Muhammet Ali Beyoglu - Academia.edu (original) (raw)

Papers by Muhammet Ali Beyoglu

Archives of current medical research (ACMR), Sep 29, 2022

Background: Primary Spontaneous Pneumothorax is a disease with a frequent recurrence rate. The un... more Background: Primary Spontaneous Pneumothorax is a disease with a frequent recurrence rate. The uniportal videothoracoscopic surgery approach is the standard treatment for air leak and recurrence prevention. In common practice, apical pleurectomy is used after apical wedge resection. Our study aims to examine the results, especially the recurrence rate, of the lateral pleurectomy and apical pleural abrasion combination technique applied as an alternative to this technique. Methods: A total of 50 patients who underwent uniportal videothoracoscopic surgery for primary spontaneous pneumothorax between November 2018 and May 2021 were included in the study. The follow-up period for recurrence of the patients was 12-42 months. Age, gender, pneumothorax side, operation indication, Body Mass Index, smoking history, incision length and location, air leakage and tube thoracostomy duration, Verbal Numeric Pain Scores, post-operative length of hospital stay, complications, and recurrence data were recorded. Results: Of the 50 patients, 44 (88%) were male, and 6 (12%) were female, with a mean age of 22.3±5.9 years. Surgery was performed from the existing drain site in 32 (64%) cases and the former drain scar in 11 (22%) cases. The mean duration of tube thoracostomy was 2.7±0.97 days, and the mean length of hospital stay was 3.6±0.89 days. Complications developed in 2 (4%) cases, and recurrence was observed in 2 (4%) cases. Conclusions: Lateral pleurectomy with the apical pleural abrasion technique is easy to apply and reduces the possibility of undesired hemorrhagic drainage. We believe that the lateral pleurectomy technique is safe, easily applicable, and less risky in terms of hemorrhage.

Experimental and Clinical Transplantation, Apr 29, 2021

The pandemic of SARS-CoV-2, known as COVID-19, has continued to show its effect all over the worl... more The pandemic of SARS-CoV-2, known as COVID-19, has continued to show its effect all over the world. The clinical course of the disease in solid-organ transplant recipients is a matter of concern. Lung transplant recipients also demonstrate special features because the graft encounters the COVID-19 pathogen directly as a result of inhalation, and the lungs are the most important organs affected by the disease. We shared the development process of acute rejection followed by rapid progression of chronic lung allograft dysfunction after COVID-19 in a recipient who was followed-up in the fifth year after lung transplant.

Journal of Cancer Research and Therapeutics, 2023

Erciyes medical journal, 2021

Lung transplantation significantly improves the quality of life and survival in end-stage lung di... more Lung transplantation significantly improves the quality of life and survival in end-stage lung diseases. Successful lung transplantation has been performed only for 35 years. Despite the increase in the number of lung transplants in recent years, the difference between potential recipient candidates and the number of lung transplants increases further. In Turkey, which has significant experience in other solid-organ transplantations, lung transplantation has only been routinely applied in the last decade. In this review, the history of lung transplantation in Turkey, current situation, and prospects will be discussed.

Experimental and Clinical Transplantation, Oct 18, 2022

Transplantation Proceedings, Sep 1, 2022

Journal of Heart and Lung Transplantation, Apr 1, 2021

Turkish Journal of Thoracic and Cardiovascular Surgery, 2022

Bu çalışmada açık kalp cerrahisi sonrası median sternotomiye bağlı sternal dehisens ve mediastini... more Bu çalışmada açık kalp cerrahisi sonrası median sternotomiye bağlı sternal dehisens ve mediastinit tedavisinde kullandığımız yöntemlerin sonuçları değerlendirildi. Ça lış m a pla nı: Temmuz 2014-Mart 2019 arasında kalp cerrahisi sonrası sternal dehisens ve mediastinit gelişen toplam 13 hasta (8 erkek, 5 kadın; ort. yaş: 60.3±2.9 yıl; dağılım 33-74 yıl) retrospektif olarak incelendi. Hasta verileri hastane kayıtlarından elde edildi. Bul gu lar: İşlem öncesinde üç olguda Robiscek tekniği ile rekonstrüksiyon yapılırken, bir olguda da debridman sonrası konvansiyonel yeniden telleme tekniği uygulandı. Bir olgu dışında tüm olgularda sternal pürülan akıntı mevcuttu (n=12, %92). Dört olgu dışında tüm olguların sternumunda en az iki fraktür hattı mevcuttu (n=9, %69). İşlem öncesinde olgulara 1 ila 10 seans (medyan=4) vakum yardımlı kapama tedavisi uygulandı. Sternal fiksasyon için en az iki adet bar karşılıklı kaburgalar arasına yerleştirildi. Üç olgu dışında tüm olgulara sternal boşluğa transdiyafragmatik çekilen omentum yerleştirildi. İki olguda seroma ve lokal enfeksiyon nüksü (n=2, %15.3) ve bir olguda insizyonel herni (n=1, %7.6) gelişti. Olguların tümünde toraks stabilizasyonu başarı ile sağlandı. So nuç: Ameliyat öncesi dönemde kültür negatif oluncaya kadar uygulanan vakum yardımlı kapatma tedavisi ve ameliyat sırasında sternal boşluğa transdiyafragmatik omentum uygulanması ile desteklenen STRATOS sisteminin kullanıldığı sternal rekonstrüksiyon ile komplike sternal dehisens olgularında toraks stabilizasyonu başarı ile sağlanabilir.

Transplantation Proceedings, Oct 1, 2022

Transplantation Proceedings, Jul 1, 2022

The vaccines developed against Severe acute respiratory syndrome coronavirus type 2 are seen as t... more The vaccines developed against Severe acute respiratory syndrome coronavirus type 2 are seen as the most crucial weapon in controlling the epidemic. It has been reported in early-stage vaccine studies that vaccines provide up to 95% protection against severe disease and mortality, even in the absence of symptomatic infection. Reports on vaccine breakthrough infections that developed after widespread vaccination are available in the literature. In addition to the general population, the course of vaccine breakthrough infections in immunocompromised patients is a matter of concern. This case report aimed to define severe COVID-19 developing in a lung recipient who received three doses of inactivated virus vaccine.

Saudi Medical Journal, Oct 1, 2022

‫ا‬ ‫أيضً‬ ‫كان‬ ‫)؛‬p=0.006(‫املنببني‬ ‫غير‬ ‫باملرضى‬ ‫مقارنة‬ ‫املركزة‬ ‫العناية‬ ‫لوحدة‬ ‫وال... more ‫ا‬ ‫أيضً‬ ‫كان‬ ‫)؛‬p=0.006(‫املنببني‬ ‫غير‬ ‫باملرضى‬ ‫مقارنة‬ ‫املركزة‬ ‫العناية‬ ‫لوحدة‬ ‫والوفيات‬ MV ‫الحتياج‬ ‫العتبة‬ ‫قيم‬ ‫كانت‬ .)p=0.009(‫الناجني‬ ‫غير‬ ‫في‬ ‫أقل‬ ‫اخلصائص‬ ‫لتحليل‬ ‫ًا‬ ‫وفق‬ ،)p=0.006(‫572.3مم‬ ‫و‬)p=0.004(‫53.3مم‬ ‫املجموعة‬ ‫لدى‬ ‫كان‬ ‫التنبؤية.‬ ‫القدرة‬ ‫لتقييم‬ ‫واملستخدمه‬ ‫ِل‬ ‫للمستقب‬ ‫التشغيله‬ ‫كان‬ .)p=0.026(‫الليمفاوية‬ ‫اخلاليا‬ ‫إلى‬ ‫العدالت‬ ‫من‬ ‫أكبر‬ ‫نسبة‬ ‫الناجية‬ ‫غير‬ ‫الليمفاوية‬ ‫اخلاليا‬ ‫إلى‬ ‫العدالت‬ ‫ونسبة‬ ،)p=0.017(‫املطلق‬ ‫العدالت‬ ‫عدد‬ ‫الذين‬ ‫املرضى‬ ‫بني‬ ‫أعلى‬)p=0.027(‫إنترلوكني-6‬ ‫ومستويات‬ ،)p=0.010(‫املنببني.‬ ‫غير‬ ‫باملرضى‬ ‫مقارنة‬ MV ‫إلى‬ ‫يحتاجون‬ .DT ‫قياسات‬ ‫من‬ MV ‫ومتطلبات‬ ‫الوفيات‬ ‫مبتطلبات‬ ‫التنبؤ‬ ‫ميكن‬ ‫اخلالصة:‬ ‫التصوير‬ ‫تقييم‬ ‫عند‬ ‫عالية‬ ‫ملخاطر‬ ‫املعرضني‬ ‫املرضى‬ ‫حتديد‬ DT ‫يسهل‬ ‫أن‬ ‫ميكن‬ ‫املركزة.‬ ‫العناية‬ ‫لوحدة‬ ‫الدخول‬ ‫عند‬ ‫احملوسب‬ ‫املقطعي‬ Objectives: To investigate the value of measuring the diaphragm thickness)DT(on thorax computed tomography)CT(at intensive care unit)ICU(admission for predicting intubation requirement and mortality among COVID-19 patients. Methods: This study was carried out in Ankara City Hospital, Ankara, Turkey, from September 2020 to January 2021, with 94 critical COVID-19 patients. The patients' demographic characteristics, laboratory parameters, DT measurements, mechanical ventilation)MV(requirements, and mortality statuses were retrospectively screened. The relationships between DT on initial CT, MV requirement, and mortality were investigated. Original Article Results: Diaphragm thickness was lower in patients who required intubation after ICU admission than in non-intubated patients)p=0.006(; it was also lower in non-survivors)p=0.009(. The threshold values for MV need was 3.35 mm)p=0.004(and 3.275 mm for mortality)p=0.006(, according to the receiver operating characteristic analysis used to assess the predictive potential of DT. The non-survivor group had a greater neutrophil-to-lymphocyte ratio)p=0.026(. Absolute neutrophil count)p=0.017(, neutrophil-to-lymphocyte ratio)p=0.010(, and interleukin-6 levels)p=0.027(were higher among patients requiring MV than among non-intubated patients. Conclusion: Mortality and MV requirements can be predicted from DT measurements. Diaphragm thickness can facilitate the identification of high-risk patients on CT evaluation at ICU admission.

Transplant Infectious Disease, Aug 16, 2021

BackgroundCoronavirus disease 2019 (COVID‐19) is a global health problem. However, the course of ... more BackgroundCoronavirus disease 2019 (COVID‐19) is a global health problem. However, the course of this disease in immunosuppressed patients remains unknown. This study aimed to describe the course of COVID‐19 infection and its effects on lung transplant recipients.MethodsThis was a single‐center, retrospective, observational study. The recipients with suspicious symptoms and/or a contact history with infected individuals were diagnosed with COVID‐19 by performing a reverse transcription‐polymerase chain reaction (RT‐PCR) test using samples obtained from the nasopharynx swabs or bronchial lavage. We classified the patients into mild, moderate, and high severity groups according to their clinical conditions. In patients with positive RT‐PCR results, cell cycle inhibitor drugs were withdrawn, while steroids were maintained at the same level as in patients without clinical deterioration.ResultsOf the seven recipients diagnosed with COVID‐19 infection, one experienced a re‐infection. Each recipient had at least one comorbidity. Smell disorder (12.5%), cough/dyspnea (37%), and fever/chills/shivering (37%) were the most frequent symptoms. The mean follow‐up time after infection was 108 days. No deaths were recorded due to COVID‐19; however, the pulmonary function test values of two recipients were decreased during subsequent follow‐ups.ConclusionIn our small group of transplant recipients with COVID‐19, there were two cases of pulmonary function deterioration and a case of re‐infection, and no recipient died. It is suggested that steroid therapy should be initiated in the early period in patients with pulmonary opacities.

The Eurasian Journal of Medicine, Mar 2, 2023

Medicine Science | International Medical Journal, 2022

In recent years, Video-assisted Thoracoscopic Surgery (VATS) has caused many changes in thoracic ... more In recent years, Video-assisted Thoracoscopic Surgery (VATS) has caused many changes in thoracic surgery practice. This study aimed to analyze the results of early VATS surgery in patients with empyema. Thirty-two cases of empyema who underwent VATS drainage, debridement, pleural pouch jointing, and partial decortication between November 2018 and June 2022 were included in the study retrospectively. The cases were examined for demographic information, the duration of symptoms, the stages of empyema, treatment outcomes, and complications. Twenty-three (79.9%) cases were male, 9 (28.1%) were female, and the mean age was 46.4±19.9. Preoperative symptom duration was 2.68±1.46 weeks. 28 (87.5%) cases were in stage 2 and 4 (12.5%) cases were in stage 3 empyema. A single incision VATS was performed in 23 (71.9%) cases, and double incision VATS was performed in 9 (28.1%) cases. Postoperative hospital stay was 12.1±3.3 days. Acceptable symptomatic and radiological improvement was observed in 28 (87.5%) cases after VATS. Pleural decortication with thoracotomy was used in four (12.5%) cases of stage 3 empyema. In cases of stage 2 empyema, which occurs within the first four weeks of the onset of symptoms, the VATS procedure with drainage, debridement, pouch jointing, and partial decortication provides curative results. We recommend evaluating VATS as the first-line therapy in treating early-stage empyema.

Kocatepe Tıp Dergisi, Oct 17, 2022

Spontan Pnömomediastinum (SPM), kendiliğinden veya tetikleyici faktörlerin etkisi ile oluşan alve... more Spontan Pnömomediastinum (SPM), kendiliğinden veya tetikleyici faktörlerin etkisi ile oluşan alveoler rüptür sonucu havanın trakeobronşial ağaç komşuluğu yolu ile mediastende birikimi ile oluşan nadir görülen bir hastalıktır. Bu çalışmanın amacı, spontan pnömomediasten tanı ve tedavisindeki deneyimlerimizi bildirmektir. GEREÇ VE YÖNTEM: 3.5 yıllık süreçte SPM tanısı ile tedavi edilen 17 hasta retrospektif olarak çalışmaya alındı. Olguların; yaş, cinsiyet, sigara kullanımı, ek hastalık durumu, klinik prezentasyonları, radyolojik görüntüleme, tedavi süreçleri ve nüks durumları incelendi. Sekonder pnömomediasten olguları çalışmaya alınmadı. BULGULAR: SPM olgularının 14'ü erkek ve 3'ü kadın hastaydı. Ortalama yaş 19.2 ±2.8 ve ortalama BMI 18.5 ±6.3 kg/m2 olarak bulundu. SPM oluşumu için tetikleyici faktör 13 (%76.5) olguda bulunmaktaydı. 4 (%23.5) olguda astım tanısı mevcuttu. 9 (%52.9) olgu sigara kullanmaktaydı. En sık görülen semptom 14 (%82.4) olguyla göğüs ağrısıydı. Subkutan amfizem 5 (%29.4) ve Hamman bulgusu 2 (%11.8) olguda vardı ve Toraks tomografisinde 3 (%17.6) olguda Macklin effect tespit edildi. Olguların hastanedeki yatış süresi ise ortalama 4.5 ±2 gündü. Olguların hiçbirisine fiberoptik bronkoskopi, üst GIS endoskopi ve pretrakeal fasya açılması yada mediastene drenaj katateri yerleştirilmesi gibi girişimsel işlem uygulanmadı. Antibiyoterapi oranları incelendiğinde ise 13 (%76.5) olguya antibiyoterapi verilmediği, ve hiçbir olguda mediastinit gibi ileri komplikasyon gelişmediği görüldü. SONUÇ: SPM göğüs ağrısı ve dispne ile prezente olan benign bir durumdur. Tanıda bilgisayarlı tomografi altın standarttır ve genelde konservatif yollarla tedavi edilir. Nüks nadir olmakla birlikte tanı anında sekonder bir nedenin SPM'ye yol açıp açmadığının belirlenmesi hayati önem taşımaktadır.

DergiPark (Istanbul University), May 21, 2022

Journal of health sciences and medicine, Sep 25, 2022

Aim: This study examines the morbidity and mortality of chest traumas due to Pat-Pat accidents, w... more Aim: This study examines the morbidity and mortality of chest traumas due to Pat-Pat accidents, which is one of the most frequently used motor vehicles in agriculture, especially in mountainous regions in developing countries. Material and Method: This retrospective study included 57 patients who were followed up in a single center between November 2018 and 2021 for thoracic trauma due to a Pat-Pat accident. Patients' age, gender, position in the vehicle, trauma mechanism, trauma location and time, trauma-related pathologies, treatments, and length of stay in hospital and intensive care unit were examined. Results: The cases included 44 (77.2%) men and 13 (22.8%) women with a mean age of 49.93±20.9 years. Of the accidents, 54 (94.7%) occurred on rural roads, 35 (61.4%) occurred on weekdays, 29 (50.9%) occurred in spring, and 20 (35.1%) occurred in summer. The cases consisted of 37 (64.9%) drivers and 20 (35.1%) passengers, of which 31 (54.4%) were injured due to collision and 26 (45.6%) were injured due to vehicle overturning and being ejected from the vehicle. All cases had rib fractures, 8 (14%) had sternum fracture, 25 (43.9%) had pneumothorax, 36 (63.2%) had hemothorax, 22 (38.6%) had pulmonary contusion, and 2 (3.5%) had cardiac contusion. While 19 (33.3%) of the cases were discharged after evaluation and treatment in the emergency department, 30 (52.6%) were treated in the ward, and 8 (14%) were treated in the intensive care unit (ICU). Thirty-three patients underwent a surgical procedure. The mean hospital stay was 7.8 days, and the mean ICU stay was 5.47 days. Mortality developed in 3 (5.3%) cases. The rates of ICU admission and mortality were found to be higher in injuries caused by being ejected from the vehicle compared to injuries caused by impact (p<0.05). Conclusion: Pat-Pat accidents cause severe thoracic trauma. In these vehicle accidents with no significant safety precautions, morbidity and mortality are quite high, especially in thoracic trauma caused by ejection from a vehicle.

Experimental and Clinical Transplantation, Mar 1, 2023

Experimental and Clinical Transplantation, Jun 1, 2023

Asian Journal of Surgery, May 1, 2022