Monica Lujan - Academia.edu (original) (raw)
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UCLA David Geffen School of Medicine
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Papers by Monica Lujan
Journal of Experimental Zoology, 1986
American bullfrogs, Rana catesbeiana respond to prostaglandins with changes in heart rate and blo... more American bullfrogs, Rana catesbeiana respond to prostaglandins with changes in heart rate and blood pressure. These studies compare responses of warm (22°C) and cold acclimated (5°C) bullfrogs to prostaglandins. Gas chromatographic analysis determined equivalent fatty acid profiles in total lipids of heart and artery tissue from warm and cold acclimated animals. Arachidonic acid was the fatty acid precursor found in greatest abundance in both groups. For cardiovascular experiments, bullfrogs were cannulated by using a T-cannula implanted in the right sciatic artery. In warm acclimated bullfrogs, preinfusion systemic arterial pressure (SAP) was 14.7 f 0.5 mm Hg, and heart rate was 33.0 k 1.7 beats/min. Cold acclimated bullfrogs had SAP values of 8.0 & 0.8 mm Hg, and heart rate was 6.9 0.3 beatdmin. Arachidonic and eicosapentaenoic acid infusions (2,000 pgkg body weight [bw]) were hypertensive in cold acclimated and hypotensive in warm acclimated animals.
Journal of Experimental Zoology, 1986
American bullfrogs, Rana catesbeiana respond to prostaglandins with changes in heart rate and blo... more American bullfrogs, Rana catesbeiana respond to prostaglandins with changes in heart rate and blood pressure. These studies compare responses of warm (22°C) and cold acclimated (5°C) bullfrogs to prostaglandins. Gas chromatographic analysis determined equivalent fatty acid profiles in total lipids of heart and artery tissue from warm and cold acclimated animals. Arachidonic acid was the fatty acid precursor found in greatest abundance in both groups. For cardiovascular experiments, bullfrogs were cannulated by using a T-cannula implanted in the right sciatic artery. In warm acclimated bullfrogs, preinfusion systemic arterial pressure (SAP) was 14.7 f 0.5 mm Hg, and heart rate was 33.0 k 1.7 beats/min. Cold acclimated bullfrogs had SAP values of 8.0 & 0.8 mm Hg, and heart rate was 6.9 0.3 beatdmin. Arachidonic and eicosapentaenoic acid infusions (2,000 pgkg body weight [bw]) were hypertensive in cold acclimated and hypotensive in warm acclimated animals.