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Papers by Mohammed Abdu Elsamea

Research paper thumbnail of Inborn Errors of Immunity among Children with Recurrent Acute Otitis Media

Abstract- und Posterband - 93. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn Interface - Fokus Mensch im Zeitalter der technisierten Medizin

Recurrent acute otitis media (rAOM) may be attributed to environmental, anatomical, and/or geneti... more Recurrent acute otitis media (rAOM) may be attributed to environmental, anatomical, and/or genetic (chromosomal abnormalities-inborn errors of immunity IEIs) factors. 1 Many IEIs patients remain undiagnosed or have a remarkably delayed diagnosis. 2 rAOM is one of the commonest, and occasionally the first, manifestations of IEIs. IEIs may be easily overlooked because rAOM is widespread among otherwise healthy children. 3 In the present study, we investigated the relative frequency, pattern, and associated factors of IEIs among children with rAOM. This could be a place for your table.

Research paper thumbnail of Inborn Errors of Immunity among Egyptian Children with Recurrent Acute Otitis Media

Journal of Pediatric Infectious Diseases

Objective Our objective was to investigate the relative frequency and pattern of inborn errors of... more Objective Our objective was to investigate the relative frequency and pattern of inborn errors of immunity (IEIs) among Egyptian children with recurrent acute otitis media (rAOM). Methods This was a cross-sectional study that included children from the age of 6 months to 16 years with rAOM. Those with structural, functional, and environmental risk factors were excluded. Enrolled children underwent thorough clinical, otorhinolaryngological, and immunological evaluation, including hematological counting, quantitative immunoglobulins assay, lymphocytic flow cytometric immunophenotyping, CH50, and phagocytic function tests. Results The study included 69 children with rAOM (44 boys and 25 girls; median age 30 months). IEIs were identified in 14 children, including transient hypogammaglobulinemia (three cases), selective IgA deficiency (three cases), agammaglobulinemia (two cases), common variable immunodeficiency (two cases), and one case for each of congenital neutropenia, Chediak–Higas...

Research paper thumbnail of Transoral Excision of pre-styloid parapharyngeal space Solitary Fibrous Tumor: A case report and review of the literature

Egyptian Journal of Ear, Nose, Throat and Allied Sciences, 2019

Solitary Fibrous Tumors (SFTs) are relatively rare benign neoplasms that commonly occur in the pl... more Solitary Fibrous Tumors (SFTs) are relatively rare benign neoplasms that commonly occur in the pleura and barely reported in parapharyngeal space. SFT is often misdiagnosed due to its microscopic resemblance to several other spindle cell tumors; however, there are specific diagnostic features on MRI and immunohistochemical.We herein report a case of a 65-year-old male patient with SFT arisen in the parapharyngeal space completely resected through a transoral approach. Also, a comprehensive review of previously published cases and case series of parapharyngeal space SFTs and hemangiopericytoma (HPC) reported globally in English up to August 2018 using the PubMed/Medline databases was presented. In addition to the current case, there are thirteen SFTs and thirteen HPCs reported cases. All cases were presented and analyzed. Males are predominantly affected. Actually, 23% of HPCs reported cases presented with the histological indicator of aggressive behavior while none of SFTs reported ...

Research paper thumbnail of Inborn Errors of Immunity among Children with Recurrent Acute Otitis Media

Abstract- und Posterband - 93. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn Interface - Fokus Mensch im Zeitalter der technisierten Medizin

Recurrent acute otitis media (rAOM) may be attributed to environmental, anatomical, and/or geneti... more Recurrent acute otitis media (rAOM) may be attributed to environmental, anatomical, and/or genetic (chromosomal abnormalities-inborn errors of immunity IEIs) factors. 1 Many IEIs patients remain undiagnosed or have a remarkably delayed diagnosis. 2 rAOM is one of the commonest, and occasionally the first, manifestations of IEIs. IEIs may be easily overlooked because rAOM is widespread among otherwise healthy children. 3 In the present study, we investigated the relative frequency, pattern, and associated factors of IEIs among children with rAOM. This could be a place for your table.

Research paper thumbnail of Inborn Errors of Immunity among Egyptian Children with Recurrent Acute Otitis Media

Journal of Pediatric Infectious Diseases

Objective Our objective was to investigate the relative frequency and pattern of inborn errors of... more Objective Our objective was to investigate the relative frequency and pattern of inborn errors of immunity (IEIs) among Egyptian children with recurrent acute otitis media (rAOM). Methods This was a cross-sectional study that included children from the age of 6 months to 16 years with rAOM. Those with structural, functional, and environmental risk factors were excluded. Enrolled children underwent thorough clinical, otorhinolaryngological, and immunological evaluation, including hematological counting, quantitative immunoglobulins assay, lymphocytic flow cytometric immunophenotyping, CH50, and phagocytic function tests. Results The study included 69 children with rAOM (44 boys and 25 girls; median age 30 months). IEIs were identified in 14 children, including transient hypogammaglobulinemia (three cases), selective IgA deficiency (three cases), agammaglobulinemia (two cases), common variable immunodeficiency (two cases), and one case for each of congenital neutropenia, Chediak–Higas...

Research paper thumbnail of Transoral Excision of pre-styloid parapharyngeal space Solitary Fibrous Tumor: A case report and review of the literature

Egyptian Journal of Ear, Nose, Throat and Allied Sciences, 2019

Solitary Fibrous Tumors (SFTs) are relatively rare benign neoplasms that commonly occur in the pl... more Solitary Fibrous Tumors (SFTs) are relatively rare benign neoplasms that commonly occur in the pleura and barely reported in parapharyngeal space. SFT is often misdiagnosed due to its microscopic resemblance to several other spindle cell tumors; however, there are specific diagnostic features on MRI and immunohistochemical.We herein report a case of a 65-year-old male patient with SFT arisen in the parapharyngeal space completely resected through a transoral approach. Also, a comprehensive review of previously published cases and case series of parapharyngeal space SFTs and hemangiopericytoma (HPC) reported globally in English up to August 2018 using the PubMed/Medline databases was presented. In addition to the current case, there are thirteen SFTs and thirteen HPCs reported cases. All cases were presented and analyzed. Males are predominantly affected. Actually, 23% of HPCs reported cases presented with the histological indicator of aggressive behavior while none of SFTs reported ...