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Papers by Mujahid Mohammed
Letters in Applied Microbiology, 1993
The growth of antibiotic‐sensitive salmonellas in hydrated animal feed incubated at 37°C was rela... more The growth of antibiotic‐sensitive salmonellas in hydrated animal feed incubated at 37°C was relatively unaffected by high concentrations (> 800 ppm) of bacteriostatic agents such as chlortetracycline. On the other hand, they were killed by low concentrations (< 50 ppm) of bactericidal agents such as ampicillin or furazolidone. The aminoglycoside antibiotics apramycin and neomycin killed the salmonellas when present at concentrations in excess of those likely to be recommended for therapeutic purposes (> 300 ppm).
World Journal of Microbiology and Biotechnology
ChemistrySelect, May 18, 2022
World Journal of Microbiology & Biotechnology, Feb 14, 2023
Revista do NUFEN, 2017
Multiplicities in continuous formation: what can a public school in youth and adults modality? Mu... more Multiplicities in continuous formation: what can a public school in youth and adults modality? Multiplicidades en formación continua: ¿Qué puede una escuela pública en la modalidad de jóvenes y adultos?
Revista do NUFEN, 2017
Multiplicities in continuous formation: what can a public school in youth and adults modality? Mu... more Multiplicities in continuous formation: what can a public school in youth and adults modality? Multiplicidades en formación continua: ¿Qué puede una escuela pública en la modalidad de jóvenes y adultos?
Aim: This study was aimed to assess the protecting impact of Emblica officinalis (E.officinalis) ... more Aim: This study was aimed to assess the protecting impact of Emblica officinalis (E.officinalis) and monocot genus officinalae (Z.officinalae) leaf extract on reactive element species, inhibitor potential changes in arsenic and leadevoked toxicity in male rats. Experimental Design: Adult male Wistar rats were used and divided as Group I: Control; Group II: lead and sodium arsenite together were administered through gastric intubation during 14 consecutive days Group III to Group IX: arsenic and lead induced rats treated with ethanolic extract of Emblica officinalis, Z.officinalae orally for 45 days with different concentrations). At the end of the treatment, control and experimental animals were subjected to oxidative stress markers such as H2O2, *OH, and lipid peroxidation (LPO), antioxidant enzymes of Brain and Testis. Results: arsenic and lead evoked rats showed a major increase within the levels of reactive element species (H2O2, OH* and LPO) with concomitant alterations within ...
Journal of Plant Development, 2020
Phytochemical and antimicrobial screening is the extraction, analysis and identification of the b... more Phytochemical and antimicrobial screening is the extraction, analysis and identification of the bioactive components found in plants and the effects of such bio-active components against bacterial species. The analysis were conducted on three plant samples: Vernonia amygdalina (Bitter leaf), Telfairia occidentalis (Pumpkin leaf) and Ocimum gratissimum (Scent leaf). The leaf samples were collected from the Botanical Garden of the department of Biological Sciences Ibrahim Badamasi
Research and Reviews: Journal of Microbiology and Biotechnology, 2015
Probiotics are exclusive definitions of particular microorganisms and evaluated populaces of live... more Probiotics are exclusive definitions of particular microorganisms and evaluated populaces of live microscopic organisms that are proposed to present a medical advantage on the host. These diverse strains and mixes of microorganisms have a wide and changing scope of clinical and immunologic limits that can alter intestinal microbial populaces in ways that can advantage the host
Research and Reviews: Journal of Microbiology and Biotechnology, 2015
Malaria is a vector borne disease is the deadly most important life threatening diseases around t... more Malaria is a vector borne disease is the deadly most important life threatening diseases around the world, According WHO estimates that malaria kills about 660000 people per year. In the present commentary discussion about the focusing on malaria status from the past to the future and need of vaccination rather work on the anti malarial drugs which may results side effects.
Synthetic microbial ecology has the potential to enhance the productivity and resiliency of biote... more Synthetic microbial ecology has the potential to enhance the productivity and resiliency of biotechnology processes compared to approaches using single isolates. Engineering microbial consortia is challenging; however, one approach that has attracted significant attention is the creation of synthetic obligate mutualism using auxotrophic mutants that depend on each other for exchange or cross-feeding of metabolites. Here, we describe the integration of mutant library fitness profiling with mass spectrometry based exometabolomics as a method for constructing synthetic mutualism based on cross-feeding. Two industrially important species lacking known ecological interactions, Zymomonas mobilis and Escherichia coli, were selected as the test species. Amino acids exometabolites identified in the spent medium of Z. mobilis were used to select three corresponding E. coli auxotrophs (proA, pheA and IlvA), as potential E. coli counterparts for the co-culture. A pooled mutant fitness assay wit...
Zika virus is a vector-borne flavivirus that serves a public health emergency is a still ongoing ... more Zika virus is a vector-borne flavivirus that serves a public health emergency is a still ongoing epidemic in the under developing countries, mostly Latin America. This uncertain virus was limited to sporadic cases in Africa and Asia until the emergence of Zika virus in Brazil in 2015 when it rapidly spread everywhere the Americas. Most of the Zika virus infections found to be subclinical or characterised by mild hot disease. However, neurological difficulties, including Guillain-Barre syndrome in adults, and congenital aberrations, including microcephaly in infants born to infected mothers, raised a serious concern. Currently, there is no specific antiviral medication or vaccine ready for Zika virus infection. Thus, global public health response is primarily focused on countering infection, alone in pregnant women, and on implementing up-to-date support to reduce the risk of non-vector transmission of Zika virus
Acquired Immune Deficiency Syndrome (AIDS) was first described but undiscoverable its clinical en... more Acquired Immune Deficiency Syndrome (AIDS) was first described but undiscoverable its clinical entity in 1981 in which the goal remains the same, though at first lifestyle and behavioural factors were hypo the sized to be causally related, finally in 1983 the HIV was identified as the true cause of AIDS. Since the first identity approach to HIV infection shows a divergence in structure and its pathogenesis still emerges as an HIV epidemic and so far resulted in 70 million infections and 35 million deaths in the developed and under developing countries around the globe. HIV infection increases the risk of several autoimmune diseases; the most frequent damages concern the several other organs are the concern. As for as concern on the antiviral therapy and condoms can help to reduce the immunological impact of the disease but it brings up uncountable disadvantages—not the least of which is that they are also good job at which they were originally developed, namely contraception. For th...
Journal of gastroenterology, Jan 11, 2017
Daclatasvir (DCV) and asunaprevir (ASV) combination therapy has been primarily used in patients w... more Daclatasvir (DCV) and asunaprevir (ASV) combination therapy has been primarily used in patients without NS5A L31 or Y93 resistance-associated substitutions (RASs) before treatment. We examined the characteristics of patients without these baseline RASs who did not achieve hepatitis C virus eradication with DCV and ASV combination therapy and identified new baseline NS5A RASs that are closely associated with failure of combination therapy. Three hundred thirty-five patients with hepatitis C virus genotype 1 infection with no NS5A L31, NS5A Y93, and NS3 D168 RASs before DCV and ASV combination therapy and no history of protease inhibitor therapy were enrolled. All RASs were evaluated by direct sequencing. Sustained virologic response at 12 weeks (SVR12) was achieved in 297 patients (89%). Patients with NS5A Q24, L28, and/or R30 RASs or concomitant NS5A F37 and Q54 RASs had a significantly lower SVR12 rate than patients without these RASs (70% vs 92%, p < 0.001 and 79% vs 92%, p = 0...
Scientific Reports
Melanins are chemically diverse ubiquitous pigments found across the life forms synthesized via d... more Melanins are chemically diverse ubiquitous pigments found across the life forms synthesized via different biochemical pathways mainly from L-tyrosine or acetyl CoA. Though few reports suggest the possibility of tryptophan-based melanin synthesis, however, such tryptophan-based melanin and its biosynthesis remained a biochemical riddle. Here we report tryptophan-based melanin production by bacterium, Rubrivivax benzoatilyticus JA2. Aerobic cultures of strain JA2 produced brown pigment when grown on L-tryptophan-containing media. Purified pigment showed typical physico-chemical properties of melanin. Further, extensive spectroscopic studies revealed that pigment is an amorphous, indole-type polymer with stable free radical centers. Further, hydrolysis of the brown pigment revealed the presence of indole moiety, confirming the indolic nature of the pigment. Demonstration of in vitro and in vivo pigment synthesis directly from L-tryptophan or hydroxytryptophan confirms tryptophan-based ...
International Journal of pharma and Bio Sciences
Journal of Hazardous Materials
Letters in Applied Microbiology, 1993
The growth of antibiotic‐sensitive salmonellas in hydrated animal feed incubated at 37°C was rela... more The growth of antibiotic‐sensitive salmonellas in hydrated animal feed incubated at 37°C was relatively unaffected by high concentrations (> 800 ppm) of bacteriostatic agents such as chlortetracycline. On the other hand, they were killed by low concentrations (< 50 ppm) of bactericidal agents such as ampicillin or furazolidone. The aminoglycoside antibiotics apramycin and neomycin killed the salmonellas when present at concentrations in excess of those likely to be recommended for therapeutic purposes (> 300 ppm).
World Journal of Microbiology and Biotechnology
ChemistrySelect, May 18, 2022
World Journal of Microbiology & Biotechnology, Feb 14, 2023
Revista do NUFEN, 2017
Multiplicities in continuous formation: what can a public school in youth and adults modality? Mu... more Multiplicities in continuous formation: what can a public school in youth and adults modality? Multiplicidades en formación continua: ¿Qué puede una escuela pública en la modalidad de jóvenes y adultos?
Revista do NUFEN, 2017
Multiplicities in continuous formation: what can a public school in youth and adults modality? Mu... more Multiplicities in continuous formation: what can a public school in youth and adults modality? Multiplicidades en formación continua: ¿Qué puede una escuela pública en la modalidad de jóvenes y adultos?
Aim: This study was aimed to assess the protecting impact of Emblica officinalis (E.officinalis) ... more Aim: This study was aimed to assess the protecting impact of Emblica officinalis (E.officinalis) and monocot genus officinalae (Z.officinalae) leaf extract on reactive element species, inhibitor potential changes in arsenic and leadevoked toxicity in male rats. Experimental Design: Adult male Wistar rats were used and divided as Group I: Control; Group II: lead and sodium arsenite together were administered through gastric intubation during 14 consecutive days Group III to Group IX: arsenic and lead induced rats treated with ethanolic extract of Emblica officinalis, Z.officinalae orally for 45 days with different concentrations). At the end of the treatment, control and experimental animals were subjected to oxidative stress markers such as H2O2, *OH, and lipid peroxidation (LPO), antioxidant enzymes of Brain and Testis. Results: arsenic and lead evoked rats showed a major increase within the levels of reactive element species (H2O2, OH* and LPO) with concomitant alterations within ...
Journal of Plant Development, 2020
Phytochemical and antimicrobial screening is the extraction, analysis and identification of the b... more Phytochemical and antimicrobial screening is the extraction, analysis and identification of the bioactive components found in plants and the effects of such bio-active components against bacterial species. The analysis were conducted on three plant samples: Vernonia amygdalina (Bitter leaf), Telfairia occidentalis (Pumpkin leaf) and Ocimum gratissimum (Scent leaf). The leaf samples were collected from the Botanical Garden of the department of Biological Sciences Ibrahim Badamasi
Research and Reviews: Journal of Microbiology and Biotechnology, 2015
Probiotics are exclusive definitions of particular microorganisms and evaluated populaces of live... more Probiotics are exclusive definitions of particular microorganisms and evaluated populaces of live microscopic organisms that are proposed to present a medical advantage on the host. These diverse strains and mixes of microorganisms have a wide and changing scope of clinical and immunologic limits that can alter intestinal microbial populaces in ways that can advantage the host
Research and Reviews: Journal of Microbiology and Biotechnology, 2015
Malaria is a vector borne disease is the deadly most important life threatening diseases around t... more Malaria is a vector borne disease is the deadly most important life threatening diseases around the world, According WHO estimates that malaria kills about 660000 people per year. In the present commentary discussion about the focusing on malaria status from the past to the future and need of vaccination rather work on the anti malarial drugs which may results side effects.
Synthetic microbial ecology has the potential to enhance the productivity and resiliency of biote... more Synthetic microbial ecology has the potential to enhance the productivity and resiliency of biotechnology processes compared to approaches using single isolates. Engineering microbial consortia is challenging; however, one approach that has attracted significant attention is the creation of synthetic obligate mutualism using auxotrophic mutants that depend on each other for exchange or cross-feeding of metabolites. Here, we describe the integration of mutant library fitness profiling with mass spectrometry based exometabolomics as a method for constructing synthetic mutualism based on cross-feeding. Two industrially important species lacking known ecological interactions, Zymomonas mobilis and Escherichia coli, were selected as the test species. Amino acids exometabolites identified in the spent medium of Z. mobilis were used to select three corresponding E. coli auxotrophs (proA, pheA and IlvA), as potential E. coli counterparts for the co-culture. A pooled mutant fitness assay wit...
Zika virus is a vector-borne flavivirus that serves a public health emergency is a still ongoing ... more Zika virus is a vector-borne flavivirus that serves a public health emergency is a still ongoing epidemic in the under developing countries, mostly Latin America. This uncertain virus was limited to sporadic cases in Africa and Asia until the emergence of Zika virus in Brazil in 2015 when it rapidly spread everywhere the Americas. Most of the Zika virus infections found to be subclinical or characterised by mild hot disease. However, neurological difficulties, including Guillain-Barre syndrome in adults, and congenital aberrations, including microcephaly in infants born to infected mothers, raised a serious concern. Currently, there is no specific antiviral medication or vaccine ready for Zika virus infection. Thus, global public health response is primarily focused on countering infection, alone in pregnant women, and on implementing up-to-date support to reduce the risk of non-vector transmission of Zika virus
Acquired Immune Deficiency Syndrome (AIDS) was first described but undiscoverable its clinical en... more Acquired Immune Deficiency Syndrome (AIDS) was first described but undiscoverable its clinical entity in 1981 in which the goal remains the same, though at first lifestyle and behavioural factors were hypo the sized to be causally related, finally in 1983 the HIV was identified as the true cause of AIDS. Since the first identity approach to HIV infection shows a divergence in structure and its pathogenesis still emerges as an HIV epidemic and so far resulted in 70 million infections and 35 million deaths in the developed and under developing countries around the globe. HIV infection increases the risk of several autoimmune diseases; the most frequent damages concern the several other organs are the concern. As for as concern on the antiviral therapy and condoms can help to reduce the immunological impact of the disease but it brings up uncountable disadvantages—not the least of which is that they are also good job at which they were originally developed, namely contraception. For th...
Journal of gastroenterology, Jan 11, 2017
Daclatasvir (DCV) and asunaprevir (ASV) combination therapy has been primarily used in patients w... more Daclatasvir (DCV) and asunaprevir (ASV) combination therapy has been primarily used in patients without NS5A L31 or Y93 resistance-associated substitutions (RASs) before treatment. We examined the characteristics of patients without these baseline RASs who did not achieve hepatitis C virus eradication with DCV and ASV combination therapy and identified new baseline NS5A RASs that are closely associated with failure of combination therapy. Three hundred thirty-five patients with hepatitis C virus genotype 1 infection with no NS5A L31, NS5A Y93, and NS3 D168 RASs before DCV and ASV combination therapy and no history of protease inhibitor therapy were enrolled. All RASs were evaluated by direct sequencing. Sustained virologic response at 12 weeks (SVR12) was achieved in 297 patients (89%). Patients with NS5A Q24, L28, and/or R30 RASs or concomitant NS5A F37 and Q54 RASs had a significantly lower SVR12 rate than patients without these RASs (70% vs 92%, p < 0.001 and 79% vs 92%, p = 0...
Scientific Reports
Melanins are chemically diverse ubiquitous pigments found across the life forms synthesized via d... more Melanins are chemically diverse ubiquitous pigments found across the life forms synthesized via different biochemical pathways mainly from L-tyrosine or acetyl CoA. Though few reports suggest the possibility of tryptophan-based melanin synthesis, however, such tryptophan-based melanin and its biosynthesis remained a biochemical riddle. Here we report tryptophan-based melanin production by bacterium, Rubrivivax benzoatilyticus JA2. Aerobic cultures of strain JA2 produced brown pigment when grown on L-tryptophan-containing media. Purified pigment showed typical physico-chemical properties of melanin. Further, extensive spectroscopic studies revealed that pigment is an amorphous, indole-type polymer with stable free radical centers. Further, hydrolysis of the brown pigment revealed the presence of indole moiety, confirming the indolic nature of the pigment. Demonstration of in vitro and in vivo pigment synthesis directly from L-tryptophan or hydroxytryptophan confirms tryptophan-based ...
International Journal of pharma and Bio Sciences
Journal of Hazardous Materials