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Papers by Muhammad Hassan Raza

Research paper thumbnail of The Surgical Results in Pure Endoscopic Endonasal Trans-sphenoidal Surgeries in 403 Pituitary Adenomas: An 8-Years of Experience from a Single Neurosurgical Unit

Pakistan Journal Of Neurological Surgery, 2021

Objective: To review and report the results in pure endoscopic endonasal trans-sphenoidal surger... more Objective: To review and report the results in pure endoscopic endonasal trans-sphenoidal surgery done at our unit for pituitary adenomas (PAs) in last 8 years. Material and Methods: We reviewed 403 consecutive patients who underwent pure endoscopic endonasal trans-sphenoidal surgery for newly diagnosed pituitary adenomas between August 2012 and July 2020 at our neurosurgical unit. Endocrinological, demographic features and outcomes, their complications, and duration of stay in hospital were assessed in these patients who were operated in our neurosurgical Unit. The Mean Follow-up on average was 3.5 months. Results: 403 consecutive cases were reviewed. Majority of cases were in the 4th decade of life at presentation. 227 (56%) were non-functioning pituitary tumors and 176 (44%) were hormone secreting pituitary adenomas. Thirty-one (7.7%) complications were observed in 28 post-operative patients. The most frequently observed complication was diabetes insipidus (temporary in 19 (5%...

Research paper thumbnail of Anterior Cervical Discectomy and Fusion: Operative Technique and Post-Operative Complications – An Experience in a Tertiary Care Hospital

Pakistan Journal Of Neurological Surgery, 2020

Background and Objective: The most common spinal procedure in our set up to address various disor... more Background and Objective: The most common spinal procedure in our set up to address various disorders of the cervical spine like prolapsed intervertebral disc, trauma, and degenerative disc disease is an anterior cervical discectomy and fusion (ACDF). As there is no technique without complication, this procedure is also related with certain important complications. We evaluated post-operative complications of ACDF in our institution.Material and Methods: The preoperative data of 148 patients who were operated in last 3 years for ACDF isincluded in the study. Patients with previous neck surgery are excluded.Results: The most commonly performed surgical interventions is single level ACDF (65%). Dysphagia is mostsignificant (16%) complication. After which neurological deterioration (9%) with equal incidence of RecurrentLaryngeal Nerve Palsy and wound infection that is 8% each.Conclusion: The most common post-operative complications are dysphagia and worsening of preexistingneurology an...

Research paper thumbnail of Clinical Outcome of Percutaneous Radiofrequency Rhizotomy for Trigeminal Neuralgia at a Tertiary Care Hospital

Pakistan Journal Of Neurological Surgery, 2019

Background: - Trigeminal neuralgia is a disease typically characterized by involuntary attacks of... more Background: - Trigeminal neuralgia is a disease typically characterized by involuntary attacks of lancinating pain in the distribution of the trigeminal nerve that are activated by non-noxious stimuli. Numerous anticonvulsants, either alone or in combination, remain the first choice in the medical treatment of trigeminal neuralgia.3If the disease becomes non responsive, there are numerous surgical options like micro vascular decompression or minimally invasive percutaneous lesioning of the trigeminal nerve, such as glycerol rhizolysis, Radiofrequency Rhizotomy, and balloon compression. Objective: - To determine efficacy of percutaneous Radiofrequency Rhizotomy for trigeminal neuralgia in terms of early pain relief in a tertiary care hospital. Methods: - 62 patients with refractory trigeminal neuralgia or lancinating, recurrent episodes of pain in the distribution of Ophthalmic (V1) and Mandibular (V3) branches of trigeminal nerve, not responsive to 6 months of conservative treatmen...

Research paper thumbnail of Outcome of Anterior Fusion Technique for Multilevel Cervical Spondylotic Myelopathy

Pakistan Journal Of Neurological Surgery, 2019

Objective: To asses’ surgical parameters, complications, clinical and radiological outcomes in ... more Objective: To asses’ surgical parameters, complications, clinical and radiological outcomes in the treatment of 2-, 3- and 4-levels Cervical Spondylotic Myelopathy . Methods: A total of 90 patients with 2-, 3- or 4-level CSM who underwent anterior decompression and fusion procedures between January 2017 and October 2018 were divided into three different groups, the 2-level group (65 patients), the 3-level group (20 patients) and the 4-level group (5 patients). The clinical and Radiographic outcomes like Neck Disability Index (NDI) score, hospital stay, blood loss, operation time, fusion rate, cervical lordosis, cervical range of motion (ROM), and complications were compared between different procedures. Results: At a minimum of 1-year follow-up, no statistical differences in NDI score, hospital stay, fusion rate and cervical lordosis were found among the 3 groups. However, the mean postoperative NDI score of the 4-level group was significantly higher than that in the other two gro...

Research paper thumbnail of Carbon monoxide poisoning with an atypical presentation on MRI: Case report and literature review

Annals of Medicine and Surgery

Research paper thumbnail of The Surgical Results in Pure Endoscopic Endonasal Trans-sphenoidal Surgeries in 403 Pituitary Adenomas: An 8-Years of Experience from a Single Neurosurgical Unit

Pakistan Journal Of Neurological Surgery, 2021

Objective: To review and report the results in pure endoscopic endonasal trans-sphenoidal surger... more Objective: To review and report the results in pure endoscopic endonasal trans-sphenoidal surgery done at our unit for pituitary adenomas (PAs) in last 8 years. Material and Methods: We reviewed 403 consecutive patients who underwent pure endoscopic endonasal trans-sphenoidal surgery for newly diagnosed pituitary adenomas between August 2012 and July 2020 at our neurosurgical unit. Endocrinological, demographic features and outcomes, their complications, and duration of stay in hospital were assessed in these patients who were operated in our neurosurgical Unit. The Mean Follow-up on average was 3.5 months. Results: 403 consecutive cases were reviewed. Majority of cases were in the 4th decade of life at presentation. 227 (56%) were non-functioning pituitary tumors and 176 (44%) were hormone secreting pituitary adenomas. Thirty-one (7.7%) complications were observed in 28 post-operative patients. The most frequently observed complication was diabetes insipidus (temporary in 19 (5%...

Research paper thumbnail of Anterior Cervical Discectomy and Fusion: Operative Technique and Post-Operative Complications – An Experience in a Tertiary Care Hospital

Pakistan Journal Of Neurological Surgery, 2020

Background and Objective: The most common spinal procedure in our set up to address various disor... more Background and Objective: The most common spinal procedure in our set up to address various disorders of the cervical spine like prolapsed intervertebral disc, trauma, and degenerative disc disease is an anterior cervical discectomy and fusion (ACDF). As there is no technique without complication, this procedure is also related with certain important complications. We evaluated post-operative complications of ACDF in our institution.Material and Methods: The preoperative data of 148 patients who were operated in last 3 years for ACDF isincluded in the study. Patients with previous neck surgery are excluded.Results: The most commonly performed surgical interventions is single level ACDF (65%). Dysphagia is mostsignificant (16%) complication. After which neurological deterioration (9%) with equal incidence of RecurrentLaryngeal Nerve Palsy and wound infection that is 8% each.Conclusion: The most common post-operative complications are dysphagia and worsening of preexistingneurology an...

Research paper thumbnail of Clinical Outcome of Percutaneous Radiofrequency Rhizotomy for Trigeminal Neuralgia at a Tertiary Care Hospital

Pakistan Journal Of Neurological Surgery, 2019

Background: - Trigeminal neuralgia is a disease typically characterized by involuntary attacks of... more Background: - Trigeminal neuralgia is a disease typically characterized by involuntary attacks of lancinating pain in the distribution of the trigeminal nerve that are activated by non-noxious stimuli. Numerous anticonvulsants, either alone or in combination, remain the first choice in the medical treatment of trigeminal neuralgia.3If the disease becomes non responsive, there are numerous surgical options like micro vascular decompression or minimally invasive percutaneous lesioning of the trigeminal nerve, such as glycerol rhizolysis, Radiofrequency Rhizotomy, and balloon compression. Objective: - To determine efficacy of percutaneous Radiofrequency Rhizotomy for trigeminal neuralgia in terms of early pain relief in a tertiary care hospital. Methods: - 62 patients with refractory trigeminal neuralgia or lancinating, recurrent episodes of pain in the distribution of Ophthalmic (V1) and Mandibular (V3) branches of trigeminal nerve, not responsive to 6 months of conservative treatmen...

Research paper thumbnail of Outcome of Anterior Fusion Technique for Multilevel Cervical Spondylotic Myelopathy

Pakistan Journal Of Neurological Surgery, 2019

Objective: To asses’ surgical parameters, complications, clinical and radiological outcomes in ... more Objective: To asses’ surgical parameters, complications, clinical and radiological outcomes in the treatment of 2-, 3- and 4-levels Cervical Spondylotic Myelopathy . Methods: A total of 90 patients with 2-, 3- or 4-level CSM who underwent anterior decompression and fusion procedures between January 2017 and October 2018 were divided into three different groups, the 2-level group (65 patients), the 3-level group (20 patients) and the 4-level group (5 patients). The clinical and Radiographic outcomes like Neck Disability Index (NDI) score, hospital stay, blood loss, operation time, fusion rate, cervical lordosis, cervical range of motion (ROM), and complications were compared between different procedures. Results: At a minimum of 1-year follow-up, no statistical differences in NDI score, hospital stay, fusion rate and cervical lordosis were found among the 3 groups. However, the mean postoperative NDI score of the 4-level group was significantly higher than that in the other two gro...

Research paper thumbnail of Carbon monoxide poisoning with an atypical presentation on MRI: Case report and literature review

Annals of Medicine and Surgery