Monica Tolentino - Academia.edu (original) (raw)
Papers by Monica Tolentino
Diabetology & Metabolic Syndrome, 2015
The study of the conservation status of ornamental stones used in monuments emcompasses a wide va... more The study of the conservation status of ornamental stones used in monuments emcompasses a wide variety of data. Effective control over the decorative stone elements of buildings should be based on mapping their petrographic characteristics, usage, identification of demages and agents of decay they are exposed. This paper analyzes a case study of nineteenth-century building, located in the city of Serro, Minas Gerais, Brazil. This city was an important cultural center and the first city listed by the Brazilian Institute of National Historical and Artistic Heritage in 1938. The building, called Chácara do Barão do Serro, belonged to a dealer in diamonds and features exquisite work in stone. The monitoring of the state of deterioration of the buildings contains georeferenced data and properties from various areas of knowledge, resulting in a complex system. Aiming to ensure accessibility and interpretation of data, a GIS was structured to register mapping and properties of elements. It was intended to show the benefits of using GIS in the control of the deterioration status of the rocks used in monuments and propose methodology to support management of public heritage, which will allow an integrated approach of the characteristics, usage and preservation conditions of the stone elements present in monumental buildings. The use of GIS has given flexibility to diagnose the state of deterioration, which can be used to select aspects that deserve greater attention from public authorities. Further, the presentation of results in maps improves communication between the various sectors involved.
In Bachelard's thought, the understanding "of the other" in scientific thought is given usually b... more In Bachelard's thought, the understanding "of the other" in scientific thought is given usually by means of empirical or rational discourse. However, it is not unusual to realize the emphasis of scientific thought as rationally justifiable.
The study of the conservation status of ornamental stones used in monuments emcompasses a wide va... more The study of the conservation status of ornamental stones used in monuments emcompasses a wide variety of data. Effective control over the decorative stone elements of buildings should be based on mapping their petrographic characteristics, usage, identification of demages and agents of decay they are exposed. This paper analyzes a case study of nineteenth-century building, located in the city of Serro, Minas Gerais, Brazil. This city was an important cultural center and the first city listed by the Brazilian Institute of National Historical and Artistic Heritage in 1938. The building, called Chácara do Barão do Serro, belonged to a dealer in diamonds and features exquisite work in stone. The monitoring of the state of deterioration of the buildings contains georeferenced data and properties from various areas of knowledge, resulting in a complex system. Aiming to ensure accessibility and interpretation of data, a GIS was structured to register mapping and properties of elements. It was intended to show the benefits of using GIS in the control of the deterioration status of the rocks used in monuments and propose methodology to support management of public heritage, which will allow an integrated approach of the characteristics, usage and preservation conditions of the stone elements present in monumental buildings. The use of GIS has given flexibility to diagnose the state of deterioration, which can be used to select aspects that deserve greater attention from public authorities. Further, the presentation of results in maps improves communication between the various sectors involved.
Diabetology & metabolic syndrome, 2014
To evaluate the determinants of intensive insulin regimens (ITs) in patients with type 1 diabetes... more To evaluate the determinants of intensive insulin regimens (ITs) in patients with type 1 diabetes (T1D). This multicenter study was conducted between December 2008 and December 2010 in 28 public clinics in 20 Brazilian cities. Data were obtained from 3,591 patients (56.0% female, 57.1% Caucasian). Insulin regimens were classified as follows: group 1, conventional therapy (CT) (intermediate human insulin, one to two injections daily); group 2 (three or more insulin injections of intermediate plus regular human insulin); group 3 (three or more insulin injections of intermediate human insulin plus short-acting insulin analogues); group 4, basal-bolus (one or two insulin injections of long-acting plus short-acting insulin analogues or regular insulin); and group 5, basal-bolus with continuous subcutaneous insulin infusion (CSII). Groups 2 to 5 were considered IT groups. We obtained complete data from 2,961 patients. Combined intermediate plus regular human insulin was the most used ther...
Diabetology & Metabolic Syndrome, 2015
Archives of Endocrinology and Metabolism, 2015
Objective To evaluate the data of continuous subcutaneous insulin infusion protocol (CSII) for di... more Objective To evaluate the data of continuous subcutaneous insulin infusion protocol (CSII) for diabetics waived by the Health State Secretariat of Distrito Federal (HSSDF) and therapeutic responses three months after the transfer of multiple daily injections regimen for CSII. Subjects and methods Eighty patients (49 female) took part in this experimental study, mean age and disease duration were 27.9 years and 13 years, respectively; 96% patients had type 1 diabetes mellitus. Results The entire sample (ECO) and 3 subgroups (group 1 - A1c decrease, group 2 - A1c stable, and group 3 - A1c increase), stratified according to a ≥ 0.5% change in A1c, were analyzed. Group 1 involved 64% of the patients. The ECO showed a significant A1c decrease: MDI 8.1 ± 1.4% vs. CSII 7.3 ± 0.9%, p < 0.0001 (0.8% difference pro CSII therapy). Group 1 demonstrated an A1c decrease from 8.7% to 7.3% (1.4% difference). Group 2 mean A1c was 7.1%. Rate of hypoglycemia (< 50 mg/dL) decreased 61% in the ECO and 79% in Group 2. Conclusion This study reinforces the safety and efficacy of CSII with a robust A1c reduction and hypoglycemia. The pioneer care HSSDF ambulatory attests to be achievable the free dispensing by Unified Health System (UHS) following a protocol, and this approach results in less wastage to the patient and represents a rational policy of therapy with CSII for UHS. Arch Endocrinol Metab. 2015;59(1):23-8.
Diabetology & metabolic syndrome, 2014
To evaluate the determinants of intensive insulin regimens (ITs) in patients with type 1 diabetes... more To evaluate the determinants of intensive insulin regimens (ITs) in patients with type 1 diabetes (T1D). This multicenter study was conducted between December 2008 and December 2010 in 28 public clinics in 20 Brazilian cities. Data were obtained from 3,591 patients (56.0% female, 57.1% Caucasian). Insulin regimens were classified as follows: group 1, conventional therapy (CT) (intermediate human insulin, one to two injections daily); group 2 (three or more insulin injections of intermediate plus regular human insulin); group 3 (three or more insulin injections of intermediate human insulin plus short-acting insulin analogues); group 4, basal-bolus (one or two insulin injections of long-acting plus short-acting insulin analogues or regular insulin); and group 5, basal-bolus with continuous subcutaneous insulin infusion (CSII). Groups 2 to 5 were considered IT groups. We obtained complete data from 2,961 patients. Combined intermediate plus regular human insulin was the most used ther...
Nutrition Journal, 2014
Background: To determine the relationship between adherence to the diet reported by patients with... more Background: To determine the relationship between adherence to the diet reported by patients with type 1 diabetes under routine clinical care in Brazil, and demographic, socioeconomic status, glycemic control and cardiovascular risk factors. Methods: This was a cross-sectional, multicenter study conducted between Results: Overall, 1,722 (54.2%) of the patients reported to be adherent to the diet without difference in gender, duration of diabetes and socioeconomic status. Patients who reported adherence to the diet had lower BMI, HbA1c, triglycerides, LDL-cholesterol, non HDL-cholesterol and diastolic blood pressure and had more HbA1c at goal, performed more frequently self-monitoring of blood glucose (p < 0.001), and reported less difficulties to follow specific schedules of diet plans (p < 0.001). Less patients who reported to be adherent were obese or overweight (p = 0.005). The quantity of food and time schedule of the meals were the most frequent complaints. Logistic regression analysis showed that ethnicity, (Caucasians,]), number of medical clinical visits in the last year (OR 1.10 [1.06-1.15]), carbohydrate counting, (OR 2.22 [1.49-3.30]) and diets recommended by diabetes societies', (OR 1.57 [1.02-2.41]) were related to greater patients' adherence (p < 0.05) and age, [adolescents (OR 0.60 [0.50-0.72]), high BMI (OR 0.58 [0.94-0.98]) and smoking (OR 0.58 [0.41-0.84]) with poor patients' adherence (p < 0.01).
Diabetology & Metabolic Syndrome, 2012
Background: To determine the relationship between adherence to the diet reported by patients with... more Background: To determine the relationship between adherence to the diet reported by patients with type 1 diabetes under routine clinical care in Brazil, and demographic, socioeconomic status, glycemic control and cardiovascular risk factors. Methods: This was a cross-sectional, multicenter study conducted between Results: Overall, 1,722 (54.2%) of the patients reported to be adherent to the diet without difference in gender, duration of diabetes and socioeconomic status. Patients who reported adherence to the diet had lower BMI, HbA1c, triglycerides, LDL-cholesterol, non HDL-cholesterol and diastolic blood pressure and had more HbA1c at goal, performed more frequently self-monitoring of blood glucose (p < 0.001), and reported less difficulties to follow specific schedules of diet plans (p < 0.001). Less patients who reported to be adherent were obese or overweight (p = 0.005). The quantity of food and time schedule of the meals were the most frequent complaints. Logistic regression analysis showed that ethnicity, (Caucasians,]), number of medical clinical visits in the last year (OR 1.10 [1.06-1.15]), carbohydrate counting, (OR 2.22 [1.49-3.30]) and diets recommended by diabetes societies', (OR 1.57 [1.02-2.41]) were related to greater patients' adherence (p < 0.05) and age, [adolescents (OR 0.60 [0.50-0.72]), high BMI (OR 0.58 [0.94-0.98]) and smoking (OR 0.58 [0.41-0.84]) with poor patients' adherence (p < 0.01).
Diabetology & Metabolic Syndrome, 2015
The study of the conservation status of ornamental stones used in monuments emcompasses a wide va... more The study of the conservation status of ornamental stones used in monuments emcompasses a wide variety of data. Effective control over the decorative stone elements of buildings should be based on mapping their petrographic characteristics, usage, identification of demages and agents of decay they are exposed. This paper analyzes a case study of nineteenth-century building, located in the city of Serro, Minas Gerais, Brazil. This city was an important cultural center and the first city listed by the Brazilian Institute of National Historical and Artistic Heritage in 1938. The building, called Chácara do Barão do Serro, belonged to a dealer in diamonds and features exquisite work in stone. The monitoring of the state of deterioration of the buildings contains georeferenced data and properties from various areas of knowledge, resulting in a complex system. Aiming to ensure accessibility and interpretation of data, a GIS was structured to register mapping and properties of elements. It was intended to show the benefits of using GIS in the control of the deterioration status of the rocks used in monuments and propose methodology to support management of public heritage, which will allow an integrated approach of the characteristics, usage and preservation conditions of the stone elements present in monumental buildings. The use of GIS has given flexibility to diagnose the state of deterioration, which can be used to select aspects that deserve greater attention from public authorities. Further, the presentation of results in maps improves communication between the various sectors involved.
In Bachelard's thought, the understanding "of the other" in scientific thought is given usually b... more In Bachelard's thought, the understanding "of the other" in scientific thought is given usually by means of empirical or rational discourse. However, it is not unusual to realize the emphasis of scientific thought as rationally justifiable.
The study of the conservation status of ornamental stones used in monuments emcompasses a wide va... more The study of the conservation status of ornamental stones used in monuments emcompasses a wide variety of data. Effective control over the decorative stone elements of buildings should be based on mapping their petrographic characteristics, usage, identification of demages and agents of decay they are exposed. This paper analyzes a case study of nineteenth-century building, located in the city of Serro, Minas Gerais, Brazil. This city was an important cultural center and the first city listed by the Brazilian Institute of National Historical and Artistic Heritage in 1938. The building, called Chácara do Barão do Serro, belonged to a dealer in diamonds and features exquisite work in stone. The monitoring of the state of deterioration of the buildings contains georeferenced data and properties from various areas of knowledge, resulting in a complex system. Aiming to ensure accessibility and interpretation of data, a GIS was structured to register mapping and properties of elements. It was intended to show the benefits of using GIS in the control of the deterioration status of the rocks used in monuments and propose methodology to support management of public heritage, which will allow an integrated approach of the characteristics, usage and preservation conditions of the stone elements present in monumental buildings. The use of GIS has given flexibility to diagnose the state of deterioration, which can be used to select aspects that deserve greater attention from public authorities. Further, the presentation of results in maps improves communication between the various sectors involved.
Diabetology & metabolic syndrome, 2014
To evaluate the determinants of intensive insulin regimens (ITs) in patients with type 1 diabetes... more To evaluate the determinants of intensive insulin regimens (ITs) in patients with type 1 diabetes (T1D). This multicenter study was conducted between December 2008 and December 2010 in 28 public clinics in 20 Brazilian cities. Data were obtained from 3,591 patients (56.0% female, 57.1% Caucasian). Insulin regimens were classified as follows: group 1, conventional therapy (CT) (intermediate human insulin, one to two injections daily); group 2 (three or more insulin injections of intermediate plus regular human insulin); group 3 (three or more insulin injections of intermediate human insulin plus short-acting insulin analogues); group 4, basal-bolus (one or two insulin injections of long-acting plus short-acting insulin analogues or regular insulin); and group 5, basal-bolus with continuous subcutaneous insulin infusion (CSII). Groups 2 to 5 were considered IT groups. We obtained complete data from 2,961 patients. Combined intermediate plus regular human insulin was the most used ther...
Diabetology & Metabolic Syndrome, 2015
Archives of Endocrinology and Metabolism, 2015
Objective To evaluate the data of continuous subcutaneous insulin infusion protocol (CSII) for di... more Objective To evaluate the data of continuous subcutaneous insulin infusion protocol (CSII) for diabetics waived by the Health State Secretariat of Distrito Federal (HSSDF) and therapeutic responses three months after the transfer of multiple daily injections regimen for CSII. Subjects and methods Eighty patients (49 female) took part in this experimental study, mean age and disease duration were 27.9 years and 13 years, respectively; 96% patients had type 1 diabetes mellitus. Results The entire sample (ECO) and 3 subgroups (group 1 - A1c decrease, group 2 - A1c stable, and group 3 - A1c increase), stratified according to a ≥ 0.5% change in A1c, were analyzed. Group 1 involved 64% of the patients. The ECO showed a significant A1c decrease: MDI 8.1 ± 1.4% vs. CSII 7.3 ± 0.9%, p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.0001 (0.8% difference pro CSII therapy). Group 1 demonstrated an A1c decrease from 8.7% to 7.3% (1.4% difference). Group 2 mean A1c was 7.1%. Rate of hypoglycemia (&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 50 mg/dL) decreased 61% in the ECO and 79% in Group 2. Conclusion This study reinforces the safety and efficacy of CSII with a robust A1c reduction and hypoglycemia. The pioneer care HSSDF ambulatory attests to be achievable the free dispensing by Unified Health System (UHS) following a protocol, and this approach results in less wastage to the patient and represents a rational policy of therapy with CSII for UHS. Arch Endocrinol Metab. 2015;59(1):23-8.
Diabetology & metabolic syndrome, 2014
To evaluate the determinants of intensive insulin regimens (ITs) in patients with type 1 diabetes... more To evaluate the determinants of intensive insulin regimens (ITs) in patients with type 1 diabetes (T1D). This multicenter study was conducted between December 2008 and December 2010 in 28 public clinics in 20 Brazilian cities. Data were obtained from 3,591 patients (56.0% female, 57.1% Caucasian). Insulin regimens were classified as follows: group 1, conventional therapy (CT) (intermediate human insulin, one to two injections daily); group 2 (three or more insulin injections of intermediate plus regular human insulin); group 3 (three or more insulin injections of intermediate human insulin plus short-acting insulin analogues); group 4, basal-bolus (one or two insulin injections of long-acting plus short-acting insulin analogues or regular insulin); and group 5, basal-bolus with continuous subcutaneous insulin infusion (CSII). Groups 2 to 5 were considered IT groups. We obtained complete data from 2,961 patients. Combined intermediate plus regular human insulin was the most used ther...
Nutrition Journal, 2014
Background: To determine the relationship between adherence to the diet reported by patients with... more Background: To determine the relationship between adherence to the diet reported by patients with type 1 diabetes under routine clinical care in Brazil, and demographic, socioeconomic status, glycemic control and cardiovascular risk factors. Methods: This was a cross-sectional, multicenter study conducted between Results: Overall, 1,722 (54.2%) of the patients reported to be adherent to the diet without difference in gender, duration of diabetes and socioeconomic status. Patients who reported adherence to the diet had lower BMI, HbA1c, triglycerides, LDL-cholesterol, non HDL-cholesterol and diastolic blood pressure and had more HbA1c at goal, performed more frequently self-monitoring of blood glucose (p < 0.001), and reported less difficulties to follow specific schedules of diet plans (p < 0.001). Less patients who reported to be adherent were obese or overweight (p = 0.005). The quantity of food and time schedule of the meals were the most frequent complaints. Logistic regression analysis showed that ethnicity, (Caucasians,]), number of medical clinical visits in the last year (OR 1.10 [1.06-1.15]), carbohydrate counting, (OR 2.22 [1.49-3.30]) and diets recommended by diabetes societies', (OR 1.57 [1.02-2.41]) were related to greater patients' adherence (p < 0.05) and age, [adolescents (OR 0.60 [0.50-0.72]), high BMI (OR 0.58 [0.94-0.98]) and smoking (OR 0.58 [0.41-0.84]) with poor patients' adherence (p < 0.01).
Diabetology & Metabolic Syndrome, 2012
Background: To determine the relationship between adherence to the diet reported by patients with... more Background: To determine the relationship between adherence to the diet reported by patients with type 1 diabetes under routine clinical care in Brazil, and demographic, socioeconomic status, glycemic control and cardiovascular risk factors. Methods: This was a cross-sectional, multicenter study conducted between Results: Overall, 1,722 (54.2%) of the patients reported to be adherent to the diet without difference in gender, duration of diabetes and socioeconomic status. Patients who reported adherence to the diet had lower BMI, HbA1c, triglycerides, LDL-cholesterol, non HDL-cholesterol and diastolic blood pressure and had more HbA1c at goal, performed more frequently self-monitoring of blood glucose (p < 0.001), and reported less difficulties to follow specific schedules of diet plans (p < 0.001). Less patients who reported to be adherent were obese or overweight (p = 0.005). The quantity of food and time schedule of the meals were the most frequent complaints. Logistic regression analysis showed that ethnicity, (Caucasians,]), number of medical clinical visits in the last year (OR 1.10 [1.06-1.15]), carbohydrate counting, (OR 2.22 [1.49-3.30]) and diets recommended by diabetes societies', (OR 1.57 [1.02-2.41]) were related to greater patients' adherence (p < 0.05) and age, [adolescents (OR 0.60 [0.50-0.72]), high BMI (OR 0.58 [0.94-0.98]) and smoking (OR 0.58 [0.41-0.84]) with poor patients' adherence (p < 0.01).