Francis Morey - Academia.edu (original) (raw)

Papers by Francis Morey

Research paper thumbnail of Improving water, sanitation, and hygiene (WASH), with a focus on hand hygiene, globally for community mitigation of COVID-19

PLOS Water

Continuity of key water, sanitation, and hygiene (WASH) infrastructure and WASH practices—for exa... more Continuity of key water, sanitation, and hygiene (WASH) infrastructure and WASH practices—for example, hand hygiene—are among several critical community preventive and mitigation measures to reduce transmission of infectious diseases, including COVID-19 and other respiratory diseases. WASH guidance for COVID-19 prevention may combine existing WASH standards and new COVID-19 guidance. Many existing WASH tools can also be modified for targeted WASH assessments during the COVID-19 pandemic. We partnered with local organizations to develop and deploy tools to assess WASH conditions and practices and subsequently implement, monitor, and evaluate WASH interventions to mitigate COVID-19 in low- and middle-income countries in Latin America and the Caribbean and Africa, focusing on healthcare, community institution, and household settings and hand hygiene specifically. Employing mixed-methods assessments, we observed gaps in access to hand hygiene materials specifically despite most of those...

Research paper thumbnail of Diagnosis of Acute Chagas Disease in a Belizean Child with Evidence of a Multiclonal Trypanosoma cruzi Infection

Diagnosis of Acute Chagas Disease in a Belizean Child with Evidence of a Multiclonal Trypanosoma cruzi Infection

The American Journal of Tropical Medicine and Hygiene

ABSTRACT. In January 2020, we instituted acute febrile illness surveillance in 11 hospitals and c... more ABSTRACT. In January 2020, we instituted acute febrile illness surveillance in 11 hospitals and clinics across Belize. Within 3 months, we diagnosed an acute case of Chagas disease by polymerase chain reaction in a 7-year-old child in the northern part of the country. Phylogenetic analyses of the parasite from the acute blood specimen revealed a multiclonal Trypanosoma cruzi infection, including parasites from the TcII (25.0% of haplotypes), TcIV (2.5% of haplotypes), and TcV (72.5% of haplotypes) discrete typing units. The family reported no history of travel, and three Triatoma species vectors were found within the home. The child’s mother was seronegative for antibodies to T. cruzi, ruling out congenital transmission. Convalescent blood samples documented seroconversion and confirmed acute infection. The child was successfully treated with nifurtimox. This is the first known diagnosed case of acute Chagas infection in Belize, highlighting the need for further investigation and pu...

Research paper thumbnail of Hepatic fascioliasis in Camagüey 1999

Hepatic fascioliasis in Camagüey 1999

Research paper thumbnail of Hipertensión arterial maligna. Su incidencia en un quinquenio

Hipertensión arterial maligna. Su incidencia en un quinquenio

Se realizo un estudio descriptivo para caracterizar la hipertension arterial maligna en el Hospit... more Se realizo un estudio descriptivo para caracterizar la hipertension arterial maligna en el Hospital Manuel Ascunce Domenech de Camaguey, durante un quinquenio. El universo ascendio a 38 enfermos cuyos datos se procesaron en una microcomputadora utilizando el programa Microstad. Los hombres representaron el 65, 7 % del universo, el principal grupo de edad fue de 48 a 67 anos en el que se ubico el 50 %. La hiperuricemia, la diabetes mellitus, la hiperlipoproteinemia y la cardiopatia isquemica fueron los antecedentes personales mas frecuentes. En el 55.3 % predomino la hipertension severa, mediando un periodo de 6 a 10 anos (44, 7 %) para el diagnostico de la hipertension maligna. Las principales lesiones de organos diana fueron la insuficiencia renal, la microproteinuria, el infarto cerebral aterotrombotico, el ataque transitorio de isquemia, la hipertrofia ventricular izquierda y el infarto cardiaco.

Research paper thumbnail of La fasciolasis hepática humana en Camaguey. 1999

La fasciolasis hepática humana en Camaguey. 1999

Se realizo un estudio transversal descriptivo y observacional para caracterizar la infestacion po... more Se realizo un estudio transversal descriptivo y observacional para caracterizar la infestacion por Fasciola hepatica en 25 pacientes ingresados en el Hospital Manuel Ascunce Domenech durante el periodo de enero a mayo de 1999 procedentes del Municipio Esmeralda, Camaguey. Se confecciono un cuestionario cuyos datos se codificaron manualmente y se procesaron en una microcomputadora IBM compatible, utilizando el paquete de programas estadisticos MICROSTAT. Los pacientes mas afectados se ubicaron entre los 51-60 anos de edad (7 para el 28%) Los sintomas mas frecuentes fueron la astenia y el dolor abdominal en hemiabdomen superior con el 84% y 80% respectivamente, mientras que la fiebre fue el principal signo (88%). El 48% de los casos fue ingresado con el diagnostico inicial de Sindrome Febril prolongado de Eosinofilia. La eosinofilia se presento en los 25 pacientes (100%), mientras que el examen parasitologico de las heces, el inmunodiagnostico y la eritrosedimentacion acelerada tuvier...

Research paper thumbnail of Fasciolasis con hematoma hepático. Presentación de tres casos

Fasciolasis con hematoma hepático. Presentación de tres casos

Se realiza la presentacion de tres pacientes con fasciolasis hepatica con hematoma subcapsular de... more Se realiza la presentacion de tres pacientes con fasciolasis hepatica con hematoma subcapsular del higado ingresados en el Hospital Clinico Quirurgico Docente Manuel Ascunce Domenech de Camaguey durante los meses de mayo hasta agosto de 1999 con el objetivo de describir los principales hallazgos del diagnostico. Fue comun en estos enfermos la procedencia del Municipio Esmeralda, habitos alimentarios (ingestion de berro), la perdida de peso, el dolor en hipocondrio derecho, astenia, fiebre y hepatomegalia dolorosa. Los principales resultados de laboratorio fueron: eosinofilia, huevos de Fasciola Hepatica en heces fecales, coproantigeno de Fasciola positivo y eritrosedimentacion acelerada. Se anexan tres figuras con resultado histologico y tomografico de cada paciente. La evolucion en todos los casos fue favorable.

Research paper thumbnail of Ethnic and Gender Disparities in Premature Adult Mortality in Belize 2008-2010

Background Data on disparities in mortality within low and middle income countries are limited, w... more Background Data on disparities in mortality within low and middle income countries are limited, with little published data from the Caribbean or Central America. Our aim was to investigate disparities in overall and cause specific premature adult mortality in the multi-ethnic middle income country of Belize. Methods Mortality data from Belize 2008-2010 classified using the International Classification of Diseases 10 and the 2010 census stratified by age and ethnicity were used to calculate age, sex, and ethnic specific mortality rates for those 15-59 years, and life table analysis was used to estimate the probability of death between the ages of 15 and 59 (45q15). Results The probability of death among those aged 15 to 59 years was 18.1% (women 13.5%, men 22.7%). Creole and Garifuna ethnic groups have three times the 45q15 probability of death compared to Mayan and Mestizo groups (Creole 31.2%, Garifuna 31.1%, Mayan 10.2%, Mestizo 12.0%). This pattern of ethnic disparity existed in both sexes but was greater in men. The probability of death from injuries was 14.8% among Creole men, more than twice the rate of other ethnicities and peaks among young Creole men. These deaths are dominated by homicides and unspecified deaths involving firearms Conclusions Marked disparities in mortality between ethnic groups exist in this Central American/Caribbean country, from rates that are typical of high-income countries to those of low-income countries. The pattern of these extreme differences likely suggests that they reflect underlying social determinants rooted in the country's colonial past.

Research paper thumbnail of Hematoma subcapsular del hígado. Manifestación en tres pacientes con fascioliosis hepática

Hematoma subcapsular del hígado. Manifestación en tres pacientes con fascioliosis hepática

Research paper thumbnail of Improving water, sanitation, and hygiene (WASH), with a focus on hand hygiene, globally for community mitigation of COVID-19

PLOS Water

Continuity of key water, sanitation, and hygiene (WASH) infrastructure and WASH practices—for exa... more Continuity of key water, sanitation, and hygiene (WASH) infrastructure and WASH practices—for example, hand hygiene—are among several critical community preventive and mitigation measures to reduce transmission of infectious diseases, including COVID-19 and other respiratory diseases. WASH guidance for COVID-19 prevention may combine existing WASH standards and new COVID-19 guidance. Many existing WASH tools can also be modified for targeted WASH assessments during the COVID-19 pandemic. We partnered with local organizations to develop and deploy tools to assess WASH conditions and practices and subsequently implement, monitor, and evaluate WASH interventions to mitigate COVID-19 in low- and middle-income countries in Latin America and the Caribbean and Africa, focusing on healthcare, community institution, and household settings and hand hygiene specifically. Employing mixed-methods assessments, we observed gaps in access to hand hygiene materials specifically despite most of those...

Research paper thumbnail of Diagnosis of Acute Chagas Disease in a Belizean Child with Evidence of a Multiclonal Trypanosoma cruzi Infection

Diagnosis of Acute Chagas Disease in a Belizean Child with Evidence of a Multiclonal Trypanosoma cruzi Infection

The American Journal of Tropical Medicine and Hygiene

ABSTRACT. In January 2020, we instituted acute febrile illness surveillance in 11 hospitals and c... more ABSTRACT. In January 2020, we instituted acute febrile illness surveillance in 11 hospitals and clinics across Belize. Within 3 months, we diagnosed an acute case of Chagas disease by polymerase chain reaction in a 7-year-old child in the northern part of the country. Phylogenetic analyses of the parasite from the acute blood specimen revealed a multiclonal Trypanosoma cruzi infection, including parasites from the TcII (25.0% of haplotypes), TcIV (2.5% of haplotypes), and TcV (72.5% of haplotypes) discrete typing units. The family reported no history of travel, and three Triatoma species vectors were found within the home. The child’s mother was seronegative for antibodies to T. cruzi, ruling out congenital transmission. Convalescent blood samples documented seroconversion and confirmed acute infection. The child was successfully treated with nifurtimox. This is the first known diagnosed case of acute Chagas infection in Belize, highlighting the need for further investigation and pu...

Research paper thumbnail of Hepatic fascioliasis in Camagüey 1999

Hepatic fascioliasis in Camagüey 1999

Research paper thumbnail of Hipertensión arterial maligna. Su incidencia en un quinquenio

Hipertensión arterial maligna. Su incidencia en un quinquenio

Se realizo un estudio descriptivo para caracterizar la hipertension arterial maligna en el Hospit... more Se realizo un estudio descriptivo para caracterizar la hipertension arterial maligna en el Hospital Manuel Ascunce Domenech de Camaguey, durante un quinquenio. El universo ascendio a 38 enfermos cuyos datos se procesaron en una microcomputadora utilizando el programa Microstad. Los hombres representaron el 65, 7 % del universo, el principal grupo de edad fue de 48 a 67 anos en el que se ubico el 50 %. La hiperuricemia, la diabetes mellitus, la hiperlipoproteinemia y la cardiopatia isquemica fueron los antecedentes personales mas frecuentes. En el 55.3 % predomino la hipertension severa, mediando un periodo de 6 a 10 anos (44, 7 %) para el diagnostico de la hipertension maligna. Las principales lesiones de organos diana fueron la insuficiencia renal, la microproteinuria, el infarto cerebral aterotrombotico, el ataque transitorio de isquemia, la hipertrofia ventricular izquierda y el infarto cardiaco.

Research paper thumbnail of La fasciolasis hepática humana en Camaguey. 1999

La fasciolasis hepática humana en Camaguey. 1999

Se realizo un estudio transversal descriptivo y observacional para caracterizar la infestacion po... more Se realizo un estudio transversal descriptivo y observacional para caracterizar la infestacion por Fasciola hepatica en 25 pacientes ingresados en el Hospital Manuel Ascunce Domenech durante el periodo de enero a mayo de 1999 procedentes del Municipio Esmeralda, Camaguey. Se confecciono un cuestionario cuyos datos se codificaron manualmente y se procesaron en una microcomputadora IBM compatible, utilizando el paquete de programas estadisticos MICROSTAT. Los pacientes mas afectados se ubicaron entre los 51-60 anos de edad (7 para el 28%) Los sintomas mas frecuentes fueron la astenia y el dolor abdominal en hemiabdomen superior con el 84% y 80% respectivamente, mientras que la fiebre fue el principal signo (88%). El 48% de los casos fue ingresado con el diagnostico inicial de Sindrome Febril prolongado de Eosinofilia. La eosinofilia se presento en los 25 pacientes (100%), mientras que el examen parasitologico de las heces, el inmunodiagnostico y la eritrosedimentacion acelerada tuvier...

Research paper thumbnail of Fasciolasis con hematoma hepático. Presentación de tres casos

Fasciolasis con hematoma hepático. Presentación de tres casos

Se realiza la presentacion de tres pacientes con fasciolasis hepatica con hematoma subcapsular de... more Se realiza la presentacion de tres pacientes con fasciolasis hepatica con hematoma subcapsular del higado ingresados en el Hospital Clinico Quirurgico Docente Manuel Ascunce Domenech de Camaguey durante los meses de mayo hasta agosto de 1999 con el objetivo de describir los principales hallazgos del diagnostico. Fue comun en estos enfermos la procedencia del Municipio Esmeralda, habitos alimentarios (ingestion de berro), la perdida de peso, el dolor en hipocondrio derecho, astenia, fiebre y hepatomegalia dolorosa. Los principales resultados de laboratorio fueron: eosinofilia, huevos de Fasciola Hepatica en heces fecales, coproantigeno de Fasciola positivo y eritrosedimentacion acelerada. Se anexan tres figuras con resultado histologico y tomografico de cada paciente. La evolucion en todos los casos fue favorable.

Research paper thumbnail of Ethnic and Gender Disparities in Premature Adult Mortality in Belize 2008-2010

Background Data on disparities in mortality within low and middle income countries are limited, w... more Background Data on disparities in mortality within low and middle income countries are limited, with little published data from the Caribbean or Central America. Our aim was to investigate disparities in overall and cause specific premature adult mortality in the multi-ethnic middle income country of Belize. Methods Mortality data from Belize 2008-2010 classified using the International Classification of Diseases 10 and the 2010 census stratified by age and ethnicity were used to calculate age, sex, and ethnic specific mortality rates for those 15-59 years, and life table analysis was used to estimate the probability of death between the ages of 15 and 59 (45q15). Results The probability of death among those aged 15 to 59 years was 18.1% (women 13.5%, men 22.7%). Creole and Garifuna ethnic groups have three times the 45q15 probability of death compared to Mayan and Mestizo groups (Creole 31.2%, Garifuna 31.1%, Mayan 10.2%, Mestizo 12.0%). This pattern of ethnic disparity existed in both sexes but was greater in men. The probability of death from injuries was 14.8% among Creole men, more than twice the rate of other ethnicities and peaks among young Creole men. These deaths are dominated by homicides and unspecified deaths involving firearms Conclusions Marked disparities in mortality between ethnic groups exist in this Central American/Caribbean country, from rates that are typical of high-income countries to those of low-income countries. The pattern of these extreme differences likely suggests that they reflect underlying social determinants rooted in the country's colonial past.

Research paper thumbnail of Hematoma subcapsular del hígado. Manifestación en tres pacientes con fascioliosis hepática

Hematoma subcapsular del hígado. Manifestación en tres pacientes con fascioliosis hepática