Mohamed khaled Abdelaziz - Academia.edu (original) (raw)

Papers by Mohamed khaled Abdelaziz

Resumen de la publicación de una participación en formato µVídeo en en el congreso Divulga NextGe... more Resumen de la publicación de una participación en formato µVídeo en en el congreso Divulga NextGen (1ª edición) que se celebrará online, de manera gratuita y en las redes sociales los días 26, 27 y 28 de mayo de 2021.

Frontiers in Plant Science, 2021

Hybrid zones have the potential to shed light on evolutionary processes driving adaptation and sp... more Hybrid zones have the potential to shed light on evolutionary processes driving adaptation and speciation. Secondary contact hybrid zones are particularly powerful natural systems for studying the interaction between divergent genomes to understand the mode and rate at which reproductive isolation accumulates during speciation. We have studied a total of 720 plants belonging to five populations from two Erysimum (Brassicaceae) species presenting a contact zone in the Sierra Nevada mountains (SE Spain). The plants were phenotyped in 2007 and 2017, and most of them were genotyped the first year using 10 microsatellite markers. Plants coming from natural populations were grown in a common garden to evaluate the reproductive barriers between both species by means of controlled crosses. All the plants used for the field and greenhouse study were characterized by measuring traits related to plant size and flower size. We estimated the genetic molecular variances, the genetic differentiati...

SSRN Electronic Journal, 2015

Egypt in the scope of the global energy crisis, which threatens to drain resources from tradition... more Egypt in the scope of the global energy crisis, which threatens to drain resources from traditional energy (non-renewable energy), and it is in a bad need to make energy reduction and to emphasize the sustainability concept.Sustainable architecture, Green architecture and Environmental Architecture all of those trends represents the importance of saving energy consumption through all phases of the Building Life Cycle. This Paper presents an introduction for how to achieve sustainability in construction work, starting from Design decisions (particularly in the selection of building materials and methods of construction) in an attempt to save energy consumption without continuing to drain the surrounding environment.Energy consumption during the construction phase (this phase start from the raw materials used in construction, transporting and Site operating energy until the construction is completed.) represents 40% of the energy of the whole building, and in the absence of a specific method that helps Architects in evaluating the different factors affecting the energy consumption in the construction stage. That can lead to more energy consumption.This Paper aims to achieve the Environmental balance within reducing the Energy Consumption in Construction phase and applying practical actions to reach the sustainability.

Mansoura Journal of Forensic Medicine and Clinical Toxicology, 2007

Gad El-Hak et al ... areas of the world where the prevalence of HBV infection is also high was a ... more Gad El-Hak et al ... areas of the world where the prevalence of HBV infection is also high was a clue to the link between the virus and the tumor (Bosch et al., 2004). HCV cirrhosis increases the risk of HCC dramatically (Di Bisceglie, 1997). It is estimated that between 2 and 5.7 % of all INTRODUCTlON The hepatocellular carcinoma is linked to environmental, dietary and lifestyle factors, so that its incidence and distribution vary widely among ethnic groups, geographical regions and sex. The increased incidence of HCC in

Ecosistemas, 2019

Artículo publicado en Open Access bajo los términos de Creative Commons attribution Non Comercial... more Artículo publicado en Open Access bajo los términos de Creative Commons attribution Non Comercial License 3.0. NOTAS ecosistemas REVISTA CIENTÍFICA DE ECOLOGÍA Y MEDIO AMBIENTE

The American Naturalist, 2018

Self-fertilization has recurrently evolved in plants, involving different strategies and traits a... more Self-fertilization has recurrently evolved in plants, involving different strategies and traits and often loss of attractive functions, collectively known as the selfing syndrome. However, few traits that actively promote self-fertilization have been described. Here we describe a novel mechanism promoting self-fertilization in the Brassicaceae species Erysimum incanum. This mechanism, which we called "anther rubbing," consists of autonomous, repeated, and coordinated movements of the stamens over the stigma during flower opening. We have documented anther rubbing by time-lapse videos and experimentally show that it causes self-pollen deposition on stigmas and is sufficient to achieve maximal reproductive output in E. incanum. We predict that these movements should occur in species with limited inbreeding depression, and indeed we find that inbreeding depression in seed production is negligible in this species. While many studies have documented complex floral traits that promote outcrossing, the occurrence of anther rubbing demonstrates that plants can evolve elaborate and underappreciated adaptations to promote self-fertilization.

International journal of women's health, 2018

Previously, we reported a significantly higher prevalence of uterine fibroids (UFs) in African Am... more Previously, we reported a significantly higher prevalence of uterine fibroids (UFs) in African American women. This minority group also commonly suffers from vitamin D deficiency. We have demonstrated that 1,25(OH)D attains a fibroid growth inhibitory impact through its ability to block the G1/S (gap 1/synthesis) phase of the cell cycle. Vitamin D is involved in DNA damage as well as in immune response regulation, anti-inflammation, autoimmunity and cancer. Since most of the prior data on vitamin D and UF were generated in vitro via established cell lines, it was necessary to verify and validate this observation in vivo using a diet-induced vitamin D-deficient mouse model. Our model of vitamin D lacking function was established using 8-week exposure of C57/BL6 mice to vitamin D-deficient diet provides evidence of different functions accomplished by vitamin D in the regulation of myometrium homeostasis disrupted in the context of uterine fibroid. We found that vitamin D deficiency wa...

Physica B: Condensed Matter, 2010

This article appeared in a journal published by Elsevier. The attached copy is furnished to the a... more This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research and education use, including for instruction at the authors institution and sharing with colleagues. Other uses, including reproduction and distribution, or selling or licensing copies, or posting to personal, institutional or third party websites are prohibited. In most cases authors are permitted to post their version of the article (e.g. in Word or Tex form) to their personal website or institutional repository. Authors requiring further information regarding Elsevier's archiving and manuscript policies are encouraged to visit: http://www.elsevier.com/copyright

Asian Pacific Journal of Cancer Prevention, 2013

Background: Pretreatment serum p53 and epidermal growth factor receptor (EGFR) were assessed usin... more Background: Pretreatment serum p53 and epidermal growth factor receptor (EGFR) were assessed using enzyme-linked immunosorbent assay (ELISA) in patients with acute leukemia to analysis their roles in characterization of different subtypes of the disease. Materials and Methods: Serum samples from thirty two patients with acute myeloid leukemia (AML) and fourteen patients with acute lymphoid leukemia (ALL) were analysed, along with 24 from healthy individuals used as a control group. Results: The results demonstrated a significant increase of serum p53 and EGFR in patients with AML (p<0.0001) compared to the control group. Also, the results showed a significant increase of both markers in patients with ALL (p<0.05, p<0.0001 respectively). Sensitivities and specificities for these variables were 52% and 100% for p53, and 73.9%, 95.8% for EGFR. Serum p53 and EGFR could successfully differentiate between M4 and other AML subtypes, while these variables failed to discriminate among ALL subtypes. A positive significant correlation was noted between p53 and EGFR. Negative significant correlations were observed between these variables and both of hemoglobin (Hg) content and RBC count. Conclusions: Mutant p53 and EGFR are helpful serological markers for diagnosis of patients with AML or ALL and can aid in characterization of disease. Moreover, these markers may reflect carcinogenesis mechanisms.

SAGE Open Medical Case Reports, 2017

Superficial myofibroblastoma of the lower female genital tract is a rare benign, recently recogni... more Superficial myofibroblastoma of the lower female genital tract is a rare benign, recently recognized neoplasm that mostly affects the vulvovaginal area. Our report discusses a case of cervical superficial myofibroblastoma of the lower female genital tract in a 45-year-old patient who is presented with menometrorrhagia. On examination, she had multiple uterine fibroids and a circumscribed submucosal mass lesion involving the anterior lip of cervix. At hysterectomy, histopathological examination of the cervical mass revealed a relatively hypocellular tumor consisted of bland spindled and stellate cells. An immunohistochemistry evaluation revealed reactivity for CD34, desmin, and smooth muscle actin. This neoplasm should be included in the differential diagnosis of cervical mass lesions. This tumor also needs to be differentiated from other mesenchymal lesions of lower female genital tract.

Plant biology (Stuttgart, Germany), Jan 25, 2017

Polyploidization has played an important role in plant diversification, and variation in ploidy l... more Polyploidization has played an important role in plant diversification, and variation in ploidy level may be found not only between species of the same genus, but also within a single species. Although establishing the adaptive significance of polyploidy to explain the geographic distribution of cytotypes is challenging, the occurrence of different cytotypes in different ecological niches may suggest an adaptive role of genome duplication. We have studied the adaptive significance of the geographic distribution of cytotypes across the entire distribution range of the endemic Erysimum mediohispanicum (Brassicaceae). For that, we have used climatic variables, population elevation, and soil properties to model ecological niches for the different cytotypes. In addition, we have analysed the effect that ploidy level has on the floral phenotype. We have found a clear geographic pattern in the distribution of cytotypes, with diploid individuals occurring in the southernmost part of the dis...

Reproductive Sciences, 2017

Introduction: Chemotherapy is the most commonly used modality to treat human cancers; however, in... more Introduction: Chemotherapy is the most commonly used modality to treat human cancers; however, in many cases it causes irreversible ovarian failure. In this work, we plan to evaluate the restorative function of human bone marrow mesenchymal stem cells (BMSCs) in a chemotherapy-induced ovarian failure mouse model. Methods: Acclimatized 4 to 6 week-old female mice (C57BL/6) were assigned randomly to a vehicle-treated control group (group 1), chemotherapy-treated group followed by vehicle alone (group 2), or chemotherapy-treated group followed by stem cell intraovarian injection (group 3). Outcomes were evaluated using immunohistochemistry (IHC), serum hormonal assays, and estrous cycle monitoring and breeding potential. Results: Post BMSCs administration, group 3 promptly showed detectable vaginal smears with estrogenic changes. Increase in total body weight, ovarian weight, and weight of estrogen-responsive organs (uterus and liver) was observed at 2 weeks and continued to end of the experiment. Hematoxylin and Eosin histological evaluation of the ovaries demonstrated a higher mean follicle count in group 3 than in group 2. Group 3 had lower follicle-stimulating hormone (FSH) levels (P ¼ .03) and higher anti-Müllerian hormone serum (AMH) levels (P ¼ .0005) than group 2. The IHC analysis demonstrated higher expression of AMH, FSH receptor, inhibin A, and inhibin B in growing follicles of group 3 versus group 2. Tracking studies demonstrated that human BMSCs evenly repopulated the growing follicles in treated ovaries. Importantly, breeding data showed significant increases in the pregnancies numbers, 2 pregnancies in group 1 and 12 in group 3 (P ¼ .02). Conclusions: Intraovarian administered BMSCs are able to restore ovarian hormone production and reactivate folliculogenesis in chemotherapy-induced ovarian failure mouse model.

Journal of Applied Fluid Mechanics, 2017

Cavitation phenomenon can cause deterioration of the hydraulic performance, damage by pitting, ma... more Cavitation phenomenon can cause deterioration of the hydraulic performance, damage by pitting, material erosion, structure vibration and noise in fluid machinery, turbo-machinery, ship propellers and in many other applications. Therefore, it is important to detect inception of cavitation phenomenon. An experimental study has been carried out in order to investigate the noise radiated by various cavitating sources to determine the validity of noise measurements for detecting the onset of cavitation. Measurements have been made measuring the noise radiated by a number of configurations in a water tunnel at various operating condition to determine the onset of cavitation. The measurements have been conducted over a frequency range of 31.5 Hz to 31.5 kHz in one-third octave bands. The onset of cavitation was measured visually through a Perspex side of the working section of the water tunnel. Moreover, a theoretical estimate of the pressure radiated from the cavitation nuclei at their critical radii and their frequency was presented. Tests indicated that, generally, at the point of visual inception there was a marked rise of the sound pressure level in the high-frequency noise, whilst the low-frequency noise increased as the cavitation developed. This finding was supported by the theoretical estimate of the pulsating frequency of cavitation nuclei. The results illustrated that the visual observations of inception confirm the noise measurements.

Journal of Aquatic Animal Health, 2016

The present study was designed to assess the possible causes of the mass mortalities of Nile Tila... more The present study was designed to assess the possible causes of the mass mortalities of Nile Tilapia Oreochromis niloticus at El-Behera Governorate, Egypt, in relationship to environmental and microbiotic factors. Water samples were collected from fish farms at different locations and from Lake Edku to analyze water temperature, water pH, salinity, biological oxygen demand, dissolved oxygen, total ammonia nitrogen, and un-ionized ammonia. A number of moribund and freshly dead fish were sampled and submitted to our laboratory for microbiological, molecular, and histopathological examination. Water analysis of the fish farms revealed noticeable increases in the previously mentioned physicochemical parameters. Clinical examinations of moribund fish showed severe gill rot and massive external and internal hemorrhages. Ordinary and molecular laboratory findings confirmed the presence of Branchiomyces sp. in gill tissue and mixed bacterial fish pathogens (Streptococcus agalactiae, Vibrio alginolyticus, V. parahaemolyticus, Pseudomonas anguilliseptica, and P. aeruginosa) in visceral organs. The histopathological and transmission electron microscopic examinations revealed severe necrosis of gill filaments and blockage of branchial blood vessels and lamellar capillaries with Branchiomyces sp. hyphae and spores mixed with different shapes of bacteria. Severe inflammations were detected in liver, kidney, heart, and brain tissues. Ultimately, we can conclude that the syndrome of mass fish kills in this area is a consequence of ecological damage to the aquatic environment, which is mainly related to natural and anthropogenic factors, as well as to the presence of infectious agents. Received September 30, 2015; accepted April 12, 2016.

Otolaryngol Head Neck Surg, 2006

Notulae Botanicae Horti Agrobotanici Cluj-napoca, Aug 5, 2007

The performance of compost and microorganisms was compared with standard, commercial rates of NPK... more The performance of compost and microorganisms was compared with standard, commercial rates of NPK fertilizers with respect to the growth, chemical composition and essential oil production of Rosmarinus officinalis L. In two successive seasons, plants treated by a mixture of compost and microorganisms showed a significant increase in vegetative growth, total N, P and carbohydrate content and essential oil production. The findings clearly indicate that compost and microorganisms could replace conventional NPK fertilizers in the cultivation of rosemary, and consequently minimize environmental pollution by these compounds.