asia. These range from isolationist neutrality in the case of Myanmar to ...