Muhammad Shah Zaib - Academia.edu (original) (raw)

Papers by Muhammad Shah Zaib

Journal of the Pakistan Medical Association, 2021

Objective: To determine the correlation of cardio-respiratory fitness with screen time and physic... more Objective: To determine the correlation of cardio-respiratory fitness with screen time and physical activity in healthy adolescents. Methods: An analytical cross sectional study was conducted in various schools of Rawalpindi and Islamabad from February 2019 till July 2019. Ethical approval was obtained by the ethical review committee of Foundation University Islamabad and higher authorities of school settings and written informed consent was obtained from all the participants. Non probability convenience sampling was done on N= 250 adolescents of ages 11-17 years including both genders. Participants were selected on the basis of inclusion and exclusion criteria. Cardiorespiratory fitness was evaluated through YMCA 3 min Step test, physical activity levels using physical activity questionnaire for adolescents (PAQ-A) and screen time via HELENA screen time Questionnaire. Data was entered and analysed on SPSS v.21. Quantitative variables were expressed as mean ± SD and Spearman’s Rank ...

Burning of wheat crop residue each year after harvesting is causing serious environmental degrada... more Burning of wheat crop residue each year after harvesting is causing serious environmental degradation and severely effecting the quality of air. In proposed research properties of Wheat Straw Ash (WSA) and utilization of WSA as an environmentally friendly material is presented. Tests such as Blaine Air Permeability, X-Ray Fluorescence (XRF), X-Ray Diffraction (XRD) and Scanning Electron Microscopy (SEM) shows that WSA contain amorphous silica and has the potential to be used as a pozzolanic material, which is capable to replace cement partially. To determine the optimum percentage of WSA as a partial replacement of cement, a series of tests are conducted on 10%, 20% and 30% replacement of WSA by weight of cement. Slump and compaction factor test show a decrease in workability as the content of ash is increased, it is due to the large water absorption capacity of ash. One of the major finding is the high-water absorption capacity of the WSA which helps on a long term to reduce the sh...

Circulation, 2020

Introduction: Chronic liver disease is known to be an important prognostic factor in determining ... more Introduction: Chronic liver disease is known to be an important prognostic factor in determining morbidity and mortality in preoperative risk assessment and mortality in general. Data are limited on outcomes in patients with infective endocarditis (IE) and comorbid concurrent liver cirrhosis. Objective of our study is to evaluate the clinical outcomes of patient with IE with and without underlying liver cirrhosis and determining in-hospital mortality and outcomes of interest i.e. renal failure, cardiogenic shock, hematologic (coagulopathy/thrombocytopenia) and hepatic complications (hepatic encephalopathy/hepatitis). Hypothesis: Liver Cirrhosis worsen clinical outcomes in patients with IE. Methods: Patients with principle diagnosis of IE with and without liver cirrhosis were identified by querying the Healthcare Cost and Utilization (HCUP) database, specifically, National Inpatient Sample for year 2013 and 2014 based on ICD9 codes. Results: During 2013 and 2014, a total of 17, 952 p...

Multimedia Systems, 2021

Cyber-bullying has been on the rise especially after the explosive widespread of various cyber-at... more Cyber-bullying has been on the rise especially after the explosive widespread of various cyber-attacks. Various types of techniques have been used to tackle cyber-bullying. These techniques focused primarily on data traffic for monitoring malicious activities. This research proposes a methodology where we can detect early Denial of service (DoS) and Distributed Denial of Service (DDoS) attacks. First, we formulate the problem in a practical scenario by comparing flow and non-flow-based datasets using Mann Whitney U statistical test. Flow and non-flow-based datasets and Artificial Neural Network (ANN) and Support Vector Machine (SVM) is used for classification. To keep original features, we use variance, correlation, ¾ quartile method to eliminate the unimportant features. The forward selection wrapper method for feature selection is used to find out the best features. To validate the proposed methodology, we take multiple DoS and DDoS single flow and validate it on 10%, 20%, 30%, 40%, and 50%. For validation, the experimental results show + 90% accuracy on the early 10% flow.

is a formative irregularity, coming about because of strange advancement of male outside genitali... more is a formative irregularity, coming about because of strange advancement of male outside genitalia bringing about the unusual position of outer meatus on the ventral side of penis rather than tip and ventrally insufficient prepuce with hooded skin on the dorsal surface of glans. Its most basic male outer genitalia deformity following cryptorchidism. Hypospadias is an overall male outside genitalia formative issue. Any outside manufactured simple of estrogen or different ecological poisons, toxins, pesticides, bug sprays and numerous otherrural and mechanical synthetic concoctions may act to disturb the endocrinological balance prompting hypospadias. Numerous qualities have been recognized yet these all demonstration additively and no single quality was discovered in charge of hypospadias. All elements which influence maternal wellbeing adversely are additionally connected with hypospadias. Adjusted eating regimen, evasion of any agrarian and mechanical synthetic concoctions and the superfluous hormonal enhancement may lessen the danger of hypospadias in numerous ladies. All around oversaw twin pregnancy and higher different incubation, diminishing the danger of placental inadequacy and its different indications by medicinal moves, pre-origination folate and multivitamin supplementation and evasion of any estrogenic nourishment like soya and astrict veggie lover diet which may contain exogenous estrogen may decrease the probability of hypospadias in young men of these ladies. Shirking of nuts, oilseeds, soya, oats, handled sustenances and bread which contains phytoestrogens may likewise lessen the hazard. Cruciferous vegetables like cabbage and citrus organic products decline the dimension of estrogen in the body by clearing it from liver and kidney thus ought to be taken. Truth be told, hypospadias is a multifactorial ecological and hereditary formative irregularity, which might be counteracted by previously mentioned ways and in an extensive extent of cases is sporadic.

A Network Interface (NI) architecture has been investigated and developed to optimize the run-tim... more A Network Interface (NI) architecture has been investigated and developed to optimize the run-time management of communication resources in Network on Chip-based manycore systems. The presented NI design also offers dedicated hardware support for reducing synchronization overhead and latencies between communicating software instances. The proposed concepts bring a throughput improvement of up to 38% when compared with state of the art methods via SystemC simulation and FPGA prototyping.

Main Group Chemistry, 2021

Metallo-elements have both pharmacological and toxic effects on plants, animals and humans. These... more Metallo-elements have both pharmacological and toxic effects on plants, animals and humans. These are considered as a major public health issue worldwide. In particular, heavy metals such as silver (Ag) and aluminum (Al) are environmentally widespread, and their relative toxicity can lead to numerous pathologies such as nephropathy, cancers, vascular and skin diseases. The goal of this study was to examine the behavioral effects of Ag and Al salts (i.e. Silver nitrate and Aluminum sulfate) on glutathione (GSH), a potent oxidant in biological mixtures. We also aimed to suggest mechanisms of action of thiolate complexed to these metallo-elements in competitive studies with Ellman’s reagent (5,5’-dithiobis(2-nitrobenzoic acid aka ESSE). By proton nuclear magnetic resonance (NMR) spectroscopy, detailed titrations were carried out for these metal thiols interactions in the presence of ESSE in order to elucidate first equilibrium and possible second equilibrium. We found by 1H NMR spectro...

Cureus, 2020

Hypothermia is not known as a common cause of acute pancreatitis, although there have been previo... more Hypothermia is not known as a common cause of acute pancreatitis, although there have been previously reported cases. Herein, we describe a 55-year-old man who presented with acute pancreatitis preceded by hypothermia in the absence of the more traditional causative factors, such as gallstones or alcohol consumption. On arrival to the emergency department, he was found to have a temperature of 84.3°F, consistent with moderate hypothermia, a blood pressure of 84/50 mmHg, and a heart rate of 60 bpm. Serum lipase and amylase levels were 2,225 and 980 U/L, respectively. A CT scan of the abdomen with intravenous (IV) contrast revealed peripancreatic fat stranding, consistent with the diagnosis. No evidence of gallstones or common bile duct dilatation was found. He had also developed acute kidney injury and lactic acidosis consistent with end-organ damage. After appropriate triage, he was admitted to the intensive care unit and supportively managed. An external rewarming strategy with IV fluids and antibiotics resulted in improvement in clinical status. Hypothermia can cause subtle changes in the microvasculature and production of free radicals, which can result in acute pancreatitis. It is important to determine the etiology so that appropriate treatment can be instituted with better outcomes.

Circulation, 2020

Introduction: Amyloidosis is a systemic illness that affects multiple organ systems including car... more Introduction: Amyloidosis is a systemic illness that affects multiple organ systems including cardiovascular, renal, gastrointestinal and pulmonary systems manifesting as restrictive cardiomyopathy, atrial and ventricular arrhythmias, nephrotic syndrome and gastrointestinal hemorrhage. Unknown is whether co-occurrence atrial fibrillation (AF), further worsens the outcomes in systemic amyloidosis. Hypothesis: Atrial Fibrillation worsen clinical outcomes in Amyloidosis. Methods: Patients with diagnosis of amyloidosis with and without concurrent AF were identified by querying the Healthcare Cost and Utilization (HCUP), specifically, National Inpatient Sample for year 2016 based on ICD10 codes. Results: During 2016, a total of 2997 patients were admitted with diagnosis of Amyloidosis, out of which 918 had concurrent AF. There was an increased risk of mortality (7.4% vs 5.6%), heart block (6.8% vs 2.8%), cardiogenic shock (5% vs 1.6%), placement of an ICD/CRT/PPM (14.5% vs 4.5%), renal f...

Cureus, 2020

Caroli disease is a rare congenital disorder resulting from the dilation of large intrahepatic bi... more Caroli disease is a rare congenital disorder resulting from the dilation of large intrahepatic bile ducts. Patients affected with Caroli disease are at increased risk of complications resulting from bile stasis and stone formation. We report the case of a 37-year-old woman with a past surgical history of cholecystectomy who presented to the emergency room with a chief complaint of abdominal pain and nausea. The pain was characteristic of acute pancreatitis but she was hemodynamically stable. Total bilirubin was 4.1 mg/dL with a direct fraction of 3.1 mg/dL, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were 850 IU/L and 1025 IU/L, respectively. Serum amylase and lipase were elevated at 581 IU/L and 1328 IU/L, respectively. CT scan of abdomen/pelvis without contrast showed common bile duct (CBD) measuring 1.6 cm with intrahepatic biliary system dilation and mild peripancreatic fat stranding. She was diagnosed with acute pancreatitis. On the second day, she developed a temperature of 99.6°F. Hepatitis immunity panel was negative for acute hepatitis. The patient was started on antibiotics (IV ciprofloxacin and metronidazole) for suspicion of acute cholangitis. Endoscopic retrograde cholangiopancreatography (ERCP) was done which showed mild dilated intrahepatic ducts and CBD dilation of 1.6 cm, and a choledochal cyst at CBD. Sphincterotomy was done and good bile drainage was reported. She was later discharged in a stable condition. Caroli disease affects males and females equally and most are diagnosed before the age of 30 years correlated with the onset of symptoms. By far, the most commonly reported symptom is acute cholangitis but pancreatitis occurs rarely. Recurrent bouts of infection lead to portal hypertension, fibrosis of the liver and ultimately end up with an orthotopic liver transplant (OLT). Regular follow-ups are important for disease surveillance and monitoring.

Journal of Structural Geology, 2020

This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Pakistan Journal of Phytopathology, Dec 31, 2014

Pakistan Journal of Phytopathology, Dec 31, 2014

Five plant extracts and five chemicals were evaluated against Rhzioctonia solani in lab condition... more Five plant extracts and five chemicals were evaluated against Rhzioctonia solani in lab conditions under completely randomized design (CRD). In plant extracts maximum inhibition against the pathogen expressed by Azadirachta indica (71%) followed by Allium sativum (56%), Eucalyptus camaldulensis (48%), Allium cepa (41%) and Peganum harmala (34%) while in chemicals Moncerene (75.8%) showed significant results followed by Topsin-M (62%), Copper oxychloride (53%), Score (45%) and Shankar (41%) as compared to control. In greenhouse different concentrations of Moncerene and Azadirachta indica alone and their combination were evaluated against the black scurf disease of potato. Combine treatment of Moncerene x A. indica showed highest eyes germination (78%) followed by Moncerene (58%) and Azadirachta indica (62%). Minimum disease incidence % and severity was recorded on combine treatment of Moncerene X Azadirachta indica (8%, 1%) followed by Moncerene (19%, 1.2%) and Azadirachta indica (20%, 1.4%) respectively. Under field conditions same combine treatment of Moncerence X Azadirachta indica showed highest eyes germination (78%) with minimum disease incidence (8%) and severity (1%) as compared to Moncerene (56.6%, 12.4%, 2.4%0) and Azadirachta indica (51%, 12.2%, 2.4%) respectively. Randomized complete block design (RCBD) was applied in field conditions. All experiments were conducted in

Networks on Chip (NoC) come along with increased complexity from the implementation and managemen... more Networks on Chip (NoC) come along with increased complexity from the implementation and management perspective. This leads to higher energy consumption and programming complexity of NoC architectures. This work introduces communication aware programming to address communication resource management and efficient programming of NoC architectures. A programming interface is introduced to express communication requirements at the language level. These requirements are evaluated by an operating system component, which configures the communication hardware accordingly. The proposed concept enables an intuitive use of NoC features like end-to-end connections and Direct Memory Access (DMA). The presented results show that communication aware programming can improve performance and energy consumption.

World journal of plastic surgery, 2015

Burn wound infections carry considerable mortality and morbidity amongst burn injury victims who ... more Burn wound infections carry considerable mortality and morbidity amongst burn injury victims who have been successfully rescued through the initial resuscitation. This study assessed the prevalent microrganisms causing burn wound infections among hospitalized patients; their susceptibility pattern to commonly used antibiotics; and the frequency of infections with respect to the duration of the burn wounds. This study was carried out at Burn Care Centre, Pakistan Institute of Medical Sciences (PIMS), Islamabad, Pakistan over a period of two years (i.e. from June 2010 to May 2012). The study included all wound-culture-positive patients of either gender and all ages, who had sustained deep burns and underwent definitive management with wound excisions and skin auto-grafting. Patients with negative cultures of the wounds were excluded. Tissue specimens for culture and sensitivity were collected from burn wounds using standard collection techniques and analyzed at microbiological laborat...

2012 IEEE 26th International Parallel and Distributed Processing Symposium Workshops & PhD Forum, 2012

ABSTRACT Networks-on-Chip have shown their scalability for future many-core systems on chip. In r... more ABSTRACT Networks-on-Chip have shown their scalability for future many-core systems on chip. In real world scenarios, concurrent applications with different QoS requirements affect each other through overlapping communication. Therefore computation resources may not be efficiently utilized because the required communication resources are already occupied. Hence, an efficient resource management strategy is required that ensures fair sharing of communication resources between applications. Decentralized strategies provide better scalability in many-core systems. In this paper, we propose a hardware supported decentralized NoC resource management strategy. Our concept enables to define NoC regions through decentralized reconfigurable resource management policies. It offers improved performance and communication resource allocation within the regions. The proposed concept is investigated through simulation of real world application scenarios. The simulation results highlight the performance benefit within the region and the increased probability for successful reservation of communication resources. Implementation results show the low area overhead of the proposed hardware support.

22nd International Conference on Field Programmable Logic and Applications (FPL), 2012

Manycore System-on-Chip include an increasing amount of processing elements and have become an im... more Manycore System-on-Chip include an increasing amount of processing elements and have become an important research topic for improvements of both hardware and software. While research can be conducted using system simulators, prototyping requires a variety of components and is very time consuming. With the Open Tiled Manycore System-on-Chip (OpTiMSoC) we aim at building such an environment for use in our and other research projects as prototyping platform. This paper describes the project goals and aspects of OpTiMSoC and summarizes the current status and ideas.

2013 IEEE International Symposium on Parallel & Distributed Processing, Workshops and Phd Forum, 2013

ABSTRACT Managing future many-core architectures with hundreds of cores, running multiple applica... more ABSTRACT Managing future many-core architectures with hundreds of cores, running multiple applications in parallel, is very challenging. One of the major reasons is the communication overhead required to handle such a large system. Distributed management is proposed to reduce this overhead. The architecture is divided into regions which are managed separately. The instance managing the region and the applications running within the regions need to collect data for various reasons from time to time, e.g., to collect data for proper mapping decision, to synchronize tasks or to aggregate computation results. In this work, we propose and investigate different strategies for adaptive data collection in meshed Networks on Chip. The mechanisms can be used to collect data within regions, which are defined during run-time in respect of size and position. The mechanisms are investigated while considering delay, NoC utilization and implementation costs. The results show that the selection of the used mechanism depends on the requirements. Synthesis results compare area overhead, timing impact and energy consumption.

Journal of the Pakistan Medical Association, 2021

Objective: To determine the correlation of cardio-respiratory fitness with screen time and physic... more Objective: To determine the correlation of cardio-respiratory fitness with screen time and physical activity in healthy adolescents. Methods: An analytical cross sectional study was conducted in various schools of Rawalpindi and Islamabad from February 2019 till July 2019. Ethical approval was obtained by the ethical review committee of Foundation University Islamabad and higher authorities of school settings and written informed consent was obtained from all the participants. Non probability convenience sampling was done on N= 250 adolescents of ages 11-17 years including both genders. Participants were selected on the basis of inclusion and exclusion criteria. Cardiorespiratory fitness was evaluated through YMCA 3 min Step test, physical activity levels using physical activity questionnaire for adolescents (PAQ-A) and screen time via HELENA screen time Questionnaire. Data was entered and analysed on SPSS v.21. Quantitative variables were expressed as mean ± SD and Spearman’s Rank ...

Burning of wheat crop residue each year after harvesting is causing serious environmental degrada... more Burning of wheat crop residue each year after harvesting is causing serious environmental degradation and severely effecting the quality of air. In proposed research properties of Wheat Straw Ash (WSA) and utilization of WSA as an environmentally friendly material is presented. Tests such as Blaine Air Permeability, X-Ray Fluorescence (XRF), X-Ray Diffraction (XRD) and Scanning Electron Microscopy (SEM) shows that WSA contain amorphous silica and has the potential to be used as a pozzolanic material, which is capable to replace cement partially. To determine the optimum percentage of WSA as a partial replacement of cement, a series of tests are conducted on 10%, 20% and 30% replacement of WSA by weight of cement. Slump and compaction factor test show a decrease in workability as the content of ash is increased, it is due to the large water absorption capacity of ash. One of the major finding is the high-water absorption capacity of the WSA which helps on a long term to reduce the sh...

Circulation, 2020

Introduction: Chronic liver disease is known to be an important prognostic factor in determining ... more Introduction: Chronic liver disease is known to be an important prognostic factor in determining morbidity and mortality in preoperative risk assessment and mortality in general. Data are limited on outcomes in patients with infective endocarditis (IE) and comorbid concurrent liver cirrhosis. Objective of our study is to evaluate the clinical outcomes of patient with IE with and without underlying liver cirrhosis and determining in-hospital mortality and outcomes of interest i.e. renal failure, cardiogenic shock, hematologic (coagulopathy/thrombocytopenia) and hepatic complications (hepatic encephalopathy/hepatitis). Hypothesis: Liver Cirrhosis worsen clinical outcomes in patients with IE. Methods: Patients with principle diagnosis of IE with and without liver cirrhosis were identified by querying the Healthcare Cost and Utilization (HCUP) database, specifically, National Inpatient Sample for year 2013 and 2014 based on ICD9 codes. Results: During 2013 and 2014, a total of 17, 952 p...

Multimedia Systems, 2021

Cyber-bullying has been on the rise especially after the explosive widespread of various cyber-at... more Cyber-bullying has been on the rise especially after the explosive widespread of various cyber-attacks. Various types of techniques have been used to tackle cyber-bullying. These techniques focused primarily on data traffic for monitoring malicious activities. This research proposes a methodology where we can detect early Denial of service (DoS) and Distributed Denial of Service (DDoS) attacks. First, we formulate the problem in a practical scenario by comparing flow and non-flow-based datasets using Mann Whitney U statistical test. Flow and non-flow-based datasets and Artificial Neural Network (ANN) and Support Vector Machine (SVM) is used for classification. To keep original features, we use variance, correlation, ¾ quartile method to eliminate the unimportant features. The forward selection wrapper method for feature selection is used to find out the best features. To validate the proposed methodology, we take multiple DoS and DDoS single flow and validate it on 10%, 20%, 30%, 40%, and 50%. For validation, the experimental results show + 90% accuracy on the early 10% flow.

is a formative irregularity, coming about because of strange advancement of male outside genitali... more is a formative irregularity, coming about because of strange advancement of male outside genitalia bringing about the unusual position of outer meatus on the ventral side of penis rather than tip and ventrally insufficient prepuce with hooded skin on the dorsal surface of glans. Its most basic male outer genitalia deformity following cryptorchidism. Hypospadias is an overall male outside genitalia formative issue. Any outside manufactured simple of estrogen or different ecological poisons, toxins, pesticides, bug sprays and numerous otherrural and mechanical synthetic concoctions may act to disturb the endocrinological balance prompting hypospadias. Numerous qualities have been recognized yet these all demonstration additively and no single quality was discovered in charge of hypospadias. All elements which influence maternal wellbeing adversely are additionally connected with hypospadias. Adjusted eating regimen, evasion of any agrarian and mechanical synthetic concoctions and the superfluous hormonal enhancement may lessen the danger of hypospadias in numerous ladies. All around oversaw twin pregnancy and higher different incubation, diminishing the danger of placental inadequacy and its different indications by medicinal moves, pre-origination folate and multivitamin supplementation and evasion of any estrogenic nourishment like soya and astrict veggie lover diet which may contain exogenous estrogen may decrease the probability of hypospadias in young men of these ladies. Shirking of nuts, oilseeds, soya, oats, handled sustenances and bread which contains phytoestrogens may likewise lessen the hazard. Cruciferous vegetables like cabbage and citrus organic products decline the dimension of estrogen in the body by clearing it from liver and kidney thus ought to be taken. Truth be told, hypospadias is a multifactorial ecological and hereditary formative irregularity, which might be counteracted by previously mentioned ways and in an extensive extent of cases is sporadic.

A Network Interface (NI) architecture has been investigated and developed to optimize the run-tim... more A Network Interface (NI) architecture has been investigated and developed to optimize the run-time management of communication resources in Network on Chip-based manycore systems. The presented NI design also offers dedicated hardware support for reducing synchronization overhead and latencies between communicating software instances. The proposed concepts bring a throughput improvement of up to 38% when compared with state of the art methods via SystemC simulation and FPGA prototyping.

Main Group Chemistry, 2021

Metallo-elements have both pharmacological and toxic effects on plants, animals and humans. These... more Metallo-elements have both pharmacological and toxic effects on plants, animals and humans. These are considered as a major public health issue worldwide. In particular, heavy metals such as silver (Ag) and aluminum (Al) are environmentally widespread, and their relative toxicity can lead to numerous pathologies such as nephropathy, cancers, vascular and skin diseases. The goal of this study was to examine the behavioral effects of Ag and Al salts (i.e. Silver nitrate and Aluminum sulfate) on glutathione (GSH), a potent oxidant in biological mixtures. We also aimed to suggest mechanisms of action of thiolate complexed to these metallo-elements in competitive studies with Ellman’s reagent (5,5’-dithiobis(2-nitrobenzoic acid aka ESSE). By proton nuclear magnetic resonance (NMR) spectroscopy, detailed titrations were carried out for these metal thiols interactions in the presence of ESSE in order to elucidate first equilibrium and possible second equilibrium. We found by 1H NMR spectro...

Cureus, 2020

Hypothermia is not known as a common cause of acute pancreatitis, although there have been previo... more Hypothermia is not known as a common cause of acute pancreatitis, although there have been previously reported cases. Herein, we describe a 55-year-old man who presented with acute pancreatitis preceded by hypothermia in the absence of the more traditional causative factors, such as gallstones or alcohol consumption. On arrival to the emergency department, he was found to have a temperature of 84.3°F, consistent with moderate hypothermia, a blood pressure of 84/50 mmHg, and a heart rate of 60 bpm. Serum lipase and amylase levels were 2,225 and 980 U/L, respectively. A CT scan of the abdomen with intravenous (IV) contrast revealed peripancreatic fat stranding, consistent with the diagnosis. No evidence of gallstones or common bile duct dilatation was found. He had also developed acute kidney injury and lactic acidosis consistent with end-organ damage. After appropriate triage, he was admitted to the intensive care unit and supportively managed. An external rewarming strategy with IV fluids and antibiotics resulted in improvement in clinical status. Hypothermia can cause subtle changes in the microvasculature and production of free radicals, which can result in acute pancreatitis. It is important to determine the etiology so that appropriate treatment can be instituted with better outcomes.

Circulation, 2020

Introduction: Amyloidosis is a systemic illness that affects multiple organ systems including car... more Introduction: Amyloidosis is a systemic illness that affects multiple organ systems including cardiovascular, renal, gastrointestinal and pulmonary systems manifesting as restrictive cardiomyopathy, atrial and ventricular arrhythmias, nephrotic syndrome and gastrointestinal hemorrhage. Unknown is whether co-occurrence atrial fibrillation (AF), further worsens the outcomes in systemic amyloidosis. Hypothesis: Atrial Fibrillation worsen clinical outcomes in Amyloidosis. Methods: Patients with diagnosis of amyloidosis with and without concurrent AF were identified by querying the Healthcare Cost and Utilization (HCUP), specifically, National Inpatient Sample for year 2016 based on ICD10 codes. Results: During 2016, a total of 2997 patients were admitted with diagnosis of Amyloidosis, out of which 918 had concurrent AF. There was an increased risk of mortality (7.4% vs 5.6%), heart block (6.8% vs 2.8%), cardiogenic shock (5% vs 1.6%), placement of an ICD/CRT/PPM (14.5% vs 4.5%), renal f...

Cureus, 2020

Caroli disease is a rare congenital disorder resulting from the dilation of large intrahepatic bi... more Caroli disease is a rare congenital disorder resulting from the dilation of large intrahepatic bile ducts. Patients affected with Caroli disease are at increased risk of complications resulting from bile stasis and stone formation. We report the case of a 37-year-old woman with a past surgical history of cholecystectomy who presented to the emergency room with a chief complaint of abdominal pain and nausea. The pain was characteristic of acute pancreatitis but she was hemodynamically stable. Total bilirubin was 4.1 mg/dL with a direct fraction of 3.1 mg/dL, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were 850 IU/L and 1025 IU/L, respectively. Serum amylase and lipase were elevated at 581 IU/L and 1328 IU/L, respectively. CT scan of abdomen/pelvis without contrast showed common bile duct (CBD) measuring 1.6 cm with intrahepatic biliary system dilation and mild peripancreatic fat stranding. She was diagnosed with acute pancreatitis. On the second day, she developed a temperature of 99.6°F. Hepatitis immunity panel was negative for acute hepatitis. The patient was started on antibiotics (IV ciprofloxacin and metronidazole) for suspicion of acute cholangitis. Endoscopic retrograde cholangiopancreatography (ERCP) was done which showed mild dilated intrahepatic ducts and CBD dilation of 1.6 cm, and a choledochal cyst at CBD. Sphincterotomy was done and good bile drainage was reported. She was later discharged in a stable condition. Caroli disease affects males and females equally and most are diagnosed before the age of 30 years correlated with the onset of symptoms. By far, the most commonly reported symptom is acute cholangitis but pancreatitis occurs rarely. Recurrent bouts of infection lead to portal hypertension, fibrosis of the liver and ultimately end up with an orthotopic liver transplant (OLT). Regular follow-ups are important for disease surveillance and monitoring.

Journal of Structural Geology, 2020

This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Pakistan Journal of Phytopathology, Dec 31, 2014

Pakistan Journal of Phytopathology, Dec 31, 2014

Five plant extracts and five chemicals were evaluated against Rhzioctonia solani in lab condition... more Five plant extracts and five chemicals were evaluated against Rhzioctonia solani in lab conditions under completely randomized design (CRD). In plant extracts maximum inhibition against the pathogen expressed by Azadirachta indica (71%) followed by Allium sativum (56%), Eucalyptus camaldulensis (48%), Allium cepa (41%) and Peganum harmala (34%) while in chemicals Moncerene (75.8%) showed significant results followed by Topsin-M (62%), Copper oxychloride (53%), Score (45%) and Shankar (41%) as compared to control. In greenhouse different concentrations of Moncerene and Azadirachta indica alone and their combination were evaluated against the black scurf disease of potato. Combine treatment of Moncerene x A. indica showed highest eyes germination (78%) followed by Moncerene (58%) and Azadirachta indica (62%). Minimum disease incidence % and severity was recorded on combine treatment of Moncerene X Azadirachta indica (8%, 1%) followed by Moncerene (19%, 1.2%) and Azadirachta indica (20%, 1.4%) respectively. Under field conditions same combine treatment of Moncerence X Azadirachta indica showed highest eyes germination (78%) with minimum disease incidence (8%) and severity (1%) as compared to Moncerene (56.6%, 12.4%, 2.4%0) and Azadirachta indica (51%, 12.2%, 2.4%) respectively. Randomized complete block design (RCBD) was applied in field conditions. All experiments were conducted in

Networks on Chip (NoC) come along with increased complexity from the implementation and managemen... more Networks on Chip (NoC) come along with increased complexity from the implementation and management perspective. This leads to higher energy consumption and programming complexity of NoC architectures. This work introduces communication aware programming to address communication resource management and efficient programming of NoC architectures. A programming interface is introduced to express communication requirements at the language level. These requirements are evaluated by an operating system component, which configures the communication hardware accordingly. The proposed concept enables an intuitive use of NoC features like end-to-end connections and Direct Memory Access (DMA). The presented results show that communication aware programming can improve performance and energy consumption.

World journal of plastic surgery, 2015

Burn wound infections carry considerable mortality and morbidity amongst burn injury victims who ... more Burn wound infections carry considerable mortality and morbidity amongst burn injury victims who have been successfully rescued through the initial resuscitation. This study assessed the prevalent microrganisms causing burn wound infections among hospitalized patients; their susceptibility pattern to commonly used antibiotics; and the frequency of infections with respect to the duration of the burn wounds. This study was carried out at Burn Care Centre, Pakistan Institute of Medical Sciences (PIMS), Islamabad, Pakistan over a period of two years (i.e. from June 2010 to May 2012). The study included all wound-culture-positive patients of either gender and all ages, who had sustained deep burns and underwent definitive management with wound excisions and skin auto-grafting. Patients with negative cultures of the wounds were excluded. Tissue specimens for culture and sensitivity were collected from burn wounds using standard collection techniques and analyzed at microbiological laborat...

2012 IEEE 26th International Parallel and Distributed Processing Symposium Workshops & PhD Forum, 2012

ABSTRACT Networks-on-Chip have shown their scalability for future many-core systems on chip. In r... more ABSTRACT Networks-on-Chip have shown their scalability for future many-core systems on chip. In real world scenarios, concurrent applications with different QoS requirements affect each other through overlapping communication. Therefore computation resources may not be efficiently utilized because the required communication resources are already occupied. Hence, an efficient resource management strategy is required that ensures fair sharing of communication resources between applications. Decentralized strategies provide better scalability in many-core systems. In this paper, we propose a hardware supported decentralized NoC resource management strategy. Our concept enables to define NoC regions through decentralized reconfigurable resource management policies. It offers improved performance and communication resource allocation within the regions. The proposed concept is investigated through simulation of real world application scenarios. The simulation results highlight the performance benefit within the region and the increased probability for successful reservation of communication resources. Implementation results show the low area overhead of the proposed hardware support.

22nd International Conference on Field Programmable Logic and Applications (FPL), 2012

Manycore System-on-Chip include an increasing amount of processing elements and have become an im... more Manycore System-on-Chip include an increasing amount of processing elements and have become an important research topic for improvements of both hardware and software. While research can be conducted using system simulators, prototyping requires a variety of components and is very time consuming. With the Open Tiled Manycore System-on-Chip (OpTiMSoC) we aim at building such an environment for use in our and other research projects as prototyping platform. This paper describes the project goals and aspects of OpTiMSoC and summarizes the current status and ideas.

2013 IEEE International Symposium on Parallel & Distributed Processing, Workshops and Phd Forum, 2013

ABSTRACT Managing future many-core architectures with hundreds of cores, running multiple applica... more ABSTRACT Managing future many-core architectures with hundreds of cores, running multiple applications in parallel, is very challenging. One of the major reasons is the communication overhead required to handle such a large system. Distributed management is proposed to reduce this overhead. The architecture is divided into regions which are managed separately. The instance managing the region and the applications running within the regions need to collect data for various reasons from time to time, e.g., to collect data for proper mapping decision, to synchronize tasks or to aggregate computation results. In this work, we propose and investigate different strategies for adaptive data collection in meshed Networks on Chip. The mechanisms can be used to collect data within regions, which are defined during run-time in respect of size and position. The mechanisms are investigated while considering delay, NoC utilization and implementation costs. The results show that the selection of the used mechanism depends on the requirements. Synthesis results compare area overhead, timing impact and energy consumption.