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Mohamed Saad

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Research paper thumbnail of Coagulation Factor VII R353Q Polymorphism in Patients with Cerebral Venous Thrombosis

Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Background: Although it is relatively uncommon form of stroke, cerebral venous thrombosis (CVT) i... more Background: Although it is relatively uncommon form of stroke, cerebral venous thrombosis (CVT) is still with difficulty in diagnosis and management. There is unsolved debate regarding the association of coagulation factor VII (FVII) R353Q polymorphism with venous thrombosis. Objective: We aimed to assess the association of FVII R353Q polymorphism with the risk of CVT. Methods: Patients with CVT and age and sex-matched controls were included in our study. All patients were subjected to history taking, examination, brain computerized tomography scans (CT), Magnetic resonance imaging (MRI) and magnetic resonance venography (MRV). For patients and controls; assay of FVII levels, and FVII R353Q polymorphism were assessed. Results: A total of 32 patients with CVT and 30 age and sex matched healthy subjects were enrolled in the study. There was no statistically significant difference between patients and controls regarding age, sex, body mass index, laboratory tests. Headache was the comm...

Research paper thumbnail of Clinical and Sonographic Patterns of Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion in Tissue Plasminogen Activator-Treated Patients

Stroke, 2002

Background and Purpose-The National Institutes of Health Stroke Scale (NIHSS) is predictive of th... more Background and Purpose-The National Institutes of Health Stroke Scale (NIHSS) is predictive of thrombus presence but has limited ability to identify occlusion location in the anterior circulation. We describe clinical and sonographic patterns that are associated with tandem internal carotid artery (ICA) and middle cerebral artery (MCA) occlusions.

Research paper thumbnail of Coagulation Factor VII R353Q Polymorphism in Patients with Cerebral Venous Thrombosis

Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Background: Although it is relatively uncommon form of stroke, cerebral venous thrombosis (CVT) i... more Background: Although it is relatively uncommon form of stroke, cerebral venous thrombosis (CVT) is still with difficulty in diagnosis and management. There is unsolved debate regarding the association of coagulation factor VII (FVII) R353Q polymorphism with venous thrombosis. Objective: We aimed to assess the association of FVII R353Q polymorphism with the risk of CVT. Methods: Patients with CVT and age and sex-matched controls were included in our study. All patients were subjected to history taking, examination, brain computerized tomography scans (CT), Magnetic resonance imaging (MRI) and magnetic resonance venography (MRV). For patients and controls; assay of FVII levels, and FVII R353Q polymorphism were assessed. Results: A total of 32 patients with CVT and 30 age and sex matched healthy subjects were enrolled in the study. There was no statistically significant difference between patients and controls regarding age, sex, body mass index, laboratory tests. Headache was the comm...

Research paper thumbnail of Clinical and Sonographic Patterns of Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion in Tissue Plasminogen Activator-Treated Patients

Stroke, 2002

Background and Purpose-The National Institutes of Health Stroke Scale (NIHSS) is predictive of th... more Background and Purpose-The National Institutes of Health Stroke Scale (NIHSS) is predictive of thrombus presence but has limited ability to identify occlusion location in the anterior circulation. We describe clinical and sonographic patterns that are associated with tandem internal carotid artery (ICA) and middle cerebral artery (MCA) occlusions.

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