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Papers by Mohammed Abdurrahman
Journal of Clinical Case Reports Medical Images and Health Sciences
Comparative Clinical Pathology
Systemic infammatory response to surgical interventions has been characterized by an orchestrated... more Systemic infammatory response to surgical interventions has been characterized by an orchestrated interplay of endogenous mediatory cytokines and haematologic alterations. The study was carried out to determine the changes in plasma levels of pro-infammatory interleukin-6 (IL-6) and anti-infammatory interleukin-10 (IL-10) in relation to haematological alterations in response to colo-peritoneo-cystoplasty in dogs. Haematological and plasma concentrations of IL-6 and IL-10 were profled in four apparently healthy dogs, following the colo-peritoneo-cystoplastic procedure. Mean packed cell volume (PCV) signifcantly (P<0.05) decreased from the pre-surgical 45.84±3.67 to a lowest value (33.50±2.53%) on day 7 post-surgery. Mean total leukocyte count (TLC) signifcantly (P<0.05) increased from the pre-surgical value (9.85±1.02× 109 /L) to a peak level (14.20±2.77× 109 /L) on day 7 post-surgery. Mean neutrophil count signifcantly (P<0.05) increased from the pre-surgical value of 6.63±0.79 to a peak day 7 post-surgical value (10.00±2.39× 109 /L. Mean lymphocyte count rose from 3.59±0.31 to day 4 post-surgical value of 4.42±0.82× 109 /L. Changes in mean eosinophil and monocyte counts were not signifcant (P>0.05). Mean plasma IL-6 concentration signifcantly (P<0.05) increased from 7639.45±146.81 (presurgical) to 7916.62±32.97 pg/mL on day 4 post-surgery. The pre-surgical mean IL-10 concentration was 93.95±17.18 pg/ mL. It remained relatively unchanged post-surgery until on day 9 when it suddenly surged to 449.70±125.79 pg/mL. The mean concentration of the IL-10 slightly decreased and fuctuates until day 35 when another peak rise (457.20±95.78 pg/ mL) was observed. It was observed that changes in plasma concentrations of IL-6 and IL-10 positively correlated with the leukocytic changes, which suggest presence of a regulatory interplay of IL-6, IL-10 and leukocytic changes in wound healing infammatory response to the colo-peritoneo-cystoplasty in dogs.
Sahel Journal of Veterinary Sciences, 2020
A one-year-old male Terrier dog weighing 22 kg was presented to the Ahmadu Bello University Veter... more A one-year-old male Terrier dog weighing 22 kg was presented to the Ahmadu Bello University Veterinary Teaching Hospital (ABUVTH), Zaria, Nigeria, with complaints of sloughing of the skin and purulent discharges from an injured (sloughed) shoulder. Clinical examination revealed normal vital parameters, extensive necrotized skin on the dorsum extending from loin to the right shoulder and enlarged superficial lymph nodes. Blood and wound swab samples were evaluated in the clinical haematology and Microbiology Laboratories of the ABUVTH, respectively. The Pathology result showed leucocytosis due to neutrophilia and monocytosis. Staphylococcus aureus was isolated from the wound swab. The wound was managed by wet-to-dry bandaging technique using topical antiseptics (Para-chloroaniline solution, chlorhexidine and povidone iodine), improvised non-adhesive protective membrane (polyethylene) applied at the wound-bandage interface, bandages along with adhesive tape and systemic antibiotics. H...
Iranian Journal of Veterinary Surgery, 2021
Cystosonography and cystography are among the appropriate imaging modalities employed in studying... more Cystosonography and cystography are among the appropriate imaging modalities employed in studying the morphological integrity of the urinary bladder in animals. Evaluation of the urinary bladder architecture following autologous composite colo-peritoneal pedicle grafts in the surgical repair of experimental urinary bladder defects was carried out in two dogs. The dorsal aspect of the urinary bladder served as the recipient site, while the seromuscular colonic pedicle flap of the descending colon along with free peritoneal sheath formed a composite tissue (donor tissue). Predetermined 2 cm x 4 cm dimension of urinary bladder defect was created on the dorsum of the urinary bladder and was patched with harvested 3 cm x 5 cm composite colo-peritoneal pedicle flap. All operations were aseptically and humanely conducted. The gross anatomical evaluation of the urinary bladder architecture was performed by ultrasonography and contrast radiography of the repaired urinary bladder. Post-surgic...
Sahel Journal of Veterinary Sciences, 2020
This study was carried out to evaluate the level of asepsis at various stages of the surgical pro... more This study was carried out to evaluate the level of asepsis at various stages of the surgical procedures during the undergraduate students’ wet-lab sessions. Skin and/or wound swabs were collected from different wet lab groups, sessions and stages. The swabs were processed for bacteriological isolation using standard microbiological procedures. A total of 62 isolates of bacteria belonging to 8 genera: Staphylococcus (n=38), Streptococcus (n=1), Corynebacterium n=4), Escherichia (n=7), Proteus (n=8), Klebsiella (n=2), Serratia (n=1) and Acinetobacter (1), were isolated. The most commonly isolated species of bacteria were Staphylococcus equorum (n=31) and Proteus spp. (n=7), which were detected in swabs from ungloved and gloved hands of surgeon and his assistant, patient’s surgical sites and surgical site infections. All the isolates (Gram-positive and negative) were resistant to at least one antibiotic with resistance to the β-lactam antibiotics: ampicillin (89.3% and 100% and amoxic...
Emerging Infectious Diseases, 2020
B ats are vital to many ecosystems and provide benefits to humans (1). However, under certain cir... more B ats are vital to many ecosystems and provide benefits to humans (1). However, under certain circumstances, bats may pose a risk to human health, as they host several zoonotic pathogens (2). Humans should therefore avoid bat contact unless appropriate precautions are taken. Among the most concerning batborne pathogens are viruses within the genus Lyssavirus. Previously unimmunized humans exposed to any of the >16 currently recognized and putative lyssaviruses (typically through a bite from an infected animal) will have 1 of 3 outcomes. First is a complete lack of any lyssavirus infection, characterized by the absence of both illness and lyssavirus-neutralizing antibody production. Second is a productive lyssavirus infection, characterized by a fatal encephalitis known as rabies (3). A human with rabies may produce lyssavirus-neutralizing antibodies in the end stages of illness as the disease progresses, although this response is typically inadequate for viral clearance (4). Third is an abortive lyssavirus infection (sometimes termed an exposure) characterized by the absence of frank encephalitis but with production of lyssavirus-neutralizing antibodies. Although
Journal of Veterinary Advances, 2015
The aim of the study was to determine the correlation between ultrasonographically-measured bipol... more The aim of the study was to determine the correlation between ultrasonographically-measured bipolar length of kidneys with body length and body weight in Yankasa ewes (Ovisaries). A total of 27 apparently healthy ewes weighing between 18-35kg were used for the study. The body lengths of the ewes were measured in inches using a piece of string from the level of the nostrils to the base of the tail. The string was stretched out against a measuring tape and the values obtained were entered into a record book. The paired kidneys of each ewe were scanned in turn through the shaved left paralumbar fossa and the measured bipolar kidney lengths were also recorded. The results obtained showed a positive correlation between the kidney bipolar length and the body length (P<0.05) and a positive correlation between kidney lengths with the body weight the strength of which was lower than that between the kidney length and body length.
A THESIS SUBMITTED TO THE SCHOOL OF POSTGRADUATE STUDIES, AHMADU BELLO UNIVERSITY ZARIA, NIGERIA ... more A THESIS SUBMITTED TO THE SCHOOL OF POSTGRADUATE STUDIES, AHMADU BELLO UNIVERSITY ZARIA, NIGERIA IN PARTIAL FULFILLMENT OF THE REQUIREMENT FOR THE AWARD OF DEGREE OF MASTER OF SCIENCE IN VETERINARY ANAESTHESIA DEPARTMENT OF VETERINARY SURGERY AND RADIOLOGY, AHMADU BELLO UNIVERSITY, ZARIA. MAY, 2014
Diagnostic imaging , 2021
Radiographic and ultrasonographic evaluations of the urinary bladder architecture following autol... more Radiographic and ultrasonographic evaluations of the urinary bladder architecture following autologous composite colo-peritoneal pedicle graft, as alternative tissue for urinary bladder reconstruction, in the surgical repair of experimental urinary bladder defects were carried out in two dogs. Predetermined 2 4 cm dimension of urinary bladder defect was created on the dorsum of the urinary bladder, and was patched with harvested 3 5 cm composite coloperitoneal pedicle flap. All operations were aseptically and humanely conducted. The gross anatomical evaluation of the urinary bladder architecture was performed by ultrasonography and contrast radiography of the repaired urinary bladder. Post-surgical cystosonographic assessments on day 8 showed thickened urinary bladder wall at the point of the graft, which decreased markedly on day 21. Cystographic evaluation revealed gradual transition of the urinary bladder architecture at the point of graft with clear delineation and minimal blurring at week 2 post-operation, which gradually disappeared at weeks 10 and 14. The cystosonographic and cystographic evaluations demonstrated evidence of advanced healing and well-preserved urinary bladder architecture with no evidence of leaks. The imaging modalities are adequately diagnostic to assess urinary bladder repairs following its management with composite colo-peritoneal graft in dogs.
Journal of Clinical Case Reports Medical Images and Health Sciences
Comparative Clinical Pathology
Systemic infammatory response to surgical interventions has been characterized by an orchestrated... more Systemic infammatory response to surgical interventions has been characterized by an orchestrated interplay of endogenous mediatory cytokines and haematologic alterations. The study was carried out to determine the changes in plasma levels of pro-infammatory interleukin-6 (IL-6) and anti-infammatory interleukin-10 (IL-10) in relation to haematological alterations in response to colo-peritoneo-cystoplasty in dogs. Haematological and plasma concentrations of IL-6 and IL-10 were profled in four apparently healthy dogs, following the colo-peritoneo-cystoplastic procedure. Mean packed cell volume (PCV) signifcantly (P<0.05) decreased from the pre-surgical 45.84±3.67 to a lowest value (33.50±2.53%) on day 7 post-surgery. Mean total leukocyte count (TLC) signifcantly (P<0.05) increased from the pre-surgical value (9.85±1.02× 109 /L) to a peak level (14.20±2.77× 109 /L) on day 7 post-surgery. Mean neutrophil count signifcantly (P<0.05) increased from the pre-surgical value of 6.63±0.79 to a peak day 7 post-surgical value (10.00±2.39× 109 /L. Mean lymphocyte count rose from 3.59±0.31 to day 4 post-surgical value of 4.42±0.82× 109 /L. Changes in mean eosinophil and monocyte counts were not signifcant (P>0.05). Mean plasma IL-6 concentration signifcantly (P<0.05) increased from 7639.45±146.81 (presurgical) to 7916.62±32.97 pg/mL on day 4 post-surgery. The pre-surgical mean IL-10 concentration was 93.95±17.18 pg/ mL. It remained relatively unchanged post-surgery until on day 9 when it suddenly surged to 449.70±125.79 pg/mL. The mean concentration of the IL-10 slightly decreased and fuctuates until day 35 when another peak rise (457.20±95.78 pg/ mL) was observed. It was observed that changes in plasma concentrations of IL-6 and IL-10 positively correlated with the leukocytic changes, which suggest presence of a regulatory interplay of IL-6, IL-10 and leukocytic changes in wound healing infammatory response to the colo-peritoneo-cystoplasty in dogs.
Sahel Journal of Veterinary Sciences, 2020
A one-year-old male Terrier dog weighing 22 kg was presented to the Ahmadu Bello University Veter... more A one-year-old male Terrier dog weighing 22 kg was presented to the Ahmadu Bello University Veterinary Teaching Hospital (ABUVTH), Zaria, Nigeria, with complaints of sloughing of the skin and purulent discharges from an injured (sloughed) shoulder. Clinical examination revealed normal vital parameters, extensive necrotized skin on the dorsum extending from loin to the right shoulder and enlarged superficial lymph nodes. Blood and wound swab samples were evaluated in the clinical haematology and Microbiology Laboratories of the ABUVTH, respectively. The Pathology result showed leucocytosis due to neutrophilia and monocytosis. Staphylococcus aureus was isolated from the wound swab. The wound was managed by wet-to-dry bandaging technique using topical antiseptics (Para-chloroaniline solution, chlorhexidine and povidone iodine), improvised non-adhesive protective membrane (polyethylene) applied at the wound-bandage interface, bandages along with adhesive tape and systemic antibiotics. H...
Iranian Journal of Veterinary Surgery, 2021
Cystosonography and cystography are among the appropriate imaging modalities employed in studying... more Cystosonography and cystography are among the appropriate imaging modalities employed in studying the morphological integrity of the urinary bladder in animals. Evaluation of the urinary bladder architecture following autologous composite colo-peritoneal pedicle grafts in the surgical repair of experimental urinary bladder defects was carried out in two dogs. The dorsal aspect of the urinary bladder served as the recipient site, while the seromuscular colonic pedicle flap of the descending colon along with free peritoneal sheath formed a composite tissue (donor tissue). Predetermined 2 cm x 4 cm dimension of urinary bladder defect was created on the dorsum of the urinary bladder and was patched with harvested 3 cm x 5 cm composite colo-peritoneal pedicle flap. All operations were aseptically and humanely conducted. The gross anatomical evaluation of the urinary bladder architecture was performed by ultrasonography and contrast radiography of the repaired urinary bladder. Post-surgic...
Sahel Journal of Veterinary Sciences, 2020
This study was carried out to evaluate the level of asepsis at various stages of the surgical pro... more This study was carried out to evaluate the level of asepsis at various stages of the surgical procedures during the undergraduate students’ wet-lab sessions. Skin and/or wound swabs were collected from different wet lab groups, sessions and stages. The swabs were processed for bacteriological isolation using standard microbiological procedures. A total of 62 isolates of bacteria belonging to 8 genera: Staphylococcus (n=38), Streptococcus (n=1), Corynebacterium n=4), Escherichia (n=7), Proteus (n=8), Klebsiella (n=2), Serratia (n=1) and Acinetobacter (1), were isolated. The most commonly isolated species of bacteria were Staphylococcus equorum (n=31) and Proteus spp. (n=7), which were detected in swabs from ungloved and gloved hands of surgeon and his assistant, patient’s surgical sites and surgical site infections. All the isolates (Gram-positive and negative) were resistant to at least one antibiotic with resistance to the β-lactam antibiotics: ampicillin (89.3% and 100% and amoxic...
Emerging Infectious Diseases, 2020
B ats are vital to many ecosystems and provide benefits to humans (1). However, under certain cir... more B ats are vital to many ecosystems and provide benefits to humans (1). However, under certain circumstances, bats may pose a risk to human health, as they host several zoonotic pathogens (2). Humans should therefore avoid bat contact unless appropriate precautions are taken. Among the most concerning batborne pathogens are viruses within the genus Lyssavirus. Previously unimmunized humans exposed to any of the >16 currently recognized and putative lyssaviruses (typically through a bite from an infected animal) will have 1 of 3 outcomes. First is a complete lack of any lyssavirus infection, characterized by the absence of both illness and lyssavirus-neutralizing antibody production. Second is a productive lyssavirus infection, characterized by a fatal encephalitis known as rabies (3). A human with rabies may produce lyssavirus-neutralizing antibodies in the end stages of illness as the disease progresses, although this response is typically inadequate for viral clearance (4). Third is an abortive lyssavirus infection (sometimes termed an exposure) characterized by the absence of frank encephalitis but with production of lyssavirus-neutralizing antibodies. Although
Journal of Veterinary Advances, 2015
The aim of the study was to determine the correlation between ultrasonographically-measured bipol... more The aim of the study was to determine the correlation between ultrasonographically-measured bipolar length of kidneys with body length and body weight in Yankasa ewes (Ovisaries). A total of 27 apparently healthy ewes weighing between 18-35kg were used for the study. The body lengths of the ewes were measured in inches using a piece of string from the level of the nostrils to the base of the tail. The string was stretched out against a measuring tape and the values obtained were entered into a record book. The paired kidneys of each ewe were scanned in turn through the shaved left paralumbar fossa and the measured bipolar kidney lengths were also recorded. The results obtained showed a positive correlation between the kidney bipolar length and the body length (P<0.05) and a positive correlation between kidney lengths with the body weight the strength of which was lower than that between the kidney length and body length.
A THESIS SUBMITTED TO THE SCHOOL OF POSTGRADUATE STUDIES, AHMADU BELLO UNIVERSITY ZARIA, NIGERIA ... more A THESIS SUBMITTED TO THE SCHOOL OF POSTGRADUATE STUDIES, AHMADU BELLO UNIVERSITY ZARIA, NIGERIA IN PARTIAL FULFILLMENT OF THE REQUIREMENT FOR THE AWARD OF DEGREE OF MASTER OF SCIENCE IN VETERINARY ANAESTHESIA DEPARTMENT OF VETERINARY SURGERY AND RADIOLOGY, AHMADU BELLO UNIVERSITY, ZARIA. MAY, 2014
Diagnostic imaging , 2021
Radiographic and ultrasonographic evaluations of the urinary bladder architecture following autol... more Radiographic and ultrasonographic evaluations of the urinary bladder architecture following autologous composite colo-peritoneal pedicle graft, as alternative tissue for urinary bladder reconstruction, in the surgical repair of experimental urinary bladder defects were carried out in two dogs. Predetermined 2 4 cm dimension of urinary bladder defect was created on the dorsum of the urinary bladder, and was patched with harvested 3 5 cm composite coloperitoneal pedicle flap. All operations were aseptically and humanely conducted. The gross anatomical evaluation of the urinary bladder architecture was performed by ultrasonography and contrast radiography of the repaired urinary bladder. Post-surgical cystosonographic assessments on day 8 showed thickened urinary bladder wall at the point of the graft, which decreased markedly on day 21. Cystographic evaluation revealed gradual transition of the urinary bladder architecture at the point of graft with clear delineation and minimal blurring at week 2 post-operation, which gradually disappeared at weeks 10 and 14. The cystosonographic and cystographic evaluations demonstrated evidence of advanced healing and well-preserved urinary bladder architecture with no evidence of leaks. The imaging modalities are adequately diagnostic to assess urinary bladder repairs following its management with composite colo-peritoneal graft in dogs.