Mostafa Ali - Academia.edu (original) (raw)

Papers by Mostafa Ali

Research paper thumbnail of Functional Properties of Faba Bean Protein and Effect of Enzymatic Hydrolysis on Its Antioxidant Activity

Zagazig Journal of Agricultural Research, 2019

Protein play an important role in determining structure and texture of various food products. The... more Protein play an important role in determining structure and texture of various food products. Therefore, the goals of this research were to study the functional properties of faba bean protein cultivar, Giza3, compared to ß-Lactoglobulin (ß-Lg) and to hydrolyze this protein using pepsin at different pH values (1.5 and 3) and different incubation periods (0, 5, 10, 60, and 180 min) to characterize the resultant hydrolysates and evaluate their antioxidant activities. The solubility at different pH, emulsifying properties, stability against creaming and oil droplets size, of faba bean protein were tested compared to ß-Lg protein. The findings cleared that the solubility and emulsifying properties of faba protein were very low compared to ß-Lg. Concerning to hydrolysis process, the degree of hydrolysis at pH 1.5 was higher than that at pH 3. The molecular weight distribution bands of faba protein hydrolysates were in the range of 9-98 kDa using SDS-PAGE method while, peptides were in the range of 500-4000 Da using MALDI-TOF MS method. The results of both methods confirmed that the hydrolysis at pH 1.5 was higher than pH 3. Moreover, the enzymatic hydrolysis significantly improved the antioxidant activity of faba bean protein. Hydrolysates produced at pH 3 had a slight high antioxidant activity than at pH 1.5 at all incubation periods. Finally, these results suggest that faba bean hydrolysates could be used in preparing functional foods and as natural antioxidants to prevent oxidation process in food products.

Research paper thumbnail of BIM obstacles in industrial projects : a contractor perspective

Using BIM technology is well established in construction projects, especially in industrial proje... more Using BIM technology is well established in construction projects, especially in industrial projects where a maze of pipes and modules have to be installed in congested work areas under tight time schedule . BIM offers potential benefits (e.g. visualization, collaboration, alignment ...etc.) that can be key for complex project success; however, these benefits have not been fully implemented in industrial projects. The authors worked last two years closely with a construction company -which specialized in oil and gas projectstrying to discover ways to maximize utilization of knowledge embedded in BIM models. Though the partner company has used BIM for long time, we noticed many obstacles that hinder reaping the full benefits of BIM for construction planning and control. These obstacles are related to the ability to extend a model by adding new attributes and to link the model to data from external sources (e.g. cost or schedule control information systems). This paper discusses these...

Research paper thumbnail of HLA listener ? A GUI driven mapping of HLA standard services

High Level Architecture (HLA) is a distributed simulation framework that offers integration, reus... more High Level Architecture (HLA) is a distributed simulation framework that offers integration, reusability, and flexibility. Nonetheless, it has been criticized for its complexity and overwhelming services. Consequently, it has been rarely used on a day-to-day basis in industrial world. A very steep learning curve is one of the main challenge that faces a new user of HLA distributed simulation. The user has to be familiar with different HLA services (e.g. objects and time management) beside a programming language to develop a basic simulation. In order to overcome this challenge, we developed a tool with friendly graphical user interface that encapsulates all HLA services. This tool allows a new user to explore services as described in the standards without the need for programming language. In addition, the interface can be used by an experienced simulator to debug existing federation quickly and efficiently.

Research paper thumbnail of A Framework for Visualizing Heterogeneous Construction Data Using Semantic Web Standards

Advances in Civil Engineering, 2018

3D Visualization provides a mean for communicating different construction activities to diverse a... more 3D Visualization provides a mean for communicating different construction activities to diverse audiences. The scope, level of detail, and time resolution of the 3D visualization process are determined based on the targeted audiences. Developing the 3D visualization requires obtaining and merging heterogeneous data from different sources (such as BIM model and CPM schedule). The data merging process is usually carried out on ad hoc basis for a specific visualization case which limits the reusability of the process. This paper discusses a framework for automatic merging of heterogeneous data to create a visualization. The paper describes developing an ontology which captures concepts related to the visualization process. Then, heterogeneous data sources that are commonly used in construction are fed into the ontology which can be queried to produce different visualization scenarios. The potential of this approach has been demonstrated by providing multiple visualization scenarios tha...

Research paper thumbnail of A method for clustering unlabeled BIM objects using entropy and TF-IDF with RDF encoding

Advanced Engineering Informatics, 2017

Oil and gas projects involve different construction disciplines such as mechanical, structural, a... more Oil and gas projects involve different construction disciplines such as mechanical, structural, and electrical. The current practice in these projects involves creating separate building information models for the different disciplines and compiling them into one model to check for collisions or conflicts. Due to intellectual property, contractual requirements, unfinished design, or technical issues during final model compilation, the final merged model lacks essential data for contractors such as the trade of each object in the model. Nonetheless, the model is issued to contractors who utilize it in different pre-construction planning tasks. However, due to data loss, incompleteness, or inconsistency, the model usability can become limited and the contractor has to review the model manually to extract information from it. This is a lengthy and costly task that becomes more challenging in fast-tracked projects that involve periodically issuing updated Building Information Models. One type of information that contractors need for different planning and estimation purposes is the scope of work for different construction trades in different areas of the project. In many cases, models lack explicit attributes of 3D objects that make it possible to perform an automated query of these objects by trade type. This research suggests a state of the art solution to automate the extraction of this information in such cases. In this paper, we describe a method that utilizes Resource Description Framework (RDF) encoding of BIM data together with Term Frequency-Inverse Document Frequency (TF-IDF) and entropy-based algorithms to automatically group 3D objects based on their trade. The proposed methodology is tested using three actual cases of oil and gas projects with more than four million objects in total. The results show that the proposed method can achieve a 91% purity in the generated groups.

Research paper thumbnail of Constructability : capabilities, implementation, and barriers

Constructability means finding ways to construct effectively. It minimises disputes, cost overrun... more Constructability means finding ways to construct effectively. It minimises disputes, cost overrun, and schedule delays. However, constructability program adoption in construction projects differs from one corporation to another, and the level of implementation (measured in two levels: corporate and project level) extends from highly sophisticated to none at all. Despite its benefits, many construction companies are reluctant to fully implement it due to many barriers (e.g. complacency with status quo and lack of expertise for design firms). In order to improve the effectiveness of constructability programs in construction projects, identification and mitigation of constructability program barriers using gap analysis techniques should be done. This paper illustrates research done with a partner company to measure degree of implementation of constructability in the company. We used CII constructability evaluation matrix to evaluate the degree of implementation of constructability prog...

Research paper thumbnail of Land mine detection with neutron back scattering imaging using a neutron generator

IEEE Transactions on Nuclear Science, 2006

The neutron back scattering technique may be used to search for low-metallic land mines. An advan... more The neutron back scattering technique may be used to search for low-metallic land mines. An advantage of this technique is the speed of detection: the scanning speed may be made comparable to that of a metal detector. The method is sensitive to soil moisture. A limitation of the method is therefore that the soil must be sufficiently dry. The neutrons are produced with a pulsed neutron generator. An image of the back scattered thermal neutron radiation is obtained with a two dimensional position sensitive detector. Getting optimal settings for the detector system is described. The mine detection time as function of the neutron pulse parameters is investigated. Results with various dummy mines are presented.

Research paper thumbnail of Automated Recognition of Unlabeled Items in BIM Models

Construction Research Congress 2016, 2016

Research paper thumbnail of الجودة فى الصناعة

Research paper thumbnail of Studies on Dietary Protein Utilization in Japanese Quail

Research paper thumbnail of Control of emergence hypertension after craniotomy for brain tumor surgery

Neurosciences, Apr 1, 2009

To compare the anti-hypertensive effects of both remifentanil and esmolol infusion. This prospect... more To compare the anti-hypertensive effects of both remifentanil and esmolol infusion. This prospective comparative study was conducted on 20 patients (10 patients in each group), in the Neurosurgical Theater of Kasr Elaini Hospital, Cairo, Egypt from 2006 to 2008. The patients were divided into 2 equal groups. In group one, remifentanil was used as a bolus of one ug/kg intravenous (iv) in 30-60 seconds, followed by infusion at a rate of 0.25-0.5 ug/kg/min until the systolic blood pressure was <140 mm Hg. In group 2, esmolol was given as a 500 ug/kg iv bolus in 30 seconds followed by continued infusion of 100-300 ug/kg/min until systolic blood pressure was <140 mm Hg. Infusion was continued until the patients left the post anesthesia care unit (PACU). The onset time of decreasing blood pressure was shorter in group 2 (40+/-0.01 seconds) than group one (52.5+/-4.47 seconds). The PACU and hospital stay were comparable between both groups. Remifentanil can be used to control blood pressure during emergence of anesthesia after craniotomy for brain tumors. It has higher rapid recovery score than esmolol and other narcotics. In addition, it can be used when esmolol is contraindicated such as in cardiac patients, asthmatics, chronic obstructive pulmonary disease, or during pregnancy. Also, it decreases the need for postoperative analgesia and allows sedation if the infusion is continued as surgical patients are admitted to the ICU.

Research paper thumbnail of Awake craniotomy versus general anesthesia for managing eloquent cortex low-grade gliomas

Neurosciences (Riyadh, Saudi Arabia), 2009

To compare awake craniotomy using conscious sedation technique versus conventional general anesth... more To compare awake craniotomy using conscious sedation technique versus conventional general anesthesia (GA) for excision of low-grade glioma encroaching on eloquent brain. This prospective study included 40 patients ASA classification 1 and 2, aged 23-55 years, harboring low-grade glioma encroaching on eloquent brain. The study was carried out in the Neurosurgical Theatre in Kasr El-Aini Hospital, Cairo, Egypt, from January 2007 to November 2008. Twenty patients (group 1) received GA with endotracheal intubation and controlled ventilation. In group 2, awake craniotomy was carried out using local anesthetic infiltration, and intravenous injection of propofol and fentanyl. Forty patients completed the study. In the awake group, none of the patients received GA, 2 patients developed intraoperative agitation, 5 patients were over-sedated, and none of the awake patients developed intraoperative nausea or vomiting. Four patients in the GA group developed post-operative nausea and vomiting ...

Research paper thumbnail of Living Donor Kidneys: Usefulness of 16-Slice Multi-Detector Row CT for Preoperative Evaluation

The Medical Journal of Cairo University, Dec 1, 2006

To evaluate the efficacy of emergency CT in patients with blunt pancreatic trauma on their admiss... more To evaluate the efficacy of emergency CT in patients with blunt pancreatic trauma on their admission to the hospital and to describe the CT findings of pancreatic parenchymal and main pancreatic duct injuries, we performed a retrospective study. During a 4-year period (2001)(2002)(2003)(2004)(2005), 15 patients (twelve males and three females; age range 4-38 years) were investigated by spiral CT. Ultrasound at admission was obtained in 7 cases and endoscopic retrograde cholangiopancreatography (ERCP) was also obtained in 7 cases. Serum amylase was reviewed at admission in all cases. The imaging findings obtained by the spiral CT were correlated with ultrasound, ERCP and operative findings (when available). At admission, the diagnosis of pancreatic injury was missed by CT in four patients (26.7%). Thus, the sensitivity of CT was 73.3%. ERCP showed rupture of the main pancreatic duct in all cases in which it was performed. One of them was negative on the CT obtained at admission. Serum amylase at admission was elevated in 53.3% of cases. No correlation between the CT features and type of outcome of surgical management could be noted in this study. On retrospective review of the CT examinations obtained at admission, we found that two of the four false negative results could have been avoided. Therefore, proper CT technique and accurate film reading are mandatory for diagnosis of pancreatic injuries. If the CT at admission with proper technique and proper film reading do not reveal evidence of pancreatic injury with the presence of persistent unexplained abdominal pain or elevated serum amylase, we advise to repeat the CT after 24-48 hours.

Research paper thumbnail of Developing a solution for small businesses

Worldwide Hospitality and Tourism Themes, 2015

Research paper thumbnail of Acute low-dose endotoxin treatment results in improved whole-body glucose homeostasis in mice

Metabolism: clinical and experimental, Mar 1, 2017

Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weig... more Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. The goal of this study was to determine the effects of both short-term and long-term increases in endotoxin (lipopolysaccharide, LPS) of a low magnitude on the glucose tolerance and insulin signaling in a human primar...

Research paper thumbnail of Skeletal Muscle-TLR4 Deficient Mice Lack Exercise-induced Cytokine Up-regulation and Mitochondrial Adaptation to Exercise Training: 2675 Board #198 June 3, 9: 30 AM - 11: 00 AM

Medicine and science in sports and exercise, 2016

Research paper thumbnail of Experimental Study for Condensation Heat Transfer Inside Helical Coil

... Mohamed A. Abd Raboh1, Hesham M. Mostafa2, Mostafa AM Ali2 and Amr M. Hassaan3 1Faculty of En... more ... Mohamed A. Abd Raboh1, Hesham M. Mostafa2, Mostafa AM Ali2 and Amr M. Hassaan3 1Faculty of Engineering, Al Azhar University, 2Faculty of Engineering, King Abdulaziz University, 3Higher Technological Institute, Tenth of Ramadan City, 1,3Egypt 2K.SA 1. Introduction ...

Research paper thumbnail of Treatment adherence and beliefs about medicines among Egyptian vitiligo patients

Dermatologic Therapy, 2016

Vitiligo is a chronic disorder of depigmentation that has different treatment modalities, but pat... more Vitiligo is a chronic disorder of depigmentation that has different treatment modalities, but patients' nonadherence is common. This study aimed to assess the influence of patients' medication beliefs on patients' adherence to topical, oral medications, and phototherapy in vitiligo. Between September 2015 and February 2016, 260 patients with vitiligo were asked to fill in the Beliefs about Medicines Questionnaire (BMQ) to assess their beliefs about therapy for vitiligo. Their adherence to the therapy was examined using the 8-item Morisky Medication Adherence Scale (MMAS-8). The MMAS-8 scale and BMQ had good internal consistency (Cronbach's α = 0.78 and 0.66, respectively). Using Morisky's recommended cutoff point, 71% of patients were categorized as low or nonadherent to the scheduled therapy. Patients who perceived specific necessity of dermatological medicines significantly adhered to their therapy (OR 1.23; 95% CI 1.09, 1.38; p = 0.001) whereas patients who had specific concerns about the adverse effects exhibited significant low adherence (OR 0.65; 95% CI 0.56, 0.76; p < 0.001). Positive beliefs about the necessity of medications in vitiligo do not necessarily reflect high adherence. Patients' adherence behavior is a multidimensional and dynamic process. The prolonged course of treatment, its cost, and unsatisfactory outcomes influenced the patients' adherence.

Research paper thumbnail of A randomized, comparative study of dual therapy (doxycycline–rifampin) versus triple therapy (doxycycline–rifampin–levofloxacin) for treating acute/subacute brucellosis

The Brazilian Journal of Infectious Diseases, 2016

The aim of this study was to compare both the efficacy and safety profile of the WHO-recommended,... more The aim of this study was to compare both the efficacy and safety profile of the WHO-recommended, dual therapy (doxycycline-rifampin) to a quinolone-based, triple therapy (doxycycline-rifampin-levofloxacin) for treating acute/subacute brucellosis. We studied 107 consecutive, naïve patients with acute/subacute brucellosis admitted to Assiut University Hospital. Patients were randomly allocated to receive the dual therapy of doxycycline-rifampin (group-A) or to receive the triple therapy of doxycycline-rifampin-levofloxacin (group-B). Acute/subacute brucellosis was diagnosed based on the presence of: (1) contact with animals or fresh animal products, (2) suggestive clinical manifestations of less than one-year duration, and (3) positive antibody titer (1:160) by standard tube agglutination test. There was no significant difference between the two groups regarding their demographic data. Fever was the most frequent manifestation (96.3%). Epigastric pain was the most frequent adverse effect of treatment (12.1%). Group-A patients had a significantly higher relapse rate compared to group-B patients (22.6% versus 9.3%, p-value=0.01). The rate of treatment adverse effects was higher among group-B patients, although not reaching statistical significance (20.4% versus 11.3%, p-value=0.059). Adding levofloxacin to the dual therapy for acute/subacute brucellosis (doxycycline-rifampin) may increase its efficacy in terms of lowering the relapse rate of the disease. Further, larger scale studies are needed before considering modifying the standard, dual therapy for brucellosis.

Research paper thumbnail of Factors affecting organoleptic properties of some snack foods

Research paper thumbnail of Functional Properties of Faba Bean Protein and Effect of Enzymatic Hydrolysis on Its Antioxidant Activity

Zagazig Journal of Agricultural Research, 2019

Protein play an important role in determining structure and texture of various food products. The... more Protein play an important role in determining structure and texture of various food products. Therefore, the goals of this research were to study the functional properties of faba bean protein cultivar, Giza3, compared to ß-Lactoglobulin (ß-Lg) and to hydrolyze this protein using pepsin at different pH values (1.5 and 3) and different incubation periods (0, 5, 10, 60, and 180 min) to characterize the resultant hydrolysates and evaluate their antioxidant activities. The solubility at different pH, emulsifying properties, stability against creaming and oil droplets size, of faba bean protein were tested compared to ß-Lg protein. The findings cleared that the solubility and emulsifying properties of faba protein were very low compared to ß-Lg. Concerning to hydrolysis process, the degree of hydrolysis at pH 1.5 was higher than that at pH 3. The molecular weight distribution bands of faba protein hydrolysates were in the range of 9-98 kDa using SDS-PAGE method while, peptides were in the range of 500-4000 Da using MALDI-TOF MS method. The results of both methods confirmed that the hydrolysis at pH 1.5 was higher than pH 3. Moreover, the enzymatic hydrolysis significantly improved the antioxidant activity of faba bean protein. Hydrolysates produced at pH 3 had a slight high antioxidant activity than at pH 1.5 at all incubation periods. Finally, these results suggest that faba bean hydrolysates could be used in preparing functional foods and as natural antioxidants to prevent oxidation process in food products.

Research paper thumbnail of BIM obstacles in industrial projects : a contractor perspective

Using BIM technology is well established in construction projects, especially in industrial proje... more Using BIM technology is well established in construction projects, especially in industrial projects where a maze of pipes and modules have to be installed in congested work areas under tight time schedule . BIM offers potential benefits (e.g. visualization, collaboration, alignment ...etc.) that can be key for complex project success; however, these benefits have not been fully implemented in industrial projects. The authors worked last two years closely with a construction company -which specialized in oil and gas projectstrying to discover ways to maximize utilization of knowledge embedded in BIM models. Though the partner company has used BIM for long time, we noticed many obstacles that hinder reaping the full benefits of BIM for construction planning and control. These obstacles are related to the ability to extend a model by adding new attributes and to link the model to data from external sources (e.g. cost or schedule control information systems). This paper discusses these...

Research paper thumbnail of HLA listener ? A GUI driven mapping of HLA standard services

High Level Architecture (HLA) is a distributed simulation framework that offers integration, reus... more High Level Architecture (HLA) is a distributed simulation framework that offers integration, reusability, and flexibility. Nonetheless, it has been criticized for its complexity and overwhelming services. Consequently, it has been rarely used on a day-to-day basis in industrial world. A very steep learning curve is one of the main challenge that faces a new user of HLA distributed simulation. The user has to be familiar with different HLA services (e.g. objects and time management) beside a programming language to develop a basic simulation. In order to overcome this challenge, we developed a tool with friendly graphical user interface that encapsulates all HLA services. This tool allows a new user to explore services as described in the standards without the need for programming language. In addition, the interface can be used by an experienced simulator to debug existing federation quickly and efficiently.

Research paper thumbnail of A Framework for Visualizing Heterogeneous Construction Data Using Semantic Web Standards

Advances in Civil Engineering, 2018

3D Visualization provides a mean for communicating different construction activities to diverse a... more 3D Visualization provides a mean for communicating different construction activities to diverse audiences. The scope, level of detail, and time resolution of the 3D visualization process are determined based on the targeted audiences. Developing the 3D visualization requires obtaining and merging heterogeneous data from different sources (such as BIM model and CPM schedule). The data merging process is usually carried out on ad hoc basis for a specific visualization case which limits the reusability of the process. This paper discusses a framework for automatic merging of heterogeneous data to create a visualization. The paper describes developing an ontology which captures concepts related to the visualization process. Then, heterogeneous data sources that are commonly used in construction are fed into the ontology which can be queried to produce different visualization scenarios. The potential of this approach has been demonstrated by providing multiple visualization scenarios tha...

Research paper thumbnail of A method for clustering unlabeled BIM objects using entropy and TF-IDF with RDF encoding

Advanced Engineering Informatics, 2017

Oil and gas projects involve different construction disciplines such as mechanical, structural, a... more Oil and gas projects involve different construction disciplines such as mechanical, structural, and electrical. The current practice in these projects involves creating separate building information models for the different disciplines and compiling them into one model to check for collisions or conflicts. Due to intellectual property, contractual requirements, unfinished design, or technical issues during final model compilation, the final merged model lacks essential data for contractors such as the trade of each object in the model. Nonetheless, the model is issued to contractors who utilize it in different pre-construction planning tasks. However, due to data loss, incompleteness, or inconsistency, the model usability can become limited and the contractor has to review the model manually to extract information from it. This is a lengthy and costly task that becomes more challenging in fast-tracked projects that involve periodically issuing updated Building Information Models. One type of information that contractors need for different planning and estimation purposes is the scope of work for different construction trades in different areas of the project. In many cases, models lack explicit attributes of 3D objects that make it possible to perform an automated query of these objects by trade type. This research suggests a state of the art solution to automate the extraction of this information in such cases. In this paper, we describe a method that utilizes Resource Description Framework (RDF) encoding of BIM data together with Term Frequency-Inverse Document Frequency (TF-IDF) and entropy-based algorithms to automatically group 3D objects based on their trade. The proposed methodology is tested using three actual cases of oil and gas projects with more than four million objects in total. The results show that the proposed method can achieve a 91% purity in the generated groups.

Research paper thumbnail of Constructability : capabilities, implementation, and barriers

Constructability means finding ways to construct effectively. It minimises disputes, cost overrun... more Constructability means finding ways to construct effectively. It minimises disputes, cost overrun, and schedule delays. However, constructability program adoption in construction projects differs from one corporation to another, and the level of implementation (measured in two levels: corporate and project level) extends from highly sophisticated to none at all. Despite its benefits, many construction companies are reluctant to fully implement it due to many barriers (e.g. complacency with status quo and lack of expertise for design firms). In order to improve the effectiveness of constructability programs in construction projects, identification and mitigation of constructability program barriers using gap analysis techniques should be done. This paper illustrates research done with a partner company to measure degree of implementation of constructability in the company. We used CII constructability evaluation matrix to evaluate the degree of implementation of constructability prog...

Research paper thumbnail of Land mine detection with neutron back scattering imaging using a neutron generator

IEEE Transactions on Nuclear Science, 2006

The neutron back scattering technique may be used to search for low-metallic land mines. An advan... more The neutron back scattering technique may be used to search for low-metallic land mines. An advantage of this technique is the speed of detection: the scanning speed may be made comparable to that of a metal detector. The method is sensitive to soil moisture. A limitation of the method is therefore that the soil must be sufficiently dry. The neutrons are produced with a pulsed neutron generator. An image of the back scattered thermal neutron radiation is obtained with a two dimensional position sensitive detector. Getting optimal settings for the detector system is described. The mine detection time as function of the neutron pulse parameters is investigated. Results with various dummy mines are presented.

Research paper thumbnail of Automated Recognition of Unlabeled Items in BIM Models

Construction Research Congress 2016, 2016

Research paper thumbnail of الجودة فى الصناعة

Research paper thumbnail of Studies on Dietary Protein Utilization in Japanese Quail

Research paper thumbnail of Control of emergence hypertension after craniotomy for brain tumor surgery

Neurosciences, Apr 1, 2009

To compare the anti-hypertensive effects of both remifentanil and esmolol infusion. This prospect... more To compare the anti-hypertensive effects of both remifentanil and esmolol infusion. This prospective comparative study was conducted on 20 patients (10 patients in each group), in the Neurosurgical Theater of Kasr Elaini Hospital, Cairo, Egypt from 2006 to 2008. The patients were divided into 2 equal groups. In group one, remifentanil was used as a bolus of one ug/kg intravenous (iv) in 30-60 seconds, followed by infusion at a rate of 0.25-0.5 ug/kg/min until the systolic blood pressure was <140 mm Hg. In group 2, esmolol was given as a 500 ug/kg iv bolus in 30 seconds followed by continued infusion of 100-300 ug/kg/min until systolic blood pressure was <140 mm Hg. Infusion was continued until the patients left the post anesthesia care unit (PACU). The onset time of decreasing blood pressure was shorter in group 2 (40+/-0.01 seconds) than group one (52.5+/-4.47 seconds). The PACU and hospital stay were comparable between both groups. Remifentanil can be used to control blood pressure during emergence of anesthesia after craniotomy for brain tumors. It has higher rapid recovery score than esmolol and other narcotics. In addition, it can be used when esmolol is contraindicated such as in cardiac patients, asthmatics, chronic obstructive pulmonary disease, or during pregnancy. Also, it decreases the need for postoperative analgesia and allows sedation if the infusion is continued as surgical patients are admitted to the ICU.

Research paper thumbnail of Awake craniotomy versus general anesthesia for managing eloquent cortex low-grade gliomas

Neurosciences (Riyadh, Saudi Arabia), 2009

To compare awake craniotomy using conscious sedation technique versus conventional general anesth... more To compare awake craniotomy using conscious sedation technique versus conventional general anesthesia (GA) for excision of low-grade glioma encroaching on eloquent brain. This prospective study included 40 patients ASA classification 1 and 2, aged 23-55 years, harboring low-grade glioma encroaching on eloquent brain. The study was carried out in the Neurosurgical Theatre in Kasr El-Aini Hospital, Cairo, Egypt, from January 2007 to November 2008. Twenty patients (group 1) received GA with endotracheal intubation and controlled ventilation. In group 2, awake craniotomy was carried out using local anesthetic infiltration, and intravenous injection of propofol and fentanyl. Forty patients completed the study. In the awake group, none of the patients received GA, 2 patients developed intraoperative agitation, 5 patients were over-sedated, and none of the awake patients developed intraoperative nausea or vomiting. Four patients in the GA group developed post-operative nausea and vomiting ...

Research paper thumbnail of Living Donor Kidneys: Usefulness of 16-Slice Multi-Detector Row CT for Preoperative Evaluation

The Medical Journal of Cairo University, Dec 1, 2006

To evaluate the efficacy of emergency CT in patients with blunt pancreatic trauma on their admiss... more To evaluate the efficacy of emergency CT in patients with blunt pancreatic trauma on their admission to the hospital and to describe the CT findings of pancreatic parenchymal and main pancreatic duct injuries, we performed a retrospective study. During a 4-year period (2001)(2002)(2003)(2004)(2005), 15 patients (twelve males and three females; age range 4-38 years) were investigated by spiral CT. Ultrasound at admission was obtained in 7 cases and endoscopic retrograde cholangiopancreatography (ERCP) was also obtained in 7 cases. Serum amylase was reviewed at admission in all cases. The imaging findings obtained by the spiral CT were correlated with ultrasound, ERCP and operative findings (when available). At admission, the diagnosis of pancreatic injury was missed by CT in four patients (26.7%). Thus, the sensitivity of CT was 73.3%. ERCP showed rupture of the main pancreatic duct in all cases in which it was performed. One of them was negative on the CT obtained at admission. Serum amylase at admission was elevated in 53.3% of cases. No correlation between the CT features and type of outcome of surgical management could be noted in this study. On retrospective review of the CT examinations obtained at admission, we found that two of the four false negative results could have been avoided. Therefore, proper CT technique and accurate film reading are mandatory for diagnosis of pancreatic injuries. If the CT at admission with proper technique and proper film reading do not reveal evidence of pancreatic injury with the presence of persistent unexplained abdominal pain or elevated serum amylase, we advise to repeat the CT after 24-48 hours.

Research paper thumbnail of Developing a solution for small businesses

Worldwide Hospitality and Tourism Themes, 2015

Research paper thumbnail of Acute low-dose endotoxin treatment results in improved whole-body glucose homeostasis in mice

Metabolism: clinical and experimental, Mar 1, 2017

Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weig... more Obese individuals present with an increased inflammatory tone as compared to healthy, normal-weight individuals, which is associated with insulin resistance. One factor hypothesized to contribute to increased inflammation in obese and diabetic states is elevated blood endotoxin levels, a condition known as metabolic endotoxemia. In non-obese and insulin sensitive individuals, circulating endotoxin concentrations fluctuate over the course of the day with elevations in the post-prandial state that return to baseline levels in the post-absorptive state. Evidence suggests that high-fat feeding alters these fluctuations causing endotoxin levels to remain high throughout the day. The effects of alterations in endotoxin levels on glucose metabolism are not clearly understood. The goal of this study was to determine the effects of both short-term and long-term increases in endotoxin (lipopolysaccharide, LPS) of a low magnitude on the glucose tolerance and insulin signaling in a human primar...

Research paper thumbnail of Skeletal Muscle-TLR4 Deficient Mice Lack Exercise-induced Cytokine Up-regulation and Mitochondrial Adaptation to Exercise Training: 2675 Board #198 June 3, 9: 30 AM - 11: 00 AM

Medicine and science in sports and exercise, 2016

Research paper thumbnail of Experimental Study for Condensation Heat Transfer Inside Helical Coil

... Mohamed A. Abd Raboh1, Hesham M. Mostafa2, Mostafa AM Ali2 and Amr M. Hassaan3 1Faculty of En... more ... Mohamed A. Abd Raboh1, Hesham M. Mostafa2, Mostafa AM Ali2 and Amr M. Hassaan3 1Faculty of Engineering, Al Azhar University, 2Faculty of Engineering, King Abdulaziz University, 3Higher Technological Institute, Tenth of Ramadan City, 1,3Egypt 2K.SA 1. Introduction ...

Research paper thumbnail of Treatment adherence and beliefs about medicines among Egyptian vitiligo patients

Dermatologic Therapy, 2016

Vitiligo is a chronic disorder of depigmentation that has different treatment modalities, but pat... more Vitiligo is a chronic disorder of depigmentation that has different treatment modalities, but patients' nonadherence is common. This study aimed to assess the influence of patients' medication beliefs on patients' adherence to topical, oral medications, and phototherapy in vitiligo. Between September 2015 and February 2016, 260 patients with vitiligo were asked to fill in the Beliefs about Medicines Questionnaire (BMQ) to assess their beliefs about therapy for vitiligo. Their adherence to the therapy was examined using the 8-item Morisky Medication Adherence Scale (MMAS-8). The MMAS-8 scale and BMQ had good internal consistency (Cronbach's α = 0.78 and 0.66, respectively). Using Morisky's recommended cutoff point, 71% of patients were categorized as low or nonadherent to the scheduled therapy. Patients who perceived specific necessity of dermatological medicines significantly adhered to their therapy (OR 1.23; 95% CI 1.09, 1.38; p = 0.001) whereas patients who had specific concerns about the adverse effects exhibited significant low adherence (OR 0.65; 95% CI 0.56, 0.76; p < 0.001). Positive beliefs about the necessity of medications in vitiligo do not necessarily reflect high adherence. Patients' adherence behavior is a multidimensional and dynamic process. The prolonged course of treatment, its cost, and unsatisfactory outcomes influenced the patients' adherence.

Research paper thumbnail of A randomized, comparative study of dual therapy (doxycycline–rifampin) versus triple therapy (doxycycline–rifampin–levofloxacin) for treating acute/subacute brucellosis

The Brazilian Journal of Infectious Diseases, 2016

The aim of this study was to compare both the efficacy and safety profile of the WHO-recommended,... more The aim of this study was to compare both the efficacy and safety profile of the WHO-recommended, dual therapy (doxycycline-rifampin) to a quinolone-based, triple therapy (doxycycline-rifampin-levofloxacin) for treating acute/subacute brucellosis. We studied 107 consecutive, naïve patients with acute/subacute brucellosis admitted to Assiut University Hospital. Patients were randomly allocated to receive the dual therapy of doxycycline-rifampin (group-A) or to receive the triple therapy of doxycycline-rifampin-levofloxacin (group-B). Acute/subacute brucellosis was diagnosed based on the presence of: (1) contact with animals or fresh animal products, (2) suggestive clinical manifestations of less than one-year duration, and (3) positive antibody titer (1:160) by standard tube agglutination test. There was no significant difference between the two groups regarding their demographic data. Fever was the most frequent manifestation (96.3%). Epigastric pain was the most frequent adverse effect of treatment (12.1%). Group-A patients had a significantly higher relapse rate compared to group-B patients (22.6% versus 9.3%, p-value=0.01). The rate of treatment adverse effects was higher among group-B patients, although not reaching statistical significance (20.4% versus 11.3%, p-value=0.059). Adding levofloxacin to the dual therapy for acute/subacute brucellosis (doxycycline-rifampin) may increase its efficacy in terms of lowering the relapse rate of the disease. Further, larger scale studies are needed before considering modifying the standard, dual therapy for brucellosis.

Research paper thumbnail of Factors affecting organoleptic properties of some snack foods