Mark Morasch - Academia.edu (original) (raw)

Papers by Mark Morasch

Atlas of Vascular & Endovascular Surgical Techniques, 2016

Annals of Vascular Surgery, 2003

Annals of vascular surgery, 2009

Carotid artery stenting (CAS) has evolved as a minimally invasive alternative to carotid endarter... more Carotid artery stenting (CAS) has evolved as a minimally invasive alternative to carotid endarterectomy, particularly among patients with prior neck surgery or external beam radiation for malignancy. Restenosis after CAS remains low yet is typically due to neointimal hyperplasia and manifests within the first 2 years after stent placement. We present an unusual case of carotid artery stenosis 18 months after angioplasty and stenting as a result of recurrent malignancy, which was treated with repeat stent placement.

Annals of vascular surgery, 2002

Carotid stenosis is currently estimated using methods based on flow velocity or two-dimensional p... more Carotid stenosis is currently estimated using methods based on flow velocity or two-dimensional projection images. Manipulation of magnetic resonance (MR) images in three dimensions (3-D MR) allows for direct measurement of carotid artery cross-sectional luminal area. The objectives of this study were (1) to assess the accuracy of 3-DMR as a technique for estimating carotid artery stenosis, and (2) to compare 3-D MR results with estimates from duplex ultrasound sonography (DUS) and conventional angiography. Twenty-nine patients underwent rapid, contrast-enhanced MRA within 1 month prior to carotid endarterectomy to obtain 3-D angiographic images of the carotid bifurcation. From these data, post-processing software was used to generate a longitudinal axis through the center of the vessel along which orthogonal cross-sectional images were taken. Luminal area measurements at the location of tightest stenosis and the distal normal internal carotid artery were obtained and used to calcul...

Annals of Vascular Surgery, 1998

Carotid artery resection as part of the management of advanced head and neck cancers remains cont... more Carotid artery resection as part of the management of advanced head and neck cancers remains controversial. Since 1991, 30 patients have undergone resection of the carotid artery with immediate reconstruction using superficial femoral artery as replacement conduit. There was one stroke/death. Forty-three percent developed neck wound problems but no grafts failed or hemorrhaged. Mean follow-up was 20 months (3-76) and mean life expectancy was 16 months from the time of surgery. Fifty-eight percent were free of local recurrence at the time of death. There was a 35% disease-free survival rate at 2 years. These results compare favorably with alternative therapy including carotid ligation or shaving tumor from the carotid artery. Given the importance of cerebral perfusion and local tumor control we offer superficial femoral artery as a durable conduit for immediate extracranial carotid reconstruction in the often hostile environment associated with cancer resection in the neck.

Vascular and Endovascular Surgery, 2002

The most prevalent lesion of the vertebral artery is an atheromatous plaque located at its origin... more The most prevalent lesion of the vertebral artery is an atheromatous plaque located at its origin from the subclavian artery. A case of successful management of a symptomatic vertebral artery aneurysm due to Ehlers-Danlos syndrome is reported. The patient had asymptomatic posterior intracerebral artery dissection on the contralateral side. A common carotid artery to V-3 segment bypass using reversed saphenous vein graft was carried out. Avulsion of the V-2 segment occurred peroperatively and endovascular coil embolization of the vertebral artery aneurysm was performed. Endovascular equipment and training must be in the armamentarium of vascular surgeons as more complex cases are being treated, which demands new approaches for ultimate clinical success. This unique case outlines what might unexpectedly occur. Endovascular intervention as an adjuvant procedure provides a satisfactory outcome in what could have been a catastrophe.

Annals of Vascular Surgery, 2003

Endovascular Interventions, 2013

ABSTRACT Aortic dissections result from a dynamic tear in the aortic wall allowing arterial blood... more ABSTRACT Aortic dissections result from a dynamic tear in the aortic wall allowing arterial blood flow to penetrate between the intima and media layers. This classically results in a false and true lumen and can form a plane antegrade, retrograde, or in combination. In the acute phase, the dissection flap appears friable, thin, and curvilinear on imaging. Chronicity can be determined with the flap appearing thick and straight. Dissections have been classified based on the location of the intimal tear by two separate systems. The DeBakey classification separates dissections into three types: Type 1 involves the ascending aorta as well as the descending portion. Type II involves only the ascending aorta. Type IIIa involves only the descending aorta. Type IIIb involves the descending and abdominal aorta and at times extends into the iliac system. The Stanford classification, more commonly utilized, has two types. Type A involves the ascending aorta and/or descending aorta. Type B involves only the descending aorta and spares the ascending and arch aorta.

Annals of Vascular Surgery, 2005

With smaller access sheath sizes and with the development of suture-mediated arterial closure dev... more With smaller access sheath sizes and with the development of suture-mediated arterial closure devices, completely percutaneous treatment of abdominal and thoracic aneurysms with local anesthesia is now feasible. Potential advantages to percutaneous endograft deployment include shorter procedure time, improved patient acceptance, earlier ambulation, and reduced risk for wound complication~.~-' However, percutaneous sheath placement has its own unique set of risks, and practitioners must be comfortable with the techniques in order for the benefits to outweigh these risks. This technique requires familiarity with off-label use of suture-mediated closure devices, and percutaneous approaches are facilitated by the use of endografts that can be deployed with short procedure times and through relatively small introducer sheaths.'

Surgery, 2011

Despite advances in endoluminal salvage for failed endografts, certain circumstances necessitate ... more Despite advances in endoluminal salvage for failed endografts, certain circumstances necessitate open endovascular abdominal aneurysm repair (EVAR) conversion. We review the indications for and outcomes after late EVAR explants. Retrospective review of EVAR patients requiring delayed (>30 days) conversion from 1999 to 2009. Demographics, index endovascular procedure, conversion indication/technique, and outcomes were analyzed. Among 16 patients who required late conversion, the mean age was 73 years (range, 41-84 years) and 94% were men. Indications included 9 device failures, 6 endograft infections, and a single type II endoleak with sac enlargement. Explanted prostheses included the following: 7 Cook Zenith(®) endoprosthesis, 3 Gore Excluder(®) grafts, 3 Medtronic AneuRx(®) endograft devices, 2 Endologix Powerlink(®) endografts, and 1 Guidant Ancure(®) graft. Before conversion, 7 patients underwent unsuccessful secondary salvage procedures. Transperitoneal (81%) and left retroperitoneal approaches (19%) were used, with 75% requiring supraceliac control. Reconstructions depended on clinical manifestations and included 10 in situ prosthetic repairs, 4 extra-anatomic bypasses, and 2 in situ cryopreserved human allograft repairs. Two patients died during their hospitalization, resulting in a 13% mortality rate. Mean hospitalization for survivors was 18 days (range, 6-78 days), and 7 (50%) of the patients were discharged directly home. Most delayed EVAR conversions are because of device failure or infection and can be successfully converted to open surgical reconstruction. Supraceliac control is often required, and the perioperative complications are greater than primary elective open or endovascular repair. This study addresses how best to manage failed abdominal aortic endografts and what can be done to improve patient outcomes with this difficult clinical problem.

Journal of Vascular Surgery, 2014

Annals of Vascular Surgery, 2009

Annals of Vascular Surgery, 2013

Extracranial vertebral artery aneurysms are uncommon and are usually associated with trauma or di... more Extracranial vertebral artery aneurysms are uncommon and are usually associated with trauma or dissection. Primary cervical vertebral aneurysms are even rarer and are not well described. The presentation and natural history are unknown and operative management can be difficult. Accessing aneurysms at the skull base can be difficult and, because the frail arteries are often afflicted with connective tissue abnormalities, direct repair can be particularly challenging. We describe the presentation and surgical management of patients with primary extracranial vertebral artery aneurysms. In this study we performed a retrospective, multi-institutional review of patients with primary aneurysms within the extracranial vertebral artery. Between January 2000 and January 2011, 7 patients, aged 12-56 years, were noted to have 9 primary extracranial vertebral artery aneurysms. All had underlying connective tissue or another hereditary disorder, including Ehler-Danlos syndrome (n=3), Marfan's disease (n=2), neurofibromatosis (n=1), and an unspecified connective tissue abnormality (n=1). Eight of 9 aneurysms were managed operatively, including an attempted bypass that ultimately required vertebral ligation; the contralateral aneurysm on this patient has not been treated. Open interventions included vertebral bypass with vein, external carotid autograft, and vertebral transposition to the internal carotid artery. Special techniques were used for handling the anastomoses in patients with Ehler-Danlos syndrome. Although endovascular exclusion was not performed in isolation, 2 hybrid procedures were performed. There were no instances of perioperative stroke or death. Primary extracranial vertebral artery aneurysms are rare and occur in patients with hereditary disorders. Operative intervention is warranted in symptomatic patients. Exclusion and reconstruction may be performed with open and hybrid techniques with low morbidity and mortality.

Surgery, 2005

Venous thromboembolism (VTE), manifest as deep venous thrombosis (DVT) or pulmonary embolus, rema... more Venous thromboembolism (VTE), manifest as deep venous thrombosis (DVT) or pulmonary embolus, remains an important complication in bariatric operation patients. Our purpose was to determine the incidence of VTE in a consecutive series of patients undergoing Roux-en-Y gastric bypass (RYGB) to guide appropriate therapy. We prospectively examined a consecutive series of RYGB patients with bilateral lower-extremity venous duplex scan (DS) preoperatively, on postoperative day (POD)#2, and approximately POD#14. Preoperative clinical information including history of VTE, intraoperative data, postoperative course, and complications were recorded. Heparin 5,000 U subcutaneously was administered before the operation and every 12 hours throughout hospitalization along with sequential compression devices. Ambulation was instituted on POD#1. Temporary caval filters were placed in patients with a history of VTE. A total of 106 patients were examined. Body mass index was 51 +/- 8 kg/m2 (range, 40-73 kg/m2). Laparoscopic RYGB was performed in 75%. Hospital length of stay was 2.5 +/- 0.6 days. One hundred patients had no history of VTE; none had a positive DS preoperatively or on POD#2. One patient had a positive POD#14 DS and a second patient had a superficial thrombophlebitis, but a negative DS for DVT (both patients were symptomatic). Six patients had a prior history of VTE; all underwent preoperative placement of a temporary caval filter. Of these 6 patients, 1 developed a new postoperative DVT and another patient had thrombus on the caval filter with a negative lower-extremity DS. Occult DVT was not observed preoperatively in RYGB patients, suggesting that routine preoperative DS is not necessary in the absence of VTE history. Prophylaxis of heparin and sequential compression devices appears satisfactory in preventing DVT with only a 1% incidence in patients with no prior history of VTE. Two of the 6 patients with prior history of VTE showed evidence of thrombus postoperatively. Although a small number of patients, this finding suggests that a caval filter should be placed preoperatively in RYGB patients with a history of VTE.

Surgery, 2005

Open repair of thoracic aortic aneurysms (TAAs) is fraught with high morbidity and mortality rate... more Open repair of thoracic aortic aneurysms (TAAs) is fraught with high morbidity and mortality rates. The availability of endoprostheses for treating thoracic aortic pathology has not kept pace with those for treating abdominal aneurysms. Technical feasibility, durability, and safety of custom-made stent-grafts for the treatment of TAAs and dissections are evaluated. From July 2002 to October 2004 there were 15 patients with TAAs, intramural hematoma, or dissections treated with custom-made endografts. Grafts were deployed after brief adenosine-induced cardiac arrest. Computed tomography scans were obtained 1 month postoperatively and every 6 months thereafter. The mean follow-up period was 15 months (range, 3-31 mo). The mean age of patients was 67 +/- 11 years (range, 47-81 y; 67% men, 33% women). Indications for repair included TAA (10), chronic type B dissection (3), penetrating ulcer (1), and acute dissection (1). Planned concomitant procedures included subclavian-carotid transposition (2) and aortosplenic bypass (2) to achieve adequate proximal or distal landing seal zones, respectively. The mean length of hospital stay was 8 days (range, 1-49 d). Immediate complications included 2 access-related events, 1 cerebellar infarction treated expectantly, and 1 death from a large hemispheric stroke. There were no cases of postoperative paralysis and on follow-up imaging no cases of endoleak, endograft migration, or stent fractures were found. No late deaths occurred caused by stent-graft repair or aneurysm-related causes. Endoluminal exclusion of thoracic aortic aneurysms and dissections can be achieved successfully using custom-made stent-grafts. The use of specially designed devices appears to be technically feasible and durable, with acceptable morbidity and mortality rates.

Radiology, 2007

This HIPAA-compliant study had institutional review board approval. Informed consent was obtained... more This HIPAA-compliant study had institutional review board approval. Informed consent was obtained. The purpose was to prospectively evaluate a segmented three-dimensional (3D) double inversion recovery (DIR)-prepared steady-state free precession (SSFP) magnetic resonance (MR) imaging sequence for fast high-spatial-resolution black-blood carotid arterial wall imaging. Carotid wall-lumen contrast-to-noise ratio (CNR) obtained with this sequence was compared with those obtained with two-dimensional (2D) single- and multisection black-blood fast spin-echo (SE) sequences. MR imaging of both carotid artery bifurcations over 3 cm of transverse coverage was performed in eight volunteers (seven men, one woman; age range, 26-56 years) with no known history of carotid artery disease. Adjusted for section thickness and imaging time per section, higher effective mean CNR was achieved with segmented 3D DIR-prepared SSFP than with single-section 2D DIR-prepared fast SE or multisection 2D saturation-band fast SE (P < .05). Segmented 3D DIR-prepared SSFP enables black-blood carotid arterial wall MR imaging with contiguous thin-section coverage and greater imaging speed and effective CNR than conventional 2D fast SE techniques.

Journal of Magnetic Resonance Imaging, 2006

Spine, 2012

Study Design. A retrospective data analysisObjective. To report a comprehensive assessment of pre... more Study Design. A retrospective data analysisObjective. To report a comprehensive assessment of preoperative prophylactic inferior vena cava filter placement (IVCf) in spine surgery.Summary of Background Data. Venous thromboembolism (VTE) is a serious complication following major spinal reconstructive surgery in adults. Specifically, pulmonary embolism (PE) can result in significant morbidity and mortality, and has been reported in up to 13% of patients. Prophylactic IVCf placement was initiated for all "high-risk" spine patients after a pilot study demonstrated decreased VTE-related morbidity and mortality.Methods. With IRB approval, the medical records of all patients receiving an IVCf at a single institution were reviewed from 2000 to 2007. Age, sex, surgical approach, postoperative deep vein thrombosis (DVT), postoperative superficial thrombus, presence of PE or paradoxical embolus, mortality, and IVCf complications were all evaluated. Indications for IVCf placement incl...

CardioVascular and Interventional Radiology, 2010

Annual Review of Medicine, 2000

▪ Lower-extremity vascular surgery is most often indicated for patients with critical leg ische... more ▪ Lower-extremity vascular surgery is most often indicated for patients with critical leg ischemia but has increasingly been used for patients with disabling intermittent claudication. This article reviews indications, follow-up protocols, and procedure-related outcomes including perioperative and late mortality, complications, and long-term patency rates, which vary with patient risk factors, vascular disease severity, and hospital volume. Population-based studies have yet to establish whether rates of limb-preserving bypass surgery are related to overall amputation rates, partly because of the continued high rate of primary amputation. The functional benefits of vascular surgery have been traditionally assessed by treadmill protocols and batteries of physical tests. Claudication treatment is increasingly being measured by both generic and disease-specific functional and health-related quality-of-life questionnaires. Patient self-reported measures of physical functioning and walk...

Atlas of Vascular & Endovascular Surgical Techniques, 2016

Annals of Vascular Surgery, 2003

Annals of vascular surgery, 2009

Carotid artery stenting (CAS) has evolved as a minimally invasive alternative to carotid endarter... more Carotid artery stenting (CAS) has evolved as a minimally invasive alternative to carotid endarterectomy, particularly among patients with prior neck surgery or external beam radiation for malignancy. Restenosis after CAS remains low yet is typically due to neointimal hyperplasia and manifests within the first 2 years after stent placement. We present an unusual case of carotid artery stenosis 18 months after angioplasty and stenting as a result of recurrent malignancy, which was treated with repeat stent placement.

Annals of vascular surgery, 2002

Carotid stenosis is currently estimated using methods based on flow velocity or two-dimensional p... more Carotid stenosis is currently estimated using methods based on flow velocity or two-dimensional projection images. Manipulation of magnetic resonance (MR) images in three dimensions (3-D MR) allows for direct measurement of carotid artery cross-sectional luminal area. The objectives of this study were (1) to assess the accuracy of 3-DMR as a technique for estimating carotid artery stenosis, and (2) to compare 3-D MR results with estimates from duplex ultrasound sonography (DUS) and conventional angiography. Twenty-nine patients underwent rapid, contrast-enhanced MRA within 1 month prior to carotid endarterectomy to obtain 3-D angiographic images of the carotid bifurcation. From these data, post-processing software was used to generate a longitudinal axis through the center of the vessel along which orthogonal cross-sectional images were taken. Luminal area measurements at the location of tightest stenosis and the distal normal internal carotid artery were obtained and used to calcul...

Annals of Vascular Surgery, 1998

Carotid artery resection as part of the management of advanced head and neck cancers remains cont... more Carotid artery resection as part of the management of advanced head and neck cancers remains controversial. Since 1991, 30 patients have undergone resection of the carotid artery with immediate reconstruction using superficial femoral artery as replacement conduit. There was one stroke/death. Forty-three percent developed neck wound problems but no grafts failed or hemorrhaged. Mean follow-up was 20 months (3-76) and mean life expectancy was 16 months from the time of surgery. Fifty-eight percent were free of local recurrence at the time of death. There was a 35% disease-free survival rate at 2 years. These results compare favorably with alternative therapy including carotid ligation or shaving tumor from the carotid artery. Given the importance of cerebral perfusion and local tumor control we offer superficial femoral artery as a durable conduit for immediate extracranial carotid reconstruction in the often hostile environment associated with cancer resection in the neck.

Vascular and Endovascular Surgery, 2002

The most prevalent lesion of the vertebral artery is an atheromatous plaque located at its origin... more The most prevalent lesion of the vertebral artery is an atheromatous plaque located at its origin from the subclavian artery. A case of successful management of a symptomatic vertebral artery aneurysm due to Ehlers-Danlos syndrome is reported. The patient had asymptomatic posterior intracerebral artery dissection on the contralateral side. A common carotid artery to V-3 segment bypass using reversed saphenous vein graft was carried out. Avulsion of the V-2 segment occurred peroperatively and endovascular coil embolization of the vertebral artery aneurysm was performed. Endovascular equipment and training must be in the armamentarium of vascular surgeons as more complex cases are being treated, which demands new approaches for ultimate clinical success. This unique case outlines what might unexpectedly occur. Endovascular intervention as an adjuvant procedure provides a satisfactory outcome in what could have been a catastrophe.

Annals of Vascular Surgery, 2003

Endovascular Interventions, 2013

ABSTRACT Aortic dissections result from a dynamic tear in the aortic wall allowing arterial blood... more ABSTRACT Aortic dissections result from a dynamic tear in the aortic wall allowing arterial blood flow to penetrate between the intima and media layers. This classically results in a false and true lumen and can form a plane antegrade, retrograde, or in combination. In the acute phase, the dissection flap appears friable, thin, and curvilinear on imaging. Chronicity can be determined with the flap appearing thick and straight. Dissections have been classified based on the location of the intimal tear by two separate systems. The DeBakey classification separates dissections into three types: Type 1 involves the ascending aorta as well as the descending portion. Type II involves only the ascending aorta. Type IIIa involves only the descending aorta. Type IIIb involves the descending and abdominal aorta and at times extends into the iliac system. The Stanford classification, more commonly utilized, has two types. Type A involves the ascending aorta and/or descending aorta. Type B involves only the descending aorta and spares the ascending and arch aorta.

Annals of Vascular Surgery, 2005

With smaller access sheath sizes and with the development of suture-mediated arterial closure dev... more With smaller access sheath sizes and with the development of suture-mediated arterial closure devices, completely percutaneous treatment of abdominal and thoracic aneurysms with local anesthesia is now feasible. Potential advantages to percutaneous endograft deployment include shorter procedure time, improved patient acceptance, earlier ambulation, and reduced risk for wound complication~.~-' However, percutaneous sheath placement has its own unique set of risks, and practitioners must be comfortable with the techniques in order for the benefits to outweigh these risks. This technique requires familiarity with off-label use of suture-mediated closure devices, and percutaneous approaches are facilitated by the use of endografts that can be deployed with short procedure times and through relatively small introducer sheaths.'

Surgery, 2011

Despite advances in endoluminal salvage for failed endografts, certain circumstances necessitate ... more Despite advances in endoluminal salvage for failed endografts, certain circumstances necessitate open endovascular abdominal aneurysm repair (EVAR) conversion. We review the indications for and outcomes after late EVAR explants. Retrospective review of EVAR patients requiring delayed (>30 days) conversion from 1999 to 2009. Demographics, index endovascular procedure, conversion indication/technique, and outcomes were analyzed. Among 16 patients who required late conversion, the mean age was 73 years (range, 41-84 years) and 94% were men. Indications included 9 device failures, 6 endograft infections, and a single type II endoleak with sac enlargement. Explanted prostheses included the following: 7 Cook Zenith(®) endoprosthesis, 3 Gore Excluder(®) grafts, 3 Medtronic AneuRx(®) endograft devices, 2 Endologix Powerlink(®) endografts, and 1 Guidant Ancure(®) graft. Before conversion, 7 patients underwent unsuccessful secondary salvage procedures. Transperitoneal (81%) and left retroperitoneal approaches (19%) were used, with 75% requiring supraceliac control. Reconstructions depended on clinical manifestations and included 10 in situ prosthetic repairs, 4 extra-anatomic bypasses, and 2 in situ cryopreserved human allograft repairs. Two patients died during their hospitalization, resulting in a 13% mortality rate. Mean hospitalization for survivors was 18 days (range, 6-78 days), and 7 (50%) of the patients were discharged directly home. Most delayed EVAR conversions are because of device failure or infection and can be successfully converted to open surgical reconstruction. Supraceliac control is often required, and the perioperative complications are greater than primary elective open or endovascular repair. This study addresses how best to manage failed abdominal aortic endografts and what can be done to improve patient outcomes with this difficult clinical problem.

Journal of Vascular Surgery, 2014

Annals of Vascular Surgery, 2009

Annals of Vascular Surgery, 2013

Extracranial vertebral artery aneurysms are uncommon and are usually associated with trauma or di... more Extracranial vertebral artery aneurysms are uncommon and are usually associated with trauma or dissection. Primary cervical vertebral aneurysms are even rarer and are not well described. The presentation and natural history are unknown and operative management can be difficult. Accessing aneurysms at the skull base can be difficult and, because the frail arteries are often afflicted with connective tissue abnormalities, direct repair can be particularly challenging. We describe the presentation and surgical management of patients with primary extracranial vertebral artery aneurysms. In this study we performed a retrospective, multi-institutional review of patients with primary aneurysms within the extracranial vertebral artery. Between January 2000 and January 2011, 7 patients, aged 12-56 years, were noted to have 9 primary extracranial vertebral artery aneurysms. All had underlying connective tissue or another hereditary disorder, including Ehler-Danlos syndrome (n=3), Marfan's disease (n=2), neurofibromatosis (n=1), and an unspecified connective tissue abnormality (n=1). Eight of 9 aneurysms were managed operatively, including an attempted bypass that ultimately required vertebral ligation; the contralateral aneurysm on this patient has not been treated. Open interventions included vertebral bypass with vein, external carotid autograft, and vertebral transposition to the internal carotid artery. Special techniques were used for handling the anastomoses in patients with Ehler-Danlos syndrome. Although endovascular exclusion was not performed in isolation, 2 hybrid procedures were performed. There were no instances of perioperative stroke or death. Primary extracranial vertebral artery aneurysms are rare and occur in patients with hereditary disorders. Operative intervention is warranted in symptomatic patients. Exclusion and reconstruction may be performed with open and hybrid techniques with low morbidity and mortality.

Surgery, 2005

Venous thromboembolism (VTE), manifest as deep venous thrombosis (DVT) or pulmonary embolus, rema... more Venous thromboembolism (VTE), manifest as deep venous thrombosis (DVT) or pulmonary embolus, remains an important complication in bariatric operation patients. Our purpose was to determine the incidence of VTE in a consecutive series of patients undergoing Roux-en-Y gastric bypass (RYGB) to guide appropriate therapy. We prospectively examined a consecutive series of RYGB patients with bilateral lower-extremity venous duplex scan (DS) preoperatively, on postoperative day (POD)#2, and approximately POD#14. Preoperative clinical information including history of VTE, intraoperative data, postoperative course, and complications were recorded. Heparin 5,000 U subcutaneously was administered before the operation and every 12 hours throughout hospitalization along with sequential compression devices. Ambulation was instituted on POD#1. Temporary caval filters were placed in patients with a history of VTE. A total of 106 patients were examined. Body mass index was 51 +/- 8 kg/m2 (range, 40-73 kg/m2). Laparoscopic RYGB was performed in 75%. Hospital length of stay was 2.5 +/- 0.6 days. One hundred patients had no history of VTE; none had a positive DS preoperatively or on POD#2. One patient had a positive POD#14 DS and a second patient had a superficial thrombophlebitis, but a negative DS for DVT (both patients were symptomatic). Six patients had a prior history of VTE; all underwent preoperative placement of a temporary caval filter. Of these 6 patients, 1 developed a new postoperative DVT and another patient had thrombus on the caval filter with a negative lower-extremity DS. Occult DVT was not observed preoperatively in RYGB patients, suggesting that routine preoperative DS is not necessary in the absence of VTE history. Prophylaxis of heparin and sequential compression devices appears satisfactory in preventing DVT with only a 1% incidence in patients with no prior history of VTE. Two of the 6 patients with prior history of VTE showed evidence of thrombus postoperatively. Although a small number of patients, this finding suggests that a caval filter should be placed preoperatively in RYGB patients with a history of VTE.

Surgery, 2005

Open repair of thoracic aortic aneurysms (TAAs) is fraught with high morbidity and mortality rate... more Open repair of thoracic aortic aneurysms (TAAs) is fraught with high morbidity and mortality rates. The availability of endoprostheses for treating thoracic aortic pathology has not kept pace with those for treating abdominal aneurysms. Technical feasibility, durability, and safety of custom-made stent-grafts for the treatment of TAAs and dissections are evaluated. From July 2002 to October 2004 there were 15 patients with TAAs, intramural hematoma, or dissections treated with custom-made endografts. Grafts were deployed after brief adenosine-induced cardiac arrest. Computed tomography scans were obtained 1 month postoperatively and every 6 months thereafter. The mean follow-up period was 15 months (range, 3-31 mo). The mean age of patients was 67 +/- 11 years (range, 47-81 y; 67% men, 33% women). Indications for repair included TAA (10), chronic type B dissection (3), penetrating ulcer (1), and acute dissection (1). Planned concomitant procedures included subclavian-carotid transposition (2) and aortosplenic bypass (2) to achieve adequate proximal or distal landing seal zones, respectively. The mean length of hospital stay was 8 days (range, 1-49 d). Immediate complications included 2 access-related events, 1 cerebellar infarction treated expectantly, and 1 death from a large hemispheric stroke. There were no cases of postoperative paralysis and on follow-up imaging no cases of endoleak, endograft migration, or stent fractures were found. No late deaths occurred caused by stent-graft repair or aneurysm-related causes. Endoluminal exclusion of thoracic aortic aneurysms and dissections can be achieved successfully using custom-made stent-grafts. The use of specially designed devices appears to be technically feasible and durable, with acceptable morbidity and mortality rates.

Radiology, 2007

This HIPAA-compliant study had institutional review board approval. Informed consent was obtained... more This HIPAA-compliant study had institutional review board approval. Informed consent was obtained. The purpose was to prospectively evaluate a segmented three-dimensional (3D) double inversion recovery (DIR)-prepared steady-state free precession (SSFP) magnetic resonance (MR) imaging sequence for fast high-spatial-resolution black-blood carotid arterial wall imaging. Carotid wall-lumen contrast-to-noise ratio (CNR) obtained with this sequence was compared with those obtained with two-dimensional (2D) single- and multisection black-blood fast spin-echo (SE) sequences. MR imaging of both carotid artery bifurcations over 3 cm of transverse coverage was performed in eight volunteers (seven men, one woman; age range, 26-56 years) with no known history of carotid artery disease. Adjusted for section thickness and imaging time per section, higher effective mean CNR was achieved with segmented 3D DIR-prepared SSFP than with single-section 2D DIR-prepared fast SE or multisection 2D saturation-band fast SE (P < .05). Segmented 3D DIR-prepared SSFP enables black-blood carotid arterial wall MR imaging with contiguous thin-section coverage and greater imaging speed and effective CNR than conventional 2D fast SE techniques.

Journal of Magnetic Resonance Imaging, 2006

Spine, 2012

Study Design. A retrospective data analysisObjective. To report a comprehensive assessment of pre... more Study Design. A retrospective data analysisObjective. To report a comprehensive assessment of preoperative prophylactic inferior vena cava filter placement (IVCf) in spine surgery.Summary of Background Data. Venous thromboembolism (VTE) is a serious complication following major spinal reconstructive surgery in adults. Specifically, pulmonary embolism (PE) can result in significant morbidity and mortality, and has been reported in up to 13% of patients. Prophylactic IVCf placement was initiated for all "high-risk" spine patients after a pilot study demonstrated decreased VTE-related morbidity and mortality.Methods. With IRB approval, the medical records of all patients receiving an IVCf at a single institution were reviewed from 2000 to 2007. Age, sex, surgical approach, postoperative deep vein thrombosis (DVT), postoperative superficial thrombus, presence of PE or paradoxical embolus, mortality, and IVCf complications were all evaluated. Indications for IVCf placement incl...

CardioVascular and Interventional Radiology, 2010

Annual Review of Medicine, 2000

▪ Lower-extremity vascular surgery is most often indicated for patients with critical leg ische... more ▪ Lower-extremity vascular surgery is most often indicated for patients with critical leg ischemia but has increasingly been used for patients with disabling intermittent claudication. This article reviews indications, follow-up protocols, and procedure-related outcomes including perioperative and late mortality, complications, and long-term patency rates, which vary with patient risk factors, vascular disease severity, and hospital volume. Population-based studies have yet to establish whether rates of limb-preserving bypass surgery are related to overall amputation rates, partly because of the continued high rate of primary amputation. The functional benefits of vascular surgery have been traditionally assessed by treadmill protocols and batteries of physical tests. Claudication treatment is increasingly being measured by both generic and disease-specific functional and health-related quality-of-life questionnaires. Patient self-reported measures of physical functioning and walk...