Nasir Muda - Academia.edu (original) (raw)

Papers by Nasir Muda

Research paper thumbnail of Percutaneous mitral valve repair with the MitraClip system in a patient with subacute severe mitral regurgitation caused by papillary muscle rupture

Anadolu Kardiyoloji Dergisi/The Anatolian Journal of Cardiology, 2014

Research paper thumbnail of Routine Transradial Coronary Angiography in the Malaysian Population

Asian …, 2001

... Devan Pillay, MRCP , Lam Kai Huat, MRCP , Sanjiv Joshi, MRCP , Mohd Nasir Muda, MRCP ,Zainal ... more ... Devan Pillay, MRCP , Lam Kai Huat, MRCP , Sanjiv Joshi, MRCP , Mohd Nasir Muda, MRCP ,Zainal Abidin Abdul Hamid, MRCP ... The authors would like to thank Encik Faizal Ramli for the statistical analysis of the data and Puan Azliza Abdullah for typing the manuscript. ...

Research paper thumbnail of The MitraClip Asia-Pacific registry: Differences in outcomes between functional and degenerative mitral regurgitation

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, Jan 28, 2015

The objective of this study is to describe and compare the use of the MitraClip therapy in mitral... more The objective of this study is to describe and compare the use of the MitraClip therapy in mitral regurgitation (MR) patients with degenerative MR (DMR) and functional MR (FMR). Percutaneous edge-to-edge repair of severe MR using the MitraClip device is approved for use in the USA for high risk DMR while European guidelines include its use in FMR patients as well. The MitraClip in the Asia-Pacific Registry (MARS) is a multicenter retrospective registry, involving eight sites in five Asia-Pacific countries. Clinical and echocardiographic characteristics, procedural outcomes and 1-month outcomes [death and major adverse events (MAE)] were compared between FMR and DMR patients treated with the MitraClip. A total of 163 patients were included from 2011 to 2014. The acute procedural success rates for FMR (95.5%, n = 84) and DMR (92%, n = 69) were similar (P = 0.515). 45% of FMR had ≥2 clips inserted compared to 60% of those with DMR (P = 0.064).The 30-day mortality rate for FMR and DMR w...

Research paper thumbnail of The MitraClip Asia-Pacific registry: Differences in outcomes between functional and degenerative mitral regurgitation

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, Jan 28, 2015

The objective of this study is to describe and compare the use of the MitraClip therapy in mitral... more The objective of this study is to describe and compare the use of the MitraClip therapy in mitral regurgitation (MR) patients with degenerative MR (DMR) and functional MR (FMR). Percutaneous edge-to-edge repair of severe MR using the MitraClip device is approved for use in the USA for high risk DMR while European guidelines include its use in FMR patients as well. The MitraClip in the Asia-Pacific Registry (MARS) is a multicenter retrospective registry, involving eight sites in five Asia-Pacific countries. Clinical and echocardiographic characteristics, procedural outcomes and 1-month outcomes [death and major adverse events (MAE)] were compared between FMR and DMR patients treated with the MitraClip. A total of 163 patients were included from 2011 to 2014. The acute procedural success rates for FMR (95.5%, n = 84) and DMR (92%, n = 69) were similar (P = 0.515). 45% of FMR had ≥2 clips inserted compared to 60% of those with DMR (P = 0.064).The 30-day mortality rate for FMR and DMR w...

Research paper thumbnail of TCT-697 Outcomes from MitraClip Therapy in Functional Compared to Degenerative Mitral Regurgitation: Multi-centre Experience from the MitraClip Asia-Pacific Registry (MARS)

Journal of the American College of Cardiology, 2013

Research paper thumbnail of P2-58 Tissue Doppler Isovolemic Myocardial Acceleration – a Novel and Useful Index in the Assessment of Right Ventricular Systolic Function

International Journal of Cardiology, 2007

(≤45), or prosthetic valves. The intensity of the first heart sound S1, defined as the largest pe... more (≤45), or prosthetic valves. The intensity of the first heart sound S1, defined as the largest peak to peak amplitude, was compared to the intensity of the second heart sound, S2 and expressed as the (S1/S2) ratio. Results: We studied 61 patients, 18 to 94 years of age, ejection fraction 12% to 74%. S1/S2 ratios ranged from 0.30 to 5.16 at the apical area, 0.25 to 5.34 at the aortic area and 0.32 to 3.94 at the pulmonic area. S1/S2 ratios recorded at the three areas were each compared between the groups with normal versus low EF (<50%). The median S1/S2 ratios at the pulmonic and aortic areas were significantly lower in the group with decreased vs normal EF (0.61 vs 1.18, p=0.001 for pulmonic S1/S2; 0.97 vs 1.34, p=0.04 for aortic S1/S2). However, there was no significant difference in the median S1/S2 ratios recorded at the apex between the two groups of EF (1.70 vs 1.94, p=0.28). PR intervals were not significantly different between the groups. Conclusions: Patients with decreased left ventricular EF were found to have reduced S1/S2 ratios recorded at the aortic and pulmonic areas. Decreased dp/dt associated with low EF may contribute to diminished S1. This preliminary study introduces a promising bedside method using a digital hand-held phonocardiographic device to screen for left ventricular failure based on reduced S1/S2 ratios.

Research paper thumbnail of Percutaneous mitral valve repair with the MitraClip system: acute results from a real world setting

European Heart Journal, 2010

This study sought to evaluate the feasibility and early outcomes of a percutaneous edge-to-edge r... more This study sought to evaluate the feasibility and early outcomes of a percutaneous edge-to-edge repair approach for mitral valve regurgitation with the MitraClip w system (Evalve, Inc., Menlo Park, CA, USA).

Research paper thumbnail of Percutaneous mitral valve repair with the MitraClip system in a patient with subacute severe mitral regurgitation caused by papillary muscle rupture

Anadolu Kardiyoloji Dergisi/The Anatolian Journal of Cardiology, 2014

Research paper thumbnail of Routine Transradial Coronary Angiography in the Malaysian Population

Asian …, 2001

... Devan Pillay, MRCP , Lam Kai Huat, MRCP , Sanjiv Joshi, MRCP , Mohd Nasir Muda, MRCP ,Zainal ... more ... Devan Pillay, MRCP , Lam Kai Huat, MRCP , Sanjiv Joshi, MRCP , Mohd Nasir Muda, MRCP ,Zainal Abidin Abdul Hamid, MRCP ... The authors would like to thank Encik Faizal Ramli for the statistical analysis of the data and Puan Azliza Abdullah for typing the manuscript. ...

Research paper thumbnail of The MitraClip Asia-Pacific registry: Differences in outcomes between functional and degenerative mitral regurgitation

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, Jan 28, 2015

The objective of this study is to describe and compare the use of the MitraClip therapy in mitral... more The objective of this study is to describe and compare the use of the MitraClip therapy in mitral regurgitation (MR) patients with degenerative MR (DMR) and functional MR (FMR). Percutaneous edge-to-edge repair of severe MR using the MitraClip device is approved for use in the USA for high risk DMR while European guidelines include its use in FMR patients as well. The MitraClip in the Asia-Pacific Registry (MARS) is a multicenter retrospective registry, involving eight sites in five Asia-Pacific countries. Clinical and echocardiographic characteristics, procedural outcomes and 1-month outcomes [death and major adverse events (MAE)] were compared between FMR and DMR patients treated with the MitraClip. A total of 163 patients were included from 2011 to 2014. The acute procedural success rates for FMR (95.5%, n = 84) and DMR (92%, n = 69) were similar (P = 0.515). 45% of FMR had ≥2 clips inserted compared to 60% of those with DMR (P = 0.064).The 30-day mortality rate for FMR and DMR w...

Research paper thumbnail of The MitraClip Asia-Pacific registry: Differences in outcomes between functional and degenerative mitral regurgitation

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, Jan 28, 2015

The objective of this study is to describe and compare the use of the MitraClip therapy in mitral... more The objective of this study is to describe and compare the use of the MitraClip therapy in mitral regurgitation (MR) patients with degenerative MR (DMR) and functional MR (FMR). Percutaneous edge-to-edge repair of severe MR using the MitraClip device is approved for use in the USA for high risk DMR while European guidelines include its use in FMR patients as well. The MitraClip in the Asia-Pacific Registry (MARS) is a multicenter retrospective registry, involving eight sites in five Asia-Pacific countries. Clinical and echocardiographic characteristics, procedural outcomes and 1-month outcomes [death and major adverse events (MAE)] were compared between FMR and DMR patients treated with the MitraClip. A total of 163 patients were included from 2011 to 2014. The acute procedural success rates for FMR (95.5%, n = 84) and DMR (92%, n = 69) were similar (P = 0.515). 45% of FMR had ≥2 clips inserted compared to 60% of those with DMR (P = 0.064).The 30-day mortality rate for FMR and DMR w...

Research paper thumbnail of TCT-697 Outcomes from MitraClip Therapy in Functional Compared to Degenerative Mitral Regurgitation: Multi-centre Experience from the MitraClip Asia-Pacific Registry (MARS)

Journal of the American College of Cardiology, 2013

Research paper thumbnail of P2-58 Tissue Doppler Isovolemic Myocardial Acceleration – a Novel and Useful Index in the Assessment of Right Ventricular Systolic Function

International Journal of Cardiology, 2007

(≤45), or prosthetic valves. The intensity of the first heart sound S1, defined as the largest pe... more (≤45), or prosthetic valves. The intensity of the first heart sound S1, defined as the largest peak to peak amplitude, was compared to the intensity of the second heart sound, S2 and expressed as the (S1/S2) ratio. Results: We studied 61 patients, 18 to 94 years of age, ejection fraction 12% to 74%. S1/S2 ratios ranged from 0.30 to 5.16 at the apical area, 0.25 to 5.34 at the aortic area and 0.32 to 3.94 at the pulmonic area. S1/S2 ratios recorded at the three areas were each compared between the groups with normal versus low EF (<50%). The median S1/S2 ratios at the pulmonic and aortic areas were significantly lower in the group with decreased vs normal EF (0.61 vs 1.18, p=0.001 for pulmonic S1/S2; 0.97 vs 1.34, p=0.04 for aortic S1/S2). However, there was no significant difference in the median S1/S2 ratios recorded at the apex between the two groups of EF (1.70 vs 1.94, p=0.28). PR intervals were not significantly different between the groups. Conclusions: Patients with decreased left ventricular EF were found to have reduced S1/S2 ratios recorded at the aortic and pulmonic areas. Decreased dp/dt associated with low EF may contribute to diminished S1. This preliminary study introduces a promising bedside method using a digital hand-held phonocardiographic device to screen for left ventricular failure based on reduced S1/S2 ratios.

Research paper thumbnail of Percutaneous mitral valve repair with the MitraClip system: acute results from a real world setting

European Heart Journal, 2010

This study sought to evaluate the feasibility and early outcomes of a percutaneous edge-to-edge r... more This study sought to evaluate the feasibility and early outcomes of a percutaneous edge-to-edge repair approach for mitral valve regurgitation with the MitraClip w system (Evalve, Inc., Menlo Park, CA, USA).